메뉴 건너뛰기




Volumn , Issue , 2007, Pages 613-631

Ricin and Abrin Poisoning

Author keywords

A chain and ricin catalytic activity; Abrin poison management; Ricin and abrin poisoning; Ricin endocytosis; Ricin exposure toxicokinetics

Indexed keywords


EID: 34648869481     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470060032.ch27     Document Type: Chapter
Times cited : (5)

References (181)
  • 1
    • 0030754431 scopus 로고    scopus 로고
    • Ingestion of castor oil plant seeds
    • Aplin PJ and Eliseo T (1997). Ingestion of castor oil plant seeds. Med J Aust, 167, 260-261.
    • (1997) Med J Aust , vol.167 , pp. 260-261
    • Aplin, P.J.1    Eliseo, T.2
  • 2
    • 0034737432 scopus 로고    scopus 로고
    • Ribosome-mediated folding of partially unfolded ricin A-chain
    • Argent RH, Parrott AM, Day PJ et al. (2000) Ribosome-mediated folding of partially unfolded ricin A-chain. J Biol Chem, 275, 9263-9269.
    • (2000) J Biol Chem , vol.275 , pp. 9263-9269
    • Argent, R.H.1    Parrott, A.M.2    Day, P.J.3
  • 3
    • 0029083773 scopus 로고
    • Rapid endocytosis coupled to exocytosis in adrenal chromaffin cells involves Ca2+, GTP and dynamin but not clathrin
    • Artalejo CR, Henley JR, McNiven MA et al. (1995) Rapid endocytosis coupled to exocytosis in adrenal chromaffin cells involves Ca2+, GTP and dynamin but not clathrin. Proc Natl Acad Sci USA, 92, 8328-8332.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8328-8332
    • Artalejo, C.R.1    Henley, J.R.2    McNiven, M.A.3
  • 4
    • 0015962910 scopus 로고
    • Ricin: the toxic protein of castor oil seeds
    • Balint GA (1974) Ricin: the toxic protein of castor oil seeds. Toxicology, 2, 77-102.
    • (1974) Toxicology , vol.2 , pp. 77-102
    • Balint, G.A.1
  • 5
    • 0029907473 scopus 로고    scopus 로고
    • Decreases in levels of serum fibronectin predict the severity of vascular leak syndrome in patients treated with ricin A-chain containing immunotoxins
    • Baluna R, Sausville EA, Stone MJ et al. (1996) Decreases in levels of serum fibronectin predict the severity of vascular leak syndrome in patients treated with ricin A-chain containing immunotoxins. Clin Cancer Res, 2, 1705-1712.
    • (1996) Clin Cancer Res , vol.2 , pp. 1705-1712
    • Baluna, R.1    Sausville, E.A.2    Stone, M.J.3
  • 6
    • 0033616693 scopus 로고    scopus 로고
    • Evidence for a structural motif in toxins and interleukin-2 that may be responsible for binding to endothelial cells and initiating vascular leak syndrome
    • Baluna R, Rizo J, Gordon BE et al. (1999) Evidence for a structural motif in toxins and interleukin-2 that may be responsible for binding to endothelial cells and initiating vascular leak syndrome. Proc Natl Acad Sci USA, 96, 3957-3962.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3957-3962
    • Baluna, R.1    Rizo, J.2    Gordon, B.E.3
  • 7
    • 0033607003 scopus 로고    scopus 로고
    • Placement of protein and RNA structures into a 5 Å-resolution map of the 50S ribosomal subunit
    • Ban N, Nissen P, Hansen J et al. (1999) Placement of protein and RNA structures into a 5 Å-resolution map of the 50S ribosomal subunit. Nature, 400, 841-847.
    • (1999) Nature , vol.400 , pp. 841-847
    • Ban, N.1    Nissen, P.2    Hansen, J.3
  • 9
    • 3042515159 scopus 로고    scopus 로고
    • Cytotoxicity and toxicity to animals and humans of ribosome-inactivating proteins
    • Battelli MG (2004) Cytotoxicity and toxicity to animals and humans of ribosome-inactivating proteins. Mini Rev Med Chem, 4, 513-521.
    • (2004) Mini Rev Med Chem , vol.4 , pp. 513-521
    • Battelli, M.G.1
  • 10
    • 0023202680 scopus 로고
    • The Kupffer cell is the first target in ricin-independent hepatitis
    • Bingen A, Creppy EE, Gut JP et al. (1987) The Kupffer cell is the first target in ricin-independent hepatitis. J Submicrosc Cytol, 19, 247-256.
    • (1987) J Submicrosc Cytol , vol.19 , pp. 247-256
    • Bingen, A.1    Creppy, E.E.2    Gut, J.P.3
  • 11
    • 0142017307 scopus 로고
    • Report of cases of poisoning by fruit of Ricinus communis
    • Bispham WN (1903) Report of cases of poisoning by fruit of Ricinus communis. Am J Med Sci, 12, 319-321.
    • (1903) Am J Med Sci , vol.12 , pp. 319-321
    • Bispham, W.N.1
  • 12
    • 0030886158 scopus 로고    scopus 로고
    • Ultrastructure of rat lung following inhalation of ricin aerosol
    • Brown RFR and White DE (1997) Ultrastructure of rat lung following inhalation of ricin aerosol. Int J Exp Pathol, 78, 267-276.
    • (1997) Int J Exp Pathol , vol.78 , pp. 267-276
    • Brown, R.F.R.1    White, D.E.2
  • 13
    • 0033452609 scopus 로고    scopus 로고
    • Biological warfare agents as threats to potable water
    • Burrows WD and Renner SE (1999) Biological warfare agents as threats to potable water. Environ Health Perspect, 107, 975-984.
    • (1999) Environ Health Perspect , vol.107 , pp. 975-984
    • Burrows, W.D.1    Renner, S.E.2
  • 14
    • 0020993866 scopus 로고
    • Ricin and Ricinus communis agglutinin subunits are all derived from a single-size polypeptide precursor
    • Butterworth AG and Lord JM (1983) Ricin and Ricinus communis agglutinin subunits are all derived from a single-size polypeptide precursor. Eur J Biochem, 137, 57-65.
    • (1983) Eur J Biochem , vol.137 , pp. 57-65
    • Butterworth, A.G.1    Lord, J.M.2
  • 15
    • 84890160340 scopus 로고
    • The Practice of Medicine in the Tropics
    • London, UK: Henry Frowde and Hodder & Stoughton
    • ByamWand Archibald RG (eds) (1921). The Practice of Medicine in the Tropics. London, UK: Henry Frowde and Hodder & Stoughton.
    • (1921)
    • ByamWand Archibald, R.G.1
  • 16
    • 0017396349 scopus 로고
    • Differential ricin sensitivity of rat liver and wheat germ ribosomes in polyuridylic acid translation
    • Cawley DB, Hedblom ML, Hoffman EJ et al. (1977) Differential ricin sensitivity of rat liver and wheat germ ribosomes in polyuridylic acid translation. Arch Biochem Biophys, 182, 690-695.
    • (1977) Arch Biochem Biophys , vol.182 , pp. 690-695
    • Cawley, D.B.1    Hedblom, M.L.2    Hoffman, E.J.3
  • 17
    • 0027195206 scopus 로고
    • Mutagenesis and kinetic analysis of the active site Glu177 of ricin A-chain
    • Chaddock JA and Roberts LM (1993) Mutagenesis and kinetic analysis of the active site Glu177 of ricin A-chain. Protein Eng, 6, 425-431.
    • (1993) Protein Eng , vol.6 , pp. 425-431
    • Chaddock, J.A.1    Roberts, L.M.2
  • 19
    • 0037012521 scopus 로고    scopus 로고
    • Retrograde transport of protein toxins under conditions of COP1 dysfunction
    • Chen A, Hu T, Mikoryak C et al. (2002) Retrograde transport of protein toxins under conditions of COP1 dysfunction. Biochim Biophys Acta, 1589, 124-139.
    • (2002) Biochim Biophys Acta , vol.1589 , pp. 124-139
    • Chen, A.1    Hu, T.2    Mikoryak, C.3
  • 20
    • 0019430546 scopus 로고
    • Time dependency of ascorbate compound administration to alter the mean survival time of abrin intoxication
    • Clark CE,Keplinger JL, Riddle MR et al. (1981) Time dependency of ascorbate compound administration to alter the mean survival time of abrin intoxication. Fed Proc Fed Am Soc Exp Biol, 40, 865.
