Effect of long-term vagal stimulation on food intake and body weight during diet induced obesity in rats

Journal of Physiology and Pharmacology

Volumn 58, Issue SUPPL. 1, 2007, Pages 5-12

  Bugajski, Andrzej J ^a   Gil, K ^a   Ziomber, A ^a   Zurowski, D ^a   Zaraska, W ^b   Thor, P J ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b Department of Micro and Nanotechnology of Wide Bandgap Semiconductors   (Poland)

Author keywords

Body weight; Fat pad; Food intake; Microchip; Obesity; Vagal nerve stimulation

Indexed keywords

ANIMAL EXPERIMENT; BODY WEIGHT; CHEMORECEPTOR; CONFERENCE PAPER; CONTROLLED STUDY; DIET; FEEDING BEHAVIOR; FOOD INTAKE; GLUCOSE METABOLISM; MALE; MECHANORECEPTOR; NONHUMAN; OBESITY; RAT; VAGUS NERVE; VAGUS NERVE STIMULATION; WEIGHT GAIN;

ADIPOSE TISSUE; AFFERENT PATHWAYS; ANIMALS; APPETITE; BODY WEIGHT; DIETARY FATS; EATING; ELECTRIC STIMULATION; EPIDIDYMIS; FEEDING BEHAVIOR; MALE; OBESITY; RATS; RATS, WISTAR; VAGUS NERVE; WEIGHT GAIN; WEIGHT LOSS;

EID: 34948835571     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (42)

