Structure-activity relationship of antileishmanials neolignan analogues

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 23, 2007, Pages 7337-7343

  Aveniente, Mário ^a   Pinto, Eduardo F ^c   Santos, Lourivaldo S ^b   Rossi Bergmann, Bartira ^c   Barata, Lauro E S ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b FEDERAL UNIVERSITY OF PARÁ   (Brazil)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Ketoethers; Ketosulfides; Ketosulfones; Ketosulfoxides; Leishmania amazonensis; Leishmania donovani; Neolignans

Indexed keywords

1 (3,4 DIMETHOXY) 2 [(4 METHYLPHENYL)THIO]PROPAN 1 ONE; 1 (3,4 DIMETHOXYPHENYL) 2 (PHENYLTHIO)PROPAN 1 ONE; 1 (3,4 DIMETHOXYPHENYL) 2 [(4 METHYLPHENYL)SULFONYL]PROPAN 1 ONE; 1 (3,4 DIMETHOXYPHENYL) 2 [(4 METHYLPHENYL)THIO]PROPAN 1 ONE; 1 (3,4 DIMETHOXYPHENYL) 2 [2 METHOXY 4 ((1E)PROP 1 EN 1 YL)PHENOXY]PROPAN 1 ONE; 1 (4 CHLOROPHENYL) 2 [(4 CHLOROPHENYL)THIO]ETHANONE; 1 (4 CHLOROPHENYL) 2 [2 (METHYLTHIO)PHENOXY]ETHANONE; 1 PHENYL 2 (PHENYLTHIO)PROPAN 1 ONE; 2 (2,6 DIMETHOXYPHENOXY) 1 (3,4 DIMETHOXYPHENYL)PROPAN 1 ONE; 2 (4 CHLOROPHENOXY) 1 (3,4 DIMETHOXYPHENYL)ETHANONE; 2 [(4 AMINOPHENYL)THIO] 1 (3,4 DIMETHOXYPHENYL)PROPAN 1 ONE; 2 [(4 AMINOPHENYL)THIO] 1 PHENYLPROPAN 1 ONE; 2 [(4 CHLOROPHENYL)SULFINYL] 1 PHENYLPROPAN 1 ONE; 2 [(4 CHLOROPHENYL)SULFONYL] 1 PHENYLPROPAN 1 ONE; 2 [(4 CHLOROPHENYL)THIO] 1 (3,4 DIMETHOXYPHENYL)PROPAN 1 ONE; 2 [(4 CHLOROPHENYL)THIO] 1 PHENYLETHANONE; 2 [(4 CHLOROPHENYL)THIO] 1 PHENYLPROPAN 1 ONE; 2 [(4 CHLOROPHENYL)THIO]PROPAN 1 ONE; 2 [(4 METHYLPHENYL)THIO] 1 PHENYLPROPAN 1 ONE; 2 PHENOXY 1 PHENYLETHANONE; ANTILEISHMANIAL AGENT; NEOLIGNAN; SULFUR; UNCLASSIFIED DRUG;

AMASTIGOTE; ARTICLE; GROWTH INHIBITION; LEISHMANIA DONOVANI; PARASITE; POLYMERIZATION; SKIN LEISHMANIASIS; STRUCTURE ACTIVITY RELATION; VISCERAL LEISHMANIASIS;

ANIMALS; ANTIPROTOZOAL AGENTS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; LEISHMANIA; LEISHMANIASIS; LIGNANS; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; SPECIES SPECIFICITY; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

LEISHMANIA AMAZONENSIS; LEISHMANIA DONOVANI;

EID: 35148898876     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.08.016     Document Type: Article

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