Detection of surfactant proteins A and D in human tear fluid and the human lacrimal system

Investigative Ophthalmology and Visual Science

Volumn 48, Issue 9, 2007, Pages 3945-3953

  Bräuer, Lars ^a   Kindler, Christian ^a   Jäger, Kristin ^a   Sel, Saadettin ^a   Nölle, Bernhard ^b   Pleyer, Uwe ^c   Ochs, Matthias ^d   Paulsen, Friedrich P ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

COLLECTIN; CYTOKINE; MESSENGER RNA; SURFACTANT PROTEIN A; SURFACTANT PROTEIN D;

ACINAR CELL; ADULT; AGED; AQUEOUS HUMOR; ARTICLE; CELL CULTURE; CELL IMMORTALIZATION; CELL LINE; CONJUNCTIVA; CONJUNCTIVA EPITHELIUM; CONTROLLED STUDY; CORNEA; CORNEA DISEASE; CORNEA EPITHELIUM; CORNEA ULCER; DOT HYBRIDIZATION; EPITHELIUM CELL; EYE DISEASE; FEMALE; GENETIC TRANSFECTION; GOBLET CELL; HERPES SIMPLEX KERATITIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATOCONUS; LACRIMAL APPARATUS; LACRIMAL DUCT; LACRIMAL FLUID; LACRIMAL GLAND; MALE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAPHYLOCOCCUS AUREUS; TEAR FILM; WESTERN BLOTTING; ENZYME IMMUNOASSAY; GENETICS; IMMUNOBLOTTING; METABOLISM; MIDDLE AGED;

AGED; AGED, 80 AND OVER; BLOTTING, WESTERN; CELL LINE; CONJUNCTIVA; CORNEA; FEMALE; HUMANS; IMMUNOBLOTTING; IMMUNOENZYME TECHNIQUES; KERATITIS, HERPETIC; KERATOCONUS; LACRIMAL APPARATUS; MALE; MIDDLE AGED; NASOLACRIMAL DUCT; PULMONARY SURFACTANT-ASSOCIATED PROTEIN A; PULMONARY SURFACTANT-ASSOCIATED PROTEIN D; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TEARS;

EID: 35148861531     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.07-0201     Document Type: Article

References (52)

