Human topoisomerase I promotes initiation of simian virus 40 DNA replication in vitro

Molecular and Cellular Biology

Volumn 19, Issue 3, 1999, Pages 1686-1694

  Trowbridge, Pamela W ^a   Roy, Rupa ^a   Simmons, Daniel T ^a  

^a UNIVERSITY OF DELAWARE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE; VIRUS T ANTIGEN;

ANIMAL CELL; ARTICLE; DNA REPLICATION; ENZYME ACTIVITY; ESCHERICHIA COLI; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; SIMIAN VIRUS 40; VIRUS CELL INTERACTION;

ANIMALIA; BOVINAE; DNA VIRUSES; ESCHERICHIA COLI; RNA VIRUSES; SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40;

EID: 0032980423     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.3.1686     Document Type: Article

References (75)

1. Applegren, N., R. J. Hickey, A. M. Kleinschmidt, Q. Zhou, J. Coll, P. Wills, R. Swaby, Y. Wei, J. Y. Quan, M. Y. W. T. Lee, and L. H. Malkas. 1995. Further characterization of the human cell multiprotein DNA replication complex. J. Cell. Biochem. 59:91-107.
2. Been, M. D., R. R. Burgess, and J. J. Champoux. 1984. DNA strand breakage by wheat germ type 1 topoisomerase. Biochim. Biophys. Acta 782:304-312.
3. Borowiec, J., and J. Hurwitz. 1988. ATP stimulates the binding of simian virus 40 (SV40) large tumor antigen to the SV40 origin of replication. Proc. Natl. Acad. Sci. USA 85:64-68.
4. Budd, M. E., W. C. Choe, and J. L. Campbell. 1995. DNA2 encodes a DNA helicase essential for replication of eukaryotic chromosomes. J. Biol. Chem. 270:26766-26769.
5. Bullock, P. A. 1997. The initiation of simian virus 40 DNA replication in vitro. Crit. Rev. Biochem. Mol. Biol. 32:503-568.
6. Champoux, J. J. 1988. Topoisomerase I is preferentially associated with isolated replicating simian virus 40 molecules after treatment of infected cells with camptothecin. J. Virol. 62:3675-3683.
7. Champoux, J. J. 1992. Topoisomerase I is preferentially associated with normal SV40 replicative intermediates, but is associated with both replicating and nonreplicating SV40 DNAs which are deficient in histones. Nucleic Acids Res. 20:3347-3352.
8. Collins, K., and T. J. Kelly. 1991. Effects of T antigen and replication protein A on the initiation of DNA synthesis by DNA polymerase α-primase. Mol. Cell. Biol. 11:2108-2115.
9. Covey, J. M., C. Jaxel, K. W. Kohn, and Y. Pommier. 1989. Protein-linked DNA strand breaks induced in mammalian cells by camptothecin, an inhibitor of topoisomerase I. Cancer Res. 49:5016-5022.
10. Dean, F. B., P. Bullock, Y. Murakami, C. R. Wobbe, L. Weissbach, and J. Hurwitz. 1987. Simian virus 40 (SV40) DNA replication: SV40 large T antigen unwinds DNA containing the SV40 origin of replication. Proc. Natl. Acad. Sci. USA 84:16-20.
11. Dean, F. B., M. Dodson, H. Echols, and J. Hurwitz. 1987. ATP-dependent formation of specialized nucleoprotein structure by simian virus 40 (SV40) large tumor antigen at the SV40 replication origin. Proc. Natl. Acad. Sci. USA 84:8981-8985.
12. Dornreiter, I., W. C. Copeland, and T. S. F. Wang. 1993. Initiation of simian virus 40 DNA replication requires the interaction of a specific domain of human DNA polymerase α with large T antigen. Mol. Cell. Biol. 13:809-820.
13. Dornreiter, I., L. F. Eerdile, I. U. Gilbert, D. von Winkler, T. J. Kelly, and E. Fanning. 1992. Interaction of DNA polymerase α-primase with cellular replication protein A and SV40 T antigen. EMBO J. 11:769-776.
