CAT-2 amplifies the agonist-evoked force of airway smooth muscle by enhancing spermine-mediated phosphatidylinositol-(4)-phosphate-5-kinase-γ activity

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 293, Issue 4, 2007, Pages

  Chen, Hang ^a   MacLeod, Carol ^a   Deng, Bijia ^a   Mason, Lawrence ^a   Kasaian, Marion ^a   Goldman, Samuel ^a   Wolf, Stan ^a   Williams, Cara ^a   Bowman, Michael R ^a  

^a PFIZER INC   (United States)

Author keywords

Lung resistance; Tracheal isometric tension

Indexed keywords

ACETYLCHOLINE; ARGINASE; CARBACHOL; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOPRENALINE; NITROPRUSSIDE SODIUM; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE GAMMA; PHOSPHOLIPASE C; PHOSPHOLIPASE C BETA; SPERMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CAT 2 GENE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE; GENE FUNCTION; LUNG RESISTANCE; MOUSE; MUSCLE FORCE; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE; TRACHEA; TRACHEA MUSCLE;

ACETYLCHOLINE; AIRWAY RESISTANCE; ANIMALS; ARGINASE; CARBACHOL; CATIONIC AMINO ACID TRANSPORTER 2; ENZYME INHIBITORS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); ISOMETRIC CONTRACTION; ISOPROTERENOL; LUNG; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); SPERMINE; TRACHEA;

EID: 35348861447     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00093.2007     Document Type: Article

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