-
2
-
-
18244414803
-
Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor
-
Duesbery NS, Webb CP, Leppla SH, et al. Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor. Science 1998;280:734-7.
-
(1998)
Science
, vol.280
, pp. 734-737
-
-
Duesbery, N.S.1
Webb, C.P.2
Leppla, S.H.3
-
3
-
-
0034672216
-
Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor
-
Vitale G, Bernardi L, Napolitani G, Mock M, Montecucco C. Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor. Biochem J 2000;352:739-45.
-
(2000)
Biochem J
, vol.352
, pp. 739-745
-
-
Vitale, G.1
Bernardi, L.2
Napolitani, G.3
Mock, M.4
Montecucco, C.5
-
4
-
-
0035957358
-
Suppression of ras-mediated transformation and inhibition of tumor growth and angiogenesis by anthrax lethal factor, a proteolytic inhibitor of multiple MEK pathways
-
Duesbery NS, Resau J, Webb CP, et al. Suppression of ras-mediated transformation and inhibition of tumor growth and angiogenesis by anthrax lethal factor, a proteolytic inhibitor of multiple MEK pathways. Proc Natl Acad Sci U S A 2001;98:4089-94.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 4089-4094
-
-
Duesbery, N.S.1
Resau, J.2
Webb, C.P.3
-
5
-
-
0037022666
-
Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase
-
Koo HM, VanBrocklin M, McWilliams MJ, Leppla SH, Duesbery NS, Woude GF. Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase. Proc Natl Acad Sci U S A 2002;99:3052-7.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 3052-3057
-
-
Koo, H.M.1
VanBrocklin, M.2
McWilliams, M.J.3
Leppla, S.H.4
Duesbery, N.S.5
Woude, G.F.6
-
6
-
-
33644690647
-
BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal toxin
-
Abi-Habib RJ, Urieto JO, Liu S, Leppla SH, Duesbery NS, Frankel AE. BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal toxin. Mol Cancer Ther 2005;4:1303-10.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 1303-1310
-
-
Abi-Habib, R.J.1
Urieto, J.O.2
Liu, S.3
Leppla, S.H.4
Duesbery, N.S.5
Frankel, A.E.6
-
7
-
-
33846244614
-
Systemic anthrax lethal toxin therapy produces regressions of subcutaneous human melanoma tumors in athymic nude mice
-
Abi-Habib RJ, Singh R, Leppla SH, et al. Systemic anthrax lethal toxin therapy produces regressions of subcutaneous human melanoma tumors in athymic nude mice. Clin Cancer Res 2006;12:7437-43.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 7437-7443
-
-
Abi-Habib, R.J.1
Singh, R.2
Leppla, S.H.3
-
8
-
-
0842304298
-
TEM8 interacts with the cleaved C5 domain of collagen α3(VI)
-
Nanda A, Carson-Walter EB, Seaman S, et al. TEM8 interacts with the cleaved C5 domain of collagen α3(VI). Cancer Res 2004;64:817-20.
-
(2004)
Cancer Res
, vol.64
, pp. 817-820
-
-
Nanda, A.1
Carson-Walter, E.B.2
Seaman, S.3
-
10
-
-
0035127174
-
Kaposi's sarcoma-associated herpesvirus: A new DNA tumor virus
-
Boshoff C, Chang Y. Kaposi's sarcoma-associated herpesvirus: a new DNA tumor virus. Annu Rev Med 2001;52:453-70.
-
(2001)
Annu Rev Med
, vol.52
, pp. 453-470
-
-
Boshoff, C.1
Chang, Y.2
-
12
-
-
0037772150
-
Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes
-
Montaner S, Sodhi A, Molinolo A, et al. Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes. Cancer Cell 2003;3:23-36.
-
(2003)
Cancer Cell
, vol.3
, pp. 23-36
-
-
Montaner, S.1
Sodhi, A.2
Molinolo, A.3
-
13
-
-
4444252162
-
Kaposi's sarcoma
-
Flore O. Kaposi's sarcoma. Lancet 2004;364:740-1.
