Capsaicin induced deafferentation enhances the effect of electrical vagal nerve stimulation on food intake and body mass

Journal of Physiology and Pharmacology

Volumn 55, Issue 1 II, 2004, Pages 155-163

  Laskiewicz, J ^a   Krolczyk G ^a   Zurowski, D ^a   Enck, P ^b   Thor, Piotr J ^a,c  

^a JAGIELLONIAN UNIVERSITY   (Poland)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

Body weight; Capsaicin; Food intake; Leptin; Vagal stimulation

Indexed keywords

CAPSAICIN; GLUCOSE; LEPTIN; INSULIN;

ANIMAL EXPERIMENT; ARTICLE; BODY MASS; BODY WEIGHT; CONTROLLED STUDY; DEAFFERENTATION; DOWN REGULATION; ELECTROSTIMULATION; FOOD INTAKE; MALE; NERVE STIMULATION; NEUROMODULATION; NONHUMAN; RAT; SATIETY; SENSORY NERVE; VAGUS NERVE; ANIMAL; BLOOD; CHEMISTRY; COMPARATIVE STUDY; DENERVATION; DIET RESTRICTION; DRUG EFFECT; EATING; EVALUATION; GLUCOSE BLOOD LEVEL; INJURY; METABOLISM; METHODOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TOPICAL DRUG ADMINISTRATION; WISTAR RAT;

ADMINISTRATION, TOPICAL; AFFERENT PATHWAYS; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CAPSAICIN; DENERVATION; DOWN-REGULATION; EATING; ELECTRIC STIMULATION; FASTING; INSULIN; LEPTIN; MALE; MICROCHEMISTRY; RATS; RATS, WISTAR; VAGUS NERVE;

EID: 16544380993     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Lutz TA, Althus J, Rossi R, Scharrer E. Anorectic effect is not transmitted by capsaicin-sensitive nerve fibers. Am J Physiol 1998; 274(6pt2): R1777-1782.
2. Sobocki J, Thor PJ, Krolczyk G, Uson J, Diaz-Guemes I, Lipinski M. The cybergut. An experimental study on permanent microchip neuromodulation for control of gut function. Acta Chir Belg 2002; 102: 11-13.
3. Parker APJ, Polkey CE, Binne CD, Madigan C, Ferrie CD, Robinson R. Vagal nerve stimulation in epileptic encephalopathies. Pediatrics 1999; 103(4): 788-792.
4. Thor PJ, Sobocki J. Neuromodulation of vago-vagal reflex. Przegl Lek 2000; 57(Suppl 5): 79-81.
5. Schwartz GJ. The role of gastrointestinal vagal afferents in the control of food intake: current prospects. Nutrition 2000; 16(10): 866-873.
6. South EH, Ritter RC. Capsaicin application to central or peripheral vagal fibers attenuates CCK satiety. Peptides 1988; 9(3): 601-612.
7. Chavez M, Kelly L, York DA, Berthound HR. Chemical lesion of visceral afferents causes overconsumption of unfamiliar high-fet diets in rats. Am J Physiol 1997; 272(5pt2): R1657-1663.
8. Falchi M, Ferrara F, Gharib C, Dib B. Intracerebroventricular capsaicin and food intake in the rat. Drugs Exp Clin Res 2001; 27(2): 61-67.
9. Schwartz GJ, Moran TH. Duodenal nutrient exposure elicits nutrient-specific gut motility and vagal afferent signals in rat. Am J Physiol 1998; 274: 1236-1242.
10. Mei N. Intestinal chemosensitivity. In: Advances in the Innervation of the Gastrointestinal Tract, GE Holle, JD Wood (eds). Amsterdam, Elsevier, 1992, pp.271-281.
11. Krolczyk G, Zurowski D, Sobocki J et al. Effects of continuous microchip (MC) vagal neuromodulation on gastrointestinal function in rats. J Physiol Pharmacol 2001; 42(4pt1); 705-715.
12. Jaworek J, Bonior J, Pierzchalski P et al. Leptin protects the pancreas from damage induced by caerulein overstimulation by modulating cytokine production. Pancreatology 2002; 2(2): 89-99.
13. Forster J, Sarosiek I, Delcore R, Lin Z, Raju GS, McCallum RW. Gastric pacing is a new surgical treatment for gastroparesis. Am J Surg 2001; 182(6): 676-681.
14. Cigaina V, Saggioro A, Rigo V, Pinato GP, Ischia S. Long -term effects of gastric pacing to reduce feed intake in swine. Obes Surg 1996; 6(3): 250-253.
15. Sobocki J, Thor PJ, Usson J, Dias-Guemes I, Calles C, Pascual S. Microchip vagal pacing reduces food intake and body mass. Hepatogastroenterology 2001; 48/42: 1783-1787.
16. Yox DP, Ritter RC. Capsaicin attenuates suppression of sham feeding induced by intestinal nutrients. Am J Physiol 1988; 255(4 Pt 2): R569-R574.
17. Tamura CS, Ritter RC. Intestinal capsaicin transiently attenuates suppression of sham feeding by oleate. Am J Physiol 1994; 267(2 Pt 2): R561-568.
18. Roth HS, Ingram DK, Lane MA. Caloric restriction in primates and relevance to humans. Ann NY Acad Sci 2001; 928: 305-315.
19. Gidda JS, Goyal RK. Influence of successive vagal stimulations on contractions in esophageal smooth muscle of opossum. J Clin Invest 1993; 71(5): 1095-1103.
20. Hellstrom PM, Naslund E. Interaction between gastric emptying and satiety, with special reference to glucagon-like peptide. Physiol Behav 2001; 74(4-5): 735-741.
21. Blackshaw LA, Page AJ, Partosoedarso ER. Acute effects of capsaicin on gastrointestinal vagal afferents. Neuroscience 2000; 96(2): 407-416.
22. Krolczyk G, Zurowski D, Thor PJ. Interstitial cells of Cajal and their pacemaker function. Folia Med Cracov 2001; 42(1-2): 45-51.
23. Chang TM, Thagesen H, Lee KY, Roth FL, Chey WY. Canine vagus nerve stores cholecystokinin-58 and -8 but releases only cholecystokinin-8 upon electrical vagal stimulation. Regul Pept 2000; 87(1-3): 1-7.
24. Krolczyk G, Sobocki J, Laskiewicz J, Thor PJ. Electrical neuromodulation of vagal activity inhibits gastric motility in rats. XXII Congress of the Polish Physiological Society. J Physiol Pharmacol 2002; 53 (suppl. 1): 50.
25. Takahashi T, Owyang C. Mechanism of cholecystokinin-induced relaxation of the rat stomach. J Auton Nerv Syst 1999; 75(2-3): 123-130.