메뉴 건너뛰기




Volumn 186, Issue , 2002, Pages S40-S46

Valacyclovir for herpes simplex virus infection: Long-term safety and sustained efficacy after 20 years’ experience with acyclovir

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; PLACEBO; VALACICLOVIR;

EID: 0037108422     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/342966     Document Type: Article
Times cited : (145)

References (43)
  • 1
    • 0023767079 scopus 로고
    • Prolonged continuous versus intermittent oral acyclovir treatment in normal adults with frequently recurring genital herpes simplex virus infection
    • Mertz GJ, Eron L, Kaufman R, et al. Prolonged continuous versus intermittent oral acyclovir treatment in normal adults with frequently recurring genital herpes simplex virus infection. Am J Med 1988;85:14-9.
    • (1988) Am J Med , vol.85 , pp. 14-19
    • Mertz, G.J.1    Eron, L.2    Kaufman, R.3
  • 2
    • 0000758166 scopus 로고
    • Nine-year effectiveness of continuous suppressive therapy with aciclovir in patients with recurrent genital herpes
    • Program and abstracts of the Congress of the European Academy of Dermatology and Venereology (Brussels)
    • Baker DA, Safrin S, Deeter RG, Walker A, Barton G, and the Aciclovir Study Group. Nine-year effectiveness of continuous suppressive therapy with aciclovir in patients with recurrent genital herpes [abstract P220]. In: Program and abstracts of the Congress of the European Academy of Dermatology and Venereology (Brussels). J Eur Acad Dermatol Venereol 1995;5(Suppl 1):S169.
    • (1995) J Eur Acad Dermatol Venereol , vol.5 , pp. S169
    • Baker, D.A.1    Safrin, S.2    Deeter, R.G.3    Walker, A.4    Barton, G.5
  • 3
    • 0030910966 scopus 로고    scopus 로고
    • Treatment of herpes simplex gingivostomatitis with aciclovir in children-a randomised double blind placebo controlled study
    • Amir J, Harel L, Smetana Z, Varsano I. Treatment of herpes simplex gingivostomatitis with aciclovir in children-a randomised double blind placebo controlled study. BMJ 1997;314:1800-3.
    • (1997) BMJ , vol.314 , pp. 1800-1803
    • Amir, J.1    Harel, L.2    Smetana, Z.3    Varsano, I.4
  • 5
    • 0026410702 scopus 로고
    • A controlled trial of acyclovir for chickenpox in normal children
    • Dunkle LM, Arvin AM, Whitley RJ, et al. A controlled trial of acyclovir for chickenpox in normal children. N Engl J Med 1991;325:1539-44.
    • (1991) N Engl J Med , vol.325 , pp. 1539-1544
    • Dunkle, L.M.1    Arvin, A.M.2    Whitley, R.J.3
  • 6
    • 9044244911 scopus 로고    scopus 로고
    • Administration of oral acyclovir suppressive therapy after neonatal herpes simplex virus disease limited to the skin, eyes and mouth: Results of a phase I/II trial
    • Kimberlin D, Powell D, Gruber W, et al. Administration of oral acyclovir suppressive therapy after neonatal herpes simplex virus disease limited to the skin, eyes and mouth: results of a phase I/II trial. Pediatr Infect Dis J 1996;15:247-54.
    • (1996) Pediatr Infect Dis J , vol.15 , pp. 247-254
    • Kimberlin, D.1    Powell, D.2    Gruber, W.3
  • 7
    • 0033980349 scopus 로고    scopus 로고
    • Monitoring pregnancy outcomes after prenatal drug exposure through prospective pregnancy registries: A pharmaceutical company commitment
    • Reiff-Eldridge R, Heffner CR, Ephross SA, et al. Monitoring pregnancy outcomes after prenatal drug exposure through prospective pregnancy registries: a pharmaceutical company commitment. Am J Obstet Gynecol 2000;182:159-63.
    • (2000) Am J Obstet Gynecol , vol.182 , pp. 159-163
    • Reiff-Eldridge, R.1    Heffner, C.R.2    Ephross, S.A.3
  • 8
    • 0030025092 scopus 로고    scopus 로고
    • Acyclovir suppression to prevent cesarean delivery after first-episode genital herpes
    • Scott LL, Sanchez PJ, Jackson GL, Zeray F, Wendel GD. Acyclovir suppression to prevent cesarean delivery after first-episode genital herpes. Obstet Gynecol 1996;87:69-73.
