-
1
-
-
0025779160
-
Tumor Necrosis Factor, new insights into the molecular mechanisms of its multiple action
-
J. Vilcek, and T. H. Lee, Tumor Necrosis Factor, new insights into the molecular mechanisms of its multiple action, J. Biol. Chem. 1991, 266, 7313-7316.
-
(1991)
J. Biol. Chem
, vol.266
, pp. 7313-7316
-
-
Vilcek, J.1
Lee, T.H.2
-
2
-
-
0035936797
-
-
R. M. Locksley, N. Killeen, and M. J. Lenardo, The TNF and TNF Receptor Review Superfamilies: Integrating Mammalian Biology, Cell 2001, 104, 487-501.
-
R. M. Locksley, N. Killeen, and M. J. Lenardo, The TNF and TNF Receptor Review Superfamilies: Integrating Mammalian Biology, Cell 2001, 104, 487-501.
-
-
-
-
3
-
-
0037180778
-
The inflammatory reflex
-
K. J. Tarcey, The inflammatory reflex, Nature, 2002, 420, 853-859.
-
(2002)
Nature
, vol.420
, pp. 853-859
-
-
Tarcey, K.J.1
-
4
-
-
11144356362
-
Discovery and structure-activity relationship of coumarin derivatives as TNF-α inhibitors
-
J. F. Cheng, M. Chen, D. Wallace, S. Tith,; T. Arrhenius, H. Kashiwagi, Y. Ono, A. Ishikawa, H. Sato, T. Kozono, H. Sato, and A.M. Nadzan, Discovery and structure-activity relationship of coumarin derivatives as TNF-α inhibitors Bioorg. Med. Chem. Lett. 2004, 14, 2411-2515.
-
(2004)
Bioorg. Med. Chem. Lett
, vol.14
, pp. 2411-2515
-
-
Cheng, J.F.1
Chen, M.2
Wallace, D.3
Tith, S.4
Arrhenius, T.5
Kashiwagi, H.6
Ono, Y.7
Ishikawa, A.8
Sato, H.9
Kozono, T.10
Sato, H.11
Nadzan, A.M.12
-
5
-
-
0029050742
-
Treatment of Crohn's Disease with Antitumor Necrosis Factor Chimeric Monoclonal Antibody (cA2)
-
H. M. Van Dulleman, S. J. H. Van Deventer, D. W. Hommes, H. A. Bijl, J. Jansen, G. N. Tytget, and J. Woody, Treatment of Crohn's Disease with Antitumor Necrosis Factor Chimeric Monoclonal Antibody (cA2), Gastroenterology 1995, 109, 129-135.
-
(1995)
Gastroenterology
, vol.109
, pp. 129-135
-
-
Van Dulleman, H.M.1
Van Deventer, S.J.H.2
Hommes, D.W.3
Bijl, H.A.4
Jansen, J.5
Tytget, G.N.6
Woody, J.7
-
6
-
-
24944521495
-
Novel Inhibitor of p38 MAP Kinase as an Anti-TNF-α Drug: Discovery of N-[4-[2-Ethyl-4-(3-methylphenyl)-1,3- thiazol-5-yl]-2-pyridyl]benzamide (TAK-715) as a Potent and Orally Active Anti-Rheumatoid Arthritis Agent
-
S. Miwatashi, Y. Arikawa, E. Kotani, M. Miyamoto, K. Naruo, H. Kimura, T. Tanaka, S. Asahi, and S. Ohkawa, Novel Inhibitor of p38 MAP Kinase as an Anti-TNF-α Drug: Discovery of N-[4-[2-Ethyl-4-(3-methylphenyl)-1,3- thiazol-5-yl]-2-pyridyl]benzamide (TAK-715) as a Potent and Orally Active Anti-Rheumatoid Arthritis Agent J. Med. Chem. 2005, 48, 5966-5979.
-
(2005)
J. Med. Chem
, vol.48
, pp. 5966-5979
-
-
Miwatashi, S.1
Arikawa, Y.2
Kotani, E.3
Miyamoto, M.4
Naruo, K.5
Kimura, H.6
Tanaka, T.7
Asahi, S.8
Ohkawa, S.9
-
7
-
-
21544450015
-
Psoriasis:TNF-α inhibitors and beyond
-
L. Kincaid, Psoriasis:TNF-α inhibitors and beyond, Drug Discov. Today 2005, 10, 884-886.
-
(2005)
Drug Discov. Today
, vol.10
, pp. 884-886
-
-
Kincaid, L.1
-
8
-
-
18444395237
-
Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF-B transcription factors
-
D. A. van Heel, I. A. Udalova, A. P. De Silva, D. P. McGovern, Y. Kinouchi, J. Hull, N. J. Lench, L. R. Cardon, A. H. Carey, D. P. Jewell and D. Kwiatkowski, Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF-B transcription factors, Human Molecular Genetics, 2002, 11, 1281-1289.