14. Fairman, M. P., and B. Stillman. 1988. Cellular factors required for multiple stages of SV40 DNA replication in vitro. EMBO J. 7:1211-1218.
15. Fotedar, A., D. Cannella, P. Fitzgerald, T. Rousselle, S. Gupta, M. Doree, and R. Fotedar. 1996. Role for cyclin A-dependent kinase in DNA replication in human S phase cell extracts. J. Biol. Chem. 271:31627-31637.
16. Graham, F. L., J. Smiley, W. C. Russell, and R. Nairn. 1977. Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J. Gen. Virol. 36:59-72.
17. Gurney, E. G., R. O. Harrison, and J. Fenno. 1980. Monoclonal antibodies against simian virus 40 T antigens: evidence for distinct subclasses of large T antigen and for similarities among nonviral T antigens. J. Virol. 34:752-763.
18. Haluska, P., Jr., A. Saleem, T. K. Edwards, and E. H. Rubin. 1998. Interaction between the N-terminus of human topoisomerase I and SV40 large T antigen. Nucleic Acids Res. 26:1841-1847.
19. Harlow, E., L. V. Crawford, D. C. Pim, and N. M. Williamson. 1981. Monoclonal antibodies specific for simian virus 40 tumor antigens. J. Virol. 39: 861-869.
20. Hickey, R. J., and L. H. Malkas. 1997. Mammalian cell DNA replication. Crit. Rev. Eukaryotic Gene Expr. 7:125-157.
21. Hsiang, Y. H., R. Hertzberg, S. Hecht, and L. F. Liu. 1985. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J. Biol. Chem. 260:14873-14878.
22. Hua, X. H., and J. Newport. 1998. Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2. J. Cell Biol. 140:271-281.
23. Hughes, P., and G. Baldacci. 1997. A DNA helicase purified by replication protein (RPA) affinity chromatography from mouse FM3A cells. Nucleic Acids Res. 25:3881-3888.
24. Hurwitz, J., F. B. Dean, A. D. Kwong, and S. H. Lee. 1990. The in vitro replication of DNA containing the SV40 origin. J. Biol. Chem. 265:18043-18046.
25. Ishimi, Y. 1997. A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex. J. Biol. Chem. 272:24508-24513.
26. Ishimi, Y., A. Claude, P. Bullock, and Hurwitz. 1988. Complete enzymatic synthesis of DNA containing the SV40 origin of replication. J. Biol. Chem. 263:19723-19733.
27. Ishimi, Y., K. Matsumoto, and R. Ohba. 1994. DNA replication from initiation zones of mammalian cells in a model system. Mol. Cell. Biol. 14:6489-6496.
28. Ishimi, Y., K. Sugasawa, F. Hanaoka, T. Eki, and J. Hurwitz. 1992. Topoisomerase II plays an essential role as a swivelase in the late stage of SV40 chromosome replication in vitro. J. Biol. Chem. 267:462-466.
29. Kobayashi, T., T. Rein, and M. DePamphilis. 1998. Identification of primary initiation sites for DNA replication in the hamster dihydrofolate reductase gene initiation zone. Mol. Cell. Biol. 18:3266-3277.
30. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227:680-685.
31. Lai, J.-S., and W. Herr. 1992. Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations. Proc. Natl. Acad. Sci. USA 89:6958-6962.
32. Lanford, R. E. 1988. Expression of simian virus 40 T antigen in insect cells using a baculovirus expression vector. Virology 167:72-81.
33. Li, C., L. G. Cao, Y. L. Wang, and E. F. Baril. 1993. Further purification and characterization of a multienzyme complex for DNA synthesis in human cells. J. Cell. Biochem. 53:405-419.
34. Li, J. J., and T. J. Kelly. 1984. Simian virus 40 DNA replication in vitro. Proc. Natl. Acad. Sci. USA 81:6973-6977.
35. Li, J. J., and T. J. Kelly. 1985. Simian virus 40 DNA replication in vitro: specificity of initiation and evidence for bidirectional replication. Mol. Cell. Biol. 5:1238-1246.