    • (1996) Obstet Gynecol , vol.87 , pp. 69-73
    • Scott, L.L.1    Sanchez, P.J.2    Jackson, G.L.3    Zeray, F.4    Wendel, G.D.5
  • 9
    • 0025044734 scopus 로고
    • Acyclovir in late pregnancy to prevent neonatal herpes simplex
    • Stray-Pedersen B. Acyclovir in late pregnancy to prevent neonatal herpes simplex. Lancet 1990;336:756.
    • (1990) Lancet , vol.336 , pp. 756
    • Stray-Pedersen, B.1
  • 10
    • 0031940576 scopus 로고    scopus 로고
    • A randomised placebo controlled trial of suppressive acyclovir in late pregnancy in women with recurrent genital herpes infection
    • Brocklehurst P, Kinghorn G, Carney O, et al. A randomised placebo controlled trial of suppressive acyclovir in late pregnancy in women with recurrent genital herpes infection. Br J Obstet Gynaecol 1998;105:275-80.
    • (1998) Br J Obstet Gynaecol , vol.105 , pp. 275-280
    • Brocklehurst, P.1    Kinghorn, G.2    Carney, O.3
  • 12
    • 0023858568 scopus 로고
    • Use of acyclovir to treat chickenpox in pregnancy
    • Boyd K, Walker E. Use of acyclovir to treat chickenpox in pregnancy. BMJ 1988;296:393-4.
    • (1988) BMJ , vol.296 , pp. 393-394
    • Boyd, K.1    Walker, E.2
  • 13
    • 0021089633 scopus 로고
    • Pharmacokinetics of acyclovir after intravenous and oral administration
    • De Miranda P, Blum MR. Pharmacokinetics of acyclovir after intravenous and oral administration. J Antimicrob Chemother 1983;12(Suppl B):29-37.
    • (1983) J Antimicrob Chemother , vol.12 , pp. 29-37
    • De Miranda, P.1    Blum, M.R.2
  • 14
    • 0027768955 scopus 로고
    • Pharmacokinetics of the acyclovir pro-drug valaciclovir after escalating single- and multiple-dose administration to normal volunteers
    • Weller S, Blum R, Doucette M, et al. Pharmacokinetics of the acyclovir pro-drug valaciclovir after escalating single- and multiple-dose administration to normal volunteers. Clin Pharmacol Ther 1993;54:595-605.
    • (1993) Clin Pharmacol Ther , vol.54 , pp. 595-605
    • Weller, S.1    Blum, R.2    Doucette, M.3
  • 15
    • 79960387188 scopus 로고    scopus 로고
    • Valaciclovir versus aciclovir in patient initiated treatment of recurrent genital herpes: A randomised, double blind clinical trial
    • Bodsworth NJ, Crooks RJ, Borelli S, et al. Valaciclovir versus aciclovir in patient initiated treatment of recurrent genital herpes: a randomised, double blind clinical trial. Genitourin Med 1997;73:110-6.
    • (1997) Genitourin Med , vol.73 , pp. 110-116
    • Bodsworth, N.J.1    Crooks, R.J.2    Borelli, S.3
  • 16
    • 0031688110 scopus 로고    scopus 로고
    • Valaciclovir for the suppression of recurrent genital herpes simplex virus infection: A large-scale dose range-finding study
    • Reitano M, Tyring S, Lang W, et al. Valaciclovir for the suppression of recurrent genital herpes simplex virus infection: a large-scale dose range-finding study. J Infect Dis 1998;178:603-10.
    • (1998) J Infect Dis , vol.178 , pp. 603-610
    • Reitano, M.1    Tyring, S.2    Lang, W.3
  • 17
    • 79960404300 scopus 로고    scopus 로고
    • Valaciclovir for the suppression of recurrent genital HSV infection: A placebo controlled study of once-daily therapy
    • Patel R, Bodsworth N, Woolley P, et al. Valaciclovir for the suppression of recurrent genital HSV infection: a placebo controlled study of once-daily therapy. Genitourin Med 1997;73:105-9.
    • (1997) Genitourin Med , vol.73 , pp. 105-109
    • Patel, R.1    Bodsworth, N.2    Woolley, P.3
  • 18
    • 18244396615 scopus 로고    scopus 로고
    • Valaciclovir versus aciclovir for herpes simplex virus infection in HIV-infected individuals-two randomised trials
    • Conant MA, Schacker T, Murphy RL, et al. Valaciclovir versus aciclovir for herpes simplex virus infection in HIV-infected individuals-two randomised trials. Int J STD AIDS 2002;13:12-21.