1. Schwartz MW, Woods SC, Porte D, Seeley RJ, Baskin DG. Central nervous system control of food intake. Nature 2000; 404: 661-671.
2. Schwartz GJ. The Role of gastrointestinal vagal afferents in the control of food intake: Current prospects. Nutrition 2000; 16: 866-873.
3. Berthoud HR. Multiple neural systems controlling food intake and body weight. Neurosci Biobehav Rev 2002; 26(4): 393-428.
4. Cummings DE, Overduin J. Gastrointestinal regulation of food intake. J Clin Invest 2007; 117(1): 13-23.
5. Morton GJ, Cummings DE, Baskin DG, Barsh GS, Schwartz MW. Central nervous system control of food intake and body weight. Nature 2006; 443: 289-295.
6. Havel PJ. Peripheral signals conveying metabolic information to the brain: short-term and long-term regulation of food intake and energy homeostasis. Exp Biol Med 2001; 226: 963-977.
7. Mayer J. Glucostatic mechanism of regulation of ford intake. N Engl J Med 1953; 249: 13-16.
8. Thompson DA, Campbell RG. Hunger in humans induced by 2-deoxy-D-glucose: glucoprivic control of taste preference and food intake. Science 1977; 198: 1065-1068.
9. Campfield LA, Smith FJ. Transient declines in blood glucose signal meal initiation. Int J Obes 1990; 14: 15-31.
10. Campfield LA, Smith FJ, Rosenbaum M. Human hunger: is there a role for blood glucose dynamics? Appetite 1992; 18: 244.
11. Królczyk G, Żurowski D, Sobocki J, et al. Effects of continuous microchip (MC) vagal neuromodulation on gastrointestinal function in rats. J Physiol Pharmacol 2001; 52(4Pt 1): 705-715.
12. Laskiewicz J, Królczyk G, Żurowski D, Sobocki J, Matyja A, Thor PJ. Effects of vagal neuromodulation and vagotomy on control of food intake and body weight in rats. J Physiol Pharmacol 2003; 54(4): 603-610.
13. Laskiewicz J, Królczyk G, Żurowski D, Enck P, Thor PJ. Capsaicin induced deafferentation enhances the effect of electrical vagal nerve stimulation on food intake and body mass. J Physiol Pharmacol 2004; 55 (1 Pt 2): 155-163.
14. Randich A, Tyler WJ, Cox JE, Meller ST, Kelm GR, Bharaj SS. Responses of celiac and cervical vagal afferents to infusions of lipids in the jejunum or ileum of the rat. Am J Physiol Regul Integr Comp Physiol 2000; 278: R34-R43.
15. Cox JE, William J. Tyler WJ, Randich A, et al. Suppression of food intake, body weight, and body fat by jejunal fatty acid infusions. Am J Physiol Regul Integr Comp Physiol 2000; 278: R604-R610.
16. Cox JE, Kelm GR, Meller ST, Randich A. Suppression of food intake by GI fatty acid infusions: roles of celiac vagal afferents and cholecystokinin. Physiol Behav 2004; 82(1): 27-33.
17. Smith GP, Jerome C, Norgren R. Afferent axons in abdominal vagus mediates satiety effect of cholecystokinin in rats. Am J Physiol Regul Integr Comp Physiol 1985; 249: R638-R641.
18. Smith GP, Jerome C, Cushin BJ, Eterno R, Simansky KJ. Abdominal vagotomy blocks the satiety effect of cholecystokinin in the rat. Science 1981; 213: (4511): 1036-1037.
19. Moran TH, Baldessarini AR, Salorio CF, Lowery T, Schwartz GJ. Vagal afferent and efferent contributions to the inhibition of food intake by cholecystokinin. Am J Physiol Regul Integr Comp Physiol 1997; 272: R1245-R1251.
20. Peters JH, Simasko SM, Ritter RC. Modulation of vagal afferent excitation and reduction of food intake by leptin and cholecystokinin. Physiol Behav 2006; 89(4): 477-485.
21. Peters JH, Karpiel AB, Ritter RC, Simasko SM. Cooperative activation of cultured vagal afferent neurons by leptin and cholecystokinin. Endocrinology 2004; 145(8): 3652-3857.
22. Niijima A. Reflex effects from leptin sensors in the white adipose tissue of the epididymis to the efferent activity of the sympathetic and vagus nerve in the rat. Neurosci Lett 1999; 262(2): 125-128.
23. Williams DL, Grill HJ, Cummings DE, Kaplan JM. Vagotomy dissociates short- and long-term controls of circulating ghrelin. Endocrinology 2003; 144(12): 5184-5187.
24. Date Y, Toshinai K, Koda S, et al. Peripheral interaction of ghrelin with cholecystokinin on feeding regulation. Endocrinology 2005; 146(8): 3518-3525.
25. Woods SC, D'Alessio DA, Tso P, et al. Consumption of a high-fat diet alters the homeostatic regulation of energy balance. Physiol Behav 2004; 83: 573-578.
26. Berthoud HR, Neuhuber WL. Functional and chemical anatomy of the afferent vagal system. Autonom Neurosci Basic Clin 2000; 85: 1-17.
27. Powley TL, Phillips RJ. Musings on the wanderer: what's new in our understanding of vagovagal reflexes? I. Morphology and topography of vagal afferents innervating the GI tract. Am J Physiol Gastrointest Liver Physiol 2002; 283(6): G1217-G1225.
28. Furness JB, Koopmans HS, Robbins HL, Clerc N, Tobin JM, Morris MJ. Effects of vagal and splanchnic section on food intake, weight, serum leptin and hypothalamic neuropeptide Y in rat. Autonom Neurosci Basic Clin 2001; 92: 28-36.
29. Sackeim HA, Rush J, George MS, at al. Vagus nerve stimulation (VNS™) for treatment-resistant depression: efficacy, side effects, and predictors of outcome. Neuropsychopharmacology 2001; 25: 713-728.
30. Koren MS, Holmes MD. Vagus nerve stimulation does not lead to significant changes in body weight in patients with epilepsy. Epilepsy & Behavior 2006; 8: 246-249.
31. Roslin M, Kurian M. The use of electrical stimulation of the vagus nerve to treat morbid obesity. Epilepsy & Behavior 2001; 2: S11-S16.
32. Burneo JG, Faught E, Knowlton R, Morawetz R, Kuzniecky R. Weight loss associated with vagus nerve stimulation. Neurology 2002; 59(3): 463-464.
33. Walls EK, Phillips RJ, Wang FB, Holst MC, Powley TL. Suppression of meal size by intestinal nutrients is eliminated by celiac vagal deafferentation. Am J Physiol 1995; 269: R1410-R1419.
34. Stubbs J, Ferres S, Horgan G. Energy density of foods: effects on energy intake. Crit Rev Food Sci Nutr 2000; 40: 481-515.
35. Eisen EJ, Leatherwood, JM. Predicting percent fat in mice. Growth 1981; 45(2): 100-107.
36. Rogers P, Webb GP. Estimation of body fat in normal and obese mice. Br J Nutr 1980; 43: 83-86.
37. Lavau M, Bazin R. Inguinal fat pad weight plotted versus body weight as a method of genotype identification in 16-day-old Zucker rats. J Lipid Res 1982; 23(6): 941-943.
38. Bartness TJ. Dual innervation of white adipose tissue: some evidence for parasympathetic nervous system involvement. J Clin Invest 2002; 110(9): 1235-1237.
39. Bartness TJ, Bamshad M. Innervation of mammalian white adipose tissue: implications for the regulation of total body fat. Am J Physiol 1998; 275(5 Pt 2): R1399-R1411.
40. Kreier F, Fliers E, Voshol PJ, et al. Selective parasympathetic innervation of subcutaneous and intra-abdominal fat - functional implications. J Clin Invest 2002; 110(9): 1243-1250.
41. Giordano A, Song CK, Bowers RR, et al. White adipose tissue lacks significant vagal innervation and immunohistochemical evidence of parasympathetic innervation. Am J Physiol Regul Integr Comp Physiol 2006; 291(5): R1243-R1255.
42. Powley TL, Chi MM, Schier LA, Phillips RJ. Obesity: should treatments target visceral afferents? Physiol Behav 2005; 86: 698-708.