-
(2004)
Lancet
, vol.364
, pp. 740-741
-
-
Flore, O.1
-
14
-
-
0028032582
-
Identification and culture of Kaposi's sarcoma-like spindle cells from the peripheral blood of human immunodeficiency virus-1-infected individuals and normal controls
-
Browning PJ, Sechler JM, Kaplan M, et al. Identification and culture of Kaposi's sarcoma-like spindle cells from the peripheral blood of human immunodeficiency virus-1-infected individuals and normal controls. Blood 1994;84:2711-20.
-
(1994)
Blood
, vol.84
, pp. 2711-2720
-
-
Browning, P.J.1
Sechler, J.M.2
Kaplan, M.3
-
15
-
-
0028969818
-
Inflammatory cytokines induce AIDS-Kaposi's sarcoma-derived spindle cells to produce and release basic fibroblast growth factor and enhance Kaposi's sarcoma-like lesion formation in nude mice
-
Samaniego F, Markham PD, Gallo RC, Ensoli B. Inflammatory cytokines induce AIDS-Kaposi's sarcoma-derived spindle cells to produce and release basic fibroblast growth factor and enhance Kaposi's sarcoma-like lesion formation in nude mice. J Immunol 1995;154:3582-92.
-
(1995)
J Immunol
, vol.154
, pp. 3582-3592
-
-
Samaniego, F.1
Markham, P.D.2
Gallo, R.C.3
Ensoli, B.4
-
16
-
-
0031568523
-
Inflammatory cytokines induce endothelial cells to produce and release basic fibroblast growth factor and to promote Kaposi's sarcoma-like lesions in nude mice
-
Samaniego F, Markham PD, Gendelman R, Gallo RC, Ensoli B. Inflammatory cytokines induce endothelial cells to produce and release basic fibroblast growth factor and to promote Kaposi's sarcoma-like lesions in nude mice. J Immunol 1997;158:1887-94.
-
(1997)
J Immunol
, vol.158
, pp. 1887-1894
-
-
Samaniego, F.1
Markham, P.D.2
Gendelman, R.3
Gallo, R.C.4
Ensoli, B.5
-
17
-
-
18244420373
-
Vascular endothelial growth factor and basic fibroblast growth factor present in Kaposi's sarcoma (KS) are induced by inflammatory cytokines and synergize to promote vascular permeability and KS lesion development
-
Samaniego F, Markham PD, Gendelman R, et al. Vascular endothelial growth factor and basic fibroblast growth factor present in Kaposi's sarcoma (KS) are induced by inflammatory cytokines and synergize to promote vascular permeability and KS lesion development. Am J Pathol 1998;152:1433-43.
-
(1998)
Am J Pathol
, vol.152
, pp. 1433-1443
-
-
Samaniego, F.1
Markham, P.D.2
Gendelman, R.3
-
18
-
-
0034282553
-
The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1α
-
Sodhi A, Montaner S, Patel V, et al. The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1α. Cancer Res 2000;60:4873-80.
-
(2000)
Cancer Res
, vol.60
, pp. 4873-4880
-
-
Sodhi, A.1
Montaner, S.2
Patel, V.3
-
19
-
-
0031937076
-
G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator
-
Bais C, Santomasso B, Coso O, et al. G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator. Nature 1998;391:86-9.
-
(1998)
Nature
, vol.391
, pp. 86-89
-
-
Bais, C.1
Santomasso, B.2
Coso, O.3
-
20
-
-
7244242279
-
The small GTPase Rac1 links the Kaposi sarcoma-associated herpesvirus vGPCR to cytokine secretion and paracrine neoplasia
-
Montaner S, Sodhi A, Servitja JM, et al. The small GTPase Rac1 links the Kaposi sarcoma-associated herpesvirus vGPCR to cytokine secretion and paracrine neoplasia. Blood 2004;104:2903-11.
-
(2004)
Blood
, vol.104
, pp. 2903-2911
-
-
Montaner, S.1
Sodhi, A.2
Servitja, J.M.3
-
21
-
-
31544479770
-
The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor as a therapeutic target for the treatment of Kaposi's sarcoma
-
Montaner S, Sodhi A, Ramsdell AK, et al. The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor as a therapeutic target for the treatment of Kaposi's sarcoma. Cancer Res 2006;66:168-74.