    • (2002) Int J STD AIDS , vol.13 , pp. 12-21
    • Conant, M.A.1    Schacker, T.2    Murphy, R.L.3
  • 19
    • 0030022182 scopus 로고    scopus 로고
    • Preclinical development of antiviral drugs
    • Szczech GM. Preclinical development of antiviral drugs. Clin Infect Dis 1996;22:355-60.
    • (1996) Clin Infect Dis , vol.22 , pp. 355-360
    • Szczech, G.M.1
  • 20
    • 0032982665 scopus 로고    scopus 로고
    • Once-daily valacyclovir hydrochloride for suppression of recurrent genital herpes
    • Baker DA, Blythe JG, Miller JM. Once-daily valacyclovir hydrochloride for suppression of recurrent genital herpes. Obstet Gynecol 1999;94:103-6.
    • (1999) Obstet Gynecol , vol.94 , pp. 103-106
    • Baker, D.A.1    Blythe, J.G.2    Miller, J.M.3
  • 21
    • 0030773132 scopus 로고    scopus 로고
    • Manifestations resembling thrombotic microangiopathy in patients with advanced human immunodeficiency virus (HIV) disease in a cytomegalovirus prophylaxis trial (ACTG 204)
    • Bell WR, Chulay JD, Feinberg JE. Manifestations resembling thrombotic microangiopathy in patients with advanced human immunodeficiency virus (HIV) disease in a cytomegalovirus prophylaxis trial (ACTG 204). Medicine 1997;76:369-80.
    • (1997) Medicine , vol.76 , pp. 369-380
    • Bell, W.R.1    Chulay, J.D.2    Feinberg, J.E.3
  • 22
    • 0037089419 scopus 로고    scopus 로고
    • Randomized study of valacyclovir as prophylaxis against cytomegalovirus reactivation in recipients of allogeneic bone marrow transplants
    • Ljungman P, de la Camara R, Milpied N, et al. Randomized study of valacyclovir as prophylaxis against cytomegalovirus reactivation in recipients of allogeneic bone marrow transplants. Blood 2002;99:3050-6.
    • (2002) Blood , vol.99 , pp. 3050-3056
    • Ljungman, P.1    De la Camara, R.2    Milpied, N.3
  • 23
    • 6844258215 scopus 로고    scopus 로고
    • A randomized, double-blind trial of valaciclovir prophylaxis for cytomegalovirus disease in patients with advanced human immunodeficiency virus infection
    • Feinberg JE, Hurwitz S, Cooper D, et al. A randomized, double-blind trial of valaciclovir prophylaxis for cytomegalovirus disease in patients with advanced human immunodeficiency virus infection. J Infect Dis 1998;177:48-56.
    • (1998) J Infect Dis , vol.177 , pp. 48-56
    • Feinberg, J.E.1    Hurwitz, S.2    Cooper, D.3
  • 24
    • 0023802119 scopus 로고
    • Thrombotic thrombocytopenic purpura associated with human immunodeficiency virus type 1 (HIV-I) infection
    • Leaf AN, Laubenstein LJ, Raphael B, Hochster H, Baez L, Karpaktin S. Thrombotic thrombocytopenic purpura associated with human immunodeficiency virus type 1 (HIV-I) infection. Ann Intern Med 1988;109:194-7.
    • (1988) Ann Intern Med , vol.109 , pp. 194-197
    • Leaf, A.N.1    Laubenstein, L.J.2    Raphael, B.3    Hochster, H.4    Baez, L.5    Karpaktin, S.6
  • 25
    • 0033215318 scopus 로고    scopus 로고
    • Stability of valacyclovir hydrochloride in extemporaneously prepared oral liquids
    • Fish DN, Vidaurri VA, Deeter RG. Stability of valacyclovir hydrochloride in extemporaneously prepared oral liquids. Am J Health Syst Pharm 1999;56:1957-60.
    • (1999) Am J Health Syst Pharm , vol.56 , pp. 1957-1960
    • Fish, D.N.1    Vidaurri, V.A.2    Deeter, R.G.3
  • 26
    • 0036203239 scopus 로고    scopus 로고
    • Pharmacokinetics of acyclovir in immunocompromised children with leukopenia and mucositis after chemotherapy: Can intravenous acyclovir be substituted by oral valacyclovir?
    • Eksborg S, Pal N, Kalin M, Palm C, Soderhall S. Pharmacokinetics of acyclovir in immunocompromised children with leukopenia and mucositis after chemotherapy: can intravenous acyclovir be substituted by oral valacyclovir? Med Pediatr Oncol 2002;38:240-6.
