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Volumn 373, Issue 3, 2007, Pages 695-705

Structural Elements Underlying the High Binding Affinity of Human Cytomegalovirus UL18 to Leukocyte Immunoglobulin-like Receptor-1

Author keywords

cytomegalovirus; human; ILT2 CD85j LILRB1; MHC class I; viral homologue

Indexed keywords

DISULFIDE; LEUKOCYTE IMMUNOGLOBULIN LIKE RECEPTOR 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; UL18 ANTIGEN; UNCLASSIFIED DRUG;

EID: 34748843922     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.08.020     Document Type: Article
Times cited : (14)

References (51)
  • 1
    • 34748906708 scopus 로고    scopus 로고
    • Knipe D.M., Griffin D.E., Lamb R.A., Martin M.A., Roizman B., and Strauss S.E. (Eds), Lippincott William & Wilkins, Philadelphia
    • Mocarski E.J.J. In: Knipe D.M., Griffin D.E., Lamb R.A., Martin M.A., Roizman B., and Strauss S.E. (Eds). Cytomegaloviruses and their Replication: Virology, 5th edit. vol. 2 (2006), Lippincott William & Wilkins, Philadelphia
    • (2006) Cytomegaloviruses and their Replication: Virology, 5th edit. , vol.2
    • Mocarski, E.J.J.1
  • 2
    • 0034106633 scopus 로고    scopus 로고
    • Down-regulation of MHC class I antigen presentation by HCMV; lessons for tumor immunology
    • Tortorella D., Gewurz B., Schust D., Furman M., and Ploegh H. Down-regulation of MHC class I antigen presentation by HCMV; lessons for tumor immunology. Immunol. Invest. 29 (2000) 97-100
    • (2000) Immunol. Invest. , vol.29 , pp. 97-100
    • Tortorella, D.1    Gewurz, B.2    Schust, D.3    Furman, M.4    Ploegh, H.5
  • 3
    • 0035690939 scopus 로고    scopus 로고
    • Virus infections: escape, resistance, and counterattack
    • Xu X.N., Screaton G.R., and McMichael A.J. Virus infections: escape, resistance, and counterattack. Immunity 15 (2001) 867-870
    • (2001) Immunity , vol.15 , pp. 867-870
    • Xu, X.N.1    Screaton, G.R.2    McMichael, A.J.3
  • 4
    • 13944249948 scopus 로고    scopus 로고
    • Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141
    • Tomasec P., Wang E.C., Davison A.J., Vojtesek B., Armstrong M., Griffin C., et al. Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141. Nature Immunol. 6 (2005) 181-188
    • (2005) Nature Immunol. , vol.6 , pp. 181-188
    • Tomasec, P.1    Wang, E.C.2    Davison, A.J.3    Vojtesek, B.4    Armstrong, M.5    Griffin, C.6
  • 5
    • 3142781416 scopus 로고    scopus 로고
    • Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D
    • Bacon L., Eagle R.A., Meyer M., Easom N., Young N.T., and Trowsdale J. Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D. J. Immunol. 173 (2004) 1078-1084
    • (2004) J. Immunol. , vol.173 , pp. 1078-1084
    • Bacon, L.1    Eagle, R.A.2    Meyer, M.3    Easom, N.4    Young, N.T.5    Trowsdale, J.6
  • 6
    • 18244367112 scopus 로고    scopus 로고
    • Inhibition of the NKp30 activating receptor by pp65 of human cytomegalovirus
    • Arnon T.I., Achdout H., Levi O., Markel G., Saleh N., Katz G., et al. Inhibition of the NKp30 activating receptor by pp65 of human cytomegalovirus. Nature Immunol. 6 (2005) 515-523
    • (2005) Nature Immunol. , vol.6 , pp. 515-523
    • Arnon, T.I.1    Achdout, H.2    Levi, O.3    Markel, G.4    Saleh, N.5    Katz, G.6
  • 8
    • 0035099068 scopus 로고    scopus 로고
    • ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor
    • Cosman D., Mullberg J., Sutherland C.L., Chin W., Armitage R., Fanslow W., et al. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity 14 (2001) 123-133
    • (2001) Immunity , vol.14 , pp. 123-133
    • Cosman, D.1    Mullberg, J.2    Sutherland, C.L.3    Chin, W.4    Armitage, R.5    Fanslow, W.6
  • 9
    • 0034635414 scopus 로고    scopus 로고
    • Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40
    • Tomasec P., Braud V.M., Rickards C., Powell M.B., McSharry B.P., Gadola S., et al. Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40. Science 287 (2000) 1031-1033
    • (2000) Science , vol.287 , pp. 1031-1033
    • Tomasec, P.1    Braud, V.M.2    Rickards, C.3    Powell, M.B.4    McSharry, B.P.5    Gadola, S.6
  • 10
    • 33744990829 scopus 로고    scopus 로고
    • Down-regulation of the NKG2D ligand MICA by the human cytomegalovirus glycoprotein UL142
    • Chalupny N.J., Rein-Weston A., Dosch S., and Cosman D. Down-regulation of the NKG2D ligand MICA by the human cytomegalovirus glycoprotein UL142. Biochem. Biophys. Res. Commun. 346 (2006) 175-181
    • (2006) Biochem. Biophys. Res. Commun. , vol.346 , pp. 175-181
    • Chalupny, N.J.1    Rein-Weston, A.2    Dosch, S.3    Cosman, D.4
  • 11
    • 28244435783 scopus 로고    scopus 로고
    • Human cytomegalovirus encodes an MHC class I-like molecule (UL142) that functions to inhibit NK cell lysis
    • Wills M.R., Ashiru O., Reeves M.B., Okecha G., Trowsdale J., Tomasec P., et al. Human cytomegalovirus encodes an MHC class I-like molecule (UL142) that functions to inhibit NK cell lysis. J. Immunol. 175 (2005) 7457-7465
    • (2005) J. Immunol. , vol.175 , pp. 7457-7465
    • Wills, M.R.1    Ashiru, O.2    Reeves, M.B.3    Okecha, G.4    Trowsdale, J.5    Tomasec, P.6
  • 12
    • 33947650773 scopus 로고    scopus 로고
    • The human cytomegalovirus MHC class I homolog UL18 inhibits LIR-1+ but activates LIR-1- NK cells
    • Prod'homme V., Griffin C., Aicheler R.J., Wang E.C., McSharry B.P., Rickards C.R., et al. The human cytomegalovirus MHC class I homolog UL18 inhibits LIR-1+ but activates LIR-1- NK cells. J. Immunol. 178 (2007) 4473-4481
    • (2007) J. Immunol. , vol.178 , pp. 4473-4481
    • Prod'homme, V.1    Griffin, C.2    Aicheler, R.J.3    Wang, E.C.4    McSharry, B.P.5    Rickards, C.R.6
  • 13
    • 0023841944 scopus 로고
    • Human cytomegalovirus encodes a glycoprotein homologous to MHC class-I antigens
    • Beck S., and Barrell B.G. Human cytomegalovirus encodes a glycoprotein homologous to MHC class-I antigens. Nature 331 (1988) 269-272
    • (1988) Nature , vol.331 , pp. 269-272
    • Beck, S.1    Barrell, B.G.2
  • 14
    • 0025053897 scopus 로고
    • A complex between the MHC class I homologue encoded by human cytomegalovirus and beta 2 microglobulin
    • Browne H., Smith G., Beck S., and Minson T. A complex between the MHC class I homologue encoded by human cytomegalovirus and beta 2 microglobulin. Nature 347 (1990) 770-772
    • (1990) Nature , vol.347 , pp. 770-772
    • Browne, H.1    Smith, G.2    Beck, S.3    Minson, T.4
  • 16
    • 0030768392 scopus 로고    scopus 로고
    • A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules
