Conduction reserve and arrhythmias

Netherlands Heart Journal

Volumn 14, Issue 3, 2006, Pages 113-116

  Stein, M ^a   Boulaksil, M ^a,b   Engelen, M A ^a   Van Veen, T A B ^a   Hauer, R N W ^a   De Bakker, J M T ^a,b,c   Van Rijen, H V M ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM CHANNEL;

ARTICLE; BRUGADA SYNDROME; HEART ARRHYTHMIA; HEART CONDUCTION; HEART FAILURE; HEART RHYTHM; HEART RIGHT VENTRICLE; HUMAN; NONHUMAN; PROGRESSIVE CARDIAC CONDUCTION DEFECT; PROTEIN EXPRESSION;

EID: 34848825635     PISSN: 15685888     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Coumel P. The management of clinical arrhythmias. An overview on invasive versus non-invasive electrophysiology. Eur Heart J 1987;8:92-9.
2. Winterton SJ, Turner MA, O'Gorman DJ, Flores NA, Sheridan DJ. Hypertrophy causes delayed conduction in human and guinea pig myocardium: accentuation during ischaemic perfusion. Cardiovas Res 1994;28:47-54.
3. Cooklin M, Wallis WRJ, Sheridan DJ, Fry CH. Changes in cell-to-cell electrical coupling associated with left ventricular hypertrophy. Circulation Res 1997;80:765-71.
4. Borlak J, Thum T. Hallmarks of ion channel gene expression in end-stage heart failure. Faseb J 2003;17:1592-608.
5. Valdivia CR, Chu WW, Pu J, Foell JD, Haworth RA, Wolff MR, et al. Increased late sodium current in myocytes from a canine heart failure model and from failing human heart. J Mol Cell Cardiol 2005;38:475-83.
6. Peters NS. New insights into myocardial arrhythmogenesis: Distribution of gap junctional coupling in normal ischemic and hypertrophied human hearts. Clin Sci 1996;90:447-52.
7. Yamada KA, Rogers JG, Sundset R, Steinberg TH, Saffitz JE. Up-regulation of connexin45 in heart failure. J Cardiovasc Electrophysiol 2003;14:1205-12.
8. Kostin S, Dammer S, Hein S, Klovekorn WP, Bauer EP, Schaper J. Connexin 43 expression and distribution in compensated and decompensated cardiac hypertrophy in patients with aortic stenosis. Cardiovasc Res 2004;62:426-36.
9. Kawara T, Derksen R, de Groot JR, Coronel R, Tasseron S, Linnenbank AC, et al. Activation delay after premature stimulation in chronically diseased human myocardium relates to the architecture of interstitial fibrosis. Circulation 2001;104:3069-75.
10. Morley GE, Vaidya D, Samie FH, Lo C, Delmar M, Jalife J. Characterization of conduction in the ventricles of normal and heterozygous Cx43 knockout mice using optical mapping. J Cardiovasc Electrophysiol 1999;10:1361- 75.
11. Van Rijen HVM, Eckardt D, Degen J, Theis M, Ott T, Willecke K, et al. Slow conduction and enhanced anisotropy increase the propensity for ventricular tachyarrhythmias in adult mice with induced deletion of connexin43. Circulation 2004;109:1048-55.
12. Van Veen TA, Stein M, Royer A, Le Quang K, Charpentier F, Colledge WH, et al. Impaired Impulse Propagation in Scn5a-Knockout Mice. Combined Contribution of Excitability, Connexin Expression, and Tissue Architecture in Relation to Aging. Circulation 2005;112(13):1927-35.
13. Royer A, van Veen TA, Le Bouter S, Marionneau C, Griol-Charhbili V, Leoni AL, et al. Mouse model of SCN5A-linked hereditary Lenegre's disease: age-related conduction slowing and myocardial fibrosis. Circulation 2005;111:1738-46.
14. Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol 1992;20:1391-6.
15. Antzelevitch C, Brugada P, Brugada J, Brugada R, Shimizu W, Gussak I, et al. Brugada syndrome: a decade of progress. Circ Res 2002;91:1114- 8.
16. Probst V, Kyndt F, Potet F, Trochu JN, Mialet G, Demolombe S, et al. Haploinsufficiency in combination with aging causes SCN5A-linked hereditary Lenegre disease. J Am Coll Cardiol 2003;41:643-52.
17. Coronel R, Casini S, Koopmann TT, Wilms-Schopman FJ, Verkerk AO, de Groot JR, et al. Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and computational study. Circulation 2005;112:2769-77.
18. Olson TM, Michels VV, Ballew JD, Reyna SP, Karst ML, Herron KJ, et al. Sodium channel mutations and susceptibility to heart failure and atrial fibrillation. JAMA 2005;293:447-54.