    • (1981) Fed Proc Fed Am Soc Exp Biol , vol.40 , pp. 865
    • Clark, C.E.1    Keplinger, J.L.2    Riddle, M.R.3
  • 21
    • 0028181745 scopus 로고
    • Coatomer interaction with di-lysine endoplasmic reticulum retention motifs
    • Cosson P and Letourneur F (1994) Coatomer interaction with di-lysine endoplasmic reticulum retention motifs. Science, 263, 1629-1631.
    • (1994) Science , vol.263 , pp. 1629-1631
    • Cosson, P.1    Letourneur, F.2
  • 22
    • 0030760897 scopus 로고    scopus 로고
    • Coatomer (COP1)-coated vesicles: role in intracellular transport and protein sorting
    • Cosson P and Letourneur F (1997) Coatomer (COP1)-coated vesicles: role in intracellular transport and protein sorting. Curr Opin Cell Biol, 9, 484-487.
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 484-487
    • Cosson, P.1    Letourneur, F.2
  • 23
    • 0019158721 scopus 로고
    • Georgi Markov-death in a pellet
    • Crompton R and Gall D (1980) Georgi Markov-death in a pellet. Med Legal J, 48, 51-62.
    • (1980) Med Legal J , vol.48 , pp. 51-62
    • Crompton, R.1    Gall, D.2
  • 24
    • 0029134736 scopus 로고
    • Clathrin-independent pinocytosis is induced in cells overexpressing a temperature-sensitive mutant of dynamin
    • Damke H, Baba T, van der Bliek AM et al. (1995) Clathrin-independent pinocytosis is induced in cells overexpressing a temperature-sensitive mutant of dynamin. J Cell Biol, 131, 69-80.
    • (1995) J Cell Biol , vol.131 , pp. 69-80
    • Damke, H.1    Baba, T.2    Van Der Bliek, A.M.3
  • 25
    • 0017944776 scopus 로고
    • Abrus precatorius (rosary pea). The most common lethal plant poison
    • Davis JH (1978) Abrus precatorius (rosary pea). The most common lethal plant poison. J Fla Med Assoc, 65, 188-191.
    • (1978) J Fla Med Assoc , vol.65 , pp. 188-191
    • Davis, J.H.1
  • 26
    • 0035831558 scopus 로고    scopus 로고
    • An interaction between ricin and calreticulin that may have implications for toxin trafficking
    • Day PJ, Owens SR, Wesche J et al. (2001) An interaction between ricin and calreticulin that may have implications for toxin trafficking. J Biol Chem, 276, 7202-7208.
    • (2001) J Biol Chem , vol.276 , pp. 7202-7208
    • Day, P.J.1    Owens, S.R.2    Wesche, J.3
  • 27
    • 0037066109 scopus 로고    scopus 로고
    • The low lysine content of ricin A chain reduces the risk of proteolytic degradation after translocation from the endoplasmic reticulum to the cytosol
    • Deeks ED, Cook JP, Day PJ et al. (2002) The low lysine content of ricin A chain reduces the risk of proteolytic degradation after translocation from the endoplasmic reticulum to the cytosol. Biochemistry, 41, 3405-3413.
    • (2002) Biochemistry , vol.41 , pp. 3405-3413
    • Deeks, E.D.1    Cook, J.P.2    Day, P.J.3
  • 28
    • 80055005222 scopus 로고    scopus 로고
    • A case of accidental ricin poisoning
    • Despott E and Cachia MJ (2004) A case of accidental ricin poisoning. Malta Med J, 16, 39-41.
    • (2004) Malta Med J , vol.16 , pp. 39-41
    • Despott, E.1    Cachia, M.J.2
  • 30
    • 0023219950 scopus 로고
    • N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomers
    • Endo Y and Tsurugi K (1987) N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomers. J Biol Chem, 262, 8128-8130.
    • (1987) J Biol Chem , vol.262 , pp. 8128-8130
    • Endo, Y.1    Tsurugi, K.2
  • 31
    • 0023947126 scopus 로고
    • The RNA Nglycosidase activity of ricin A-chain. The characteristics of the enzymatic activity of ricin A-chain with ribosomes and with rRNA
    • Endo Y and Tsurugi K (1988) The RNA Nglycosidase activity of ricin A-chain. The characteristics of the enzymatic activity of ricin A-chain with ribosomes and with rRNA. J Biol Chem, 263, 8735-8739.
    • (1988) J Biol Chem , vol.263 , pp. 8735-8739
    • Endo, Y.1    Tsurugi, K.2
  • 32
    • 0031037004 scopus 로고    scopus 로고
    • A phase-I study of an anti-CD25 ricin A-chain immunotoxin (RFT5-SMPT-dgA) in patients with refractory Hodgkin's lymphoma
    • Engert A, Diehl V, Schnell R et al. (1997) A phase-I study of an anti-CD25 ricin A-chain immunotoxin (RFT5-SMPT-dgA) in patients with refractory Hodgkin's lymphoma. Blood, 89, 403-410.
    • (1997) Blood , vol.89 , pp. 403-410
    • Engert, A.1    Diehl, V.2    Schnell, R.3
  • 33
    • 0035191807 scopus 로고    scopus 로고
    • Poisoning due to Abrus precatorius (jequirity bean)
    • Fernando C (2001) Poisoning due to Abrus precatorius (jequirity bean). Anaesthesia, 56, 1178-1180.
    • (2001) Anaesthesia , vol.56 , pp. 1178-1180
    • Fernando, C.1
  • 34
    • 0028829735 scopus 로고
    • Expression of functional ricin B chain using the baculovirus system
    • Ferrini J-B, Martin M, Taupiac M-P et al. (1995) Expression of functional ricin B chain using the baculovirus system. Eur J Biochem, 233, 772-777.
    • (1995) Eur J Biochem , vol.233 , pp. 772-777
    • Ferrini, J.-B.1    Martin, M.2    Taupiac, M.-P.3
  • 35
    • 0004897756 scopus 로고
    • Endemic asthma due to castor bean dust
    • Figley KD and Elrod RH (1928) Endemic asthma due to castor bean dust. JAMA, 90, 79-82.
    • (1928) JAMA , vol.90 , pp. 79-82
    • Figley, K.D.1    Elrod, R.H.2
  • 36
    • 0026500729 scopus 로고
    • Sub-lethal poisoning by self-injection with ricin
    • Fine DR, Shepherd HA, Griffiths GD et al. (1992). Sub-lethal poisoning by self-injection with ricin. Med Sci Law, 32, 70-72.
    • (1992) Med Sci Law , vol.32 , pp. 70-72
    • Fine, D.R.1    Shepherd, H.A.2    Griffiths, G.D.3
  • 37
    • 0017142394 scopus 로고
    • Toxicity, distribution and elimination of the cancerostatic lectins abrin and ricin after parental injection into mice
    • Fodstad Ø, Olsnes S and Pihl A (1976). Toxicity, distribution and elimination of the cancerostatic lectins abrin and ricin after parental injection into mice. Br J Cancer, 34, 418-425.
    • (1976) Br J Cancer , vol.34 , pp. 418-425
    • Fodstad Ø1    Olsnes, S.2    Pihl, A.3
  • 39
    • 0021369395 scopus 로고
    • Phase I study of the plant protein ricin
    • Fodstad Ø, Kvalheim G, Godal A et al. (1984) Phase I study of the plant protein ricin. Cancer Res, 44, 862-865.
    • (1984) Cancer Res , vol.44 , pp. 862-865
    • Fodstad Ø1    Kvalheim, G.2    Godal, A.3
  • 40
    • 0021985323 scopus 로고
    • The use of anti-ricin antibodies to protect mice intoxicated with ricin
    • Foxwell BMJ, Detre SI, Donovan TA et al. (1985) The use of anti-ricin antibodies to protect mice intoxicated with ricin. Toxicology, 34, 79-88.
    • (1985) Toxicology , vol.34 , pp. 79-88
    • Foxwell, B.M.J.1    Detre, S.I.2    Donovan, T.A.3
  • 41
    • 0025224121 scopus 로고
    • Role of arginine 180 and glutamic acid 177 of ricin toxin A chain in enzymatic inactivation of ribosomes
    • Frankel A,Welsh P, Richardson J et al. (1990) Role of arginine 180 and glutamic acid 177 of ricin toxin A chain in enzymatic inactivation of ribosomes. Mol Cell Biol, 10, 6257-6263.
