메뉴 건너뛰기




Volumn 8, Issue 3, 2007, Pages 229-239

SERMs for the treatment and prevention of breast cancer

Author keywords

Endometrial cancer; Estrogen receptor; Osteoporosis; Raloxifene; Selective estrogen receptor modulator; Tamoxifen

Indexed keywords

4 HYDROXYTAMOXIFEN; AROMATASE INHIBITOR; ARZOXIFENE; BASEDOXIFENE; FLUOXYMESTERONE; LASOFOXIFENE; PLACEBO; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; UNCLASSIFIED DRUG;

EID: 34948854285     PISSN: 13899155     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11154-007-9034-4     Document Type: Review
Times cited : (73)

References (75)
  • 1
    • 0012015059 scopus 로고
    • Ueber carcinoma mammae [abstract] 18th Congress of the German Society for Surgery
    • Schinzinger A. Ueber carcinoma mammae [abstract] 18th Congress of the German Society for Surgery. Beilage zum Centralblatt fur Chirurgie 1889;16:55-6.
    • (1889) Beilage Zum Centralblatt fur Chirurgie , vol.16 , pp. 55-56
    • Schinzinger, A.1
  • 2
    • 34948821837 scopus 로고
    • 18th Kongress, Berlin, April 24-27, 1889. Berlin (Germany): Hirschwald. Verhandlungen der Deutschen Gesellschaft fur Chirurgie
    • Schinzinger A. Ueber carcinoma mammae [abstract].18th Kongress, Berlin, April 24-27, 1889. Berlin (Germany): Hirschwald. Verhandlungen der Deutschen Gesellschaft fur Chirurgie 1889;28.
    • (1889) Ueber Carcinoma Mammae [Abstract] , vol.28
    • Schinzinger, A.1
  • 3
    • 50549123220 scopus 로고
    • On the treatment of inoperable cases of carcinoma of the mamma: Suggestions for a new method of treatment with illustrative cases
    • Beatson GT. On the treatment of inoperable cases of carcinoma of the mamma: suggestions for a new method of treatment with illustrative cases. Lancet 1896;2:104-7.
    • (1896) Lancet , vol.2 , pp. 104-107
    • Beatson, G.T.1
  • 4
    • 42949121365 scopus 로고
    • On treatment of inoperable cases of carcinoma of the mamma: Suggestions for a new method of treatment with illustrative cases
    • Beatson CT. On treatment of inoperable cases of carcinoma of the mamma: suggestions for a new method of treatment with illustrative cases. Lancet 1896;2:162-5.
    • (1896) Lancet , vol.2 , pp. 162-165
    • Beatson, C.T.1
  • 5
    • 0001464486 scopus 로고
    • Basic guides to the mechanism of estrogen action
    • Jensen EV, Jacobson HI. Basic guides to the mechanism of estrogen action. Recent Progr Hormone Res 1962;18:387-414.
    • (1962) Recent Progr Hormone Res , vol.18 , pp. 387-414
    • Jensen, E.V.1    Jacobson, H.I.2
  • 6
    • 33845929000 scopus 로고    scopus 로고
    • Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer
    • Jordan VC, Brodie AMH. Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer. Steroids 2007;72:7-25.
    • (2007) Steroids , vol.72 , pp. 7-25
    • Jordan, V.C.1    Brodie, A.M.H.2
  • 7
    • 0037364074 scopus 로고    scopus 로고
    • Tamoxifen: A most unlikely pioneering medicine
    • Jordan VC. Tamoxifen: a most unlikely pioneering medicine. Nature Reviews Drug Discovery 2003;2:205-13.
    • (2003) Nature Reviews Drug Discovery , vol.2 , pp. 205-213
    • Jordan, V.C.1
  • 8
    • 0021709492 scopus 로고
    • Biochemical pharmacology of antiestrogen action
    • Jordan VC. Biochemical pharmacology of antiestrogen action. Pharmacol Rev 1984;36:245-76.
    • (1984) Pharmacol Rev , vol.36 , pp. 245-276
    • Jordan, V.C.1
  • 9
    • 0035421182 scopus 로고    scopus 로고
    • Selective estrogen receptor modulation: A personal perspective
    • Jordan VC. Selective estrogen receptor modulation: a personal perspective. Cancer Res 2001;61:5683-7.