    • Cosman D., Fanger N., Borges L., Kubin M., Chin W., Peterson L., and Hsu M.L. A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. Immunity 7 (1997) 273-282
    • (1997) Immunity , vol.7 , pp. 273-282
    • Cosman, D.1    Fanger, N.2    Borges, L.3    Kubin, M.4    Chin, W.5    Peterson, L.6    Hsu, M.L.7
  • 17
    • 0032543206 scopus 로고    scopus 로고
    • Modulation of natural killer cell cytotoxicity in human cytomegalovirus infection: the role of endogenous class I major histocompatibility complex and a viral class I homolog
    • Leong C.C., Chapman T.L., Bjorkman P.J., Formankova D., Mocarski E.S., Phillips J.H., and Lanier L.L. Modulation of natural killer cell cytotoxicity in human cytomegalovirus infection: the role of endogenous class I major histocompatibility complex and a viral class I homolog. J. Exp. Med. 187 (1998) 1681-1687
    • (1998) J. Exp. Med. , vol.187 , pp. 1681-1687
    • Leong, C.C.1    Chapman, T.L.2    Bjorkman, P.J.3    Formankova, D.4    Mocarski, E.S.5    Phillips, J.H.6    Lanier, L.L.7
  • 18
    • 0030946420 scopus 로고    scopus 로고
    • The class I MHC homologue of human cytomegalovirus inhibits attack by natural killer cells
    • Reyburn H.T., Mandelboim O., Vales-Gomez M., Davis D.M., Pazmany L., and Strominger J.L. The class I MHC homologue of human cytomegalovirus inhibits attack by natural killer cells. Nature 386 (1997) 514-517
    • (1997) Nature , vol.386 , pp. 514-517
    • Reyburn, H.T.1    Mandelboim, O.2    Vales-Gomez, M.3    Davis, D.M.4    Pazmany, L.5    Strominger, J.L.6
  • 19
    • 11144355564 scopus 로고    scopus 로고
    • Specific recognition of the viral protein UL18 by CD85j/LIR-1/ILT2 on CD8+ T cells mediates the non-MHC-restricted lysis of human cytomegalovirus-infected cells
    • Saverino D., Ghiotto F., Merlo A., Bruno S., Battini L., Occhino M., et al. Specific recognition of the viral protein UL18 by CD85j/LIR-1/ILT2 on CD8+ T cells mediates the non-MHC-restricted lysis of human cytomegalovirus-infected cells. J. Immunol. 172 (2004) 5629-5637
    • (2004) J. Immunol. , vol.172 , pp. 5629-5637
    • Saverino, D.1    Ghiotto, F.2    Merlo, A.3    Bruno, S.4    Battini, L.5    Occhino, M.6
  • 20
    • 0032950689 scopus 로고    scopus 로고
    • The leukocyte Ig-like receptor (LIR)-1 for the cytomegalovirus UL18 protein displays a broad specificity for different HLA class I alleles: analysis of LIR-1 + NK cell clones
    • Vitale M., Castriconi R., Parolini S., Pende D., Hsu M.L., Moretta L., et al. The leukocyte Ig-like receptor (LIR)-1 for the cytomegalovirus UL18 protein displays a broad specificity for different HLA class I alleles: analysis of LIR-1 + NK cell clones. Int. Immunol. 11 (1999) 29-35
    • (1999) Int. Immunol. , vol.11 , pp. 29-35
    • Vitale, M.1    Castriconi, R.2    Parolini, S.3    Pende, D.4    Hsu, M.L.5    Moretta, L.6
  • 21
    • 10744229307 scopus 로고    scopus 로고
    • Human cytomegalovirus UL18 alleviated human NK-mediated swine endothelial cell lysis
    • Kim J.S., Choi S.E., Yun I.H., Kim J.Y., Ahn C., Kim S.J., et al. Human cytomegalovirus UL18 alleviated human NK-mediated swine endothelial cell lysis. Biochem. Biophys. Res. Commun. 315 (2004) 144-150
    • (2004) Biochem. Biophys. Res. Commun. , vol.315 , pp. 144-150
    • Kim, J.S.1    Choi, S.E.2    Yun, I.H.3    Kim, J.Y.4    Ahn, C.5    Kim, S.J.6
