MR evidence of long T2 water in pathological white matter

Journal of Magnetic Resonance Imaging

Volumn 26, Issue 4, 2007, Pages 1117-1121

  Laule, Cornelia ^a   Vavasour, Irene M ^a   Mädler, Burkhard ^a   Kolind, Shannon H ^a   Sirrs, Sandra M ^a   Brief, Elana E ^a   Traboulsee, Anthony L ^a   Moore, G R Wayne ^a   Li, David K B ^a   MacKay, Alex L ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Brain; Long T2; Multiecho T2; White matter

Indexed keywords

ADULT; ARTICLE; BRAIN DISEASE; CELL VACUOLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC VALUE; EXTRACELLULAR FLUID; FEMALE; HUMAN; IMAGE ANALYSIS; MALE; MULTIPLE SCLEROSIS; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PHENYLKETONURIA; PRIORITY JOURNAL; PYRAMIDAL TRACT; SIGNAL DETECTION; WHITE MATTER;

ADOLESCENT; ADULT; BRAIN; CENTRAL NERVOUS SYSTEM; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MODELS, STATISTICAL; MULTIPLE SCLEROSIS; PHENYLKETONURIAS; TIME FACTORS; WATER;

EID: 35148884410     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.21132     Document Type: Article

References (23)

1. MacKay A. Whittall K, Adler J, Li D, Paty D, Graeb D. In vivo visualization of myelin water in brain by magnetic resonance. Magn Reson Med 1994;31:673-677.
2. 2 distributions and water contents in normal human brain. Magn Reson Med 1997;37:34-43.
3. Vavasour IM. Magnetic resonance of human and bovine brain. PhD thesis, Vancouver: University of British Columbia; 1998.
4. Whittall KP, MacKay AL, Li DK, Vavasour IM, Jones CK, Paty DW. Normal-appearing white matter in multiple sclerosis has heterogeneous, diffusely prolonged T(2). Magn Reson Med 2002;47:403-408.
5. 2 relaxation study. J Neurol 2004;251:284-293.
6. Vidarsson L, Conolly SM, Lim KO, Gold GE, Pauly JM. Echo time optimization for linear combination myelin imaging. Magn Reson Med 2005;53:398-407.
7. 2 analysis. Magn Reson Med 2005;53:1415-1422.
8. 2 prep at 1.5 and 3 T. Magn Reson Imaging 2006;24:33-43.
9. Wu Y, Alexander AL, Fleming JO, Duncan ID, Field AS. Myelin water fraction in human cervical spinal cord in vivo. J Comput Assist Tomogr 2006;30:304-306.
10. Sirrs SM, Laule C, Maedler B, et al. Normal appearing white matter In subjects with phenylketonuria: water content, myelin water fraction, and metabolite concentrations. Radiology 2007;242:236-243.
11. Laule C, Kollnd SH, Bjarnason TA, Li DK, Mackay AL. In vivo multiecho T(2) relaxation measurements using variable TR to decrease scan time. Magn Reson Imaging 2007;25:834-839.
12. Skinner MG, Kolind SH, Mackay AL. The effect of varying echo spacing within a multiecho acquisition: better characterization of long-T(2) components. Magn Reson Imaging 2007;25:840-847.
13. Whittall KP, MacKay AL. Quantitative interpretation of NMR relaxation data. J Magn Reson 1989;84:134-152.
14. Lawson CL, Hanson RJ. Solving least squares problems. Englewood Cliffs, NJ: Prentice-Hall; 1974.
15. Fenrich FR, Beaulieu C, Allen PS. Relaxation times and microstructures. NMR Biomed 2001;14:133-139.
16. Crome L, Pare CMB. Phenylketonuria. J Ment Sc 1960;106:S62.
17. Crome L. The association of phenylketonuria with leucodystrophy. J Neurol Neurosurg Psychiatry 1962;25:149-153.
18. Malamud N. Neuropathology of phenylketonuria. J Neuropathol Exp Neurol 1966;25:254-268.
19. 2 in the brain of patients with acute attack of multiple sclerosis. Magn Reson Med 1989;11:337-348.
20. 2 relaxation in the brain of patients with multiple sclerosis. Magn Reson Imaging 1991;9:107-113.
21. 2 relaxation times in multiple sclerosis. J Neurol Sci 1991;104:176-181.
22. Helms G. Volume correction for edema in single-volume proton MR spectroscopy of contrast-enhancing multiple sclerosis lesions. Magn Reson Med 2001;46:256-263.
23. Yagishita A, Nakano I, Oda M, Hirano A. Location of the corticospinal tract in the internal capsule at MR imaging. Radiology 1994;191:455-460.