The proliferation center microenvironment and prognostic markers in chronic lymphocytic leukemia/small lymphocytic lymphoma

Human Pathology

Volumn 37, Issue 2, 2006, Pages 152-159

  Soma, Lorinda A ^a   Craig, Fiona E ^a   Swerdlow, Steven H ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

B cells; CD38; Chronic lymphocytic leukemia small lymphocytic lymphoma; Lymphoma; MUM1 IRF4; Proliferation centers; ZAP 70

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD38 ANTIGEN; INTERFERON REGULATORY FACTOR 4; PROTEIN KINASE ZAP 70;

ADULT; AGED; ARTICLE; B LYMPHOCYTE; CELL PROLIFERATION; CELL STIMULATION; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE; MALE; MICROENVIRONMENT; PROGNOSIS; PROTEIN EXPRESSION;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD38; CELL PROLIFERATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; INTERFERON REGULATORY FACTORS; LEUKEMIA, LYMPHOCYTIC, CHRONIC; MALE; MEMBRANE GLYCOPROTEINS; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 30744467923     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2005.09.029     Document Type: Article

References (37)

1. M. Ferrarini, and N. Chiorazzi Recent advances in the molecular biology and immunobiology of chronic lymphocytic leukemia Semin Hematol 41 2004 207 223
2. T.J. Hamblin, Z. Davis, A. Gardiner, D.G. Oscier, and F.K. Stevenson Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia [see comments] Blood 94 1999 1848 1854
3. R.N. Damle, T. Wasil, and F. Fais Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia [see comments] Blood 94 1999 1840 1847
4. T.J. Hamblin, J.A. Orchard, A. Gardiner, D.G. Oscier, Z. Davis, and F.K. Stevenson Immunoglobulin V genes and CD38 expression in CLL Blood 95 2000 2455 2457
5. T.J. Hamblin, J.A. Orchard, and R.E. Ibbotson CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease Blood 99 2002 1023 1029
6. D.G. Oscier, A. Thompsett, D. Zhu, and F.K. Stevenson Differential rates of somatic hypermutation in V(H) genes among subsets of chronic lymphocytic leukemia defined by chromosomal abnormalities Blood 89 1997 4153 4160
7. D.G. Oscier, A.C. Gardiner, and S.J. Mould Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors Blood 100 2002 1177 1184
8. M. Crespo, F. Bosch, and N. Villamor ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia N Engl J Med 348 2003 1764 1775
9. A. Wiestner, A. Rosenwald, and T.S. Barry ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile Blood 101 2003 4944 4951
10. J.A. Orchard, R.E. Ibbotson, Z. Davis, A. Wiestner, A. Rosenwald, and P.W. Thomas ZAP-70 Expression and prognosis in chronic lymphocytic leukaemia Lancet 363 2004 105 111
11. J. Carreras, N. Villamor, and L. Colomo Immunohistochemical analysis of ZAP-70 expression in B-cell lymphoid neoplasms J Pathol 205 2005 507 513
12. P. Ghia, G. Guida, and S. Stella The pattern of CD38 expression defines a distinct subset of chronic lymphocytic leukemia (CLL) patients at risk of disease progression Blood 101 2003 1262 1269
13. O. Jaksic, M.M. Paro, I. Kardum Skelin, R. Kusec, V. Pejsa, and B. Jaksic CD38 on B-cell chronic lymphocytic leukemia cells has higher expression in lymph nodes than in peripheral blood or bone marrow Blood 103 2004 1968 1969
14. C.C. Chang, J. Lorek, and D.E. Sabath Expression of MUM1/IRF4 correlates with clinical outcome in patients with B-cell chronic lymphocytic leukemia Blood 100 2002 4671 4675
15. M. Ito, S. Iida, and H. Inagaki MUM1/IRF4 expression is an unfavorable prognostic factor in B-cell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) Jpn J Cancer Res 93 2002 685 694
16. L. Chen, G. Widhopf, and L. Huynh Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia Blood 100 2002 4609 4614