    • (1990) Mol Cell Biol , vol.10 , pp. 6257-6263
    • Frankel, A.1    Welsh, P.2    Richardson, J.3
  • 42
    • 0002954612 scopus 로고    scopus 로고
    • Ricin toxin
    • FR Siddell, ET Takafuji and DR Franz, eds, Washington, DC, USA: Office of the Surgeon General at TMM Publications
    • Franz DR and Jaax NK (1997). Ricin toxin. In: Medical Aspects of Chemical and Biological Warfare (FR Siddell, ET Takafuji and DR Franz, eds), pp. 631-642. Washington, DC, USA: Office of the Surgeon General at TMM Publications.
    • (1997) Medical Aspects of Chemical and Biological Warfare , pp. 631-642
    • Franz, D.R.1    Jaax, N.K.2
  • 43
    • 0032486270 scopus 로고    scopus 로고
    • Free ricinA chain, proricin and native toxin have different cellular fates when expressed in tobacco protoplasts
    • Frigerio L,Vitale A, Lord JM et al. (1998) Free ricinA chain, proricin and native toxin have different cellular fates when expressed in tobacco protoplasts. J Biol Chem, 273, 14194-14199.
    • (1998) J Biol Chem , vol.273 , pp. 14194-14199
    • Frigerio, L.1    Vitale, A.2    Lord, J.M.3
  • 44
    • 0034965672 scopus 로고    scopus 로고
    • The internal propeptide of the ricin precursor carries a sequence-specific determinant for vacuolar sorting
    • Frigerio L, Jolliffe NA, Di Cola A et al. (2001) The internal propeptide of the ricin precursor carries a sequence-specific determinant for vacuolar sorting. Plant Physiol, 126, 167-175.
    • (2001) Plant Physiol , vol.126 , pp. 167-175
    • Frigerio, L.1    Jolliffe, N.A.2    Di Cola, A.3
  • 46
    • 0032563568 scopus 로고    scopus 로고
    • An endocytosed TGN38 chimeric protein is delivered to the TGN after trafficking through the endocytic recycling compartment in CHO cells
    • Ghosh RN, Mallet WG, Soe TT et al. (1998) An endocytosed TGN38 chimeric protein is delivered to the TGN after trafficking through the endocytic recycling compartment in CHO cells. J Cell Biol, 142, 923-936.
    • (1998) J Cell Biol , vol.142 , pp. 923-936
    • Ghosh, R.N.1    Mallet, W.G.2    Soe, T.T.3
  • 47
    • 0020073392 scopus 로고
    • Bacterial toxins: a table of lethal amounts
    • Gill DM (1982) Bacterial toxins: a table of lethal amounts. Microbiol Rev, 46, 86-94.
    • (1982) Microbiol Rev , vol.46 , pp. 86-94
    • Gill, D.M.1
  • 48
    • 0033224214 scopus 로고    scopus 로고
    • Evidence for a COP1-independent transport route from Golgi complex to the endoplasmic reticulum
    • Girod A, Storrie B, Simpson JC et al. (1999) Evidence for a COP1-independent transport route from Golgi complex to the endoplasmic reticulum. Nat Cell Biol, 1, 423-430.
    • (1999) Nat Cell Biol , vol.1 , pp. 423-430
    • Girod, A.1    Storrie, B.2    Simpson, J.C.3
  • 49
    • 0019858738 scopus 로고
    • Radioimmunoassays of abrin and ricin in blood
    • Godal A, Olsnes S and Pihl A (1981) Radioimmunoassays of abrin and ricin in blood. J Toxicol Environ Health, 8, 409-417.
    • (1981) J Toxicol Environ Health , vol.8 , pp. 409-417
    • Godal, A.1    Olsnes, S.2    Pihl, A.3
  • 50
    • 0003397765 scopus 로고
    • Toxicology of the Eye. Effects on the Eyes and Visual System from Chemicals, Drugs, Metals and Minerals, Plants, Toxins and Venoms; also Systemic Side Effects from Eye Medications, Fourth Edition
    • Springfield, IL, USA: Charles C. Thomas
    • Grant WM and Schuman JS (1993). Toxicology of the Eye. Effects on the Eyes and Visual System from Chemicals, Drugs, Metals and Minerals, Plants, Toxins and Venoms; also Systemic Side Effects from Eye Medications, Fourth Edition. Springfield, IL, USA: Charles C. Thomas.
    • (1993)
    • Grant, W.M.1    Schuman, J.S.2
  • 51
    • 0022444671 scopus 로고
    • Identification and quantification of ricin toxin in animal tissues using ELISA
    • Griffiths GD, Newman H and Gee DJ (1986) Identification and quantification of ricin toxin in animal tissues using ELISA. J Forens Sci Soc, 26, 349-358.
    • (1986) J Forens Sci Soc , vol.26 , pp. 349-358
    • Griffiths, G.D.1    Newman, H.2    Gee, D.J.3
  • 52
    • 0028358721 scopus 로고
    • Examination of the toxicity of several protein toxins of plant origin using bovine pulmonary endothelial cells
    • Griffiths GD, Lindsay CD and Upshall DG (1994) Examination of the toxicity of several protein toxins of plant origin using bovine pulmonary endothelial cells. Toxicology, 90, 11-27.
    • (1994) Toxicology , vol.90 , pp. 11-27
    • Griffiths, G.D.1    Lindsay, C.D.2    Upshall, D.G.3
  • 53
    • 0000876903 scopus 로고
    • Inhalation toxicology and histopathology of ricin and abrin toxins
    • Griffiths GD, Rice P, Allenby AC et al. (1995a) Inhalation toxicology and histopathology of ricin and abrin toxins. Inhal Toxicol, 7, 269-288.
    • (1995) Inhal Toxicol , vol.7 , pp. 269-288
    • Griffiths, G.D.1    Rice, P.2    Allenby, A.C.3
  • 54
    • 0028927950 scopus 로고
    • Protection against inhalation toxicity of ricin and abrin by immunisation
    • Griffiths GD, Lindsay CD, Allenby AC et al. (1995b) Protection against inhalation toxicity of ricin and abrin by immunisation. Human Exp Toxicol, 14, 155-164.
    • (1995) Human Exp Toxicol , vol.14 , pp. 155-164
    • Griffiths, G.D.1    Lindsay, C.D.2    Allenby, A.C.3
  • 55
    • 0030733914 scopus 로고    scopus 로고
    • Liposomally-encapsulated ricin toxoid vaccine delivered intratracheally elicits a good immune response and protects a lethal pulmonary dose of ricin toxin
    • Griffiths GD, Bailey SC, Hambrook JL et al. (1997) Liposomally-encapsulated ricin toxoid vaccine delivered intratracheally elicits a good immune response and protects a lethal pulmonary dose of ricin toxin. Vaccine, 15, 1933-1939.
    • (1997) Vaccine , vol.15 , pp. 1933-1939
    • Griffiths, G.D.1    Bailey, S.C.2    Hambrook, J.L.3
  • 56
    • 0032033575 scopus 로고    scopus 로고
    • Local and systemic responses against ricin toxin promoted by toxoid or peptide vaccines alone or in liposomal formulations
    • Griffiths GD, Bailey SC, Hambrook JL et al. (1998) Local and systemic responses against ricin toxin promoted by toxoid or peptide vaccines alone or in liposomal formulations. Vaccine, 16, 530-535.
    • (1998) Vaccine , vol.16 , pp. 530-535
    • Griffiths, G.D.1    Bailey, S.C.2    Hambrook, J.L.3
  • 57
    • 0033523046 scopus 로고    scopus 로고
    • Comparison of the quality of protection elicited by toxoid and peptide liposomal vaccine formulations against ricin as assessed by markers of inflammation
    • Griffiths GD, Phillips GJ, and Bailey SC (1999) Comparison of the quality of protection elicited by toxoid and peptide liposomal vaccine formulations against ricin as assessed by markers of inflammation. Vaccine, 17, 2562-2568.
    • (1999) Vaccine , vol.17 , pp. 2562-2568
    • Griffiths, G.D.1    Phillips, G.J.2    Bailey, S.C.3
  • 58
    • 0014256251 scopus 로고
    • A propos d'une curieuse intoxication par des grains de chapelet (abrus precatorius)
    • Guggisberg M (1968). A propos d'une curieuse intoxication par des grains de chapelet (abrus precatorius). Rev Med Suisse Romande, 88, 206-208.
