Differential expression of neurogenins and NeuroD1 in human pituitary tumours

Journal of Endocrinology

Volumn 194, Issue 3, 2007, Pages 475-484

  Fratticci, A ^a   Grieco, F A ^a   Spilioti, C ^a   Giangaspero, F ^b,c   Ventura, L ^d   Esposito, V ^b,e   Piccirilli, M ^e   Santoro, A ^e   Gulino, A ^b,c   Cantore, G ^b   Alesse, E ^a   Jaffrain Rea, M L ^a,b,f  

^a UNIVERSITY OF L'AQUILA   (Italy)

^b IRCCS NEUROMED   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d S Salvatore Hospital   (Italy)

^e POLICLINICO UMBERTO I   (Italy)

^f Fondazione 'Carlo Ferri'   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE RECEPTOR STIMULATING AGENT; HELIX LOOP HELIX PROTEIN; NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIN 1; NEUROGENIN 2; NEUROGENIN 3; SOMATOSTATIN DERIVATIVE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ACTH SECRETING ADENOMA; ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; HYPOPHYSIS ADENOMA; HYPOPHYSIS TUMOR; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADENOMA; ADOLESCENT; ADRENOCORTICOTROPIC HORMONE; ADULT; AGED; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; CHILD; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GROWTH HORMONE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NERVE TISSUE PROTEINS; PITUITARY NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STATISTICS, NONPARAMETRIC;

EID: 34748916457     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/JOE-07-0020     Document Type: Article

References (36)