36. Madden, K. R., and J. J. Champoux. 1992. Overexpression of human topoisomerase I in baby hamster kidney cells: hypersensitivity of clonal isolates to camptothecin. Cancer Res. 52:525-532.
37. Malkas, L. H., R. J. Hickey, C. Li, N. Pederson, and E. F. Baril. 1990. A 21S enzyme complex from HeLa cells that functions in simian virus 40 DNA replication in vitro. Biochemistry 29:6362-6374.
38. Mastrangelo, I. A., P. V. C. Hough, J. S. Wall, M. Dodson, F. B. Dean, and J. Hurwitz. 1989. ATP-dependent assembly of double hexamers of SV40 T antigen at the viral origin of DNA replication. Nature (London) 338:658-662.
39. Matsumoto, T., T. Eki, and J. Hurwitz. 1990. Studies on the initiation and elongation reactions in the simian virus 40 DNA replication system. Proc. Natl. Acad. Sci. USA 87:9712-9716.
40. Melendy, T., and B. Stillman. 1991. Purification of DNA polymerase δ as an essential simian virus 40 DNA replication factor. J. Biol. Chem. 266:1942-1949.
41. Melendy, T., and B. Stillman. 1993. An interaction between replication protein A and SV40 T antigen appears essential for primosome assembly during SV40 DNA replication. J. Biol. Chem. 268:3389-3395.
42. Murakami, M., C. R. Wobbe, L. Weissbach, F. B. Dean, and J. Hurwitz. 1986. Role of DNA polymerase α and DNA primase in simian virus 40 DNA replication in vitro. Proc. Natl. Acad. Sci. USA 83:2869-2873.
43. Murakami, Y., and J. Hurwitz. 1993. Functional interactions between SV40 T antigen and other replication proteins at the replication fork. J. Biol. Chem. 268:11008-11017.
44. Pommier, Y., G. Kohlhagen, C. Wu, and D. T. Simmons. 1998. Mammalian DNA topoisomerase I activity and poisoning by camptothecin are inhibited by simian virus 40 large T antigen. Biochemistry 37:3818-3823.
45. Prelich, G., M. Kostura, D. R. Marshak, M. B. Mathews, and B. Stillman. 1987. The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro. Nature (London) 326:471-475.
46. Prelich, G., and B. Stillman. 1988. Coordinated leading and lagging strand synthesis during SV40 DNA replication in vitro requires PCNA. Cell 53: 117-126.
47. Prelich, G., C. K. Tan, M. Kostura, M. B. Mathews, A. G. So, K. M. Downey, and B. Stillman. 1987. Functional identity of proliferating cell nuclear antigen and a DNA polymerase-δ auxiliary protein. Nature (London) 326:517-520.
48. Roberts, J. M. 1989. Simian virus 40 (SV40) large tumor antigen causes stepwise changes in SV40 origin structure during initiation of DNA replication. Proc. Natl. Acad. Sci. USA 86:3939-3943.
49. Roy, R., et al. Unpublished data.
50. Shin, C. G., and R. M. Snapka. 1990. Patterns of strongly protein-associated simian virus 40 DNA replication intermediates resulting from exposures Io specific topoisomerase poisons. Biochemistry 29:10934-10939.
51. Simanis, V., and D. P. Lane. 1985. An immunoaffinity purification procedure for SV40 large T antigen. Virology 144:88-100.
52. Simmons, D. T., T. Melendy, D. Usher, and B. Stillman. 1996. Simian virus 40 large T antigen binds to topoisomerase I. Virology 222:365-374.
53. Simmons, D. T., R. Roy, L. Chen, D. Gai, and P. W. Trowbridge. 1998. The activity of topoisomerase I is modulated by large T antigen during unwinding of the SV40 origin. J. Biol. Chem. 273:20390-20396.
54. Simmons, D. T., P. W. Trowbridge, and R. Roy. 1998. Topoisomerase I stimulates SV40 T antigen-mediated DNA replication and inhibits T antigen's ability to unwind DNA at nonorigin sites. Virology 242:435-443.