    • (1968) Rev Med Suisse Romande , vol.88 , pp. 206-208
    • Guggisberg, M.1
  • 59
    • 0028884598 scopus 로고
    • Adjuvants for human vaccines-current status, problems and future prospects
    • Gupta RK and Siber GR (1995) Adjuvants for human vaccines-current status, problems and future prospects. Vaccine, 13, 1263-1276.
    • (1995) Vaccine , vol.13 , pp. 1263-1276
    • Gupta, R.K.1    Siber, G.R.2
  • 60
    • 3042655888 scopus 로고
    • Ricin inhibition of in vitro protein synthesis by plant ribosomes
    • Harley SM and Beevers H (1982) Ricin inhibition of in vitro protein synthesis by plant ribosomes. Proc Nat Acad Sci USA, 79, 5935-5938.
    • (1982) Proc Nat Acad Sci USA , vol.79 , pp. 5935-5938
    • Harley, S.M.1    Beevers, H.2
  • 61
    • 0000697061 scopus 로고
    • In vitro endoproteolytic cleavage of castor bean lectin precursors
    • Harley SM and Lord JM (1985) In vitro endoproteolytic cleavage of castor bean lectin precursors. Plant Sci, 41, 111-116.
    • (1985) Plant Sci , vol.41 , pp. 111-116
    • Harley, S.M.1    Lord, J.M.2
  • 62
    • 0006696222 scopus 로고
    • Hazards to health. Jequirity-bean poisoning
    • Hart M (1963) Hazards to health. Jequirity-bean poisoning. New Engl J Med, 268, 885-886.
    • (1963) New Engl J Med , vol.268 , pp. 885-886
    • Hart, M.1
  • 63
    • 0030207043 scopus 로고    scopus 로고
    • The structure and function of ribosome inactivating proteins
    • Hartley MR, Chaddock JA and Bonness MS (1996) The structure and function of ribosome inactivating proteins. Trends Plant Sci, 1, 254-259.
    • (1996) Trends Plant Sci , vol.1 , pp. 254-259
    • Hartley, M.R.1    Chaddock, J.A.2    Bonness, M.S.3
  • 64
    • 0030886889 scopus 로고    scopus 로고
    • Accumulating evidence suggests that several AB-toxins subvert the endoplasmic reticulum-associated protein degradation pathway to enter target cells
    • Hazes B and Read RJ (1997) Accumulating evidence suggests that several AB-toxins subvert the endoplasmic reticulum-associated protein degradation pathway to enter target cells. Biochemistry, 36, 11051-11054.
    • (1997) Biochemistry , vol.36 , pp. 11051-11054
    • Hazes, B.1    Read, R.J.2
  • 65
    • 0027292228 scopus 로고
    • Effects of mutant rat dynamin on endocytosis
    • Herskovits JS, Burgess CC, Obar RA et al. (1993) Effects of mutant rat dynamin on endocytosis. J Cell Biol, 122, 565-578.
    • (1993) J Cell Biol , vol.122 , pp. 565-578
    • Herskovits, J.S.1    Burgess, C.C.2    Obar, R.A.3
  • 66
    • 0027289275 scopus 로고
    • Protection of mice from inhaled ricin by vaccination with ricin or by passive treatment with heterologous antibody
    • Hewetson JF, Rivera VR, Creasia DA et al. (1993) Protection of mice from inhaled ricin by vaccination with ricin or by passive treatment with heterologous antibody. Vaccine, 11, 743-746.
    • (1993) Vaccine , vol.11 , pp. 743-746
    • Hewetson, J.F.1    Rivera, V.R.2    Creasia, D.A.3
  • 67
    • 0029613757 scopus 로고
    • A formalinized toxoid for protection of mice from inhaled ricin
    • Hewetson JF, Rivera VP, Lemley PV et al. (1995) A formalinized toxoid for protection of mice from inhaled ricin. Vaccine Res, 4, 179-187.
    • (1995) Vaccine Res , vol.4 , pp. 179-187
    • Hewetson, J.F.1    Rivera, V.P.2    Lemley, P.V.3
  • 68
    • 0020455487 scopus 로고
    • Protection of mice from ricin poisoning by treatment with antibodies directed against ricin
    • Houston LL (1982) Protection of mice from ricin poisoning by treatment with antibodies directed against ricin. J Toxicol Clin Toxicol, 19, 385-389.
    • (1982) J Toxicol Clin Toxicol , vol.19 , pp. 385-389
    • Houston, L.L.1
  • 69
    • 0029976919 scopus 로고    scopus 로고
    • Morphology of ricin and abrin exposed endothelial cells is consistent with apoptotic cell death
    • Hughes JN, Lindsay CD and Griffiths GD (1996) Morphology of ricin and abrin exposed endothelial cells is consistent with apoptotic cell death. Human Exp Toxicol, 15, 443-451.
    • (1996) Human Exp Toxicol , vol.15 , pp. 443-451
    • Hughes, J.N.1    Lindsay, C.D.2    Griffiths, G.D.3
  • 70
    • 84965322720 scopus 로고
    • Poisoning by castor oil seeds
    • Hutchinson LTR (1900) Poisoning by castor oil seeds. Br Med J, 1, 1155-1156.
    • (1900) Br Med J , vol.1 , pp. 1155-1156
    • Hutchinson, L.T.R.1
  • 71
    • 0013937582 scopus 로고
    • Accidental poisoning in children with particular reference to castor beans
    • Ingle VN, Kale VG and Talwalker YB (1966) Accidental poisoning in children with particular reference to castor beans. Ind J Pediatr, 33, 237-240.
    • (1966) Ind J Pediatr , vol.33 , pp. 237-240
    • Ingle, V.N.1    Kale, V.G.2    Talwalker, Y.B.3
  • 72
    • 0026656484 scopus 로고
    • Biochemical studies on oral toxicity of ricin. IV. A fate of orally administered ricin in rats
    • Ishiguro M, Tanabe S, Matori Y et al. (1992) Biochemical studies on oral toxicity of ricin. IV. A fate of orally administered ricin in rats. J Pharmacobiodyn, 15, 147-156.
    • (1992) J Pharmacobiodyn , vol.15 , pp. 147-156
    • Ishiguro, M.1    Tanabe, S.2    Matori, Y.3
  • 73
    • 0035150144 scopus 로고    scopus 로고
    • Endosome to Golgi transport of ricin is independent of clathrin and of the Rab9-and Rab11-GTPases
    • Iversen T-G, Skretting G, Llorente A et al. (2001) Endosome to Golgi transport of ricin is independent of clathrin and of the Rab9-and Rab11-GTPases. Mol Cell Biol, 12, 2099-2107.
    • (2001) Mol Cell Biol , vol.12 , pp. 2099-2107
    • Iversen, T.-G.1    Skretting, G.2    Llorente, A.3
  • 74
    • 17144412110 scopus 로고    scopus 로고
    • Quantification of ricinine in rat and human urine: a biomarker for ricin exposure
    • Johnson RC, Lemire SW, Woolfitt AR et al. (2005) Quantification of ricinine in rat and human urine: a biomarker for ricin exposure. J Anal Toxicol, 29, 149-155.
    • (2005) J Anal Toxicol , vol.29 , pp. 149-155
    • Johnson, R.C.1    Lemire, S.W.2    Woolfitt, A.R.3
  • 75
    • 0037351492 scopus 로고    scopus 로고
    • The position of the proricin vacuolar targeting signal is functionally important
    • Jolliffe NA, Ceriotti A, Frigerio L et al. (2003) The position of the proricin vacuolar targeting signal is functionally important. Plant Mol Biol, 51, 631-641.
    • (2003) Plant Mol Biol , vol.51 , pp. 631-641
    • Jolliffe, N.A.1    Ceriotti, A.2    Frigerio, L.3
  • 76
    • 0025253555 scopus 로고
    • Longlasting contact urticaria. Type I and type IV allergy from castor bean and a hypothesis of systemic IgE-mediated allergic dermatitis
    • Kanerva L, Estlander T and Jolanki R (1990) Longlasting contact urticaria. Type I and type IV allergy from castor bean and a hypothesis of systemic IgE-mediated allergic dermatitis. Dermatol Clin, 8, 181-188.
    • (1990) Dermatol Clin , vol.8 , pp. 181-188
    • Kanerva, L.1    Estlander, T.2    Jolanki, R.3
  • 77
    • 4243367165 scopus 로고
    • Ricinussamen-Vergiftung von Schulkindern
    • KaszSs T and Papp G (1960) Ricinussamen-Vergiftung von Schulkindern. Arch Toxikol, 18, 145-150.