-
(2002)
Human Molecular Genetics
, vol.11
, pp. 1281-1289
-
-
van Heel, D.A.1
Udalova, I.A.2
De Silva, A.P.3
McGovern, D.P.4
Kinouchi, Y.5
Hull, J.6
Lench, N.J.7
Cardon, L.R.8
Carey, A.H.9
Jewell, D.P.10
Kwiatkowski, D.11
-
9
-
-
0028143211
-
Randomised Double-Blind Comparison of Chimeric Monoclonal Antibody to Tumour Necrosis Factor R (cA2) versus Placebo in Rheumatoid Arthritis
-
M. J. Elliott, R. N. Maini, M. Feldmann, J. R. Kalden, C. Antoni, J. S. Smolen, B. Leeb, F. C. Breedveld, J. D. Macfarlane, H. Bijl, and J. N. Woody, Randomised Double-Blind Comparison of Chimeric Monoclonal Antibody to Tumour Necrosis Factor R (cA2) versus Placebo in Rheumatoid Arthritis. Lancet 1994, 344, 1105-1110.
-
(1994)
Lancet
, vol.344
, pp. 1105-1110
-
-
Elliott, M.J.1
Maini, R.N.2
Feldmann, M.3
Kalden, J.R.4
Antoni, C.5
Smolen, J.S.6
Leeb, B.7
Breedveld, F.C.8
Macfarlane, J.D.9
Bijl, H.10
Woody, J.N.11
-
10
-
-
0013511183
-
Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)-Fc Fusion Protein
-
L. W. Moreland, S. W. Baumgartner, M. H. Schiff, E. A. Tindall, R. M. Fleischmann, A. L. Weaver, R. E. Ettlinger, S. Cohen, W. J. Koopman, K. Mohler, M. B. Widmer, and C. M. Blosch, Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)-Fc Fusion Protein, N. Engl. J. Med. 1997, 337, 141-147.
-
(1997)
N. Engl. J. Med
, vol.337
, pp. 141-147
-
-
Moreland, L.W.1
Baumgartner, S.W.2
Schiff, M.H.3
Tindall, E.A.4
Fleischmann, R.M.5
Weaver, A.L.6
Ettlinger, R.E.7
Cohen, S.8
Koopman, W.J.9
Mohler, K.10
Widmer, M.B.11
Blosch, C.M.12
-
11
-
-
0035046629
-
The Prospect of Treating Rheumatoid Arthritis with Recombinant Human Interleukin-1 Receptor Antagonist
-
B. Bresnihan, The Prospect of Treating Rheumatoid Arthritis with Recombinant Human Interleukin-1 Receptor Antagonist, BioDrugs BioDrugs 2001, 15, 87-97.
-
(2001)
BioDrugs BioDrugs
, vol.15
, pp. 87-97
-
-
Bresnihan, B.1
-
12
-
-
85066388178
-
-
M. Vracko and J. Gasteiger, A. QSAR Study on a Set of 105 Flavonoid Derivatives Using Descriptors Derived From 3D Structures, Internet Electron. J. Mol. Des. 2002, 1, 527-544, http://www.biochempress.com.
-
M. Vracko and J. Gasteiger, A. QSAR Study on a Set of 105 Flavonoid Derivatives Using Descriptors Derived From 3D Structures, Internet Electron. J. Mol. Des. 2002, 1, 527-544, http://www.biochempress.com.
-
-
-
-
13
-
-
14044255742
-
3D-QSAR of Cyclooxygenase-2 Inhibitors by Genetic Function Approximation
-
A. V. Raichurkar and V. M. Kulkarni, 3D-QSAR of Cyclooxygenase-2 Inhibitors by Genetic Function Approximation, Internet Electron. J. Mol. Des. 2003, 2, 242-261, http://www.biochempress.com.
-
(2003)
Internet Electron. J. Mol. Des
, vol.2
, pp. 242-261
-
-
Raichurkar, A.V.1
Kulkarni, V.M.2
-
14
-
-
34247266707
-
3D-QSAR of Protein Tyrosine Phosphatase 1B Inhibitors by Genetic Function Approximation
-
S. M. Vadlamudi and V. M. Kulkarni, 3D-QSAR of Protein Tyrosine Phosphatase 1B Inhibitors by Genetic Function Approximation, Internet Electron. J. Mol. Des. 2004, 3, 586-609, http://www. biochempress.com.
