Can endocrine disruptors influence neuroplasticity in the aging brain?

NeuroToxicology

Volumn 28, Issue 5 SPEC. ISS., 2007, Pages 938-950

  Weiss, Bernard ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Aging; Alzheimer's disease; Androgens; Cognitive function; Endocrine disruption; Estrogens; Neurogenesis; Plasticity; Stroke; Synaptogenesis; Testosterone

Indexed keywords

2,4 DICHLOROPHENOXYACETIC ACID; 4,4' ISOPROPYLIDENEDIPHENOL; ALACHLOR; ALDICARB; ANTINEMATODAL AGENT; ATRAZINE; CADMIUM; CHLORPHENOTANE; DIELDRIN; ENDOCRINE DISRUPTOR; ENDOSULFAN; ESTROGEN; FUNGICIDE; HEAVY METAL; HERBICIDE; INDUSTRIAL CHEMICAL; INSECTICIDE; LEAD; MANCOZEB; NONYLPHENOL; ORGANOPHOSPHATE; ORGANOTIN COMPOUND; PHTHALIC ACID ESTER; PHYTOESTROGEN; PLASTICIZER; PYRETHROID; SEX HORMONE; SURFACTANT; TESTOSTERONE; TRIBUTYLTIN;

AGING; ALZHEIMER DISEASE; ARTICLE; BRAIN DEVELOPMENT; COGNITION; ENVIRONMENTAL ENRICHMENT; ESTROGEN ACTIVITY; HIPPOCAMPUS; HUMAN; LIFE CYCLE; LIFESPAN; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NEUROANATOMY; NONHUMAN; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; STROKE; SYNAPTOGENESIS;

MAMMALIA;

EID: 34948844461     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2007.01.012     Document Type: Article

References (107)

