Using classification structure pharmacokinetic relationship (SCPR) method to predict drug bioavailability based on grid-search support vector machine

Analytica Chimica Acta

Volumn 601, Issue 2, 2007, Pages 156-163

  Wang, Jie ^a   Du, Hongying ^a   Yao, Xiaojun ^a   Hu, Zhide ^a  

^a LANZHOU UNIVERSITY   (China)

Author keywords

Bioavailability; Classification structure pharmacokinetic relationship; Grid search support vector machine; Linear discriminant analysis

Indexed keywords

DISCRIMINANT ANALYSIS; MATHEMATICAL MODELS; MOLECULAR STRUCTURE; PHARMACOKINETICS; SUPPORT VECTOR MACHINES;

DRUG BIOAVAILABILITY; GRID-SEARCH SUPPORT VECTOR MACHINE; MOLECULAR DESCRIPTORS; NONLINEAR MODELS;

DRUG PRODUCTS;

ACETYLSALICYLIC ACID; ACICLOVIR; ALENDRONIC ACID; ALLOPURINOL; AMANTADINE; AMILORIDE; AMINOGLUTETHIMIDE; AMIODARONE; AMITRIPTYLINE; AMLODIPINE; AMOXICILLIN; AMPICILLIN; ATENOLOL; ATORVASTATIN; ATROPINE; AZATHIOPRINE; BACLOFEN; BENDROFLUMETHIAZIDE; BETAMETHASONE; BROMOCRIPTINE; BUMETANIDE; CAPTOPRIL; CARBAMAZEPINE; CEFALEXIN; CHLORAMPHENICOL; CHLORDIAZEPOXIDE; CHLOROTHIAZIDE; CHLORTALIDONE; PARACETAMOL; UNINDEXED DRUG;

ARTICLE; COMPUTER PROGRAM; DRUG BIOAVAILABILITY; DRUG STRUCTURE; PREDICTION; PRIORITY JOURNAL; STATISTICAL MODEL; STRUCTURE ACTIVITY RELATION; SUPPORT VECTOR MACHINE;

BIOLOGICAL AVAILABILITY; DISCRIMINANT ANALYSIS; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS;

EID: 34848926240     PISSN: 00032670     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aca.2007.08.040     Document Type: Article

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