    • (2001) Cancer Res , vol.61 , pp. 5683-5687
    • Jordan, V.C.1
  • 10
    • 0032537396 scopus 로고    scopus 로고
    • Tamoxifen for early breast cancer: An overview of the randomised trials
    • EBCTCG
    • EBCTCG. Tamoxifen for early breast cancer: an overview of the randomised trials. Lancet 1998;354:1451-67.
    • (1998) Lancet , vol.354 , pp. 1451-1467
  • 11
    • 0032537990 scopus 로고    scopus 로고
    • Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study
    • Fisher B, Costantino JP, Wickerham DL, Redmond CK, Kavanah M, Cronin WM, et al. Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst 1998;90:1371-88.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1371-1388
    • Fisher, B.1    Costantino, J.P.2    Wickerham, D.L.3    Redmond, C.K.4    Kavanah, M.5    Cronin, W.M.6
  • 12
    • 27944492407 scopus 로고    scopus 로고
    • Tamoxifen for the prevention of breast cancer: Current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study
    • Fisher B, Costantino JP, Wickerham DL, Cecchini RS, Cronin WM, Robidoux A, et al. Tamoxifen for the prevention of breast cancer: current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study. J Natl Cancer Inst 2005;97:1652-62.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1652-1662
    • Fisher, B.1    Costantino, J.P.2    Wickerham, D.L.3    Cecchini, R.S.4    Cronin, W.M.5    Robidoux, A.6
  • 13
    • 0024214940 scopus 로고
    • Chemosuppression of breast cancer with tamoxifen: Laboratory evidence and future clinical investigations
    • Jordan VC. Chemosuppression of breast cancer with tamoxifen: laboratory evidence and future clinical investigations. Cancer Invest 1988;6:589-95.
    • (1988) Cancer Invest , vol.6 , pp. 589-595
    • Jordan, V.C.1
  • 14
    • 0025338591 scopus 로고
    • The development of antiestrogens for the treatment of breast cancer: Eighth Cain Memorial Award Lecture
    • Lerner LJ, Jordan VC. The development of antiestrogens for the treatment of breast cancer: Eighth Cain Memorial Award Lecture. Cancer Res 1990;50:4177-89.
    • (1990) Cancer Res , vol.50 , pp. 4177-4189
    • Lerner, L.J.1    Jordan, V.C.2
  • 15
    • 0346599193 scopus 로고    scopus 로고
    • National use of postmenopausal hormone therapy
    • Hersh AL, Stefanick ML, Stafford RS. National use of postmenopausal hormone therapy. JAMA 2004;291:47-53.
    • (2004) JAMA , vol.291 , pp. 47-53
    • Hersh, A.L.1    Stefanick, M.L.2    Stafford, R.S.3
  • 16
    • 0037434618 scopus 로고    scopus 로고
    • Selective estrogen-receptor modulators-mechanisms of action and application to clinical practice
    • Riggs BL, Hartmann LC. Selective Estrogen-Receptor Modulators-Mechanisms of Action and Application to Clinical Practice. N Engl J Med 2003;348:618-29.
    • (2003) N Engl J Med , vol.348 , pp. 618-629
    • Riggs, B.L.1    Hartmann, L.C.2
  • 17
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women
    • Writing Group for the Women's Health Initiative Investigators
    • Writing Group for the Women's Health Initiative Investigators, Rossouw JEAG, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women. JAMA 2002;288:321-32.
    • (2002) JAMA , vol.288 , pp. 321-332
    • Jeag, R.1    Prentice, R.L.2    Lacroix, A.Z.3    Kooperberg, C.4    Stefanick, M.L.5    Jackson, R.D.6
  • 18
    • 0042018741 scopus 로고    scopus 로고
    • Breast cancer and hormone-replacement therapy in the Million Women Study
    • Million Women Study Collaborators
    • Million Women Study Collaborators. Breast cancer and hormone-replacement therapy in the Million Women Study. Lancet 2003;362:419-27.
    • (2003) Lancet , vol.362 , pp. 419-427
  • 19
    • 28244434377 scopus 로고    scopus 로고
    • Dramatic change in prescribing of hormonal replacement therapy in the Netherlands after publication of the Million Women Study: A follow-up study
    • Faber A, Bouvy ML, Loskamp L, van de Berg PB, Egberts ACG, de Jong-van den Berg LTW. Dramatic change in prescribing of hormonal replacement therapy in the Netherlands after publication of the Million Women Study: a follow-up study. Br J Clin Pharmacol 2005;60:641-7.