1. Almeida O.P., Waterreus A., Spry N., Flicker L., and Martins R.N. One year follow-up study of the association between chemical castration, sex hormones, beta-amyloid, memory and depression in men. Psychoneuroendocrinology 29 (2004) 1071-1081
2. Altman J. Are new neurons formed in the brains of adult mammals?. Science 135 (1962) 1127-1128
3. Alvarez-Buylla A., and Lim D.A. For the long run: maintaining germinal niches in the adult brain. Neuron 41 (2004) 683-686
4. Andrade A.J., Grande S.W., Talsness C.E., Grote K., and Chahoud I. A dose-response study following in utero and lactational exposure to di-(2-ethylhexyl)-phthalate (DEHP): non-monotonic dose-response and low dose effects on rat brain aromatase activity. Toxicology 227 (2006) 185-192
5. Arlotta P., Magavi S.S., and Macklis J.D. Molecular manipulation of neural precursors in situ: induction of adult cortical neurogenesis. Exp Gerontol 38 (2003) 173-182
6. Au E., and Fishell G. Adult cortical neurogenesis: nuanced, negligible or nonexistent?. Nat Neurosci 9 (2006) 1086-1088
7. Bedard A., Cossette M., Levesque M., and Parent A. Proliferating cells can differentiate into neurons in the striatum of normal adult monkey. Neurosci Lett 328 (2002) 213-216
8. Binder E.F., Schechtman K.B., Birge S.J., Williams D.B., and Kohrt W.M. Effects of hormone replacement therapy on cognitive performance in elderly women. Maturitas 38 (2001) 137-146
9. Boccardi M., Ghidoni R., Govoni S., Testa C., Benussi L., Bonetti M., et al. Effects of hormone therapy on brain morphology of healthy postmenopausal women: a voxel-based morphometry study. Menopause 13 (2006) 584-591
10. Brainard M.S., and Doupe A.J. What songbirds teach us about learning. Nature 417 (2002) 351-358
11. Breedlove S.M., and Jordan C.L. The increasingly plastic, hormone-responsive adult brain. Proc Natl Acad Sci USA 98 (2001) 2956-2957
12. Brinton R.D. Investigative models for determining hormone therapy-induced outcomes in brain: evidence in support of a healthy cell bias of estrogen action. Ann NY Acad Sci 1052 (2005) 57-74
13. Carmichael S.T. Cellular and molecular mechanisms of neural repair after stroke: making waves. Ann Neurol 59 (2006) 735-742
14. Chen J., Magavi S.S., and Macklis J.D. Neurogenesis of corticospinal motor neurons extending spinal projections in adult mice. Proc Natl Acad Sci USA 101 (2004) 16357-16362
15. Cherrier M.M., Craft S., and Matsumoto A.H. Cognitive changes associated with supplementation of testosterone or dihydrotestosterone in mildly hypogonadal men: a preliminary report. J Androl 24 (2003) 568-576
16. Colborn T. Neurodevelopment and endocrine disruption. Environ Health Perspect 112 (2004) 944-949
17. Colborn T., Dumanoski D., and Myers J.M. Our stolen future (1996), Dutton, New York
18. Coleman P.D., and Flood D.G. Neuron numbers and dendritic extent in normal aging and Alzheimer's disease. Neurobiol Aging 8 (1987) 521-545
19. Cooke B.M., and Woolley C.S. Gonadal hormone modulation of dendrites in the mammalian CNS. J Neurobiol 64 (2005) 34-46
20. Dancause N. Vicarious function of remote cortex following stroke: recent evidence from human and animal studies. Neuroscientist 12 (2006) 489-499
21. Dancause N., Barbay S., Frost S.B., Plautz E.J., Chen D., Zoubina E.V., et al. Extensive cortical rewiring after brain injury. J Neurosci 25 (2005) 10167-10179
22. Davies W., and Wilkinson L.S. It is not all hormones: alternative explanations for sexual differentiation of the brain. Brain Res 1126 (2006) 36-45
23. Draganski B., Gaser C., Busch V., Schuierer G., Bogdahn U., and May A. Neuroplasticity: changes in grey matter induced by training. Nature 427 (2004) 311-312
24. Duan H., Wearne S.L., Rocher A.B., Macedo A., Morrison J.H., and Hof P.R. Age-related dendritic and spine changes in corticocortically projecting neurons in macaque monkeys. Cereb Cortex 13 (2003) 950-961
25. Emsley J.G., Mitchell B.D., Kempermann G., and Macklis J.D. Adult neurogenesis and repair of the adult CNS with neural progenitors, precursors, and stem cells. Prog Neurobiol 75 (2005) 321-341
26. Erickson K.I., Colcombe S.J., Raz N., Korol D.L., Scalf P., Webb A., et al. Selective sparing of brain tissue in postmenopausal women receiving hormone replacement therapy. Neurobiol Aging 26 (2005) 1205-1213
27. Espeland M.A., et al. Conjugated equine estrogens and global cognitive function in postmenopausal women: women's health initiative memory study. JAMA 291 (2004) 2959-2968