    • (1960) Arch Toxikol , vol.18 , pp. 145-150
    • Kaszás, T.1    Papp, G.2
  • 79
    • 0037154847 scopus 로고    scopus 로고
    • Oral immunization of mice with ricin toxoid vaccine encapsulated in polymeric microspheres against aerosol challenge
    • Kende M,YanC,Hewetson J et al. (2002) Oral immunization of mice with ricin toxoid vaccine encapsulated in polymeric microspheres against aerosol challenge. Vaccine, 20, 1681-1691.
    • (2002) Vaccine , vol.20 , pp. 1681-1691
    • Kende, M.1    Yan, C.2    Hewetson, J.3
  • 80
    • 0027050799 scopus 로고
    • Analysis of several key active site residues of ricin A chain by mutagenesis and X-ray crystallography
    • Kim Y and Robertus JD (1992) Analysis of several key active site residues of ricin A chain by mutagenesis and X-ray crystallography. Protein Eng, 5, 775-779.
    • (1992) Protein Eng , vol.5 , pp. 775-779
    • Kim, Y.1    Robertus, J.D.2
  • 81
    • 2442708594 scopus 로고
    • Lehrbuch Der Intoxikationen, Second Edition
    • Stuttgart, Germany: Ferdinard Enke
    • Kobert R (1906). Lehrbuch Der Intoxikationen, Second Edition. Stuttgart, Germany: Ferdinard Enke.
    • (1906)
    • Kobert, R.1
  • 82
    • 0142112648 scopus 로고
    • Castor bean poisoning
    • Koch LA and Caplan J (1942) Castor bean poisoning. Am J Dis Child, 64, 485-486.
    • (1942) Am J Dis Child , vol.64 , pp. 485-486
    • Koch, L.A.1    Caplan, J.2
  • 83
    • 4243415294 scopus 로고
    • Acute pulmonary response of rats exposed to a sublethal dose of ricin aerosol
    • Kokes J, Assaad A, Pitt L et al. (1994) Acute pulmonary response of rats exposed to a sublethal dose of ricin aerosol. FASEB J, 8, A144.
    • (1994) FASEB J , vol.8
    • Kokes, J.1    Assaad, A.2    Pitt, L.3
  • 85
    • 0037357016 scopus 로고    scopus 로고
    • Oxidative stress associated hepatic and renal toxicity induced by ricin in mice
    • Kumar O, Sugendran K and Vijayaraghaven R (2003) Oxidative stress associated hepatic and renal toxicity induced by ricin in mice. Toxicon, 41, 333-338.
    • (2003) Toxicon , vol.41 , pp. 333-338
    • Kumar, O.1    Sugendran, K.2    Vijayaraghaven, R.3
  • 86
    • 0035265834 scopus 로고    scopus 로고
    • Interleukin-2 receptors and detergent-resistant membrane domains define a clathrin-independent endocytic pathway
    • Lamaze C, Dujeancourt A, Baba T et al. (2001) Interleukin-2 receptors and detergent-resistant membrane domains define a clathrin-independent endocytic pathway. Mol Cell, 7, 661-671.
    • (2001) Mol Cell , vol.7 , pp. 661-671
    • Lamaze, C.1    Dujeancourt, A.2    Baba, T.3
  • 87
    • 0022425912 scopus 로고
    • Nucleotide sequence of cloned cDNA coding for preproricin
    • Lamb FI, RobertsLMand Lord JM (1985) Nucleotide sequence of cloned cDNA coding for preproricin. Eur J Biochem, 148, 265-270.
    • (1985) Eur J Biochem , vol.148 , pp. 265-270
    • Lamb, F.I.1    Roberts, L.M.2    Lord, J.M.3
  • 88
    • 0032905566 scopus 로고    scopus 로고
    • Prediction of a conserved, neutralizing epitope in ribosomeinactivating proteins
    • Lebeda FJ and Olson MA (1999) Prediction of a conserved, neutralizing epitope in ribosomeinactivating proteins. Int J Biol Macromol, 24, 19-26.
    • (1999) Int J Biol Macromol , vol.24 , pp. 19-26
    • Lebeda, F.J.1    Olson, M.A.2
  • 89
    • 0142112646 scopus 로고
    • Pathological Changes Induced by Ricin Poisoning, PhD Thesis
    • Leeds, UK: University of Leeds
    • Leek MD (1989). Pathological Changes Induced by Ricin Poisoning, PhD Thesis. Leeds, UK: University of Leeds.
    • (1989)
    • Leek, M.D.1
  • 90
    • 0024788394 scopus 로고
    • Intestinal pathology following intramuscular ricin poisoning
    • Leek MD, Griffiths GD and Green MA (1989) Intestinal pathology following intramuscular ricin poisoning. J Pathol, 159, 329-324.
    • (1989) J Pathol , vol.159 , pp. 329-324
    • Leek, M.D.1    Griffiths, G.D.2    Green, M.A.3
  • 91
    • 0023759062 scopus 로고
    • Quantification of ricin toxin using a highly sensitive avidin/biotin enzyme-linked immunosorbent assay
    • Leith AG, Griffiths GD and Green MA (1988) Quantification of ricin toxin using a highly sensitive avidin/biotin enzyme-linked immunosorbent assay. J Forens Sci Soc, 28, 227-236.
    • (1988) J Forens Sci Soc , vol.28 , pp. 227-236
    • Leith, A.G.1    Griffiths, G.D.2    Green, M.A.3
  • 92
    • 0033868134 scopus 로고    scopus 로고
    • Rare Jatropha multifida intoxication in two children
    • Levin Y, Sherer Y, Bibi H et al. (2000) Rare Jatropha multifida intoxication in two children. J Emerg Med, 19, 173-175.
    • (2000) J Emerg Med , vol.19 , pp. 173-175
    • Levin, Y.1    Sherer, Y.2    Bibi, H.3
  • 93
    • 0023010495 scopus 로고
    • Ricin subunit association. Thermodynamics and the role of the disulfide bond in toxicity
    • Lewis MS and Youle RJ (1986) Ricin subunit association. Thermodynamics and the role of the disulfide bond in toxicity. J Biol Chem, 261, 11571-11577.
    • (1986) J Biol Chem , vol.261 , pp. 11571-11577
    • Lewis, M.S.1    Youle, R.J.2
  • 95
    • 0014965582 scopus 로고
    • Study on the effect of tryptic digestion on the toxicity of abrin
    • Lin J-Y, Kao C-L and Tung T-C (1970a) Study on the effect of tryptic digestion on the toxicity of abrin. J Formos Med Assoc, 69, 61-63.
    • (1970) J Formos Med Assoc , vol.69 , pp. 61-63
    • Lin, J.-Y.1    Kao, C.-L.2    Tung, T.-C.3
  • 96
    • 0014842155 scopus 로고
    • Distribution of I131-labeled abrin in vivo
    • Lin J-Y, Ju S-T, Shaw Y-S et al. (1970b) Distribution of I131-labeled abrin in vivo. Toxicon, 8, 197-201.
    • (1970) Toxicon , vol.8 , pp. 197-201
    • Lin, J.-Y.1    Ju, S.-T.2    Shaw, Y.-S.3
  • 97
    • 0019460964 scopus 로고
    • Isolation of four isotoxic proteins and one agglutinin from jequiriti bean (Abrus precatorius)
    • Lin J-Y, Lee T-C, Hu S-T et al. (1981) Isolation of four isotoxic proteins and one agglutinin from jequiriti bean (Abrus precatorius). Toxicon, 19, 41-51.
    • (1981) Toxicon , vol.19 , pp. 41-51
    • Lin, J.-Y.1    Lee, T.-C.2    Hu, S.-T.3
  • 98
    • 0032498544 scopus 로고    scopus 로고
    • Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus
    • Llorente A, Rapek A, Schmid SL et al. (1998) Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus. J Cell Biol, 140, 553-563.
    • (1998) J Cell Biol , vol.140 , pp. 553-563
    • Llorente, A.1    Rapek, A.2    Schmid, S.L.3
  • 99
    • 0014428030 scopus 로고
    • Anaphylaxis from an Indian necklace
    • Lockey SD Jr and Dunkelberger L (1968) Anaphylaxis from an Indian necklace. JAMA, 206, 2900-2901.
    • (1968) JAMA , vol.206 , pp. 2900-2901
    • Lockey Jr., S.D.1    Dunkelberger, L.2
  • 100
    • 0027398577 scopus 로고
    • Rab9 functions in transport between late endosomes and the trans Golgi network
    • Lombardi D, Soldati T, Riederer MA et al. (1993) Rab9 functions in transport between late endosomes and the trans Golgi network. EMBO J, 12, 677-682.