  • 22
    • 0036223770 scopus 로고    scopus 로고
    • Human cytomegalovirus (HCMV)-infected endothelial cells and macrophages are less susceptible to natural killer lysis independent of the downregulation of classical HLA class I molecules or expression of the HCMV class I homologue, UL18
    • Odeberg J., Cerboni C., Browne H., Karre K., Moller E., Carbone E., and Soderberg-Naucler C. Human cytomegalovirus (HCMV)-infected endothelial cells and macrophages are less susceptible to natural killer lysis independent of the downregulation of classical HLA class I molecules or expression of the HCMV class I homologue, UL18. Scand. J. Immunol. 55 (2002) 149-161
    • (2002) Scand. J. Immunol. , vol.55 , pp. 149-161
    • Odeberg, J.1    Cerboni, C.2    Browne, H.3    Karre, K.4    Moller, E.5    Carbone, E.6    Soderberg-Naucler, C.7
  • 23
    • 33947226776 scopus 로고    scopus 로고
    • Increased expression of leukocyte Ig-like receptor-1 and activating role of UL18 in the response to cytomegalovirus infection
    • Wagner C.S., Riise G.C., Bergstrom T., Karre K., Carbone E., and Berg L. Increased expression of leukocyte Ig-like receptor-1 and activating role of UL18 in the response to cytomegalovirus infection. J. Immunol. 178 (2007) 3536-3543
    • (2007) J. Immunol. , vol.178 , pp. 3536-3543
    • Wagner, C.S.1    Riise, G.C.2    Bergstrom, T.3    Karre, K.4    Carbone, E.5    Berg, L.6
  • 24
    • 0030819308 scopus 로고    scopus 로고
    • A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells
    • Colonna M., Navarro F., Bellon T., Llano M., Garcia P., Samaridis J., et al. A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J. Exp. Med. 186 (1997) 1809-1818
    • (1997) J. Exp. Med. , vol.186 , pp. 1809-1818
    • Colonna, M.1    Navarro, F.2    Bellon, T.3    Llano, M.4    Garcia, P.5    Samaridis, J.6
  • 26
    • 0033229761 scopus 로고    scopus 로고
    • The inhibitory receptor LIR-1 uses a common binding interaction to recognize class I MHC molecules and the viral homolog UL18
    • Chapman T.L., Heikeman A.P., and Bjorkman P.J. The inhibitory receptor LIR-1 uses a common binding interaction to recognize class I MHC molecules and the viral homolog UL18. Immunity 11 (1999) 603-613
    • (1999) Immunity , vol.11 , pp. 603-613
    • Chapman, T.L.1    Heikeman, A.P.2    Bjorkman, P.J.3
  • 27
    • 33748868653 scopus 로고    scopus 로고
    • Human ILT2 receptor associates with murine MHC class I molecules in vivo and impairs T cell function
    • Liang S., Zhang W., and Horuzsko A. Human ILT2 receptor associates with murine MHC class I molecules in vivo and impairs T cell function. Eur. J. Immunol. 36 (2006) 2457-2471
    • (2006) Eur. J. Immunol. , vol.36 , pp. 2457-2471
    • Liang, S.1    Zhang, W.2    Horuzsko, A.3
  • 28
    • 0032945297 scopus 로고    scopus 로고
    • The ILT2(LIR1) and CD94/NKG2A NK cell receptors respectively recognize HLA-G1 and HLA-E molecules co-expressed on target cells
    • Navarro F., Llano M., Bellon T., Colonna M., Geraghty D.E., and Lopez-Botet M. The ILT2(LIR1) and CD94/NKG2A NK cell receptors respectively recognize HLA-G1 and HLA-E molecules co-expressed on target cells. Eur. J. Immunol. 29 (1999) 277-283
    • (1999) Eur. J. Immunol. , vol.29 , pp. 277-283