    • (2002) Med Pediatr Oncol , vol.38 , pp. 240-246
    • Eksborg, S.1    Pal, N.2    Kalin, M.3    Palm, C.4    Soderhall, S.5
  • 28
    • 0037108444 scopus 로고    scopus 로고
    • An investigation of the steady-state pharmacokinetics of oral valacyclovir in immunocompromised children
    • in this issue
    • Nadal D, Leverger G, Sokal EM, et al. An investigation of the steady-state pharmacokinetics of oral valacyclovir in immunocompromised children. J Infect Dis 2002;186(Suppl 1):S123-30 (in this issue).
    • (2002) J Infect Dis , vol.186 , pp. S123-S130
    • Nadal, D.1    Leverger, G.2    Sokal, E.M.3
  • 29
    • 0033551348 scopus 로고    scopus 로고
    • Valacyclovir for the prevention of cytomegalovirus disease after renal transplantation
    • Lowance D, Neumayer HH, Legendre CM, et al. Valacyclovir for the prevention of cytomegalovirus disease after renal transplantation. N Engl J Med 1999;340:1462-70.
    • (1999) N Engl J Med , vol.340 , pp. 1462-1470
    • Lowance, D.1    Neumayer, H.H.2    Legendre, C.M.3
  • 30
    • 0031794904 scopus 로고    scopus 로고
    • Pharmacokinetics of oral valacyclovir and acyclovir in late pregnancy
    • Kimberlin DF, Weller S, Whitley R, et al. Pharmacokinetics of oral valacyclovir and acyclovir in late pregnancy. Am J Obstet Gynecol 1998;179:846-51.
    • (1998) Am J Obstet Gynecol , vol.179 , pp. 846-851
    • Kimberlin, D.F.1    Weller, S.2    Whitley, R.3
  • 31
    • 0026063125 scopus 로고
    • In vitro and in vivo characterization of herpes simplex virus clinical isolates recovered from patients infected with human immunodeficiency virus
    • Hill EL, Hunter GA, Ellis MN. In vitro and in vivo characterization of herpes simplex virus clinical isolates recovered from patients infected with human immunodeficiency virus. Antimicrob Agents Chemother 1991;35:2322-8.
    • (1991) Antimicrob Agents Chemother , vol.35 , pp. 2322-2328
    • Hill, E.L.1    Hunter, G.A.2    Ellis, M.N.3
  • 32
    • 0024354415 scopus 로고
    • Progressive esophagitis from acyclovir-resistant herpes simplex. Clinical roles for DNA polymerase mutants and viral heterogeneity?
    • Sacks SL, Wanklin RJ, Reece DE, et al. Progressive esophagitis from acyclovir-resistant herpes simplex. Clinical roles for DNA polymerase mutants and viral heterogeneity? Ann Intern Med 1989;111:893-9.
    • (1989) Ann Intern Med , vol.111 , pp. 893-899
    • Sacks, S.L.1    Wanklin, R.J.2    Reece, D.E.3
  • 33
    • 0028118607 scopus 로고
    • Foscarnet-resistant herpes simplex virus infection in patients with AIDS
    • Safrin S, Kemmer S, Plotkin B, et al. Foscarnet-resistant herpes simplex virus infection in patients with AIDS. J Infect Dis 1994;169:193-6.
    • (1994) J Infect Dis , vol.169 , pp. 193-196
    • Safrin, S.1    Kemmer, S.2    Plotkin, B.3
  • 34
    • 0002117901 scopus 로고    scopus 로고
    • Acyclovir-resistant herpes simplex virus: Preliminary results from a national surveillance system
    • Reyes M, Graber JM, Weatherall N, Hodges-Savola C, Reeves WC. Acyclovir-resistant herpes simplex virus: preliminary results from a national surveillance system. Antiviral Res 1998;37:A44.
    • (1998) Antiviral Res , vol.37 , pp. A44
    • Reyes, M.1    Graber, J.M.2    Weatherall, N.3    Hodges-Savola, C.4    Reeves, W.C.5
  • 35
    • 0031977160 scopus 로고    scopus 로고
    • Survey of resistance of herpes simplex virus to acyclovir in Northwest England
    • Christophers J, Clayton J, Craske J, et al. Survey of resistance of herpes simplex virus to acyclovir in northwest England. Antimicrob Agents Chemother 1998;42:868-72.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 868-872
    • Christophers, J.1    Clayton, J.2    Craske, J.3
  • 36
    • 0028334726 scopus 로고
    • Recurrence and resistance patterns of herpes simplex virus following cessation of ≥6 years of chronic suppression with acyclovir
    • Fife KH, Crumpacker CS, Mertz GJ, Hill EL, Boone GS, Acyclovir Study Group. Recurrence and resistance patterns of herpes simplex virus following cessation of ≥6 years of chronic suppression with acyclovir. J Infect Dis 1994;169:1338-41.