17. S.H. Swerdlow, L.J. Murray, J.A. Habeshaw, and A.G. Stansfeld Lymphocytic lymphoma/B-chronic lymphocytic leukaemia-an immunohistopathological study of peripheral B lymphocyte neoplasia Br J Cancer 50 1984 587 599
18. I.A. Lampert, A. Wotherspoon, S. Van Noorden, and R.P. Hasserjian High expression of CD23 in the proliferation centers of chronic lymphocytic leukemia in lymph nodes and spleen Hum Path 30 1999 648 654
19. L. Granziero, P. Ghia, and P. Circosta Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia Blood 97 2001 2777 2783
20. M. Bonato, S. Pittaluga, and A. Tierens Lymph node histology in typical and atypical chronic lymphocytic leukemia Am J Surg Pathol 22 1998 49 56
21. S.L. Asplund, R.W. McKenna, M.S. Howard, and S.H. Kroft Immunophenotype does not correlate with lymph node histology in chronic lymphocytic leukemia/small lymphocytic lymphoma Am J Surg Pathol 26 2002 624 629
22. H.K. Muller-Hermelink, D. Catovsky, E. Montserrat, and N.L. Harris Chronic lymphocytic leukaemia/small lymphocytic lymphoma E.S. Jaffe N.L. Harris H. Stein J.W. Vardiman Pathology and genetics of tumours of haematopoietic and lymphoid tissues 2001 IARC Press Lyon 127 130
23. K. Lennert Histopathology of non-Hodgkin's lymphomas (based on the Kiel classification) 1981 Springer Berlin
24. C.C. Chen, R.B. Raikow, E. Sonmez-Alpan, and S.H. Swerdlow Classification of small B-cell lymphoid neoplasms using a paraffin section immunohistochemical panel Appl Immunohistochem Mol Morphol 8 2000 1 11
25. S. Fournier, M. Rubio, G. Delespesse, and M. Sarfati Role for low-affinity receptor for IgE (CD23) in normal and leukemic B-cell proliferation Blood 84 1994 1881 1886
26. M. Sarfati, S. Chevret, and C. Chastang Prognostic importance of serum soluble CD23 level in chronic lymphocytic leukemia Blood 88 1996 4259 4264
27. H. Stein, A. Bonk, G. Tolksdorf, K. Lennert, H. Rodt, and J. Gerdes Immunohistologic analysis of the organization of normal lymphoid tissue and non-Hodgkin's lymphomas J Histochem Cytochem 28 1980 746 760
28. S. Barrena, J. Almeida, and M. Yunta Aberrant expression of tetraspanin molecules in B-cell chronic lymphoproliferative disorders and its correlation with normal B-cell maturation Leukemia 19 2005 1376 1383
29. T.H. Totterman, K. Nilsson, L. Clasesson, B. Simonsson, and P. Aman Differentiation of chronic lymphocytic leukaemia cells in vitro: I. Phorbol ester-induced changes in the synthesis of immunoglobulin and HLA-DR Hum Lymphocyte Diff 1 1981 13 26
30. U. Klein, Y. Tu, and G.A. Stolovitzky Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells J Exp Med 194 2001 1625 1638
31. A. Rosenwald, A.A. Alizadeh, and G. Widhopf Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia J Exp Med 194 2001 1639 1647
32. J.C. Nolz, R.C. Tschumper, B.T. Pittner, J.R. Darce, N.E. Kay, and D.F. Jelinek ZAP-70 is expressed by a subset of normal human B-lymphocytes displaying an activated phenotype Leukemia 2005
33. A.C. Chan, M. Iwashima, C.W. Turck, and A. Weiss ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain Cell 71 1992 649 662
34. A.C. Chan, N.S. van Oers, and A. Tran Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling J Immunol 152 1994 4758 4766
35. E. Schweighoffer, L. Vanes, A. Mathiot, T. Nakamura, and V.L. Tybulewicz Unexpected requirement for ZAP-70 in pre-B cell development and allelic exclusion Immunity 18 2003 523 533
36. B. Falini, M. Fizzotti, and A. Pucciarini A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells Blood 95 2000 2084 2092
37. K. Tsuboi, S. Iida, and H. Inagaki MUM1/IRF4 expression as a frequent event in mature lymphoid malignancies Leukemia 14 2000 449 456