    • Navarro, F.1    Llano, M.2    Bellon, T.3    Colonna, M.4    Geraghty, D.E.5    Lopez-Botet, M.6
  • 29
    • 0034529752 scopus 로고    scopus 로고
    • Functional characterization of HLA-F and binding of HLA-F tetramers to ILT2 and ILT4 receptors
    • Lepin E.J., Bastin J.M., Allan D.S., Roncador G., Braud V.M., Mason D.Y., et al. Functional characterization of HLA-F and binding of HLA-F tetramers to ILT2 and ILT4 receptors. Eur. J. Immunol. 30 (2000) 3552-3561
    • (2000) Eur. J. Immunol. , vol.30 , pp. 3552-3561
    • Lepin, E.J.1    Bastin, J.M.2    Allan, D.S.3    Roncador, G.4    Braud, V.M.5    Mason, D.Y.6
  • 30
    • 0041381311 scopus 로고    scopus 로고
    • Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor
    • Willcox B.E., Thomas L.M., and Bjorkman P.J. Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor. Nature Immunol. 4 (2003) 913-919
    • (2003) Nature Immunol. , vol.4 , pp. 913-919
    • Willcox, B.E.1    Thomas, L.M.2    Bjorkman, P.J.3
  • 31
    • 33644964890 scopus 로고    scopus 로고
    • Spontaneous mutations in the human CMV HLA class I homologue UL18 affect its binding to the inhibitory receptor LIR-1/ILT2/CD85j
    • Cerboni C., Achour A., Warnmark A., Mousavi-Jazi M., Sandalova T., Hsu M.L., et al. Spontaneous mutations in the human CMV HLA class I homologue UL18 affect its binding to the inhibitory receptor LIR-1/ILT2/CD85j. Eur. J. Immunol. 36 (2006) 732-741
    • (2006) Eur. J. Immunol. , vol.36 , pp. 732-741
    • Cerboni, C.1    Achour, A.2    Warnmark, A.3    Mousavi-Jazi, M.4    Sandalova, T.5    Hsu, M.L.6
  • 32
    • 0033636273 scopus 로고    scopus 로고
    • Crystal structure and ligand binding properties of the D1D2 region of the inhibitory receptor LIR-1 (ILT2)
    • Chapman T.L., Heikema A.P., West Jr. A.P., and Bjorkman P.J. Crystal structure and ligand binding properties of the D1D2 region of the inhibitory receptor LIR-1 (ILT2). Immunity 13 (2000) 727-736
    • (2000) Immunity , vol.13 , pp. 727-736
    • Chapman, T.L.1    Heikema, A.P.2    West Jr., A.P.3    Bjorkman, P.J.4
  • 33
    • 0027098216 scopus 로고
    • Mutant HLA-A201 heavy chains with lowered affinity for beta 2m are transported after growth at reduced temperatures
    • Salter R.D. Mutant HLA-A201 heavy chains with lowered affinity for beta 2m are transported after growth at reduced temperatures. Hum. Immunol. 35 (1992) 40-49
    • (1992) Hum. Immunol. , vol.35 , pp. 40-49
    • Salter, R.D.1
  • 34
    • 1642334894 scopus 로고    scopus 로고
    • Assembly of MHC class I peptide complexes from the perspective of disulfide bond formation
    • Dick T.P. Assembly of MHC class I peptide complexes from the perspective of disulfide bond formation. Cell Mol. Life Sci. 61 (2004) 547-556
    • (2004) Cell Mol. Life Sci. , vol.61 , pp. 547-556
    • Dick, T.P.1
  • 35
    • 0345172216 scopus 로고
    • Intracellular transport blockade caused by disruption of the disulfide bridge in the third external domain of major histocompatibility complex class I antigen
    • Miyazaki J., Appella E., and Ozato K. Intracellular transport blockade caused by disruption of the disulfide bridge in the third external domain of major histocompatibility complex class I antigen. Proc. Natl Acad. Sci. USA 83 (1986) 757-761
    • (1986) Proc. Natl Acad. Sci. USA , vol.83 , pp. 757-761