    • (2005) Br J Clin Pharmacol , vol.60 , pp. 641-647
    • Faber, A.1    Bouvy, M.L.2    Loskamp, L.3    Vandeberg, P.B.4    Egberts, A.C.G.5    Dejong-Vandenberg, L.T.W.6
  • 21
    • 33749036592 scopus 로고    scopus 로고
    • The science of selective estrogen receptor modulators: Concept to clinical practice
    • Jordan VC. The science of selective estrogen receptor modulators: concept to clinical practice. Clin Cancer Res 2006;12:5010-3.
    • (2006) Clin Cancer Res , vol.12 , pp. 5010-5013
    • Jordan, V.C.1
  • 22
    • 33947714587 scopus 로고    scopus 로고
    • SERMs: Meeting the promise of multifunctional medicines. (Commentary)
    • Jordan VC. SERMs: meeting the promise of multifunctional medicines. (Commentary). J Natl Cancer Inst 2007;99:350-6.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 350-356
    • Jordan, V.C.1
  • 23
    • 0014053604 scopus 로고
    • A new derivative of triphenylethylene: Effect on implantation and mode of action in rats
    • Harper MJ, Walpole AL. A new derivative of triphenylethylene: effect on implantation and mode of action in rats. J Reprod Fertil 1967;13:101-19.
    • (1967) J Reprod Fertil , vol.13 , pp. 101-119
    • Harper, M.J.1    Walpole, A.L.2
  • 24
    • 0015069359 scopus 로고
    • A new anti-oestrogenic agent in late breast cancer. an early clinical appraisal of ICI 46474
    • Cole MP, Jones CT, Todd ID. A new anti-oestrogenic agent in late breast cancer. an early clinical appraisal of ICI 46474. Br J Cancer 1971;25:270-5.
    • (1971) Br J Cancer , vol.25 , pp. 270-275
    • Cole, M.P.1    Jones, C.T.2    Todd, I.D.3
  • 25
    • 0016638259 scopus 로고
    • Tamoxifen (ICI 46,474) and the human carcinoma 8S oestrogen receptor
    • Jordan VC, Koerner S. Tamoxifen (ICI 46,474) and the human carcinoma 8S oestrogen receptor. Eur J Cancer 1975;11:205-6.
    • (1975) Eur J Cancer , vol.11 , pp. 205-206
    • Jordan, V.C.1    Koerner, S.2
  • 26
    • 0016736721 scopus 로고
    • The effect of synthetic anti-oestrogens on the growth and biochemistry of rat mammary tumours
    • Nicholson RI, Golder MP. The effect of synthetic anti-oestrogens on the growth and biochemistry of rat mammary tumours. Eur J Cancer 1975;11:571-9.
    • (1975) Eur J Cancer , vol.11 , pp. 571-579
    • Nicholson, R.I.1    Golder, M.P.2
  • 27
    • 0017098034 scopus 로고
    • Tamoxifen as an antitumour agent: Oestrogen binding as a predictive test for tumour response
    • Jordan VC, Jaspan T. Tamoxifen as an antitumour agent: oestrogen binding as a predictive test for tumour response. J Endocrinol 1976;68:453-60.
    • (1976) J Endocrinol , vol.68 , pp. 453-460
    • Jordan, V.C.1    Jaspan, T.2
  • 28
    • 0015294754 scopus 로고
    • Effect of some triphenylethylenes on oestradiol binding in vitro to macromolecules from uterus and anterior pituitary
    • Skidmore J, Walpole AL, Woodburn J. Effect of some triphenylethylenes on oestradiol binding in vitro to macromolecules from uterus and anterior pituitary. J Endocrinol 1972;52:289-98.
    • (1972) J Endocrinol , vol.52 , pp. 289-298
    • Skidmore, J.1    Walpole, A.L.2    Woodburn, J.3
  • 29
    • 0017665570 scopus 로고
    • A monohydroxylated metabolite of tamoxifen with potent antioestrogenic activity
    • Jordan VC, Collins MM, Rowsby L, Prestwich G. A monohydroxylated metabolite of tamoxifen with potent antioestrogenic activity. J Endocrinol 1977;75:305-16.