1. McCulley JP, Shine WE. Meibomian gland function and the tear lipid layer. Ocul Surf. 2003;1:97-106.
2. Sullivan DA. Tearful relationships? Sex, hormones, the lacrimal gland, and aqueous-deficient dry eye. Ocul Surf. 2004;2:92-123.
3. Gipson IK, Hori Y, Argueso P, et al. Character of ocular surface mucins and their alteration in dry eye disease. Ocul Surf. 2004;2:131-148.
4. Jumblatt MM, McKenzie RW, Steele PS, Emberts CG, Jumblatt JE. MUC7 expression in the human lacrimal gland and conjunctiva. Cornea. 2003;22:41-45.
5. Paulsen F, Langer G, Hoffmann W, Berry M. Human lacrimal gland mucins. Cell Tissue Res. 2004;316:167-177.
6. Paulsen F. Cell and molecular biology of human lacrimal gland and nasolacrimal duct mucins. Int Rev Cytol. 2006;249:229-279.
7. Paulsen FP, Berry MS. Mucins and TFF peptides of the tear film and lacrimal apparatus. Prog Histochem Cytochem. 2006;41:1-53.
8. Crouch EC. Structure, biologic properties, and expression of surfactant protein D (SP-D). Biochim Biophys Acta. 1998;1408:278-289.
9. Holmskov U. Lung surfactant proteins (SP-A and SP-D) in non-adaptive host responses to infection. J Leukoc Biol. 1999;66:747-752.
10. Hartshorn KL, White MR, Voelker DR, Coburn J, Zaner K, Crouch EC. Mechanism of binding of surfactant protein D to influenza A viruses: importance of binding to haemagglutinin to antiviral activity. Biochem J. 2000;15:449-458.
11. Korfhagen TR, Bruno MD, Ross GF, et al. Altered surfactant function and structure in SP-A gene targeted mice. Proc Natl Acad Sci USA. 1996; 93:9594-9599.
12. van Iwaarden F, Welmers B, Verhoef J, Haagsman HP, van Golde LM. Pulmonary surfactant protein A enhances the host-defense mechanism of rat alveolar macrophages. Am J Respir Cell Mol Biol. 1990;2:91-98.
13. Hawgood S, Benson BJ, Schilling J, Damm D, Clements JA, White RT. Nucleotide and amino acid sequences of pulmonary surfactant protein SP 18 and evidence for cooperation between SP 18 and SP 28-36 in surfactant lipid adsorption. Proc Natl Acad Sci USA. 1987;84:66-70.
14. Suzuki Y, Fujita Y, Kogishi K. Reconstitution of tubular myelin from synthetic lipids and proteins associated with pig pulmonary surfactant. Am Rev Respir Dis. 1989;140:75-81.
15. Dobbs LG, Wright JR, Hawgood S, Gonzalez R, Venstrom K, Nellenbogen J. Pulmonary surfactant and its components inhibit secretion of phosphatidylcholine from cultured rat alveolar type 2 cells. Proc Natl Acad Sci USA. 1987;84:1010-1014.
16. LeVine AM, Kurak KE, Bruno MD, Stark JM, Whitsett JA, Korfhagen TR. Surfactant protein-A-deficient mice are susceptible to Pseudomonas aeruginosa infection. Am J Respir Cell Mol Biol. 1998;19:700-708.
17. LeVine AM, Kurak KE, Wright JR, et al. Surfactant protein-A binds group B streptococcus enhancing phagocytosis and clearance from lungs of surfactant protein-A-deficient mice. Am J Respir Cell Mol Biol. 1999;20:279-286.
18. McCormack FX, Whitsett JA. The pulmonary collectins, SP-A and SP-D, orchestrate innate immunity in the lung. J Clin Invest. 2002;109:707-712.
19. Wright JR. Immunomodulatory functions of surfactant. Physiol Rev. 1997;77:931-962.
20. Crouch E, Wright JR. Surfactant proteins A and D and pulmonary host defense. Annu Rev Physiol. 2001;63:521-554.
21. Hartshorn KL, Crouch E, White MR, et al. Pulmonary surfactant proteins A and D enhance neutrophil uptake of bacteria. Am J Physiol. 1998;274:L958-L969.
22. Sastry K, Ezekowitz RA. Collectins: pattern recognition molecules involved in first line host defense. Curr Opin Immunol. 1993;5:59-66.
23. Crouch EC, Persson A, Griffin GL, Chang D, Senior RM. Interactions of pulmonary surfactant protein D (SP-D) with human blood leukocytes. Am J Respir Cell Mol Biol. 1995;12:410-415.
24. Pikaar JC, Voorhout WF, van Golde LM, Verhoef J, Van Strijp JA, van Iwaarden JF. Opsonic activities of surfactant proteins A and D in phagocytosis of gram-negative bacteria by alveolar macrophages. J Infect Dis. 1995;172:481-489.
25. Ferguson JS, Voelker DR, McCormack FX, Schlesinger LS. Surfactant protein D binds to Mycobacterium tuberculosis bacilli and lipoarabinomannan via carbohydrate-lectin interactions resulting in reduced phagocytosis of the bacteria by macrophages. J Immunol. 1999;163:312-321.
26. Botas C, Poulain F, Akiyama J, et al. Altered surfactant homeostasis and alveolar type 2 cell morphology in mice lacking surfactant protein D. Proc Natl Acad Sci USA. 1998;95:11869-11874.