28. Freundlieb N., Francois C., Tande D., Oertel W.H., Hirsch E.C., and Hoglinger G.U. Dopaminergic substantia nigra neurons project topographically organized to the subventricular zone and stimulate precursor cell proliferation in aged primates. J Neurosci 26 (2006) 2321-2325
29. Gilbert M.E., Kelly M.E., Samsam T.E., and Goodman J.H. Chronic developmental lead exposure reduces neurogenesis in adult rat hippocampus but does not impair spatial learning. Toxicol Sci 86 (2005) 365-374
30. Gladwell M. The tipping point (2000), Little Brown, New York
31. Gore A.C., Heindel J.J., and Zoeller R.T. Endocrine disruption for endocrinologists (and others). Endocrinology 147 (2006) S1-S3
32. Gould E., and Gross C.G. Neurogenesis in adult mammals: some progress and problems. J Neurosci 22 (2002) 619-623
33. Gould E., Woolley C.S., Frankfurt M., and McEwen B.S. Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood. J Neurosci 10 (1990) 1286-1291
34. Gray P.B., Singh A.B., Woodhouse L.J., Storer T.W., Casaburi R., Dzekov J., et al. Dose-dependent effects of testosterone on sexual function, mood, and visuospatial cognition in older men. J Clin Endocrinol Metab 90 (2005) 3838-3846
35. Gray Jr. L.E., Wilson V.S., Stoker T., Lambright C., Furr J., Noriega N., et al. Adverse effects of environmental antiandrogens and androgens on reproductive development in mammals. Int J Androl 29 (2006) 96-104 [discussion 105-8]
36. Gross C.G. Neurogenesis in the adult brain: death of a dogma. Nat Rev Neurosci 1 (2000) 67-73
37. Hao J., Janssen W.G., Tang Y., Roberts J.A., McKay H., Lasley B., et al. Estrogen increases the number of spinophilin-immunoreactive spines in the hippocampus of young and aged female rhesus monkeys. J Comp Neurol 465 (2003) 540-550
38. Hao J., Rapp P.R., Leffler A.E., Leffler S.R., Janssen W.G., Lou W., et al. Estrogen alters spine number and morphology in prefrontal cortex of aged female rhesus monkeys. J Neurosci 26 (2006) 2571-2578
39. Hauser R. The environment and male fertility: recent research on emerging chemicals and semen quality. Semin Reprod Med 24 (2006) 156-167
40. Hebb D.O. The organization of behavior (1949), Wiley, New York
41. Hijazi R.A., and Cunningham G.R. Andropause: is androgen replacement therapy indicated for the aging male?. Annu Rev Med 56 (2005) 117-137
42. Hogervorst E., Bandelow S., Combrinck M., and Smith A.D. Low free testosterone is an independent risk factor for Alzheimer's 2710 disease. Exp Gerontol 39 (2004) 1633-1639
43. Hojo Y., Hattori T.A., Enami T., Furukawa A., Suzuki K., Ishii H.T., et al. Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017alpha and P450 aromatase localized in neurons. Proc Natl Acad Sci USA 101 (2004) 865-870
44. Janowsky J.S. The role of androgens in cognition and brain aging in men. Neuroscience 138 (2006) 1015-1020
45. Janowsky J.S. Thinking with your gonads: testosterone and cognition. Trends Cogn Sci 10 (2006) 77-82
46. Janowsky J.S., Chavez B., and Orwoll E. Sex steroids modify working memory. J Cogn Neurosci 12 (2000) 407-414
47. Jeays-Ward K., Dandonneau M., and Swain A. Wnt4 is required for proper male as well as female sexual development. Dev Biol 276 (2004) 431-440
48. Jin K., Wang X., Xie L., Mao X.O., Zhu W., Wang Y., et al. Evidence for stroke-induced neurogenesis in the human brain. Proc Natl Acad Sci USA 103 (2006) 13198-13202
49. Kempermann G., Gast D., and Gage F.H. Neuroplasticity in old age: sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment. Ann Neurol 52 (2002) 135-143
50. Kempermann G., Gast D., Kronenberg G., Yamaguchi M., and Gage F.H. Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice. Development 130 (2003) 391-399
51. Kempermann G., Wiskott L., and Gage F.H. Functional significance of adult neurogenesis. Curr Opin Neurobiol 14 (2004) 186-191
52. Kety S.S. Human cerebral blood flow and oxygen consumption as related to aging. Res Publ Assoc Res Nerv Ment Dis 35 (1956) 31-45
53. Kozorovitskiy Y., Gross C.G., Kopil C., Battaglia L., McBreen M., Stranahan A.M., et al. Experience induces structural and biochemical changes in the adult primate brain. Proc Natl Acad Sci USA 102 (2005) 17478-17482
54. Kuhn H.G., Dickinson-Anson H., and Gage F.H. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J Neurosci 16 (1996) 2027-2033
55. Labrie F., Luu-The V., Labrie C., and Simard J. DHEA and its transformation into androgens and estrogens in peripheral target tissues: intracrinology. Front Neuroendocrinol 22 (2001) 185-212
56. Labrie F., Luu-The V., Belanger A., Lin S.X., Simard J., Pelletier G., et al. Is dehydroepiandrosterone a hormone?. J Endocrinol 187 (2005) 169-196