    • (1993) EMBO J , vol.12 , pp. 677-682
    • Lombardi, D.1    Soldati, T.2    Riederer, M.A.3
  • 101
    • 0021925967 scopus 로고
    • Precursors of ricin and Ricinus communis agglutinin. Glycosylation and processing during synthesis and intracellular transport
    • Lord JM (1985a) Precursors of ricin and Ricinus communis agglutinin. Glycosylation and processing during synthesis and intracellular transport. Eur J Biochem, 146, 411-416.
    • (1985) Eur J Biochem , vol.146 , pp. 411-416
    • Lord, J.M.1
  • 102
    • 0022425309 scopus 로고
    • Synthesis and intracellular transport of lectin and storage protein precursors in endosperm from castor bean
    • Lord JM (1985b) Synthesis and intracellular transport of lectin and storage protein precursors in endosperm from castor bean. Eur J Biochem, 146, 403-409.
    • (1985) Eur J Biochem , vol.146 , pp. 403-409
    • Lord, J.M.1
  • 103
    • 0028098025 scopus 로고
    • Ricin: structure, mode of action and some current applications
    • Lord JM, Roberts LM and Robertus JD (1994) Ricin: structure, mode of action and some current applications. FASEB J , 8, 201-208.
    • (1994) FASEB J , vol.8 , pp. 201-208
    • Lord, J.M.1    Roberts, L.M.2    Robertus, J.D.3
  • 105
    • 0027160323 scopus 로고
    • Characterization of two distinct pathways of endocytosis of ricin by rat liver endothelial cells
    • Magnusson S, Kjeken R and Berg T (1993) Characterization of two distinct pathways of endocytosis of ricin by rat liver endothelial cells. Exp Cell Res, 205, 118-125.
    • (1993) Exp Cell Res , vol.205 , pp. 118-125
    • Magnusson, S.1    Kjeken, R.2    Berg, T.3
  • 107
    • 0032538927 scopus 로고    scopus 로고
    • Direct pathway from early/recycling endosomes to the Golgi apparatus revealed through the study of shiga toxin B-fragment transport
    • Mallard F, Antony C, Tenza D et al. (1998) Direct pathway from early/recycling endosomes to the Golgi apparatus revealed through the study of shiga toxin B-fragment transport. J Cell Biol, 143, 973-990.
    • (1998) J Cell Biol , vol.143 , pp. 973-990
    • Mallard, F.1    Antony, C.2    Tenza, D.3
  • 108
    • 0033606772 scopus 로고    scopus 로고
    • Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathways
    • Mallet WG and Maxfield FR (1999) Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathways. J Cell Biol, 146, 345-359.
    • (1999) J Cell Biol , vol.146 , pp. 345-359
    • Mallet, W.G.1    Maxfield, F.R.2
  • 109
    • 3142647063 scopus 로고    scopus 로고
    • Insertional mutagenesis of ricin A chain: a novel route to an anti-ricin vaccine
    • Marsden CJ, Knight S, Smith DC et al. (2004) Insertional mutagenesis of ricin A chain: a novel route to an anti-ricin vaccine. Vaccine, 22, 2800-2805.
    • (2004) Vaccine , vol.22 , pp. 2800-2805
    • Marsden, C.J.1    Knight, S.2    Smith, D.C.3
  • 110
    • 17144400399 scopus 로고    scopus 로고
    • Ricin: current understanding and prospects for an antiricin vaccine
    • Marsden CJ, Smith DC, Roberts LM et al. (2005) Ricin: current understanding and prospects for an antiricin vaccine. Expert Rev Vaccines, 4, 229-237.
    • (2005) Expert Rev Vaccines , vol.4 , pp. 229-237
    • Marsden, C.J.1    Smith, D.C.2    Roberts, L.M.3
  • 111
    • 4143060688 scopus 로고    scopus 로고
    • Improved stability of a protein vaccine through elimination of a partially unfolded state
    • McHugh CA, Tammariello RF, Millard CB et al. (2004) Improved stability of a protein vaccine through elimination of a partially unfolded state. Protein Sci, 13, 2736-2743.
    • (2004) Protein Sci , vol.13 , pp. 2736-2743
    • McHugh, C.A.1    Tammariello, R.F.2    Millard, C.B.3
  • 112
    • 0142017308 scopus 로고
    • Poisoning by castor oil seeds
    • Meldrum WP (1900). Poisoning by castor oil seeds. Br Med J, 1, 317.
    • (1900) Br Med J , vol.1 , pp. 317
    • Meldrum, W.P.1
  • 113
    • 0034986208 scopus 로고    scopus 로고
    • IgE-mediated allergy to castor bean dust in a landscape gardener
    • Metz G, Böcher D and Metz J (2001) IgE-mediated allergy to castor bean dust in a landscape gardener. Contact Dermatitis, 44, 367.
    • (2001) Contact Dermatitis , vol.44 , pp. 367
    • Metz, G.1    Böcher, D.2    Metz, J.3
  • 114
    • 0027512828 scopus 로고
    • Structure of recombinant ricin A chain at 2.3 Å
    • Mlsna D, Monzingo AF, Katzin BJ et al. (1993) Structure of recombinant ricin A chain at 2.3 Å . Protein Sci, 2, 429-435.
    • (1993) Protein Sci , vol.2 , pp. 429-435
    • Mlsna, D.1    Monzingo, A.F.2    Katzin, B.J.3
  • 115
    • 0023654540 scopus 로고
    • The three dimensional structure of ricin at 2.8 Å
    • Montfort W, Villafranca JE, Monzingo AF et al. (1987) The three dimensional structure of ricin at 2.8 Å . J Biol Chem, 262, 5398-5403.
    • (1987) J Biol Chem , vol.262 , pp. 5398-5403
    • Montfort, W.1    Villafranca, J.E.2    Monzingo, A.F.3
  • 116
    • 0026469648 scopus 로고
    • X-ray analysis of substrate analogs in the ricin A-chain active site
    • Monzingo AF and Robertus JD (1992) X-ray analysis of substrate analogs in the ricin A-chain active site. J Mol Biol, 227, 1136-1145.
    • (1992) J Mol Biol , vol.227 , pp. 1136-1145
    • Monzingo, A.F.1    Robertus, J.D.2
  • 117
    • 0028179085 scopus 로고
    • Potential of polymer microencapsulation technology for vaccine innovation
    • Morris W, Steinhoff MC and Russell PK (1994) Potential of polymer microencapsulation technology for vaccine innovation. Vaccine, 12, 5-11.
    • (1994) Vaccine , vol.12 , pp. 5-11
    • Morris, W.1    Steinhoff, M.C.2    Russell, P.K.3
  • 118
    • 4243405179 scopus 로고
    • Zur Klinik und Pathogenese der Rizinvergiftung
    • Möschl H (1938) Zur Klinik und Pathogenese der Rizinvergiftung. Wien Klin Wochenschr, 51, 473-475.
    • (1938) Wien Klin Wochenschr , vol.51 , pp. 473-475
    • Möschl, H.1
  • 119
    • 0022005540 scopus 로고
    • Inhibition of coated pit formation in Hep2 cells blocks the cytotoxicity of diphtheria toxin but not that of ricin toxin
    • Moya M, Dautry-Varsat A, Goud B et al. (1985) Inhibition of coated pit formation in Hep2 cells blocks the cytotoxicity of diphtheria toxin but not that of ricin toxin. J Cell Biol, 101, 548-559.
    • (1985) J Cell Biol , vol.101 , pp. 548-559
    • Moya, M.1    Dautry-Varsat, A.2    Goud, B.3
  • 120
    • 1642494590 scopus 로고    scopus 로고
    • Ribosome-inactivating protein and apoptosis: abrin causes cell death via mitochondrial pathway in Jurkat cells
    • Narayanan S, Surolia A and Karande AA (2004) Ribosome-inactivating protein and apoptosis: abrin causes cell death via mitochondrial pathway in Jurkat cells. Biochem J , 377, 233-240.
    • (2004) Biochem J , vol.377 , pp. 233-240
    • Narayanan, S.1    Surolia, A.2    Karande, A.A.3
  • 122
    • 0022881369 scopus 로고
    • The mechanism of the protein-synthesis elongation cycle in eukaryotes. Effect of ricin on the ribosomal interaction with elongation factors
    • Nilsson L and NygårdO (1986) The mechanism of the protein-synthesis elongation cycle in eukaryotes. Effect of ricin on the ribosomal interaction with elongation factors. Eur J Biochem, 161, 111-117.