27. Korfhagen TR, Sheftelyevich V, Burhans MS, et al. Surfactant protein-D regulates surfactant phospholipid homeostasis in vivo. J Biol Chem. 1998;273:28438-28443.
28. Wert SE, Yoshida M, LeVine AM, et al. Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice. Proc Natl Acad Sci USA. 2000;23:5972-5977.
29. LeVine AM, Whitsett JA, Hartshorn KL, Crouch EC, Korfhagen TR. Surfactant protein D enhances clearance of influenza A virus from the lung in vivo. J Immunol. 2001;167:5868-5873.
30. Madsen J, Kliem A, Tornoe I, Skjodt K, Koch C, Holmskov U. Localization of lung surfactant protein D on mucosal surfaces in human tissues. J Immunol. 2000;164:5866-5870.
31. Stahlman MT, Gray ME, Hull WM, Whitsett JA. Immunolocalization of surfactant protein-D (SP-D) in human fetal, newborn, and adult tissues. J Histochem Cytochem. 2002;50:651-660.
32. Akiyama J, Hoffman A, Brown C, et al. Tissue distribution of surfactant proteins A and D in the mouse. J Histochem Cytochem. 2002;50:993-996.
33. Ni M, Evans DJ, Hawgood S, Anders EM, Sack RA, Fleiszig SM. Surfactant protein D is present in human tear fluid and the cornea and inhibits epithelial cell invasion by Pseudomonas aeruginosa. Infect Immun. 2005;73:2147-2156.
34. Dobbie JW, Tasiaux N, Meijers P, et al. Lamellar bodies in synoviocytes, mesothelium and specific epithelia as possible site of auto-antigen in rheumatoid disease. Br J Rheumatol. 1994;33:508-519.
35. Araki-Sasaki K, Ohashi Y, Sasabe T, et al. An SV40-immortalized human corneal epithelial cell line and its characterization. Invest Ophthalmol Vis Sci. 1995;36:614-621.
36. Diebold Y, Calonge M, Enriquez de Salamanca A, et al. Characterization of a spontaneously immortalized cell line (IOBA-NHC) from normal human conjunctiva. Invest Ophthalmol Vis Sci. 2003;44:4263-4274.
37. Fleiszig SM, Kwong MS, Evans DJ, et al. Modification of Pseudomonas aeruginosa interactions with corneal epithelial cells by human tear fluid. Infect Immun. 2003;71:3866-3874.
38. Benson DA, Karsch-Mizrachi I, Lipman DJ, Ostell J, Wheeler DL. GenBank. Nucleic Acids Res. 2006;34:D16-D20.
39. Joe P, Wallen LD, Chapin CJ, et al. Effects of mechanical factors on growth and maturation of the lung in fetal sheep. Am J Physiol. 1997;272:95-105.
40. Crouch E, Parghi D, Kuan SF, Persson A. Surfactant protein D: subcellular localization in nonciliated bronchiolar epithelial cells. Am J Physiol. 1992;263:L60-L66.
41. Kutta H, Steven P, Varoga D, Paulsen FP. TFF peptides in the human false vocal folds of the larynx. Peptides. 2004;25:811-818.
42. Soerensen CM, Nielsen OL, Willis A, Heegaard PM, Holmskov U. Purification, characterization and immunolocalization of porcine surfactant protein D. Immunology. 2005;114:72-82.
43. Fisher JH, Sheftelyevich V, Ho YS, et al. Pulmonary-specific expression of SP-D corrects pulmonary lipid accumulation in SP-D gene-targeted mice. Am J Physiol Lung Cell Mol Physiol. 2000;278:L365-L373.
44. Elhalwagi BM, Zhang M, Ikegami M, et al. Normal surfactant pool sizes and inhibition-resistant surfactant from mice that overexpress surfactant protein A. Am J Respir Cell Mol Biol. 1999;21:380-387.
45. Oberley RE, Ault KA, Neff TL, Khubchandani KR, Crouch EC, Snyder JM. Surfactant proteins A and D enhance the phagocytosis of Chlamydia into THP-1 cells. Am J Physiol Lung Cell Mol Physiol. 2004;296-306.
46. Steven P, Schafer G, Nolle B, Hinz M, Hoffmann W, Paulsen F. Distribution of TFF peptides in corneal disease and pterygium. Peptides. 2004;25:819-825.
47. Paulsen FP, Pufe T, Schaudig U, et al. Detection of natural peptide antibiotics in human nasolacrimal ducts. Invest Ophthalmol Vis Sci. 2001;42:2157-2163.
48. von Bredow C, Hartl D, Schmid K, et al. Surfactant protein D regulates chemotaxis and degranulation of human eosinophils. Clin Exp Allergy. 2006;36:1566-1574.
49. Malhotra R, Haurum J, Thiel S, Jensenius JC, Sim RB. Pollen grains bind to lung alveolar type 2 cells (A549) via lung surfactant protein A (SP-A). Biosci Rep. 1993;13:79-90.
50. Kingma PS, Whitsett JA. In defense of the lung: surfactant protein A and surfactant protein D. Curr Opin Pharmacol. 2006;6:277-283.
51. Hawgood S, Ochs M, Jung A, et al. Sequential targeted deficiency of SP-A and -D leads to progressive alveolar lipoproteinosis and emphysema. Am J Physiol Lung Cell Mol Physiol. 2002;283:1002-1010.
52. Jung A, Allen L, Nyengaard JR, et al. Design-based stereological analysis of the lung parenchymal architecture and alveolar type 2 cells in surfactant protein A and D double deficient mice. Anat Rec. 2005;286:885-890.