Aggregatibacter actinomycetemcomitans leukotoxin requires β-sheets 1 and 2 of the human CD11a β-propeller for cytotoxicity

Cellular Microbiology

Volumn 9, Issue 11, 2007, Pages 2689-2699

  Kieba, Irene R ^a   Fong, Karen P ^a   Tang, Hsin Yao ^b   Hoffman, Karl E ^a   Speicher, David W ^b   Klickstein, Lloyd B ^c   Lally, Edward T ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b WISTAR INSTITUTE   (United States)

^c NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BACTERIAL TOXIN; COMPLEMENTARY DNA; CYTOLYSIN; HETERODIMER; LEUKOTOXIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

AGGREGATIBACTER ACTINOMYCETEMCOMITANS; ALPHA CHAIN; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BETA SHEET; CELL KILLING; CONTROLLED STUDY; COW; CYTOLYSIS; CYTOTOXICITY; GENETIC TRANSFECTION; GRAM NEGATIVE BACTERIUM; HUMAN; HUMAN CELL; INFECTION SENSITIVITY; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; ANIMALS; ANTIGENS, CD11A; CATTLE; CELL LINE; CELL SURVIVAL; EXOTOXINS; FLOW CYTOMETRY; HUMANS; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MICE; MICROSCOPY, CONFOCAL; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS;

BOVINAE; MURINAE;

EID: 34848865691     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2007.00989.x     Document Type: Article

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