    • (1986) Eur J Biochem , vol.161 , pp. 111-117
    • Nilsson, L.1    Nygård, O.2
  • 123
    • 0014601125 scopus 로고
    • Toxicity studies with fractions from Abrus precatorius seed kernels
    • Niyogi SK and Rieders F (1969) Toxicity studies with fractions from Abrus precatorius seed kernels. Toxicon, 7, 211-216.
    • (1969) Toxicon , vol.7 , pp. 211-216
    • Niyogi, S.K.1    Rieders, F.2
  • 124
    • 1442348468 scopus 로고    scopus 로고
    • Plant-derived abrin-a induces apoptosis in cultured leukemic cell lines by different mechanisms
    • Ohba H, Moriwaki S, Bakalova R et al. (2004) Plant-derived abrin-a induces apoptosis in cultured leukemic cell lines by different mechanisms. Toxicol Appl Pharmacol, 195, 182-193.
    • (2004) Toxicol Appl Pharmacol , vol.195 , pp. 182-193
    • Ohba, H.1    Moriwaki, S.2    Bakalova, R.3
  • 125
    • 2442711021 scopus 로고
    • Abrin and ricin: structure and mechanism of action of two toxic lectins
    • Olsnes S (1976) Abrin and ricin: structure and mechanism of action of two toxic lectins. Bull InstPasteur, 74, 85-99.
    • (1976) Bull InstPasteur , vol.74 , pp. 85-99
    • Olsnes, S.1
  • 126
    • 0017795798 scopus 로고
    • Toxic and nontoxic lectins from Abrus precatorius
    • Olsnes S (1978) Toxic and nontoxic lectins from Abrus precatorius. Methods Enzymol, 50, 323-330.
    • (1978) Methods Enzymol , vol.50 , pp. 323-330
    • Olsnes, S.1
  • 127
    • 0002169483 scopus 로고
    • Toxic lectins and related proteins
    • P Cohen and S van Heyningen, eds, Amsterdam, The Netherlands: Elsevier
    • Olsnes S and Pihl A (1982). Toxic lectins and related proteins. In: Molecular Action of Toxins and Viruses (P Cohen and S van Heyningen, eds), pp. 51-105. Amsterdam, The Netherlands: Elsevier.
    • (1982) Molecular Action of Toxins and Viruses , pp. 51-105
    • Olsnes, S.1    Pihl, A.2
  • 129
    • 0033982982 scopus 로고    scopus 로고
    • Hepatotoxicity from castor bean ingestion in a child
    • PalatnickWand Tenenbein M (2000) Hepatotoxicity from castor bean ingestion in a child. J Toxicol Clin Toxicol, 38, 67-69.
    • (2000) J Toxicol Clin Toxicol , vol.38 , pp. 67-69
    • Palatnick, W.1    Tenenbein, M.2
  • 130
    • 1242342869 scopus 로고    scopus 로고
    • Infectious and toxic cellulitis due to suicide attempt by subcutaneous injection of ricin
    • Passeron T, Mantoux F, Lacour J-P et al. (2004) Infectious and toxic cellulitis due to suicide attempt by subcutaneous injection of ricin. Br J Dermatol, 150, 154.
    • (2004) Br J Dermatol , vol.150 , pp. 154
    • Passeron, T.1    Mantoux, F.2    Lacour, J.-P.3
  • 131
    • 0034924485 scopus 로고    scopus 로고
    • Ribosome-inactivating proteins from plants: more than RNA N-glycosidases?
    • Peumans WJ, Hao Q and van Damme EJM (2001) Ribosome-inactivating proteins from plants: more than RNA N-glycosidases? FASEB J, 15, 1493-1506.
    • (2001) FASEB J , vol.15 , pp. 1493-1506
    • Peumans, W.J.1    Hao, Q.2    Van Damme, E.J.M.3
  • 132
    • 0018627746 scopus 로고
    • Ricinusschrot-Allergie
    • Pevny I (1979) Ricinusschrot-Allergie. Dermatosen, 27, 159-162.
    • (1979) Dermatosen , vol.27 , pp. 159-162
    • Pevny, I.1
  • 134
    • 0030245817 scopus 로고    scopus 로고
    • Aerosolized specific antibody protects mice from lung injury associated with aerosolized ricin exposure
    • Poli MA, Rivera VR, Pitt ML et al. (1996) Aerosolized specific antibody protects mice from lung injury associated with aerosolized ricin exposure. Toxicon, 34, 1037-1044.
    • (1996) Toxicon , vol.34 , pp. 1037-1044
    • Poli, M.A.1    Rivera, V.R.2    Pitt, M.L.3
  • 135
    • 4444292852 scopus 로고    scopus 로고
    • Abrin induces HeLa cell apoptosis by cytochrome c release and caspase activation
    • Qu X and Qing L (2004) Abrin induces HeLa cell apoptosis by cytochrome c release and caspase activation. J Biochem Mol Biol, 37, 445-453.
    • (2004) J Biochem Mol Biol , vol.37 , pp. 445-453
    • Qu, X.1    Qing, L.2
  • 136
    • 0024592576 scopus 로고
    • The toxicity, distribution and excretion of ricin holotoxin in rats
    • Ramsden CS, Drayson MT and Bell EB (1989) The toxicity, distribution and excretion of ricin holotoxin in rats. Toxicology, 55, 161-171.
    • (1989) Toxicology , vol.55 , pp. 161-171
    • Ramsden, C.S.1    Drayson, M.T.2    Bell, E.B.3
  • 137
    • 0030929658 scopus 로고    scopus 로고
    • Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol
    • Rapak A, Falnes PØ and Olsnes S (1997) Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol. Proc Natl Acad Sci USA, 94, 3783-3788.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3783-3788
    • Rapak, A.1    Falnes, Pø.2    Olsnes, S.3
  • 138
    • 0022321305 scopus 로고
    • Castor bean toxicity reexamined: a new perspective
    • Rauber A and Heard J (1985) Castor bean toxicity reexamined: a new perspective. Vet Human Toxicol, 27, 498-502.
    • (1985) Vet Human Toxicol , vol.27 , pp. 498-502
    • Rauber, A.1    Heard, J.2
  • 139
    • 0019459028 scopus 로고
    • Internalization of ricin in Chinese hamster ovary cells
    • Ray B and Wu HC (1981) Internalization of ricin in Chinese hamster ovary cells. Mol Cell Biol, 1, 544-551.
    • (1981) Mol Cell Biol , vol.1 , pp. 544-551
    • Ray, B.1    Wu, H.C.2
  • 140
    • 0025986909 scopus 로고
    • Sitedirected mutagenesis of ricin A-chain and implications for the mechanism of action
    • Ready MP, Kim Y and Robertus JD (1991) Sitedirected mutagenesis of ricin A-chain and implications for the mechanism of action. Proteins, 10, 270-278.
    • (1991) Proteins , vol.10 , pp. 270-278
    • Ready, M.P.1    Kim, Y.2    Robertus, J.D.3
  • 141
    • 0024463661 scopus 로고
    • Recombinant proricin binds galactose but does not depurinate 28 S ribosomal RNA
    • Richardson PT, Westby M, Roberts LM et al. (1989) Recombinant proricin binds galactose but does not depurinate 28 S ribosomal RNA. FEBS Lett, 255, 15-20.
    • (1989) FEBS Lett , vol.255 , pp. 15-20
    • Richardson, P.T.1    Westby, M.2    Roberts, L.M.3
  • 142
    • 0028224561 scopus 로고
    • Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network
    • Riederer MA, Soldati T, Shapiro AD et al. (1994) Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network. J Cell Biol, 125, 573-582.
    • (1994) J Cell Biol , vol.125 , pp. 573-582
    • Riederer, M.A.1    Soldati, T.2    Shapiro, A.D.3
  • 143
    • 0019855611 scopus 로고
    • The synthesis of Ricinus communis agglutinin, cotranslational and posttranslational modification of agglutinin polypeptides
    • Roberts LM and Lord JM (1981) The synthesis of Ricinus communis agglutinin, cotranslational and posttranslational modification of agglutinin polypeptides. Eur J Biochem, 119, 31-41.
