Gut microflora associated characteristics in first-degree relatives of children with celiac disease

Scandinavian Journal of Gastroenterology

Volumn 42, Issue 10, 2007, Pages 1204-1208

  Tjellström, Bo ^a,b   Stenhammar, Lars ^b,c   Högberg, Lotta ^b   Fälth Magnusson, Karin ^c   Magnusson, Karl Eric ^c   Midtvedt, Tore ^a   Sundqvist, Tommy ^c   Houlston, Richard ^d   Popat, Sanjay ^d   Norin, Elisabeth ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Norrkoping Hospital   (Sweden)

^c LINKÖPING UNIVERSITY   (Sweden)

^d INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Celiac disease; Fecal microflora; Fecal tryptic activity relatives; Short chain fatty acids

Indexed keywords

SHORT CHAIN FATTY ACID;

ADOLESCENT; ADULT; AGED; ARTICLE; CELIAC DISEASE; COMPARATIVE STUDY; FECES ANALYSIS; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; INTESTINE FLORA; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PRIORITY JOURNAL; RELATIVE; SCHOOL CHILD;

ADOLESCENT; ADULT; AGE OF ONSET; AGED; BIOPSY; CARBOXYLIC ACIDS; CELIAC DISEASE; CHILD; CHILD, PRESCHOOL; DISCRIMINANT ANALYSIS; FECES; FEMALE; HUMANS; IMMUNOGLOBULIN A; MALE; MIDDLE AGED; NUCLEAR FAMILY; REFERENCE VALUES; TRYPSIN;

EID: 35148884886     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.1080/00365520701320687     Document Type: Article

References (29)

