Effect of supplemental dietary zinc on the mammalian target of rapamycin (mTOR) signaling pathway in skeletal muscle and liver from post-absorptive mice

Biological Trace Element Research

Volumn 118, Issue 1, 2007, Pages 65-76

  McClung, James P ^a   Tarr, Tyson N ^a   Barnes, Brian R ^a   Scrimgeour, Angus G ^a   Young, Andrew J ^a  

^a U S ARMY RESEARCH INSTITUTE OF ENVIRONMENTAL MEDICINE   (United States)

Author keywords

Mice; mTOR; Multiplex analysis; Translation initiation; Zinc

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PROTEIN KINASE B; S6 KINASE; ZINC;

ABSORPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; COMPARATIVE STUDY; CONTROLLED STUDY; DIET RESTRICTION; DIET SUPPLEMENTATION; DIETARY INTAKE; IN VIVO STUDY; INSULIN BLOOD LEVEL; LIVER METABOLISM; MALE; MOUSE; MUSCLE METABOLISM; NONHUMAN; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REFEEDING; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; STATISTICAL SIGNIFICANCE; TREATMENT DURATION; WESTERN BLOTTING;

ANIMALS; DIETARY SUPPLEMENTS; GLYCOGEN SYNTHASE KINASE 3; INSULIN; LIVER; MALE; MICE; MICE, INBRED C57BL; MUSCLE, SKELETAL; PHOSPHORYLATION; PROTEIN KINASES; RIBOSOMAL PROTEIN S6 KINASES; SIGNAL TRANSDUCTION; ZINC;

ANIMALIA; MAMMALIA; MUS;

EID: 34848893364     PISSN: 01634984     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12011-007-0018-8     Document Type: Article

References (31)