    • Miyazaki, J.1    Appella, E.2    Ozato, K.3
  • 36
    • 36849156983 scopus 로고
    • Sensitivity of circular dichroism to protein tertiary structure class
    • Manavalan P., and Johnson W.C. Sensitivity of circular dichroism to protein tertiary structure class. Nature 305 (1983) 831-832
    • (1983) Nature , vol.305 , pp. 831-832
    • Manavalan, P.1    Johnson, W.C.2
  • 37
    • 26844481034 scopus 로고    scopus 로고
    • The CD85J/leukocyte inhibitory receptor-1 distinguishes between conformed and beta 2-microglobulin-free HLA-G molecules
    • Gonen-Gross T., Achdout H., Arnon T.I., Gazit R., Stern N., Horejsi V., et al. The CD85J/leukocyte inhibitory receptor-1 distinguishes between conformed and beta 2-microglobulin-free HLA-G molecules. J. Immunol. 175 (2005) 4866-4874
    • (2005) J. Immunol. , vol.175 , pp. 4866-4874
    • Gonen-Gross, T.1    Achdout, H.2    Arnon, T.I.3    Gazit, R.4    Stern, N.5    Horejsi, V.6
  • 38
    • 0035889905 scopus 로고    scopus 로고
    • Leukocyte receptor complex-encoded immunomodulatory receptors show differing specificity for alternative HLA-B27 structures
    • Allen R.L., Raine T., Haude A., Trowsdale J., and Wilson M.J. Leukocyte receptor complex-encoded immunomodulatory receptors show differing specificity for alternative HLA-B27 structures. J. Immunol. 167 (2001) 5543-5547
    • (2001) J. Immunol. , vol.167 , pp. 5543-5547
    • Allen, R.L.1    Raine, T.2    Haude, A.3    Trowsdale, J.4    Wilson, M.J.5
  • 39
    • 0043205005 scopus 로고    scopus 로고
    • Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G
    • Shiroishi M., Tsumoto K., Amano K., Shirakihara Y., Colonna M., Braud V.M., et al. Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G. Proc. Natl Acad. Sci. USA 100 (2003) 8856-8861
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 8856-8861
    • Shiroishi, M.1    Tsumoto, K.2    Amano, K.3    Shirakihara, Y.4    Colonna, M.5    Braud, V.M.6
  • 40
    • 30744473683 scopus 로고    scopus 로고
    • Structural basis of the differential stability and receptor specificity of H-2Db in complex with murine versus human beta2-microglobulin
    • Achour A., Michaelsson J., Harris R.A., Ljunggren H.G., Karre K., Schneider G., and Sandalova T. Structural basis of the differential stability and receptor specificity of H-2Db in complex with murine versus human beta2-microglobulin. J. Mol. Biol. 356 (2006) 382-396
    • (2006) J. Mol. Biol. , vol.356 , pp. 382-396
    • Achour, A.1    Michaelsson, J.2    Harris, R.A.3    Ljunggren, H.G.4    Karre, K.5    Schneider, G.6    Sandalova, T.7
  • 41
    • 4043154821 scopus 로고    scopus 로고
    • Increased expression of the natural killer cell inhibitory receptor CD85j/ILT2 on antigen-specific effector CD8 T cells and its impact on CD8 T-cell function
    • Ince M.N., Harnisch B., Xu Z., Lee S.K., Lange C., Moretta L., et al. Increased expression of the natural killer cell inhibitory receptor CD85j/ILT2 on antigen-specific effector CD8 T cells and its impact on CD8 T-cell function. Immunology 112 (2004) 531-542
    • (2004) Immunology , vol.112 , pp. 531-542
    • Ince, M.N.1    Harnisch, B.2    Xu, Z.3    Lee, S.K.4    Lange, C.5    Moretta, L.6
  • 42
    • 0034292356 scopus 로고    scopus 로고