    • (1977) J Endocrinol , vol.75 , pp. 305-316
    • Jordan, V.C.1    Collins, M.M.2    Rowsby, L.3    Prestwich, G.4
  • 30
    • 0025251643 scopus 로고
    • Tamoxifen metabolites in patients on long-term adjuvant therapy for breast cancer
    • Langan-Fahey SM, Tormey DC, Jordan VC. Tamoxifen metabolites in patients on long-term adjuvant therapy for breast cancer. Eur J Cancer 1990;26:883-8.
    • (1990) Eur J Cancer , vol.26 , pp. 883-888
    • Langan-Fahey, S.M.1    Tormey, D.C.2    Jordan, V.C.3
  • 31
    • 0002487846 scopus 로고
    • The effectiveness of long term tamoxifen treatment in a laboratory model for adjuvant hormone therapy of breast cancer
    • Jordan VC, Dix CJ, Allen KE. The effectiveness of long term tamoxifen treatment in a laboratory model for adjuvant hormone therapy of breast cancer. Adjuv Ther Cancer 1979;2:19-26.
    • (1979) Adjuv Ther Cancer , vol.2 , pp. 19-26
    • Jordan, V.C.1    Dix, C.J.2    Allen, K.E.3
  • 32
    • 0018906517 scopus 로고
    • Evaluation of the antitumour activity of the non-steroidal antioestrogen monohydroxytamoxifen in the DMBA-induced rat mammary carcinoma model
    • Jordan VC, Allen KE. Evaluation of the antitumour activity of the non-steroidal antioestrogen monohydroxytamoxifen in the DMBA-induced rat mammary carcinoma model. Eur J Cancer 1980;16:239-51.
    • (1980) Eur J Cancer , vol.16 , pp. 239-251
    • Jordan, V.C.1    Allen, K.E.2
  • 33
    • 0019122379 scopus 로고
    • Pharmacology of tamoxifen in laboratory animals
    • Jordan VC, Allen KE, Dix CJ. Pharmacology of tamoxifen in laboratory animals. Cancer Treat Rep 1980;64:745-59.
    • (1980) Cancer Treat Rep , vol.64 , pp. 745-759
    • Jordan, V.C.1    Allen, K.E.2    Dix, C.J.3
  • 34
    • 0024269590 scopus 로고
    • Effects of adjuvant tamoxifen and of cytotoxic therapy on mortality in early breast cancer. An overview of 61 randomized trials among 28,896 women
    • EBCTCG
    • EBCTCG. Effects of adjuvant tamoxifen and of cytotoxic therapy on mortality in early breast cancer. An overview of 61 randomized trials among 28,896 women. N Engl J Med 1988;319:1681-92.
    • (1988) N Engl J Med , vol.319 , pp. 1681-1692
  • 35
    • 0026557343 scopus 로고
    • Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy. 133 randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women
    • EBCTCG
    • EBCTCG. Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy. 133 randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women. Lancet 1992;339:1-15.
    • (1992) Lancet , vol.339 , pp. 1-15
  • 36
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • EBCTCG
    • EBCTCG. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005;365:1687-717.
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 37
    • 0001626384 scopus 로고
    • Antitumour activity of the antioestrogen ICI 46,474 (tamoxifen) in the dimethylbenzanthracene (DMBA)-induced rat mammary carcinoma model
    • Jordan VC. Antitumour activity of the antioestrogen ICI 46,474 (tamoxifen) in the dimethylbenzanthracene (DMBA)-induced rat mammary carcinoma model. J Steroid Biochem 1974;5:354.
    • (1974) J Steroid Biochem , vol.5 , pp. 354
    • Jordan, V.C.1
  • 38
    • 0017078344 scopus 로고
    • Effect of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinoma
    • Jordan VC. Effect of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinoma. Eur J Cancer 1976;12:419-24.
    • (1976) Eur J Cancer , vol.12 , pp. 419-424
    • Jordan, V.C.1
  • 39
    • 0347450835 scopus 로고
    • Tamoxifen and contralateral breast cancer [letter]
    • Cuzick J, Baum M. Tamoxifen and contralateral breast cancer [letter]. Lancet 1985;2:282.
