Substituted 2-pyrrolinone inhibitors of HIV-1 integrase

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 22, 2007, Pages 6155-6159

  Dayam, Raveendra ^a   Al Mawsawi, Laith Q ^a   Neamati, Nouri ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Diketoacids; HIV 1 integrase; Pharmacophore; Structure activity relationship analysis; Substituted pyrrolin 2 ones; Substructure

Indexed keywords

1 [5 (4 FLUOROBENZYL) 2 FURYL] 3 (1,2,4 TRIAZOL 3 YL) 1,3 PROPANEDIONE; 2 PYRROLINONE INHIBITOR; GS 9137; INTEGRASE INHIBITOR; MK 0518; UNCLASSIFIED DRUG;

ARTICLE; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; PHARMACOPHORE; STRUCTURE ACTIVITY RELATION;

FURANS; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HUMANS; MOLECULAR STRUCTURE; ORGANIC CHEMICALS; PYRROLES; QUINOLONES; TRIAZOLES;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 35148879107     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.09.061     Document Type: Article

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