Timed interactions between viral and cellular replication factors during the initiation of SV40 in vitro DNA replication

Biochemical Journal

Volumn 407, Issue 2, 2007, Pages 313-320

  Taneja, Poonam ^a,d   Nasheuer, Heinz Peter ^b   Hartmann, Hella ^c,e   Grosse, Frank ^c   Fanning, Ellen ^a   Weisshart, Klaus ^c,f  

^a VANDERBILT UNIVERSITY   (United States)

^b NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^c FRITZ LIPMANN INSTITUTE   (Germany)

^d MOLECULAR DEVICES CORPORATION   (United States)

^e DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^f CARL ZEISS SMT AG   (Germany)

Author keywords

DNA polymerase primase (Pol); Large T antigen; Protein protein interaction; Replication protein A; Simian virus 40 DNA replication (SV40 DNA replication)

Indexed keywords

BINDING INTERFACES; EXTENSION ACTIVITIES; SIMIAN VIRUS 40;

BINDING SITES; BIOSYNTHESIS; GENE EXPRESSION; PROTEINS;

DNA;

ANTIBODY; DNA POLYMERASE ALPHA PRIMASE; DNA PRIMASE; PEPTIDE; PRIMER RNA; REPLICATION FACTOR A; UNCLASSIFIED DRUG; VIRUS LARGE T ANTIGEN;

ANALYTIC METHOD; ARTICLE; CELL DIVISION; DNA REPLICATION; DNA TEMPLATE; ENZYME BINDING; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; SIMIAN VIRUS 40; VIRUS REPLICATION;

ANTIGENS, VIRAL, TUMOR; DNA REPLICATION; GENE PRODUCTS, POL; MULTIPROTEIN COMPLEXES; PROTEIN BINDING; REPLICATION PROTEIN A; SIMIAN VIRUS 40; TIME FACTORS; VIRAL PROTEINS;

SIMIAN VIRUS 40;

EID: 35048837021     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20070794     Document Type: Article

References (36)