    • (1994) J Infect Dis , vol.169 , pp. 1338-1341
    • Fife, K.H.1    Crumpacker, C.S.2    Mertz, G.J.3    Hill, E.L.4    Boone, G.S.5
  • 37
    • 0027362888 scopus 로고
    • Brief report: Recurrent acyclovirresistant genital herpes in an immunocompetent patient
    • Kost RG, Hill EL, Tigges M, Straus SE. Brief report: recurrent acyclovirresistant genital herpes in an immunocompetent patient. N Engl J Med 1993;329:1777-82.
    • (1993) N Engl J Med , vol.329 , pp. 1777-1782
    • Kost, R.G.1    Hill, E.L.2    Tigges, M.3    Straus, S.E.4
  • 38
    • 0025237876 scopus 로고
    • Herpes simplex virus resistant to acyclovir. A study in a tertiary care center
    • Englund JA, Zimmerman ME, Swierkosz EM, et al. Herpes simplex virus resistant to acyclovir. A study in a tertiary care center. Ann Intern Med 1990;112:416-22.
    • (1990) Ann Intern Med , vol.112 , pp. 416-422
    • Englund, J.A.1    Zimmerman, M.E.2    Swierkosz, E.M.3
  • 39
    • 0002296281 scopus 로고    scopus 로고
    • Cross susceptibility patterns and neuro-virulence of acyclovir-resistant herpes simplex virus (HSV) isolates collected in a national surveillance study
    • Harden EA, Rybak RJ, Hartline C, et al. Cross susceptibility patterns and neuro-virulence of acyclovir-resistant herpes simplex virus (HSV) isolates collected in a national surveillance study. Antiviral Res 2000;46:A78.
    • (2000) Antiviral Res , vol.46 , pp. A78
    • Harden, E.A.1    Rybak, R.J.2    Hartline, C.3
  • 40
    • 0033887416 scopus 로고    scopus 로고
    • Antiviral susceptibilities of herpes simplex virus from immunocompetent subjects with recurrent herpes labialis: A UK-based survey
    • Boon RJ, Bacon TH, Robey HL, et al. Antiviral susceptibilities of herpes simplex virus from immunocompetent subjects with recurrent herpes labialis: a UK-based survey. J Antimicrob Chemother 2000;46:324-5.
    • (2000) J Antimicrob Chemother , vol.46 , pp. 324-325
    • Boon, R.J.1    Bacon, T.H.2    Robey, H.L.3
  • 41
    • 0001881217 scopus 로고    scopus 로고
    • Antiviral sensitivity of herpes simplex virus isolates from patients participating in the valaciclovir genital herpes simplex programme
    • Snowden W, Manohitharajah V, Crooks J. Antiviral sensitivity of herpes simplex virus isolates from patients participating in the valaciclovir genital herpes simplex programme. Antiinfective Drugs Chemother 1998;16(Suppl 1):19.
    • (1998) Antiinfective Drugs Chemother , vol.16 , pp. 19
    • Snowden, W.1    Manohitharajah, V.2    Crooks, J.3
  • 42
    • 0027757639 scopus 로고
    • Sensitivity monitoring of clinical isolates of herpes simplex virus to acyclovir
    • Collins P, Ellis MN. Sensitivity monitoring of clinical isolates of herpes simplex virus to acyclovir. J Med Virol 1993;(Suppl 1):58-66.
    • (1993) J Med Virol , pp. 58-66
    • Collins, P.1    Ellis, M.N.2
  • 43
    • 0002117901 scopus 로고    scopus 로고
    • Acyclovir-resistant herpes simplex virus: Characterization of virus isolates from a nationwide surveillance system
    • Weatherall NT, Hodges-Savola CA, Reyes M, et al. Acyclovir-resistant herpes simplex virus: characterization of virus isolates from a nationwide surveillance system. Antiviral Res 1998;37:A44.
    • (1998) Antiviral Res , vol.37 , pp. A44
    • Weatherall, N.T.1    Hodges-Savola, C.A.2    Reyes, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.