-
(2004)
Internet Electron. J. Mol. Des
, vol.3
, pp. 586-609
-
-
Vadlamudi, S.M.1
Kulkarni, V.M.2
-
15
-
-
0030046730
-
Substituted xanthines, pteridinediones, and related compounds as potential antiinflammatory agents. Synthesis and biological evaluation of inhibitors of tumor necrosis factor alpha
-
H. B. Cottam, H. Shih, L. R. Tehrani, D. B. Wasson, and D. A. Carson, Substituted xanthines, pteridinediones, and related compounds as potential antiinflammatory agents. Synthesis and biological evaluation of inhibitors of tumor necrosis factor alpha, J. Med. Chem. 1996, 39, 02-09.
-
(1996)
J. Med. Chem
, vol.39
, pp. 02-09
-
-
Cottam, H.B.1
Shih, H.2
Tehrani, L.R.3
Wasson, D.B.4
Carson, D.A.5
-
16
-
-
85066390024
-
-
CS Chem Office, Version 6.0, Cambridge Soft Corporation, Washington D.C. USA
-
CS Chem Office, Version 6.0, Cambridge Soft Corporation, Washington D.C. USA.
-
-
-
-
17
-
-
85066390695
-
-
DRAGON Software Version 3.0, 2003, by R. Todeschini, V. Consonni, A. Mauri and M. Pawan, Milano Chemometrics, Italy
-
DRAGON Software (Version 3.0 - 2003), by R. Todeschini, V. Consonni, A. Mauri and M. Pawan, Milano Chemometrics, Italy.
-
-
-
-
19
-
-
33748311541
-
QSAR analysis of indomethacin derivatives as selective COX-2 inhibitors
-
H. K. Jain and R. K. Agrawal, QSAR analysis of indomethacin derivatives as selective COX-2 inhibitors, Internet Electron. J. Mol. Des. 2006, 5, 224-236, http://www.biochempress.com.
-
(2006)
Internet Electron. J. Mol. Des
, vol.5
, pp. 224-236
-
-
Jain, H.K.1
Agrawal, R.K.2
-
20
-
-
33748329448
-
Inhibitory mode of 2-acetoxyphenyl alkyl sulfides against COX-1 and COX-2: QSAR analyses
-
H. K. Jain and R. K. Agrawal, Inhibitory mode of 2-acetoxyphenyl alkyl sulfides against COX-1 and COX-2: QSAR analyses, Bioorg. Med. Chem. Lett. 2006, 16, 5280-5284.
-
(2006)
Bioorg. Med. Chem. Lett
, vol.16
, pp. 5280-5284
-
-
Jain, H.K.1
Agrawal, R.K.2
-
21
-
-
85066388911
-
-
R. Todeschini and V. Consonni, Handbook of molecular descriptors, Wiley-VCH Verlag GmbH, Weinheim, Germany
-
R. Todeschini and V. Consonni, Handbook of molecular descriptors, Wiley-VCH Verlag GmbH, Weinheim, Germany.
-
-
-
-
22
-
-
0013445006
-
-
SYSTAT, University of Waterloo, Department of Statistics and Actuarial Science, September 1
-
SYSTAT, Instruction Manual, University of Waterloo, Department of Statistics and Actuarial Science, September 1, 1998.
-
(1998)
Instruction Manual
-
-
-
23
-
-
19944418542
-
VALSTAT: Validation program for Quantitative Structure Activity Relationships Studies
-
A. K. Gupta, M. A. Babu and S. G. Kaskhedikar, VALSTAT: Validation program for Quantitative Structure Activity Relationships Studies, Indian J. Pharm. Sci. 2004, 66, 396-402.
-
(2004)
Indian J. Pharm. Sci
, vol.66
, pp. 396-402
-
-
Gupta, A.K.1
Babu, M.A.2
Kaskhedikar, S.G.3
-
24
-
-
33244488303
-
Topological descriptors in modeling the antimalarial activity of 4-(3′,53′-disubstituted anilino)quinolines
-
M. K. Gupta and Y. S. Prabhakar, Topological descriptors in modeling the antimalarial activity of 4-(3′,53′-disubstituted anilino)quinolines, J. Chem. Inf. Model. 2006, 46, 93-102.
-
(2006)
J. Chem. Inf. Model
, vol.46
, pp. 93-102
-
-
Gupta, M.K.1
Prabhakar, Y.S.2
|