    • (1985) Lancet , vol.2 , pp. 282
    • Cuzick, J.1    Baum, M.2
  • 40
  • 41
    • 0024801278 scopus 로고
    • Projecting individualized probabilities of developing breast cancer for white females who are being examined annually
    • Gail MH, Brinton LA, Byar DP, Corle DK, Green SB, Schairer C, et al. Projecting individualized probabilities of developing breast cancer for white females who are being examined annually. J Natl Cancer Inst 1989;81:1879-86.
    • (1989) J Natl Cancer Inst , vol.81 , pp. 1879-1886
    • Gail, M.H.1    Brinton, L.A.2    Byar, D.P.3    Corle, D.K.4    Green, S.B.5    Schairer, C.6
  • 42
    • 80052059849 scopus 로고    scopus 로고
    • First results from the International Breast Study: A randomized prevention trial
    • IBIS Investigators
    • IBIS Investigators. First results from the International Breast Study: a randomized prevention trial. Lancet 2002;360:817-24.
    • (2002) Lancet , vol.360 , pp. 817-824
  • 43
    • 33750508737 scopus 로고    scopus 로고
    • Optimising endocrine approaches for the chemoprevention of breast cancer. Beyond the Study of Tamoxifen and Raloxifene (STAR) Trial
    • Jordan VC. Optimising endocrine approaches for the chemoprevention of breast cancer. Beyond the Study of Tamoxifen and Raloxifene (STAR) Trial. Eur J Cancer 2006;42:2909-13.
    • (2006) Eur J Cancer , vol.42 , pp. 2909-2913
    • Jordan, V.C.1
  • 44
    • 0021618186 scopus 로고
    • The pharmacology and clinical uses of tamoxifen
    • Furr BJ, Jordan VC. The pharmacology and clinical uses of tamoxifen. Pharmacol Ther 1984;25:127-205.
    • (1984) Pharmacol Ther , vol.25 , pp. 127-205
    • Furr, B.J.1    Jordan, V.C.2
  • 45
    • 0346602691 scopus 로고    scopus 로고
    • Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine
    • Stearns V, Johnson MD, Rae JM, Morocho A, Novielli A, Bhargava P, et al. Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine. J Natl Cancer Inst 2003;95:1758-64.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1758-1764
    • Stearns, V.1    Johnson, M.D.2    Rae, J.M.3    Morocho, A.4    Novielli, A.5    Bhargava, P.6
  • 46
    • 3342932419 scopus 로고    scopus 로고
    • Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen
    • Johnson MD, Zuo H, Lee KH, Trebley JP, Rae JM, Weatherman RV, et al. Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen. Breast Cancer Res Treat 2004;85:151-9.
    • (2004) Breast Cancer Res Treat , vol.85 , pp. 151-159
    • Johnson, M.D.1    Zuo, H.2    Lee, K.H.3    Trebley, J.P.4    Rae, J.M.5    Weatherman, R.V.6
  • 47
    • 19944434201 scopus 로고    scopus 로고
    • CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment
    • Jin Y, Desta Z, Stearns V, Ward B, Ho H, Lee KH, et al. CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment. JNCI 2005;97:30-9.
    • (2005) JNCI , vol.97 , pp. 30-39
    • Jin, Y.1    Desta, Z.2    Stearns, V.3    Ward, B.4    Ho, H.5    Lee, K.H.6
  • 48
    • 33644639136 scopus 로고    scopus 로고
    • Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes
    • Goetz MP, Rae JM, Suman VJ, Safgren SL, Ames MM, Visscher DW, et al. Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes. J Clin Oncol 2005;23:9312-8.
    • (2005) J Clin Oncol , vol.23 , pp. 9312-9318
    • Goetz, M.P.1    Rae, J.M.2    Suman, V.J.3    Safgren, S.L.4    Ames, M.M.5    Visscher, D.W.6
  • 50
    • 14944362665 scopus 로고    scopus 로고
    • Tamoxifen pharmacogenetics moves closer to reality
    • Garber K. Tamoxifen pharmacogenetics moves closer to reality. J Natl Cancer Inst 2005;97:412-3.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 412-413
    • Garber, K.1
  • 51
    • 0023547257 scopus 로고
    • Effects of anti-estrogens on bone in castrated and intact female rats
    • Jordan VC, Phelps E, Lindgren JU. Effects of anti-estrogens on bone in castrated and intact female rats. Breast Cancer Res Treat 1987;10:31-5.