1. Sollid LM. Coeliac disease: dissecting a complex inflammatory disorder. Nat Rev Immunol 2002;9:647-55.
2. Forsberg G, Fahlgren A, Hörstedt P, Hammarstöm S, Hernell O, Hammarström M-L. Presence of bacteria and innate immunity of intestinal epithelium in childhood celiac disease. Am J Gastroenterol 2004;99:894-904.
3. Tjellström B, Stenhammar L, Högberg L, Fälth-Magnusson K, Magnusson K-E, Midtvedt T, et al. Gut microflora associated characteristics in children with celiac disease. Am J Gastroenterol 2005;100:2784-8.
4. Midtvedt T, Björneklett A, Carlstedt-Duke B, Gustafsson BE, Höverstad T, Lingaas E, et al. The influence of antibiotics upon microflora associated characteristics in man and animals. In: Wostman BS, editor. Germfree research; microflora control and its application to the biochemical sciences. Progress in clinical and biological Research, vol. 181. New York: Alan R. Liss Corporation; 1985. pp 241-4.
5. Walker-Smith JA, Guandalini S, Schmitz J, Shmerling DH, Visakorpi JK. Revised criteria for diagnosis of coeliac disease. Arch Dis Child 1990;65:909-11.
6. Stenhammar L, Brandt Å, Wågermark J. A family study of coeliac disease. Acta Paediatr Scand 1982;71:625-8.
7. Högberg L, Fälth-Magnusson K, Grodzinsky E, Stenhammar L. Familial prevalence of coeliac disease: a twenty-year follow-up study. Scand J Gastroenterol 2003;38:61-5.
8. Siigur U, Norin KE, Allgood G, Schlagheck T, Midtvedt T. Concentrations and correlations of faecal short-chain fatty acids and faecal water content in man. Microb Ecol Health Dis 1994;7:287-94.
9. Zijlstra JB, Beukema J, Wothers BG, Byrne BM, Groen A, Dankert J. Pretreatment methods prior to gaschromatographic analysis of volatile fatty acids from faecal samples. Clin Chem Acta 1977;78:243-50.
10. Höverstad T, Björneklett A. Short-chain fatty acids and bowel functions in man. Scand J Gastroenterol 1984;19:1059-65.
11. Midtvedt A-C. The establishment and development of some metabolic activities associated with the intestinal microflora in healthy children [Thesis]. Stockholm, Sweden; 1994.
12. Norin E. Germfree animal characteristics: a study of some functional aspects of intestinal flora in rat and man [Thesis]. Stockholm, Sweden; 1985.
13. Olerup O, Aldener A, Fogdell A. HLA-DQA1 and -DQB1 typing by PCR amplification with sequence specific primers (PCR-SSP) in 2 hours. Tissue Antigens 1993;41:119-34.
14. Marsh MN. Gluten, major histocompatibility complex, and the small intestine. A molecular and immunologic approach to the spectrum of gluten sensitivity ("celiac sprue"). Gastroenterology 1992;102:330-54.
15. Bevan S, Popat S, Houlston RS. Relative power of linkage and transmission disequilibrium test strategies to detect non-HLA linked celiac disease susceptibility genes. Gut 1999;45:668-71.
16. Holopainen P, Mustalahti K, Uimari P, Collin P, Mäki M, Partanen J. Candidate gene regions and genetic heterogeneity in gluten sensitivity. Gut 2001;48:696-701.
17. Ivarsson A, Persson L-Å, Nyström L, Ascher H, Cavell B, Danielsson L, et al. Epidemic of celiac disease in Swedish children. Acta Paediatr 2000;89:165-71.
18. Hollén E, Forslund T, Högberg L, Laurin P, Stenhammar L, Fälth-Magnusson K, et al. Urinary nitric oxide during one year of gluten-free diet with or without oats in children with coeliac disease. Scand J Gastroenterol 2006;41:1272-8.
19. Herulf M, Blomquist L, Ljung T, Weitzberg E, Lundberg JO. Increased rectal nitric oxide in coeliac disease after local challenge with gluten. Scand J Gastroenterol 2001;36:169-73.
20. Sundqvist T, Laurin P, Fälth-Magnusson K, Magnusson KE, Stenhammar L. Significantly increased levels of nitric oxide products in urine of children with celiac disease. J Pediatr Gastroenterol Nutr 1998;27:196-8.
21. Laurin P, Fälth-Magnusson K, Sundqvist T. Increase in nitric oxide urinary products during gluten challenge in children with celiac disease. Scand J Gastroenterol 2003;38:55-60.
22. van Heel DA, West J. Recent advances in coeliac disease. Gut 2006;55:1037-46.
23. Matsumoti T, Hyasaki T, Nishimura Y, Nakamura M. Takeda T, Tabuchi Y, et al. Butyrate induces necrotic cell death in murine colonic epithelial cell MCE301. Biol Pharm Bull 2006;29:2041-5.
24. Van Neuenen MHMC, Venema K, Van der Woude JCJ, Kuiper EJ. The metabolic activity of fecal microbiota from healthy individuals and patients with inflammatory bowel disease. Dig Dis Sci 2004;49:485-91.
25. Cummings JH, Macfarlane GT. A review: The control and consequences of bacterial fermentation in the human colon. J Appl Bacteriol 1991;70:443-59.
26. Benno P, Alam M, Collinder E, Norin E, Midtvedt T. Faecal tryptic activity and excretion of urobilins in 573 healthy subjects living in Sweden, Norway and Scotland. Microb Ecol Health Dis 2003;15:169-75.
27. Stenhammar L, Fälth-Magnusson K, Jansson G, Magnusson K-E, Sundqvist T. Intestinal permeability to inert sugars and different-sized polyethylene glycols in children with celiac disease. J Pediatr Gastroenterol Nutr 1989;9:281-9.
28. Bjarnason I, Marsh MN, Price A, Levi AJ, Peters TJ. Intestinal permeability in patients with coeliac disease and dermatitis herpetiformis. Gut 1985;26:1214-9.
29. Smecuol E, Vazquez H, Sugai E, Niveloni S, Pedreira S, Cabanne A, et al. Sugar tests detect celiac disease among first-degree relatives. Am J Gastroenterol 1999;94:3547-52.