1. Kelly, T. J. (1988) SV40 DNA replication. J. Biol. Chem. 263, 17889-17892
2. Stenlund, A. (2003) Initiation of DNA replication: lessons from viral initiator proteins. Nat. Rev. Mol. Cell Biol. 4, 777-785
3. Simmons, D. T. (2000) SV40 large T antigen functions in DNA replication and transformation. Adv. Virus Res. 55, 75-134
4. Waga, S., Bauer, G. and Stillman, B. (1994) Reconstitution of complete SV40 DNA replication with purified replication factors. J. Biol. Chem. 269, 10923-10934
5. Stauffer, M. E. and Chazin, W. J. (2004) Structural mechanisms of DNA replication, repair, and recombination. J. Biol. Chem. 279, 30915-30918
6. Dornreiter, I., Erdile, L. F., Gilbert, I. U., von Winkler, D., Kelly, T. J. and Fanning, E. (1992) Interaction of DNA polymerase α-primase with cellular replication protein A and SV40 T antigen. EMBO J. 11, 769-776
7. Kim, D. K., Stigger, E. and Lee, S. H. (1996) Role of the 70-kDa subunit of human replication protein A (I). Single-stranded DNA binding activity, but not polymerase stimulatory activity, is required for DNA replication. J. Biol. Chem. 271, 15124-15129
8. Braun, K. A., Lao, Y., He, Z., Ingles, C. J. and Wold, M. S. (1997) Role of protein-protein interactions in the function of replication protein A (RPA): RPA modulates the activity of DNA polymerase α by multiple mechanisms. Biochemistry 36, 8443-8454
9. Weisshart, K., Taneja, P. and Fanning, E. (1998) The replication protein A binding site in simian virus 40 (SV40) T antigen and its role in the initial steps of SV40 DNA replication. J. Virol. 72, 9771-9781
10. Arunkumar, A. I., Klimovich, V., Jiang, X., Ott, R. D., Mizoue, L., Fanning, E. and Chazin, W. J. (2005) Insights into hRPA32 C-terminal domain-mediated assembly of the simian virus 40 replisome. Nat. Struct. Mol. Biol. 12, 332-339
11. Roy, R., Trowbridge, P., Yang, Z., Champoux, J. J. and Simmons, D. T. (2003) The cap region of topoisomerase I binds to sites near both ends of simian virus 40 T antigen. J. Virol. 77, 9809-9816
12. Melendy, T. and Stillman, B. (1993) An interaction between replication protein A and SV40 T antigen appears essential for primosome assembly during SV40 DNA replication. J. Biol. Chem. 268, 3389-3395
13. Collins, K. L. and Kelly, T. J. (1991) The effects of T antigen and replication protein A on the initiation of DNA synthesis by DNA polymerase α-primase. Mol. Cell. Biol. 11, 2108-2115
14. Simmons, D. T., Gai, D., Parsons, R., Debes, A. and Roy, R. (2004) Assembly of the replication initiation complex on SV40 origin DNA. Nucleic Acids Res. 32, 1103-1112
15. Dornreiter, I., Hoss, A., Arthur, A. K. and Fanning, E. (1990) SV40 T antigen binds directly to the large subunit of purified DNA polymerase α. EMBO J. 9, 3329-3336
16. Stadlbauer, F., Brueckner, A., Rehfuess, C., Eckerskorn, C., Lottspeich, F., Förster, V., Tseng, B. Y. and Nasheuer, H. P. (1994) DNA replication in vitro by recombinant DNA-polymerase-α-primase. Eur. J. Biochem. 222, 781-793
17. Soe, K., Dianov, G., Nasheuer, H. P., Bohr, V. A., Grosse, F. and Stevnsner, T. (2001) A human topoisomerase I cleavage complex is recognized by an additional human topoisomerase I molecule in vitro. Nucleic Acids Res. 29, 3195-3203
18. Henricksen, L. A., Umbricht, C. B. and Wold, M. S. (1994) Recombinant replication protein A: expression, complex formation, and functional characterization. J. Biol. Chem. 269, 11121-11132
19. Kolpashchikov, D. M., Weisshart, K., Nasheuer, H. P., Khodyreva, S. N., Fanning, E., Favre, A. and Lavrik, O. I. (1999) Interaction of the p70 subunit of RPA with a DNA template directs p32 to the 3′-end of nascent DNA. FEBS Lett. 450, 131-134
20. Weisshart, K., Forster, H., Kremmer, E., Schlott, B., Grosse, F. and Nasheuer, H. P. (2000) Protein-protein interactions of the primase subunits p58 and p48 with simian virus 40 T antigen are required for efficient primer synthesis in a cell-free system. J. Biol. Chem. 275, 17328-17337
21. Gurney, E. G., Harrison, R. O. and Fenno, J. (1980) Monoclonal antibodies against simian virus 40 T antigens: evidence for distinct sublcasses of large T antigen and for similarities among nonviral T antigens. J. Virol. 34, 752-763
22. Tanaka, S., Hu, S.-Z., Wang, T. S.-F. and Korn, D. (1982) Preparation and preliminary characterization of monoclonal antibodies against human DNA polymerase α. J. Biol. Chem. 257, 8386-8390
23. Weiner, B. M. and Bradley, M. K. (1991) Specific mutation of a regulatory site within the ATP-binding region of simian virus 40 large T antigen. J. Virol. 65, 4973-4984
24. Murakami, Y. and Hurwitz., J. (1993) DNA polymerase α stimulates the ATP-dependent binding of simian virus tumor T antigen to the SV40 origin of replication. J. Biol. Chem. 268, 11018-11027
25. Guo, Z.-S., Gutierrez, C., Heine, U., Sogo, J. M. and DePamphilis, M. L. (1989) Origin auxiliary sequences can facilitate initiation of simian virus 40 DNA replication in vitro as they do in vivo. Mol. Cell. Biol. 9, 3593-3602
26. Maniatis, T., Fritsch, E. F. and Sambrook, J. (1982) Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor
27. Schneider, C., Weisshart, K., Guarino, L. A., Dornreiter, I. and Fanning, E. (1994) Species specific functional interactions of DNA polymerase α-primase with SV40 T antigen require SV40 origin DNA. Mol. Cell. Biol. 14, 3176-3185
28. Dornreiter, I., Copeland, W. C. and Wang, T. S. (1993) Initiation of simian virus 40 DNA replication requires the interaction of a specific domain of human DNA polymerase α with large T antigen. Mol. Cell. Biol. 13, 809-820
29. Kenny, M. K., Schlegel, U., Furneaux, H. and Hurwitz, J. (1990) The role of human single-stranded DNA binding protein and its individual subunits in simian virus 40 DNA replication. J. Biol. Chem. 265, 7693-7700
30. Murakami, Y. and Hurwitz, J. (1993) Functional interactions between SV40 T antigen and other replication proteins at the replication fork. J. Biol. Chem. 268, 11008-11017
31. Trowbridge, P. W., Roy, R. and Simmons, D. T. (1999) Human topoisomerase I promotes initiation of simian virus 40 DNA replication in vitro. Mol. Cell. Biol. 19, 1686-1694
32. Seinsoth, S., Uhlmann-Schiffler, H. and Stahl, H. (2003) Bidirectional DNA unwinding by a ternary complex of T antigen, nucleolin and topoisomerase I. EMBO Rep. 4, 263-268
33. Brill, S. J. and Stillman, B. (1989) Yeast replication factor-A functions in the unwinding of the SV40 origin of DNA replication. Nature 342, 92-95
34. Murakami, Y., Eki, T. and Hurwitz, J. (1992) Studies on the initiation of simian virus 40 replication in vitro: RNA primer synthesis and its elongation. Proc. Natl. Acad. Sci. U.S.A. 89, 952-956
35. Jiang, X., Klimovich, V., Arunkumar, A. I., Hysinger, E. B., Wang, Y., Ott, R. D., Guler, G. D., Weiner, B., Chazin, W. J. and Fanning, E. (2006) Structural mechanism of RPA loading on DNA during activation of a simple pre-replication complex. EMBO J. 25, 5516-5526
36. Kolpashchikov, D. M., Khodyreva, S. N., Khlimankov, D. Y., Wold, M. S., Favre, A. and Lavrik, O. I. (2001) Polarity of human replication protein A binding to DNA. Nucleic Acids Res. 29, 373-379