-
(2006)
Cancer Res
, vol.66
, pp. 168-174
-
-
Montaner, S.1
Sodhi, A.2
Ramsdell, A.K.3
-
22
-
-
0034049623
-
Optimized production and purification of Bacillus anthracis lethal factor
-
Park S, Leppla SH. Optimized production and purification of Bacillus anthracis lethal factor. Protein Expr Purif 2000;18:293-302.
-
(2000)
Protein Expr Purif
, vol.18
, pp. 293-302
-
-
Park, S.1
Leppla, S.H.2
-
23
-
-
0018004847
-
Picture thresholding using an iterative selection method
-
Ridler T, Calvard S. Picture thresholding using an iterative selection method. IEEE Trans Man Cybern 1978;6:629-32.
-
(1978)
IEEE Trans Man Cybern
, vol.6
, pp. 629-632
-
-
Ridler, T.1
Calvard, S.2
-
24
-
-
0004190656
-
-
Cambridge New York, Cambridge University Press;
-
Seul M, O'Gorman L, Sammon MJ. Practical algorithms for image analysis: description, examples, and code. Cambridge (New York): Cambridge University Press; 2000.
-
(2000)
Practical algorithms for image analysis: Description, examples, and code
-
-
Seul, M.1
O'Gorman, L.2
Sammon, M.J.3
-
25
-
-
0038322024
-
Anthrax lethal factor proteolysis and inactivation of MAPK kinase
-
Chopra AP, Boone SA, Liang X, Duesbery NS. Anthrax lethal factor proteolysis and inactivation of MAPK kinase. J Biol Chem 2003;278:9402-6.
-
(2003)
J Biol Chem
, vol.278
, pp. 9402-9406
-
-
Chopra, A.P.1
Boone, S.A.2
Liang, X.3
Duesbery, N.S.4
-
26
-
-
1642349448
-
Anthrax lethal factor-cleavage products of MAPK (mitogen-activated protein kinase) kinases exhibit reduced binding to their cognate MAPKs
-
Bardwell AJ, Abdollahi M, Bardwell L. Anthrax lethal factor-cleavage products of MAPK (mitogen-activated protein kinase) kinases exhibit reduced binding to their cognate MAPKs. Biochem J 2004;378:569-77.
-
(2004)
Biochem J
, vol.378
, pp. 569-577
-
-
Bardwell, A.J.1
Abdollahi, M.2
Bardwell, L.3
-
27
-
-
0022891493
-
Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process
-
Friedlander AM. Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process. J Biol Chem 1986;261:7123-6.
-
(1986)
J Biol Chem
, vol.261
, pp. 7123-7126
-
-
Friedlander, A.M.1
-
28
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 2000;351:95-105.
-
(2000)
Biochem J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
29
-
-
0035958732
-
Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway
-
Mody N, Leitch J, Armstrong C, Dixon J, Cohen P. Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway. FEBS Lett 2001;502:21-4.
-
(2001)
FEBS Lett
, vol.502
, pp. 21-24
-
-
Mody, N.1
Leitch, J.2
Armstrong, C.3
Dixon, J.4
Cohen, P.5
-
30
-
-
20444385832
-
Activation of p38 has opposing effects on the proliferation and migration of endothelial cells
-
McMullen ME, Bryant PW, Glembotski CC, Vincent PA, Pumiglia KM. Activation of p38 has opposing effects on the proliferation and migration of endothelial cells. J Biol Chem 2005;280:20995-1003.
-
(2005)
J Biol Chem
, vol.280
, pp. 20995-21003
-
-
McMullen, M.E.1
Bryant, P.W.2
Glembotski, C.C.3
Vincent, P.A.4
Pumiglia, K.M.5
-
31
-
-
19344370532
-
B-Raf-dependent expression of vascular endothelial growth factor-A in Kaposi sarcoma-associated herpesvirus-infected human B cells
-
Akula SM, Ford PW, Whitman AG, et al. B-Raf-dependent expression of vascular endothelial growth factor-A in Kaposi sarcoma-associated herpesvirus-infected human B cells. Blood 2005;105:4516-22.