57. Leranth C., Roth R.H., Elsworth J.D., Naftolin F., Horvath T.L., and Redmond Jr. D.E. Estrogen is essential for maintaining nigrostriatal dopamine neurons in primates: implications for Parkinson's disease and memory. J Neurosci 20 (2000) 8604-8609
58. Leranth C., Shanabrough M., and Redmond Jr. D.E. Gonadal hormones are responsible for maintaining the integrity of spine synapses in the CA1 hippocampal subfield of female nonhuman primates. J Comp Neurol 447 (2002) 34-42
59. Leranth C., Petnehazy O., and MacLusky N.J. Gonadal hormones affect spine synaptic density in the CA1 hippocampal subfield of male rats. J Neurosci 23 (2003) 1588-1592
60. Leranth C., Prange-Kiel J., Frick K.M., and Horvath T.L. Low CA1 spine synapse density is further reduced by castration in male non-human primates. Cereb Cortex 14 (2004) 503-510
61. Lord C, Buss C, Lupien SJ, Pruessner JC. Hippocampal volumes are larger in postmenopausal women using estrogen therapy compared to past users, never users and men: a possible window of opportunity effect. Neurobiol Aging 2006 [Epub ahead of print].
62. MacLennan A.H., Henderson V.W., Paine B.J., Mathias J., Ramsay E.N., Ryan P., et al. Hormone therapy, timing of initiation, and cognition in women aged older than 60 years: the REMEMBER pilot study. Menopause 13 (2006) 28-36
63. MacLusky N.J., Hajszan T., and Leranth C. The environmental estrogen bisphenol a inhibits estradiol-induced hippocampal synaptogenesis. Environ Health Perspect 113 (2005) 675-679
64. MacLusky N.J., Luine V.N., Hajszan T., and Leranth C. The 17alpha and 17beta isomers of estradiol both induce rapid spine synapse formation in the CA1 hippocampal subfield of ovariectomized female rats. Endocrinology 146 (2005) 287-293
65. MacLusky N.J., Hajszan T., Prange-Kiel J., and Leranth C. Androgen modulation of hippocampal synaptic plasticity. Neuroscience 138 (2006) 957-965
66. Madeira M.D., Ferreira-Silva L., and Paula-Barbosa M.M. Influence of sex and estrus cycle on the sexual dimorphisms of the hypothalamic ventromedial nucleus: stereological evaluation and golgi study. J Comp Neurol 432 (2001) 329-345
67. Main K.M., Mortensen G.K., Kaleva M.M., Boisen K.A., Damgaard I.N., Chellakooty M., et al. Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age. Environ Health Perspect 114 (2006) 270-276
68. Marsee K., Woodruff T.J., Axelrad D.A., Calafat A.M., and Swan S.H. Estimated daily phthalate exposures in a population of mothers of male infants exhibiting reduced anogenital distance. Environ Health Perspect 114 (2006) 805-809
69. McEwen B., Akama K., Alves S., Brake W.G., Bulloch K., Lee S., et al. Tracking the estrogen receptor in neurons: implications for estrogen-induced synapse formation. Proc Natl Acad Sci USA 98 (2001) 7093-7100
70. Melcangi R.C., and Panzica G.C. Neuroactive steroids: old players in a new game. Neuroscience 138 (2006) 733-739
71. Moffat S.D., Zonderman A.B., Metter E.J., Blackman M.R., Harman S.M., and Resnick S.M. Longitudinal assessment of serum free testosterone concentration predicts memory performance and cognitive status in elderly men. J Clin Endocrinol Metab 87 (2002) 5001-5007
72. Moffat S.D., Zonderman A.B., Metter E.J., Kawas C., Blackman M.R., Harman S.M., et al. Free testosterone and risk for Alzheimer disease in older men. Neurology 62 (2004) 188-193
73. Mukai H., Takata N., Ishii H.T., Tanabe N., Hojo Y., Furukawa A., et al. Hippocampal synthesis of estrogens and androgens which are paracrine modulators of synaptic plasticity: synaptocrinology. Neuroscience 138 (2006) 757-764
74. Munte T.F., Altenmuller E., and Jancke L. The musician's brain as a model of neuroplasticity. Nat Rev Neurosci 3 (2002) 473-478
75. Nottebohm F. Neuronal replacement in adult brain. Brain Res Bull 57 (2002) 737-749
76. Olmos G., Naftolin F., Perez J., Tranque P.A., and Garcia-Segura L.M. Synaptic remodeling in the rat arcuate nucleus during the estrous cycle. Neuroscience 32 (1989) 663-667
77. Pan G., Hanaoka T., Yoshimura M., Zhang S., Wang P., Tsukino H., et al. Decreased serum free testosterone in workers exposed to high levels of di-n-butyl phthalate (DBP) and di-2-ethylhexyl phthalate (DEHP): a cross-sectional study in china. Environ Health Perspect 114 (2006) 1643-1648
78. Parducz A., Hajszan T., Maclusky N.J., Hoyk Z., Csakvari E., Kurunczi A., et al. Synaptic remodeling induced by gonadal hormones: neuronal plasticity as a mediator of neuroendocrine and behavioral responses to steroids. Neuroscience 138 (2006) 977-985
79. Peters A., Sethares C., and Moss M.B. The effects of aging on layer 1 in area 46 of prefrontal cortex in the rhesus monkey. Cereb Cortex 8 (1998) 671-684
