Elucidation of the RNA target of linezolid by using a linezolid-neomycin B heteroconjugate and genomic SELEX

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 24, 2007, Pages 7688-7695

  Kim, Hyun Jin ^a   Kwon, Miyun ^a   Yu, Jaehoon ^a  

^a Seoul National University   (South Korea)

Author keywords

Genomic SELEX; Heteroconjugate; Linezolid; Linezolid specific loop sequences; Neomycin B

Indexed keywords

FRAMYCETIN; LINEZOLID; LINEZOLID NEOMYCIN B CONJUGATE; RNA; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENOME; BINDING AFFINITY; COMBINATORIAL CHEMISTRY; DRUG BINDING; DRUG CONJUGATION; DRUG MECHANISM; DRUG SYNTHESIS; DRUG TARGETING; ESCHERICHIA COLI; RNA BINDING; SURFACE PLASMON RESONANCE;

ACETAMIDES; BASE SEQUENCE; BINDING SITES; BIOTIN; DRUG DELIVERY SYSTEMS; ESCHERICHIA COLI; FRAMYCETIN; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; OXAZOLIDINONES; PROTEIN SYNTHESIS INHIBITORS; RNA PROBES; SELEX APTAMER TECHNIQUE;

ESCHERICHIA COLI;

EID: 35348814500     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.08.053     Document Type: Article

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