55. Simmons, D. T., et al. Unpublished data.
56. Snapka, R. M. 1986. Topoisomerase inhibitors can selectively interfere with different stages of simian virus 40 DNA replication. Mol. Cell. Biol. 6:4221-4227.
57. Stewart, L., G. C. Ireton, and J. J. Champoux. 1996. The domain organization of human topoisomerase I. J. Biol. Chem. 271:7602-7608.
58. Stewart, L., G. C. Ireton, and J. J. Champoux. 1997. Reconstitution of human topoisomerase I by fragment complementation. J. Mol. Biol. 269: 355-372.
59. Stewart, L., G. C. Ireton, L. H. Parker, K. R. Madden, and J. J. Champoux. 1996. Biochemical and biophysical analyses of recombinant forms of human topoisomerase I. J. Biol. Chem. 271:7593-7601.
60. Stillman, B., R. D. Gerard, R. A. Guggenheimer, and Y. Gluzman. 1985. T antigen and template requirements for SV40 DNA replication in vitro. EMBO J. 4:2933-2939.
61. Stillman, B. W., and Y. Gluzman. 1985. Replication and supercoiling of simian virus 40 DNA in cell extracts from human cells. Mol. Cell. Biol. 5:2051-2060.
62. Sundin, O., and A. Varshavsky. 1980. Terminal stages of SV40 DNA replication proceed via multiply intertwined catenated dimers. Cell 21:103-114.
63. Sundin, O., and A. Varshavsky. 1981. Arrest of segregation leads to accumulation of highly intertwined catenated dimers: dissection of the final stages of SV40 DNA replication. Cell 25:659-669.
64. Tsurimoto, T., and B. Stillman. 1989. Multiple replication factors augment DNA synthesis by the two eukaryotic DNA polymerases, α and δ. EMBO J. 8:3883-3889.
65. Tsurimoto, T., and B. Stillman. 1991. Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase α and δ during initiation of leading and lagging strand synthesis. J. Biol. Chem. 266:1961-1968.
66. Waga, S., G. Bauer, and B. Stillman. 1994. Reconstitution of complete SV40 DNA replication with purified replication factors. J. Biol. Chem. 269:10923-10934.
67. Waga, S., and B. Stillman. 1994. Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro. Nature (London) 369:207-212.
68. Wang, J. C. 1971. Interaction between DNA and an Escherichia coli protein ω. J. Mol. Biol. 55:523-533.
69. Wang, J. C. 1985. DNA topoisomerases. Annu. Rev. Biochem. 54:665-697.
70. Wobbe, C. R., F. Dean, L. Weissbach, and J. Hurwitz. 1985. In vitro replication of duplex circular DNA containing the simian virus 40 DNA origin site. Proc. Natl. Acad. Sci. USA 82:5710-5714.
71. Wobbe, C. R., L. Weissbach, J. A. Borowiec, F. B. Dean, Y. Murakami, P. Bullock, and J. Hurwitz. 1987. Replication of simian virus 40 origin-containing DNA in vitro with purified proteins. Proc. Natl. Acad. Sci. USA 84:1834-1838.
72. Wold, M. S., and T. Kelly. 1988. Purification and characterization of replication protein A, a cellular protein required for in vitro replication of simian virus 40 DNA. Proc. Natl. Acad. Sci. USA 85:2523-2527.
73. Wold, M. S., D. H. Weinberg, D. M. Virshup, J. J. Li, and T. J. Kelly. 1989. Identification of cellular proteins required for simian virus 40 DNA replication. J. Biol. Chem. 264:2801-2809.
74. Yang, L., M. S. Wold, J. J. Li, T. J. Kelly, and L. F. Liu. 1987. Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro. Proc. Natl. Acad. Sci. USA 84:950-954.
75. Zou, L., J. Mitchell, and B. Stillman. 1997. CDC445, a novel yeast gene that functions with the origin recognition complex and Mcm proteins in initiation of DNA replication. Mol. Cell. Biol. 17:553-563.