    • (1987) Breast Cancer Res Treat , vol.10 , pp. 31-35
    • Jordan, V.C.1    Phelps, E.2    Lindgren, J.U.3
  • 52
    • 0023430358 scopus 로고
    • Tamoxifen prevents the skeletal effects of ovarian hormone deficiency in rats
    • Turner RT, Wakley GK, Hannon KS, Bell NH. Tamoxifen prevents the skeletal effects of ovarian hormone deficiency in rats. J Bone Miner Res 1987;2:449-56.
    • (1987) J Bone Miner Res , vol.2 , pp. 449-456
    • Turner, R.T.1    Wakley, G.K.2    Hannon, K.S.3    Bell, N.H.4
  • 53
    • 0023930991 scopus 로고
    • Tamoxifen inhibits osteoclast-mediated resorption of trabecular bone in ovarian hormone-deficient rats
    • Turner RT, Wakley GK, Hannon KS, Bell NH. Tamoxifen inhibits osteoclast-mediated resorption of trabecular bone in ovarian hormone-deficient rats. Endocrinology 1988;122:1146-50.
    • (1988) Endocrinology , vol.122 , pp. 1146-1150
    • Turner, R.T.1    Wakley, G.K.2    Hannon, K.S.3    Bell, N.H.4
  • 54
    • 0023229345 scopus 로고
    • Antitumor actions of keoxifene and tamoxifen in the N-nitrosomethylurea- induced rat mammary carcinoma model
    • Gottardis MM, Jordan VC. Antitumor actions of keoxifene and tamoxifen in the N-nitrosomethylurea-induced rat mammary carcinoma model. Cancer Res 1987;47:4020-4.
    • (1987) Cancer Res , vol.47 , pp. 4020-4024
    • Gottardis, M.M.1    Jordan, V.C.2
  • 55
    • 0023263237 scopus 로고
    • Species-specific pharmacology of antiestrogens: Role of metabolism
    • Jordan VC, Robinson SP. Species-specific pharmacology of antiestrogens: role of metabolism. Fed Proc 1987;46:1870-4.
    • (1987) Fed Proc , vol.46 , pp. 1870-1874
    • Jordan, V.C.1    Robinson, S.P.2
  • 56
    • 0023915865 scopus 로고
    • Contrasting actions of tamoxifen on endometrial and breast tumor growth in the athymic mouse
    • Gottardis MM, Robinson SP, Satyaswaroop PG, Jordan VC. Contrasting actions of tamoxifen on endometrial and breast tumor growth in the athymic mouse. Cancer Res 1988;48:812-5.
    • (1988) Cancer Res , vol.48 , pp. 812-815
    • Gottardis, M.M.1    Robinson, S.P.2    Satyaswaroop, P.G.3    Jordan, V.C.4
  • 58
    • 0028208456 scopus 로고
    • Endometrial cancer in tamoxifen-treated breast cancer patients: Findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14 [see comments]
    • Fisher B, Costantino JP, Redmond CK, Fisher ER, Wickerham DL, Cronin WM. Endometrial cancer in tamoxifen-treated breast cancer patients: findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14 [see comments]. J Natl Cancer Inst 1994;86:527-37.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 527-537
    • Fisher, B.1    Costantino, J.P.2    Redmond, C.K.3    Fisher, E.R.4    Wickerham, D.L.5    Cronin, W.M.6
  • 59
    • 0033575083 scopus 로고    scopus 로고
    • The effect of raloxifene on risk of breast cancer in postmenopausal women: Results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation
    • Cummings SR, Eckert S, Krueger KA, Grady D, Powles TJ, Cauley JA, et al. The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation. JAMA 1999;281:2189-97.