1. Vallee BL, Falchuk KH (1993) The biochemical basis of zinc physiology. Phys Rev 73:79-118
2. Huang JS, Mukherjee JJ, Chung T, Crilly KS, Kiss Z (1999) Extracellular calcium stimulates DNA synthesis in synergism with zinc, insulin, and insulin-like growth factor I in fibroblasts. Eur J Biochem 266:943-951
3. Tang XH, Shay NF (2001) Zinc has an insulin-like effect on glucose transport mediated by phosphoinosotol-3-kinase and Akt in 3T3-L1 fibroblasts and adipocytes. J Nutr 131:1414-1420
4. Haase H, Maret W (2005) Protein tyrosine phosphatases as targets of the combined insulinomimetic effects of zinc and oxidants. BioMetals 18:333-338
5. Thomas G, Hall MN (1997) TOR signaling and control of cell growth. Curr Opin Cell Biol 9:782-787
6. Kleijn M, Scheper GC, Voorma HO, Thomas AA (1998) Regulation of translation initiation factors by signal transduction. Eur J Biochem 253:531-544
7. Kimball SR, Shantz LM, Horetsky RL, Jefferson LS (1999) Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6. J Biol Chem 274:11647-11652
8. Hay N, Sonenberg N (2004) Upstream and downstream of mTOR. Genes Dev 18:1926-1945
9. Crozier SJ, Kimball SR, Emmert SW, Anthony JC, Jefferson LS (2005) Oral leucine administration stimulates protein synthesis in rat skeletal muscle. J Nutr 135:376-382
10. Kim S, Jung Y, Kim D, Koh H, Chung J (2000) Extracellular zinc activates p70 S6 kinase through the phosphatidylinositol 3-kinase signaling pathway. J Biol Chem 275:25979-25984
11. Lynch CJ, Patson BJ, Goodman SA, Trapolsi D, Kimball SR (2001) Zinc stimulates the activity of the insulin- and nutrient regulated protein kinase mTOR. Am J Physiol Endocrinol Metab 281:E25-E34
12. Reeves PG, Nielson FH, Fahey GC Jr (1993) AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 123:1939-1951
13. McClung JP, Stahl CH, Marchitelli LJ, Morales-Martinez N, Mackin KM, Young AJ, Scrimgeour AG (2006) Effects of dietary phytase on body weight gain, body composition and bone strength in rats fed a low-zinc diet. J Nutr Biochem 17:190-196
14. Yoshizawa F, Endo M, Ide H, Yagasaki K, Funabiki R (1995) Translational regulation of protein synthesis in the liver and skeletal muscle of mice in response to refeeding. J Nutr Biochem 6:130-136
15. Kimball SR, Jefferson LS, Nguyen HV, Suryawan A, Busk JA, Davis TA (2000) Feeding stimulates protein synthesis in muscle and liver of neonatal pigs through an mTOR-dependent process. Am J Physiol Endocrinol Metab 279:E1080-E1087
16. Yoshizawa F, Kimball SR, Vary TC, Jefferson LS (1998) Effect of dietary protein on translation initiation in rat skeletal muscle and liver. Am J Physiol Endocrinol Metab 275:E814-E820
17. Reiter AK, Crozier SJ, Kimball SR, Jefferson LS (2005) Meal feeding alters translational control of gene expression in rat liver. J Nutr 135:367-375
18. Bolster DR, Kubica N, Crozier SJ, Williamson DL, Farrell PA, Kimball SR, Jefferson LS (2003) Immediate response of mammalian target of rapamycin (mTOR)-mediated signaling following acute resistance exercise in rat skeletal muscle. J Physiol 553:213-220
19. Parkington JD, Siebert AP, Lebrasseur NK, Fielding RA (2003) Differential activation of mTOR signaling by contractile activity in skeletal muscle. Am J Physiol Regul Integr Comp Physiol 285:R1086-R1090
20. S6K, and ERK 1/2 phosphorylation in aged skeletal muscle. J Appl Physiol 97:243-248
21. Pelech S (2004) Tracking cell signaling protein expression and phosphorylation by innovative proteomic solutions. Curr Pharm Biotechnol 5:69-77
22. Khan IH, Mendoza S, Rhyne P, Ziman M, Tuscano J, Eisenger D, Kung H-J, Luciw PA (2006) Multiplex analysis of intracellular signaling pathways in lymphoid cells by microbead suspension arrays. Mol Cell Proteomics 5:758-768
23. Kofoed K, Schneider UV, Scheel T, Andersen O, Eugen-Olsen J (2006) Development and validation of a multiplex add-on assay for sepsis biomarkers using xMAP technology. Clin Chem 52:1284-1293
24. Lash GE, Scaife PJ, Innes BA, Otun HA, Robson SC, Searle RF, Bulmer JN (2006) Comparison of three multiplex cytokine analysis systems: luminex, searchlight and FAST quant. J Immunol Methods 309:205-208
25. Flagella M, Bui S, Zheng Z, Nguyen CT, Zhang A, Pastor L, Ma Y, Yang W, Crawford KL, McMaster GK, Witney F, Luo Y (2006) A multiplex branched DNA assay for parallel quantitative gene expression profiling. Anal Biochem 352:50-60
26. Liu MY, Xydakis AM, Hoogeveen RC, Jones PH, Smith EO, Nelson KW, Ballantyne CM (2005) Multiplexed analysis of biomarkers related to obesity and the metabolic syndrome in human plasma, using the Luminex-100 system. Clin Chem 51:1102-1109
27. Patel S, Doble B, Woodgett JR (2004) Glycogen synthase kinase-3 in insulin and Wnt signaling: a double edged sword? Biochem Soc Trans 32:803-808
28. Gomot MJ, Faure P, Roussel AM, Coudray C, Osman M, Favier A (1992) Effect of acute zinc deficiency on insulin receptor binding in rat adipocytes. Biol Trace Elem Res 32:331-335
29. 2+. Biochem Mol Biol Int 34:1177-1187
30. Li J, Elberg G, Sekar N, bin He Z, Shechter Y (1997) Antilipolytic actions of vanadate and insulin in rat adipocytes mediated by distinctly different mechanisms. Endocrinology 138:2274-2279
31. Samet JM, Silbajoris R, Wu W, Graves LM (1999) Tyrosine phosphatases as targets in metal-induced signaling in human airway epithelial cells. Am J Respir Cell Mol Biol 21:357-364