Ablation of a small transmembrane protein of Trypanosoma brucei (TbVTC1) involved in the synthesis of polyphosphate alters acidocalcisome biogenesis and function, and leads to a cytokinesis defect

Biochemical Journal

Volumn 407, Issue 2, 2007, Pages 161-170

  Fang, Jianmin ^a   Rohloff, Peter ^a   Miranda, Kildare ^a   Docampo, Roberto ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

Acidocalcisome; Polyphosphate; Protonmotive force; Trypanosoma brucei; Vacuolar H+ pyrophosphatase; Vacuolar transporter chaperone

Indexed keywords

ACIDOCALCISOME; POLYPHOSPHATES; PROTONMOTIVE FORCES; TRYPANOSOMA BRUCEI; VACUOLAR TRANSPORTER CHAPERONE;

BIOLOGICAL MEMBRANES; BIOMARKERS; ELECTRON MICROSCOPY; PHOSPHATES; SYNTHESIS (CHEMICAL);

PROTEINS;

ACIDOCALCISOME; CALCIUM; CHAPERONE; GREEN FLUORESCENT PROTEIN; INORGANIC PYROPHOSPHATASE; MEMBRANE PROTEIN; POLYPHOSPHATE; UNCLASSIFIED DRUG; VACUOLAR TRANSPORTER CHAPERONE 1;

ANALYTIC METHOD; ARTICLE; BIOGENESIS; CELL DEATH; CONTROLLED STUDY; CYTOKINESIS; FRACTIONATION; GENE; GENE EXPRESSION; IMMUNOGOLD ELECTRON MICROSCOPY; NONHUMAN; OSMOTIC STRESS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; RNA INTERFERENCE; SEQUENCE HOMOLOGY; TRYPANOSOMA BRUCEI; VACUOLAR TRANSPORTER CHAPERONE 1 GENE; WESTERN BLOTTING;

ANIMALS; CALCIUM; CYTOKINESIS; MEMBRANE PROTEINS; ORGANELLES; OSMOSIS; POLYPHOSPHATES; PROTON PUMPS; PROTOZOAN PROTEINS; TRYPANOSOMA BRUCEI BRUCEI; VACUOLAR PROTON-TRANSLOCATING ATPASES;

TRYPANOSOMA BRUCEI;

EID: 35048873639     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20070612     Document Type: Article

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