    • (1999) JAMA , vol.281 , pp. 2189-2197
    • Cummings, S.R.1    Eckert, S.2    Krueger, K.A.3    Grady, D.4    Powles, T.J.5    Cauley, J.A.6
  • 60
    • 10644283864 scopus 로고    scopus 로고
    • For the CORE investigators continuing outcomes relevant to Evista: Breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene
    • Martino S, Cauley JA, Barrett-Connor E, Powles TJ, Mershon J, Disch D, et al. For the CORE investigators continuing outcomes relevant to Evista: breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene. J Natl Cancer Inst 2004;96:1751-61.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 1751-1761
    • Martino, S.1    Cauley, J.A.2    Barrett-Connor, E.3    Powles, T.J.4    Mershon, J.5    Disch, D.6
  • 61
    • 0035120523 scopus 로고    scopus 로고
    • Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-year results from the MORE trial. Multiple outcomes of raloxifene evaluation
    • Cauley JA, Norton L, Lippman ME, Eckert S, Krueger KA, Purdie DW, et al. Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-year results from the MORE trial. Multiple outcomes of raloxifene evaluation. Breast Cancer Res Treat 2001;65:125-34.
    • (2001) Breast Cancer Res Treat , vol.65 , pp. 125-134
    • Cauley, J.A.1    Norton, L.2    Lippman, M.E.3    Eckert, S.4    Krueger, K.A.5    Purdie, D.W.6
  • 62
    • 0033581212 scopus 로고    scopus 로고
    • Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: Results from a 3-year randomized clinical trial Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators [see comments] [published erratum appears in JAMA 1999 Dec 8;282(22):2124]
    • Ettinger B, Black DM, Mitlak BH, Knickerbocker RK, Nickelsen T, Genant HK, et al. Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators [see comments] [published erratum appears in JAMA 1999 Dec 8;282(22):2124]. JAMA 1999;282:637-45.
    • (1999) JAMA , vol.282 , pp. 637-645
    • Ettinger, B.1    Black, D.M.2    Mitlak, B.H.3    Knickerbocker, R.K.4    Nickelsen, T.5    Genant, H.K.6
  • 63
  • 64
    • 0025300620 scopus 로고
    • Effect of steroidal and nonsteroidal antiestrogens on the growth of a tamoxifen-stimulated human endometrial carcinoma (EnCa101) in athymic mice
    • Gottardis MM, Ricchio ME, Satyaswaroop PG, Jordan VC. Effect of steroidal and nonsteroidal antiestrogens on the growth of a tamoxifen-stimulated human endometrial carcinoma (EnCa101) in athymic mice. Cancer Res 1990;50:3189-92.
    • (1990) Cancer Res , vol.50 , pp. 3189-3192
    • Gottardis, M.M.1    Ricchio, M.E.2    Satyaswaroop, P.G.3    Jordan, V.C.4
  • 65
    • 33745249570 scopus 로고    scopus 로고
    • The Study of Tamoxifen and Raloxifene (STAR): Report of the National Surgical Adjuvant Breast and Bowel Project P-2 Trial
    • Vogel VG, Costantino JP, Wickerham DL, Cronin WM, Cecchini RS, Atkins JN, et al. The Study of Tamoxifen and Raloxifene (STAR): Report of the National Surgical Adjuvant Breast and Bowel Project P-2 Trial. JAMA 2006;295:2727-41.
    • (2006) JAMA , vol.295 , pp. 2727-2741
    • Vogel, V.G.1    Costantino, J.P.2    Wickerham, D.L.3    Cronin, W.M.4    Cecchini, R.S.5    Atkins, J.N.6
  • 66
    • 33845904405 scopus 로고    scopus 로고
    • Chemoprevention of breast cancer with selective estrogen-receptor modulators
    • Jordan VC. Chemoprevention of breast cancer with selective estrogen-receptor modulators. Nat Rev, Cancer 2007;7:46-53.
    • (2007) Nat Rev, Cancer , vol.7 , pp. 46-53
    • Jordan, V.C.1
  • 67
    • 33846259800 scopus 로고    scopus 로고
    • Beyond raloxifene for the prevention of osteoporosis and breast cancer
    • Jordan VC. Beyond raloxifene for the prevention of osteoporosis and breast cancer. Br J Pharmacol. 2007;150:3-4.
    • (2007) Br J Pharmacol , vol.150 , pp. 3-4
    • Jordan, V.C.1
  • 68
    • 0037468902 scopus 로고    scopus 로고
    • Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 2. Clinical considerations and new agents
    • Jordan VC. Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 2. Clinical considerations and new agents. J Med Chem 2003;46:1081-111.