1. Cau E, Casarosa S & Guillemot F 2002 Mash1 and Ngn1 control distinct steps of determination and differentiation in the olfactory sensory neuron lineage. Development 129 1871-1880.
2. Chae JH, Stein GH & Lee JE 2004 NeuronD: the predicted and the surprising. Molecules and Cells 18 271-288.
3. Cho JH, Kwon IS, Kim S, Ghil SH, Tsa MJ, Kim YS, Lee YD & Suh-Kim H 2001 Overexpression of BETA2/NeuronD induces neurite outgrowth in F11 neuroblastoma cells. Journal of Neurochemistry 77 103-tO9.
4. Dasen JS & Rosenfeld MG 2001 Signaling and transcriptional mechanisms in pituitary development. Annual Review of Neuroscience 24 327-355.
5. Edlund H 1999 Pancreas: how to get there from the gut? Current Opinion in Cell Biology 11 663-668.
6. Ferretti E, Di Stefano D, Zazzeroni F, Gallo R, Fratticci A, Carfagnini R, Angiualli S, Santoro A, Minniti G, Tamburrano G et al. 2003 Human pituitary tumours express the bHLH transcription factors NeuroD1 and ASH1. Journal of Endocrinological Investigation 26 957-965.
7. Gittoes JL 1998 Current perspectives on the pathogenesis of non-functioning pituitary tumours. Journal of Endocrinology 157 177-186.
8. Gradwohl G, Dierich A, LeMeur M & Guillemot F 2000 Neurogenin3 is required for the development of the four cell lineages of the pancreas. PNAS 97 1607-1611.
9. Greenwood AL, Turner EE & Anderson DJ 1999 Identification of dividing, determined sensory neuron precursors in the mammalian neural crest. Development 126 3545-3559.
10. Huang HP, Liu M, El-Hodiri HM, Chu K, Jamrich M & Tsai MJ 2000 Regulation of the pancreatic islet-specific gene BETA2 (NeuroD) by neurogenin3. Molecular and Cellular Biology 20 3292-3307.
11. Ito T, Udaka N, Yazawa T, Okudela K, Hayashi H, Sudo T, Guillemot F, Kageyama R & Kitamura H 2000 Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development 127 3913-3921.
12. Ivanova A, Liao SY, Lerman MI, Ivanov S & Stanbridge EJ 2005 STRA13 expression and subcellular localisation in normal and tumour tissues: implications for use as a diagnostic and differentiation marker. Journal of Medical Genetics 42 565-576.
13. Jackson SM, Barnhart KM, Mellon PL, Gutierrez-Hartmann A & Hoffler JP 1993 Helix-loop-helix proteins are present and differentially expressed in different cell lines from the anterior pituitary. Molecular and Cellular Endocrinology 96 167-176.
14. Jaffrain-Rea ML, Di Stefano D, Minniti G, Esposito V, Bultrini A, Ferretti E, Santoro A, Faticanti Scucchi L, Gulino A & Cantore G 2002 A critical reappraisal of MIB-1 labelling index significance in a large series of pituitary tumors: secreting versus non secreting adenomas. Endocrine Related Cancer 9 103-113.
15. Kim S, Ghil SH, Kim SS, Myeong HH, Lee YD & Suh-Kim H 2002 Overexpression of neurogenin1 induces neurine outgrowth in F11 neuroblostoma cells. Experimental and Molecular Medicine 34 469-475.
16. Kwok WK, Ling MT, Lee TW et al. 2005 Upregulation of TWIST in prostate cancer and its implication as a therapeutic target. Cancer Research 65 5153-5161
17. Lamolet B, Pulichino AM, Lamonerie T, Gauthier Y, Brue T, Enjalbert A & Drouin J 2001 A pituitary cell-restricred T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins. Cell 104 849-839.
18. Lamolet B, Poulin G, Chu K, Guillemot F, Tsai MJ & Drouin J 2004 Tpit-independent function of NeuroD1(BETA2) in pituitary corticotroph differentiation. Molecular Endocrinology 18 995-1003.
19. Lanigan TM, DeRaad SK & Russo AF 1998 Requirement of the Mash-1 transcription factor for neuroendocrine differentiation of thyroid C cells. Journal of Neurobiology 34 126-134.
20. Ma Q, Fode C, Guillemot F & Anderson DJ 1999 Neurogenin1 and neurogenin2 control two distinct waves of neurogenesis in developing dorsal rove ganglia. Genes and Development 13 1717-1728.
21. Mantovani G, Asteria C, Pellegrini C, Bosari S, Alberti L, Bondioni S, Peverelli E, Spada A & Beck-Peccoz P 2006 HESX1 expression in human normal pituitaries and pituitary adenomas. Molecular and Cellular Endocrinology 247 135-139.
22. Marx L, Arck P, Kapp M, Kieslich C & Dietl J 1999 Leukocyre populations, hormone receptors and apoptosis in europic and ecropic firts trimestre human pregnancies. Human Reporduction 14 1111-1117.
23. Massari ME & Murre C 2000 Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms. Molecular and Cellular Biology 20 429-440.
24. Nakakura EK, Sriuranpong VR, Nakakura EK, Sriuranpong VK, Kunnimalaiyaan M, Hsiao EC, Schuebel KE, Borges MW, Jin N, Collins BJ et al. 2005 Regulation of neuroenclocrine differemiation in gastrointestinal carcinoid runiour cells by Notch signaling. Journal of Clinical Endocrinology and Metabolism 90 4350-4356.
25. Nakamura S, Othsuru A, Nakamura S, Ohtsuru A, Takamura N, Kitange G, Tokunaga Y, Yasunaga A, Shibata S & Yamashita S 1999 Prop-1 gene expression in human pituitary tumours. Journal of Clinical Endocrinology and Metabolism 84 2581-2584.
26. Oyama K, Sanno N, Teramoto A & Osamura RY 2001 Expression of Neuro, D1 in human normal pituitaries and pituitary adenomas. Modern Pathology 14 892-899.
27. Pellegrini I, Barlier A, Gunz G, Figarella-Branger D, Enjalbert A, Grisoli F & Jaquet P 1994 Pit-1 gene expression in the human pituitary and pituitary adenomas. Journal of Clinical Endocrinology and Metabolism 79 189-196.
28. Pellegrini-Bouiller I, Marnique C, Gunz G, Grino M, Zamora A, Figarella-Branger D, Grisoli F, Jaquet P & Enjalbert A 1999 Expression of the members of the Ptx family of transcription factors in human pituitary adenomas. Journal of Clinical Endocrinology and Metabolism 84 2212-2220.
29. Pogoda HM, von der Hardt S, Kramer C, Schwarz H & Hemmerschmidt M 2006 The proneural ascl1 is required for endocrine differentiation and cell survival in the zebrafish adenohypophysis. Development 133 1079-1089.
30. Poulin G, Turgon B & Drouin J 1997 NeuroD1/BETA2 contributes to cell-specific transcription of the POMC gene. Molecular and Cellular Biology 17 6673-6682.
31. Poulin G, Lebel M, Chamberland M, Paradis FW & Drouin J 2000 Specific protein-protein intrection between basix helix-loop-helix transcription factors and homeoproteins of the Pitx family. Molecular and Cellular Biology 20 4826-4837.
32. Ross SE, Greenberg ME & Stiles CD 2003 Basic helix-loop-helix factors in cortical development. Neuron 39 13-25.
33. Rostomily RC, Bermingham-Mc Donogh O, Berger MS, Tapscott SJ, Reh TA & Olson JM 1997 Expression of neurogenic basic helix-loop-helix genes in primitive neuroectodermal tumors. Cancer Research 57 3526-3531.
34. Semenza GL 2002 Involvement of hypoxia-inducible factor 1 in human cancer. Internal Medicine 41 79-83.
35. Söderholm H, Ortoft E, Johansson I, Ljungberg J, Larssou C, Axelson H & Pahlman S 1999 Human Achaete-scute homologue 1 (HASH1) is downregulated in differentiating neuroblastoma cells. Biochemical and Biophysical Research Communications 256 557-563.
36. Wilson CB 1984 A decade of pituirary microsurgery: The Herbert Olivecrona Lecture. Journal of Neurosurgery 61 814-833.