    • The CD85/LIR-1/ILT2 inhibitory receptor is expressed by all human T lymphocytes and down-regulates their functions
    • Saverino D., Fabbi M., Ghiotto F., Merlo A., Bruno S., Zarcone D., et al. The CD85/LIR-1/ILT2 inhibitory receptor is expressed by all human T lymphocytes and down-regulates their functions. J. Immunol. 165 (2000) 3742-3755
    • (2000) J. Immunol. , vol.165 , pp. 3742-3755
    • Saverino, D.1    Fabbi, M.2    Ghiotto, F.3    Merlo, A.4    Bruno, S.5    Zarcone, D.6
  • 43
    • 0036136334 scopus 로고    scopus 로고
    • Dual effect of CD85/leukocyte Ig-like receptor-1/Ig-like transcript 2 and CD152 (CTLA-4) on cytokine production by antigen-stimulated human T cells
    • Saverino D., Merlo A., Bruno S., Pistoia V., Grossi C.E., and Ciccone E. Dual effect of CD85/leukocyte Ig-like receptor-1/Ig-like transcript 2 and CD152 (CTLA-4) on cytokine production by antigen-stimulated human T cells. J. Immunol. 168 (2002) 207-215
    • (2002) J. Immunol. , vol.168 , pp. 207-215
    • Saverino, D.1    Merlo, A.2    Bruno, S.3    Pistoia, V.4    Grossi, C.E.5    Ciccone, E.6
  • 44
    • 0033636273 scopus 로고    scopus 로고
    • Crystal structure and ligand binding properties of the D1D2 region of the inhibitory receptor LIR-1 (ILT2)
    • Chapman T.L., Heikema A.P., West Jr. A.P., and Bjorkman P.J. Crystal structure and ligand binding properties of the D1D2 region of the inhibitory receptor LIR-1 (ILT2). Immunity 13 (2000) 727-736
    • (2000) Immunity , vol.13 , pp. 727-736
    • Chapman, T.L.1    Heikema, A.P.2    West Jr., A.P.3    Bjorkman, P.J.4
  • 45
    • 0035877056 scopus 로고    scopus 로고
    • MHC class I recognition by NK receptors in the Ly49 family is strongly influenced by the beta 2-microglobulin subunit
    • Michaelsson J., Achour A., Rolle A., and Karre K. MHC class I recognition by NK receptors in the Ly49 family is strongly influenced by the beta 2-microglobulin subunit. J. Immunol. 166 (2001) 7327-7334
    • (2001) J. Immunol. , vol.166 , pp. 7327-7334
    • Michaelsson, J.1    Achour, A.2    Rolle, A.3    Karre, K.4
  • 46
    • 0031473847 scopus 로고    scopus 로고
    • SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling
    • Guex N., and Peitsch M.C. SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis 18 (1997) 2714-2723
    • (1997) Electrophoresis , vol.18 , pp. 2714-2723
    • Guex, N.1    Peitsch, M.C.2
  • 48
    • 0029986943 scopus 로고    scopus 로고
    • Characterization of a cell line, NKL, derived from an aggressive human natural killer cell leukemia
    • Robertson M.J., Cochran K.J., Cameron C., Le J.M., Tantravahi R., and Ritz J. Characterization of a cell line, NKL, derived from an aggressive human natural killer cell leukemia. Exp. Hematol. 24 (1996) 406-415
    • (1996) Exp. Hematol. , vol.24 , pp. 406-415
    • Robertson, M.J.1    Cochran, K.J.2    Cameron, C.3    Le, J.M.4    Tantravahi, R.5    Ritz, J.6
  • 50
    • 0024448151 scopus 로고
    • Calculation of protein extinction coefficients from amino acid sequence data
    • Gill S.C., and von Hippel P.H. Calculation of protein extinction coefficients from amino acid sequence data. Anal. Biochem. 182 (1989) 319-326
    • (1989) Anal. Biochem. , vol.182 , pp. 319-326
    • Gill, S.C.1    von Hippel, P.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.