    • (2003) J Med Chem , vol.46 , pp. 1081-1111
    • Jordan, V.C.1
  • 69
    • 2942750157 scopus 로고    scopus 로고
    • Conjugated equine estrogens and global cognitive function in postmenopausal women: Women's Health Initiative Memory Study
    • Espeland MA, Rapp SR, Shumaker SA, Brunner R, Manson JE, Sherwin BB, et al. Conjugated equine estrogens and global cognitive function in postmenopausal women: Women's Health Initiative Memory Study. JAMA 2004;291:2959-68.
    • (2004) JAMA , vol.291 , pp. 2959-2968
    • Espeland, M.A.1    Rapp, S.R.2    Shumaker, S.A.3    Brunner, R.4    Manson, J.E.5    Sherwin, B.B.6
  • 70
    • 2942755831 scopus 로고    scopus 로고
    • Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory Study
    • Shumaker SA, Legault C, Kuller L, Rapp SR, Thal L, Lane DS, et al. Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory Study. JAMA 2004;291:2947-58.
    • (2004) JAMA , vol.291 , pp. 2947-2958
    • Shumaker, S.A.1    Legault, C.2    Kuller, L.3    Rapp, S.R.4    Thal, L.5    Lane, D.S.6
  • 71
    • 0038386058 scopus 로고    scopus 로고
    • Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: The women's health initiative memory study: A randomized controlled trial
    • Shumaker SA, Legault C, Rapp SR, Thal L, Wallace RB, Ockene JK, et al. Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the women's health initiative memory study: a randomized controlled trial. JAMA 2003;289:2651-62.
    • (2003) JAMA , vol.289 , pp. 2651-2662
    • Shumaker, S.A.1    Legault, C.2    Rapp, S.R.3    Thal, L.4    Wallace, R.B.5    Ockene, J.K.6
  • 72
    • 0037534909 scopus 로고    scopus 로고
    • Effect of estrogen plus progestin on stroke in postmenopausal women: The Women's Health Initiative: A randomized trial
    • Wassertheil-Smoller S, Hendrix SL, Limacher M, Heiss G, Kooperberg C, Baird A, et al. Effect of estrogen plus progestin on stroke in postmenopausal women: the Women's Health Initiative: a randomized trial. JAMA 2003;289:2673-84.
    • (2003) JAMA , vol.289 , pp. 2673-2684
    • Wassertheil-Smoller, S.1    Hendrix, S.L.2    Limacher, M.3    Heiss, G.4    Kooperberg, C.5    Baird, A.6
  • 73
    • 15444369820 scopus 로고    scopus 로고
    • Discovery, clinical development, and therapeutic uses of bisphosphonates
    • Licata AA. Discovery, clinical development, and therapeutic uses of bisphosphonates. Ann Pharmacother 2005;39:668-77.
    • (2005) Ann Pharmacother , vol.39 , pp. 668-677
    • Licata, A.A.1
  • 74
    • 0035942513 scopus 로고    scopus 로고
    • Design, synthesis, and preclinical characterization of novel, highly selective indole estrogens
    • Miller CP, Collini MD, Tran BD, Harris HA, Kharode YP, Marzolf JT, et al. Design, synthesis, and preclinical characterization of novel, highly selective indole estrogens. J Med Chem 2001;44:1654-7.
    • (2001) J Med Chem , vol.44 , pp. 1654-1657
    • Miller, C.P.1    Collini, M.D.2    Tran, B.D.3    Harris, H.A.4    Kharode, Y.P.5    Marzolf, J.T.6
  • 75
    • 0032581614 scopus 로고    scopus 로고
    • Discovery and preclinical pharmacology of a novel, potent, nonsteroidal estrogen receptor agonist/antagonist, CP-336156, a diaryltetrahydronaphthalene
    • Rosati RL, Da Silva Jardine P, Cameron KO, Thompson DD, Ke HZ, Toler SM, et al. Discovery and preclinical pharmacology of a novel, potent, nonsteroidal estrogen receptor agonist/antagonist, CP-336156, a diaryltetrahydronaphthalene. J Med Chem 1998;41:2928-31.
    • (1998) J Med Chem , vol.41 , pp. 2928-2931
    • Rosati, R.L.1    Da Silva Jardine, P.2    Cameron, K.O.3    Thompson, D.D.4    Ke, H.Z.5    Toler, S.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.