Male germ cell-specific expression of a novel Patched-domain containing gene Ptchd3

Biochemical and Biophysical Research Communications

Volumn 363, Issue 3, 2007, Pages 757-761

  Fan, Jun ^a   Akabane, Hiroto ^a   Zheng, Xuehai ^a   Zhou, Xuan ^b   Zhang, Li ^b   Liu, Qiang ^b   Zhang, Yong Lian ^b   Yang, Jing ^c,d   Zhu, Guo Zhang ^a  

^a MARSHALL UNIVERSITY   (United States)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^c THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

Hedgehog signaling; Male germ cell specific; Midpiece; Patched; Ptchd3; Sperm

Indexed keywords

ISOPROTEIN; MESSENGER RNA; PROTEIN DERIVATIVE; PROTEIN PATCHED; PTCHD3 PROTEIN; PTCHD3A PROTEIN; PTCHD3B PROTEIN; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; GERM CELL; HUMAN; HUMAN CELL; MALE; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION; TESTIS;

ADULT; ANIMALS; BLOTTING, NORTHERN; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MALE; MICE; PROTEIN ISOFORMS; RATS; RECEPTORS, CELL SURFACE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPERM TAIL; SPERMATOZOA; TESTIS; TIME FACTORS;

ERINACEIDAE; RATTUS;

EID: 34948896536     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.09.047     Document Type: Article

References (17)

1. Bertrand N., and Dahmane N. Sonic hedgehog signaling in forebrain development and its interactions with pathways that modify its effects. Trends Cell Biol. 16 (2006) 597-605
2. Evangelista M., Tian H., and de Sauvage F.J. The hedgehog signaling pathway in cancer. Clin. Cancer Res. 12 (2006) 5924-5928
3. Walterhouse D.O., Lamm M.L., Villavicencio E., and Iannaccone P.M. Emerging roles for hedgehog-patched-Gli signal transduction in reproduction. Biol. Reprod. 69 (2003) 8-14
4. Bitgood M.J., Shen L., and McMahon A.P. Sertoli cell signaling by Desert hedgehog regulates the male germline. Curr. Biol. 6 (1996) 298-304
5. Clark A.M., Garland K.K., and Russell L.D. Desert hedgehog (Dhh) gene is required in the mouse testis for formation of adult-type Leydig cells and normal development of peritubular cells and seminiferous tubules. Biol. Reprod. 63 (2000) 1825-1838
6. Kroft T.L., Patterson J., Won Yoon J., Doglio L., Walterhouse D.O., Iannaccone P.M., and Goldberg E. GLI1 localization in the germinal epithelial cells alternates between cytoplasm and nucleus: upregulation in transgenic mice blocks spermatogenesis in pachytene. Biol. Reprod. 65 (2001) 1663-1671
7. Szczepny A., Hime G.R., and Loveland K.L. Expression of hedgehog signaling components in adult mouse testis. Dev. Dyn. 235 (2006) 3063-3070
8. Turner T.T., Bomgardner D., and Jacobs J.P. Sonic hedgehog pathway genes are expressed and transcribed in the adult mouse epididymis. J. Androl. 25 (2004) 514-522
9. Turner T.T., Bang H.J., Attipoe S.A., Johnston D.S., and Tomsig J.L. Sonic hedgehog pathway inhibition alters epididymal function as assessed by the development of sperm motility. J. Androl. 27 (2006) 225-232
10. Fan J., Akabane H., Graham S.N., Richardson L.L., and Zhu G.Z. Sperm defects in mice lacking a functional Niemann-Pick C1 protein. Mol. Reprod. Dev. 73 (2006) 1284-1291
11. Li P., Chan H.C., He B., So S.C., Chung Y.W., Shang Q., Zhang Y.D., and Zhang Y.L. An antimicrobial peptide gene found in the male reproductive system of rats. Science 291 (2001) 1783-1785
12. Fan J., Graham M., Akabane H., Richardson L.L., and Zhu G.Z. Identification of a novel male germ cell-specific gene TESF-1 in mice. Biochem. Biophys. Res. Commun. 340 (2006) 8-12
13. Chomczynski P., and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162 (1987) 156-159
14. Zhou C.X., Zhang Y.L., Xiao L., Zheng M., Leung K.M., Chan M.Y., Lo P.S., Tsang L.L., Wong H.Y., Ho L.S., Chung Y.W., and Chan H.C. An epididymis-specific β-defensin is important for the initiation of sperm maturation. Nat. Cell Biol. 6 (2004) 458-464
15. Braun R.E., Peschon J.J., Behringer R.R., Brinster R.L., and Palmiter R.D. Protamine 3′-untranslated sequences regulate temporal translational control and subcellular localization of growth hormone in spermatids of transgenic mice. Genes Dev. 3 (1989) 793-802
16. Braun R.E., Lo D., Pinkert C.A., Widera G., Flavell R.A., Palmiter R.D., and Brinster R.L. Infertility in male transgenic mice: disruption of sperm development by HSV-tk expression in postmeiotic germ cells. Biol. Reprod. 43 (1990) 684-693
17. Handel M.A., and Eppig J.J. Sertoli cell differentiation in the testes of mice genetically deficient in germ cells. Biol. Reprod. 20 (1979) 1031-1038