-
(2005)
Blood
, vol.105
, pp. 4516-4522
-
-
Akula, S.M.1
Ford, P.W.2
Whitman, A.G.3
-
32
-
-
85176687055
-
-
Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 1995;270:27489-94.
-
Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 1995;270:27489-94.
-
-
-
-
33
-
-
34247117937
-
Kaposi's sarcoma-associated herpesvirus promotes angiogenesis by inducing angiopoietin-2 expression via AP-1 and Ets1
-
Ye FC, Blackbourn DJ, Mengel M, et al. Kaposi's sarcoma-associated herpesvirus promotes angiogenesis by inducing angiopoietin-2 expression via AP-1 and Ets1. J Virol 2007;81:3980-91.
-
(2007)
J Virol
, vol.81
, pp. 3980-3991
-
-
Ye, F.C.1
Blackbourn, D.J.2
Mengel, M.3
-
34
-
-
0024461206
-
Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis
-
Connolly DT, Heuvelman DM, Nelson R, et al. Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest 1989;84:1470-8.
-
(1989)
J Clin Invest
, vol.84
, pp. 1470-1478
-
-
Connolly, D.T.1
Heuvelman, D.M.2
Nelson, R.3
-
35
-
-
0027097806
-
Interleukin-8 as a macrophage-derived mediator of angiogenesis
-
Koch AE, Polverini PJ, Kunkel SL, et al. Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science 1992;258:1798-801.
-
(1992)
Science
, vol.258
, pp. 1798-1801
-
-
Koch, A.E.1
Polverini, P.J.2
Kunkel, S.L.3
-
36
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Kim KJ, Li B, Winer J, et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993;362:841-4.
-
(1993)
Nature
, vol.362
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
-
37
-
-
0033580889
-
Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF
-
Holash J, Maisonpierre PC, Compton D, et al. Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science 1999;284:1994-8.
-
(1999)
Science
, vol.284
, pp. 1994-1998
-
-
Holash, J.1
Maisonpierre, P.C.2
Compton, D.3
-
38
-
-
33645239866
-
Patterns of antibody response in humans to the anthrax vaccine adsorbed (AVA) primary (six-dose) series
-
Pittman PR, Norris SL, Barrera Oro JG, Bedwell D, Cannon TL, McKee KT, Jr. Patterns of antibody response in humans to the anthrax vaccine adsorbed (AVA) primary (six-dose) series. Vaccine 2006;24:3654-60.
-
(2006)
Vaccine
, vol.24
, pp. 3654-3660
-
-
Pittman, P.R.1
Norris, S.L.2
Barrera Oro, J.G.3
Bedwell, D.4
Cannon, T.L.5
McKee Jr., K.T.6
-
39
-
-
33947109390
-
Effect of aluminum hydroxide adjuvant and formaldehyde in the formulation of rPA anthrax vaccine
-
Little SF, Ivins BE, Webster WM, Norris SL, Andrews GP. Effect of aluminum hydroxide adjuvant and formaldehyde in the formulation of rPA anthrax vaccine. Vaccine 2007;25:2771-7.
-
(2007)
Vaccine
, vol.25
, pp. 2771-2777
-
-
Little, S.F.1
Ivins, B.E.2
Webster, W.M.3
Norris, S.L.4
Andrews, G.P.5
-
40
-
-
35348928068
-
Rat survival to anthrax lethal toxin is likely controlled by a single gene
-
Nye SH, Wittenburg AL, Evans DL, O'Connor JA, Roman RJ, Jacob HJ. Rat survival to anthrax lethal toxin is likely controlled by a single gene. Pharmacogenomics J 2007;2007:1-7.
-
(2007)
Pharmacogenomics J 2007
, pp. 1-7
-
-
Nye, S.H.1
Wittenburg, A.L.2
Evans, D.L.3
O'Connor, J.A.4
Roman, R.J.5
Jacob, H.J.6
-
41
-
-
0005261734
-
Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro
-
Ray LB, Sturgill TW. Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro. Proc Natl Acad Sci U S A 1987;84:1502-6.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 1502-1506
-
-
Ray, L.B.1
Sturgill, T.W.2
|