Increased susceptibility of small intestine to NSAID-provoked ulceration in rats with adjuvant-induced arthritis: Involvement of enhanced expression of TLR4

Life Sciences

Volumn 81, Issue 16, 2007, Pages 1309-1316

  Kato, Shinichi ^a   Ito, Yasuyuki ^a   Nishio, Hikaru ^a   Aoi, Yoko ^a   Amagase, Kikuko ^a   Takeuchi, Koji ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Adjuvant induced arthritis; Indomethacin; Inducible nitric oxide synthase (iNOS); Nitric oxide (NO); Small intestinal ulceration; Toll like receptor 4 (TLR4)

Indexed keywords

AMINOGUANIDINE; DICLOFENAC; FREUND ADJUVANT; INDOMETACIN; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT; TOLL LIKE RECEPTOR 4;

ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE SEVERITY; INTESTINE ULCER; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; SMALL INTESTINE; ULCEROGENESIS; UPREGULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS, EXPERIMENTAL; FREUND'S ADJUVANT; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INTESTINE, SMALL; MACROPHAGES; MALE; NITRIC OXIDE SYNTHASE TYPE II; PEPTIC ULCER; PEROXIDASE; RATS; RATS, INBRED STRAINS; TIME FACTORS; TOLL-LIKE RECEPTOR 4; UP-REGULATION;

AGOUTI; ANIMALIA; RATTUS;

EID: 35148882998     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.08.036     Document Type: Article

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