Identification by proteomic tool of atypical anti-liver/kidney microsome autoantibodies targets in de novo autoimmune hepatitis after liver transplantation

Annals of the New York Academy of Sciences

Volumn 1109, Issue , 2007, Pages 345-357

  Huguet, Stéphanie ^a,b   Vinh, Joelle ^c   Johanet, Catherine ^a,b   Samuel, Didier ^a,d   Gigou, Michèle ^a,d   Zamfir, Oana ^e   Duclos Vallée, Jean Charles ^a,d   Ballot, Eric ^a,b  

^a INSERM   (France)

^b HÔPITAL SAINT ANTOINE   (France)

^c PSL RESEARCH UNIVERSITY   (France)

^d HÔPITAL PAUL BROUSSE   (France)

^e CENTRE HOSPITALIER NATIONAL D OPHTALMOLOGIE DES QUINZE VINGTS   (France)

Author keywords

Atypical anti liver kidney microsome autoantibodies; De novo autoimmune hepatitis; Mass spectrometry; Proteomic

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; CARBONATE DEHYDRATASE III; PROTEASOME; ANTI LIVER KIDNEY MICROSOME ANTIBODY; ANTI-LIVER KIDNEY MICROSOME ANTIBODY; UNCLASSIFIED DRUG;

ADULT; AGED; AUTOIMMUNE HEPATITIS; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; DIAGNOSTIC TEST; FEMALE; HUMAN; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; ION TRAP MASS SPECTROMETRY; KIDNEY MICROSOME; LIVER MICROSOME; LIVER TRANSPLANTATION; MALE; PROTEIN ANALYSIS; PROTEOMICS; TWO DIMENSIONAL GEL ELECTROPHORESIS; ARTICLE; CYTOSOL; IMMUNOLOGY; MASS SPECTROMETRY; METHODOLOGY; MIDDLE AGED; PATHOLOGY; PROTEIN DATABASE;

RATTUS;

ADULT; AGED; AGED, 80 AND OVER; AUTOANTIBODIES; CYTOSOL; DATABASES, PROTEIN; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; HEPATITIS, AUTOIMMUNE; HUMANS; LIVER TRANSPLANTATION; MALE; MASS SPECTROMETRY; MIDDLE AGED; PROTEOMICS;

EID: 34848831220     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1398.041     Document Type: Conference Paper

References (22)

1. KERKAR, N., N. HADZIC, E.T. DAVIES, et al. 1998. De-novo autoimmune hepatitis after liver transplantation. Lancet 351: 409-413.
2. ALVAREZ, F., P.A. BERG, F. BIANCHI, et al. 1999. Review of criteria for diagnosis of auto-immune hepatitis. J. Hepatol. 31: 929-938.
3. SALCEDO, L., J. VAQUERO, R. BANARES, et al. 2002. Response to steroids in de novo autoimmune hepatitis after liver transplantation. Hepatology 35: 349-356.
4. MIELI-VERGANI, G. & D. VERGANI. 2004. De novo autoimmune hepatitis after liver transplantation. J. Hepatol. 40: 3-7.
5. AGUILERA, I., I. WICHMANN, J.M. SOUSA, et al. 2001. Antibodies against glutathione S-transferase T1 (GSTT1) in patients with de novo immune hepatitis following liver transplantation. Clin. Exp. Immunol. 126: 535-539.
6. DIAMOND, D.L., S.C. PROLL, J.M. JACOBS, et al. 2006. HepatoProteomics: applying proteomic technologies to the study of liver function and disease. Hepatology 44: 299-308.
7. VERRILLS, N.M. 2006. Clinical proteomics: present and future prospects. Clin. Biochem. Rev. 27: 99-116.
8. BEAUFAY, H. & A. AMAR-COSTESEC. 1976. Cell fractionation techniques. Methods Memb. Biol. 1: 1-100.
9. LAEMMLI, U. 1970. Cleavage of structural protein during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
10. GORG, A., C. OBERMAIER, G. BOGUTH, et al. 2000. The current state of two-dimensional electrophoresis with immobilized pH gradient. Electrophoresis 21: 1037-1053.
11. TOWBIN, H., T. STAEHELIN & J. GORDON. 1992. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. 1979. Biotechnology 24: 145-149.
12. SHEVCHENKO, A., M. WILM, O. VORM, et al. 1996. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem. 68: 850-858.
13. DUCRET, A., I. VAN OOSTVEEN, J.K. ENG, et al. 1998. High throughput protein characterization by automated reverse-phase chromatography/electrospray tandem mass spectrometry. Protein Sci. 7: 706-719.
14. SPEISEN, P. & M. PAGNI. 2005. JACOP: a simple and robust method for the automated classification of protein sequences with modular architecture. BMC Bioinformatics 6: 216-228.
15. WESIERSKA-GADEK J., H. LINDNER, E. HITCHMAN, et al. 2002. Anti-SLA seropositive autoimmune hepatitis sera recognize distinct subunits of glutathione Stransferase: high prevalence of the Ya autoantigen. Cell. Mol. Biol. 48: 301-307.
16. KATO, T., H. MIYAKAWA & M. ISHIBASHI. 2004. Frequency and significance of antiglutathione S-transferase autoantibody (anti-GST A1-1) in autoimmune hepatitis. J. Autoimmun. 22: 211-216.
17. ONO, Y., Y. RIDDERSTRALE, R.E. FORSTER, et al. 1992. Carbonic anhydrase in the membrane of the endoplasmic reticulum of male rat liver. Proc. Natl. Acad. Sci. USA 89: 11721-11725.
18. HOSODA H., M. OKAWA-TAKATSUJI, A. TANAKA, et al. 2004. Detection of autoantibody against carbonic anhydrase II in various liver diseases by enzyme-linked immunosorbent assay using appropriate conditions. Clin. Chim. Acta 342: 71-81.
19. NISHIMORI I., E. MIYAJI, K. MORIMOTO, et al. 2005. Serum antibodies to carbonic anhydrase IV in patients with autoimmune pancreatitis. Gut 54: 274-281.
20. FEIST, E., T. DORNER, U. KUCKELKORN, et al. 1996. Proteasome alpha-type subunit C9 is a primary target of autoantibodies in sera of patients with myositis and systemic lupus erythematosus. J. Exp. Med. 184: 1313-1318.
21. MAYO, I., J. ARRIBAS, P. VILLOSLADA, et al. 2002. The proteasome is a major autoantigen in multiple sclerosis. Brain 125: 2658-2667.
22. CHUANG S.M., L. CHEN, D. LAMBERTSON, et al. 2005. Proteasome-mediated degradation of cotranslationally damaged proteins involves translation elongation factor 1A. Mol. Cell. Biol. 25: 403-413.