80. Phillips S.M., and Sherwin B.B. Effects of estrogen on memory function in surgically menopausal women. Psychoneuroendocrinology 17 (1992) 485-495
81. Rajapakse N., Silva E., Scholze M., and Kortenkamp A. Deviation from additivity with estrogenic mixtures containing 4-nonylphenol and 4-tert-octylphenol detected in the E-SCREEN assay. Environ Sci Technol 38 (2004) 6343-6352
82. Rapp P.R., Morrison J.H., and Roberts J.A. Cyclic estrogen replacement improves cognitive function in aged ovariectomized rhesus monkeys. J Neurosci 23 (2003) 5708-5714
83. Schantz S.L., and Widholm J.J. Cognitive effects of endocrine-disrupting chemicals in animals. Environ Health Perspect 109 (2001) 1197-1206
84. Schumacher M., Weill-Engerer S., Liere P., Robert F., Franklin R.J., Garcia-Segura L.M., et al. Steroid hormones and neurosteroids in normal and pathological aging of the nervous system. Prog Neurobiol 71 (2003) 3-29
85. Sherwin B.B. Estrogen and cognitive aging in women. Neuroscience 138 (2006) 1021-1026
86. Shumaker S.A., et al. Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: women's health initiative memory study. JAMA 291 (2004) 2947-2958
87. Swan S.H. Does our environment affect our fertility? Some examples to help reframe the question. Semin Reprod Med 24 (2006) 142-146
88. Swan S.H., et al. Decrease in anogenital distance among male infants with prenatal phthalate exposure. Environ Health Perspect 113 (2005) 1056-1061
89. Tanapat P., Hastings N.B., and Gould E. Ovarian steroids influence cell proliferation in the dentate gyrus of the adult female rat in a dose- and time-dependent manner. J Comp Neurol 481 (2005) 252-265
90. Tang Y., Janssen W.G., Hao J., Roberts J.A., McKay H., Lasley B., et al. Estrogen replacement increases spinophilin-immunoreactive spine number in the prefrontal cortex of female rhesus monkeys. Cereb Cortex 14 (2004) 215-223
91. Taupin P. Consideration of adult neurogenesis from basic science to therapy. Med Sci Monit 11 (2005) LE16-LE17
92. Taupin P. Adult neurogenesis in mammals. Curr Opin Mol Ther 8 (2006) 345-351
93. Travison T.G., Araujo A.B., O'donnell A.B., Kupelian V., and McKinlay J.B. A population-level decline in serum testosterone levels in American men. J Clin Endocrinol Metab 92 (2007) 196-202
94. Van Kampen J.M., and Robertson H.A. A possible role for dopamine D3 receptor stimulation in the induction of neurogenesis in the adult rat substantia nigra. Neuroscience 136 (2005) 381-386
95. van Praag H., Shubert T., Zhao C., and Gage F.H. Exercise enhances learning and hippocampal neurogenesis in aged mice. J Neurosci 25 (2005) 8680-8685
96. Weiss B. Vulnerability to pesticide neurotoxicity is a lifetime issue. Neurotoxicology 21 (2000) 67-73
97. Weiss B. Sexually dimorphic nonreproductive behaviors as indicators of endocrine disruption. Environ Health Perspect 110 Suppl 3 (2002) 387-391
98. Weiss B., Clarkson T.W., and Simon W. Silent latency periods in methylmercury poisoning and in neurodegenerative disease. Environ Health Perspect 110 Suppl 5 (2002) 851-854
99. Welshons W.V., Nagel S.C., and vom Saal F.S. Large effects from small exposures. III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure. Endocrinology 147 (2006) S56-S69
100. Woolley C.S., and McEwen B.S. Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat. J Neurosci 12 (1992) 2549-2554
101. Woolley C.S., Gould E., Frankfurt M., and McEwen B.S. Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons. J Neurosci 10 (1990) 4035-4039
102. Yaffe K. Hormone therapy and the brain: Deja vu all over again?. JAMA 289 (2003) 2717-2719
103. Yaffe K., Lui L.Y., Zmuda J., and Cauley J. Sex hormones and cognitive function in older men. J Am Geriatr Soc 50 (2002) 707-712
104. Yoshimi K., Ren Y.R., Seki T., Yamada M., Ooizumi H., Onodera M., et al. Possibility for neurogenesis in substantia nigra of parkinsonian brain. Ann Neurol 58 (2005) 31-40
105. Zandi P.P., et al. Hormone replacement therapy and incidence of Alzheimer disease in older women: the cache county study. JAMA 288 (2002) 2123-2129
106. Zhao L., and Brinton R.D. Select estrogens within the complex formulation of conjugated equine estrogens (premarin) are protective against neurodegenerative insults: implications for a composition of estrogen therapy to promote neuronal function and prevent Alzheimer's disease. BMC Neurosci 7 (2006) 24
107. Zhao M., Momma S., Delfani K., Carlen M., Cassidy R.M., Johansson C.B., et al. Evidence for neurogenesis in the adult mammalian substantia nigra. Proc Natl Acad Sci USA 100 (2003) 7925-7930