    • (1981) Eur J Biochem , vol.119 , pp. 31-41
    • Roberts, L.M.1    Lord, J.M.2
  • 145
    • 0032931988 scopus 로고    scopus 로고
    • Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles
    • Rodal SK, Skretting G, Garred O et al. (1999) Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles. Mol Biol Cell, 10, 961-974.
    • (1999) Mol Biol Cell , vol.10 , pp. 961-974
    • Rodal, S.K.1    Skretting, G.2    Garred, O.3
  • 146
    • 0015039470 scopus 로고
    • Some actions of the seeds of Abrus precatorius
    • Routh BC and Lahiri SC (1971) Some actions of the seeds of Abrus precatorius. Bull Calcutta Sch Trop Med, 19, 46-47.
    • (1971) Bull Calcutta Sch Trop Med , vol.19 , pp. 46-47
    • Routh, B.C.1    Lahiri, S.C.2
  • 147
    • 0025939115 scopus 로고
    • Structure of ricin B-chain at 2.5 ̊A resolution (1991)
    • Rutenber E and Robertus JD (1991) Structure of ricin B-chain at 2.5 ̊A resolution (1991). Proteins, 10, 260-269.
    • (1991) Proteins , vol.10 , pp. 260-269
    • Rutenber, E.1    Robertus, J.D.2
  • 148
    • 0025996872 scopus 로고
    • Crystallographic refinement of ricin to 2.5 Å
    • Rutenber E, Katzin BJ, Ernst S et al. (1991) Crystallographic refinement of ricin to 2.5 Å . Proteins, 10, 240-250.
    • (1991) Proteins , vol.10 , pp. 240-250
    • Rutenber, E.1    Katzin, B.J.2    Ernst, S.3
  • 149
    • 0029909329 scopus 로고    scopus 로고
    • Endocytosis, intracellular transport and cytotoxic action of Shiga toxin and ricin
    • Sandvig K and van Deurs B (1996) Endocytosis, intracellular transport and cytotoxic action of Shiga toxin and ricin. Physiol Rev, 76, 949-966.
    • (1996) Physiol Rev , vol.76 , pp. 949-966
    • Sandvig, K.1    Van Deurs, B.2
  • 150
    • 0034669117 scopus 로고    scopus 로고
    • Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives
    • Sandvig K and van Deurs B (2000) Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives. EMBO J, 19, 5943-5950.
    • (2000) EMBO J , vol.19 , pp. 5943-5950
    • Sandvig, K.1    Van Deurs, B.2
  • 151
    • 0036185430 scopus 로고    scopus 로고
    • Pathways followed by ricin and Shiga toxin into cells
    • Sandvig K, Grimmer S, Lauvrak SU et al. (2002) Pathways followed by ricin and Shiga toxin into cells. Histochem Cell Biol, 117, 131-141.
    • (2002) Histochem Cell Biol , vol.117 , pp. 131-141
    • Sandvig, K.1    Grimmer, S.2    Lauvrak, S.U.3
  • 152
    • 0035126881 scopus 로고    scopus 로고
    • The toxicity of deglycosylated ricin A-chaincontaining immunotoxins in patients with non-Hodgkin's lymphoma is exacerbated by prior radiotherapy: a retrospective analysis of patients in five clinical trials
    • Schindler J, Sausville E, Messmann R et al. (2001) The toxicity of deglycosylated ricin A-chaincontaining immunotoxins in patients with non-Hodgkin's lymphoma is exacerbated by prior radiotherapy: a retrospective analysis of patients in five clinical trials. Clin Cancer Res, 7, 255-258.
    • (2001) Clin Cancer Res , vol.7 , pp. 255-258
    • Schindler, J.1    Sausville, E.2    Messmann, R.3
  • 153
    • 0024756611 scopus 로고
    • Role of glutamic acid 177 of the ricin toxin A chain in enzymatic inactivation of ribosomes
    • Schlossman D,Withers D,Welsh P et al. (1989) Role of glutamic acid 177 of the ricin toxin A chain in enzymatic inactivation of ribosomes. Mol Cell Biol, 9, 5012-5021.
    • (1989) Mol Cell Biol , vol.9 , pp. 5012-5021
    • Schlossman, D.1    Withers, D.2    Welsh, P.3
  • 154
    • 0035877840 scopus 로고    scopus 로고
    • Abrin triggers cell death by inactivating a thiol-specific antioxidant
    • Shih S-F, Wu Y-H, Hung C-H et al. (2001) Abrin triggers cell death by inactivating a thiol-specific antioxidant. J Biol Chem, 276, 21870-21877.
    • (2001) J Biol Chem , vol.276 , pp. 21870-21877
    • Shih, S.-F.1    Wu, Y.-H.2    Hung, C.-H.3
  • 155
    • 0036075580 scopus 로고    scopus 로고
    • Monoclonal antibody-based enzyme immunoassay for detection of ricin
    • Shyu H-F, Chiao D-J, Liu H-W et al. (2002a) Monoclonal antibody-based enzyme immunoassay for detection of ricin. Hybrid Hybridomics, 21, 69-73.
    • (2002) Hybrid Hybridomics , vol.21 , pp. 69-73
    • Shyu, H.-F.1    Chiao, D.-J.2    Liu, H.-W.3
  • 156
    • 0034756339 scopus 로고    scopus 로고
    • Colloidal gold-based immunochromatographic assay for detection of ricin
    • Shyu R-H, Shyu H-F, Liu H-W et al. (2002b) Colloidal gold-based immunochromatographic assay for detection of ricin. Toxicon, 40, 255-258.
    • (2002) Toxicon , vol.40 , pp. 255-258
    • Shyu, R.-H.1    Shyu, H.-F.2    Liu, H.-W.3
  • 157
    • 0022982241 scopus 로고
    • Mannose receptor-mediated uptake of ricin toxin and ricin A chain by macrophages. Multiple intracellular pathways for a chain translocation
    • Simmons BM, Stahl PD and Russell JH (1986) Mannose receptor-mediated uptake of ricin toxin and ricin A chain by macrophages. Multiple intracellular pathways for a chain translocation. J Biol Chem, 261, 7912-7920.
    • (1986) J Biol Chem , vol.261 , pp. 7912-7920
    • Simmons, B.M.1    Stahl, P.D.2    Russell, J.H.3
  • 158
    • 0031868419 scopus 로고    scopus 로고
    • Expression of mutant dynamin protects cells against diphtheria toxin but not against ricin
    • Simpson JC, Smith DC, Roberts LM et al. (1998) Expression of mutant dynamin protects cells against diphtheria toxin but not against ricin. Exp Cell Res, 239, 293-300.
    • (1998) Exp Cell Res , vol.239 , pp. 293-300
    • Simpson, J.C.1    Smith, D.C.2    Roberts, L.M.3
  • 159
    • 0037056037 scopus 로고    scopus 로고
    • A novel recombinant vaccine which protects mice against ricin intoxication
    • Smallshaw JE, Firan A, Fulmer JR et al. (2002) A novel recombinant vaccine which protects mice against ricin intoxication. Vaccine, 20, 3422-3427.
    • (2002) Vaccine , vol.20 , pp. 3422-3427
    • Smallshaw, J.E.1    Firan, A.2    Fulmer, J.R.3
  • 160
    • 0037382907 scopus 로고    scopus 로고
    • Genetic engineering of an immunotoxin to eliminate pulmonary vascular leak in mice
    • Smallshaw JE, Ghetie V, Rizo J et al. (2003) Genetic engineering of an immunotoxin to eliminate pulmonary vascular leak in mice. Nat Biotechnol, 21, 387-391.
    • (2003) Nat Biotechnol , vol.21 , pp. 387-391
    • Smallshaw, J.E.1    Ghetie, V.2    Rizo, J.3
  • 161
    • 0036644191 scopus 로고    scopus 로고
    • Exogenous peptides delivered by ricin require processing by signal peptidase for transporter associated with antigen processing-independent MHC class1-restricted presentation
    • Smith DC, Gallimore A, Jones E et al. (2002) Exogenous peptides delivered by ricin require processing by signal peptidase for transporter associated with antigen processing-independent MHC class1-restricted presentation. J Immunol, 169, 99-107.
    • (2002) J Immunol , vol.169 , pp. 99-107
    • Smith, D.C.1    Gallimore, A.2    Jones, E.3
  • 162
    • 0027219786 scopus 로고
    • Ricin A-chain and ricin A-chain immunotoxins rapidly damage human endothelial cells: implications for vascular leak syndrome
    • Soler-Rodriguez A-M, Ghetie M-A, Oppenheimer-Marks N et al. (1993) Ricin A-chain and ricin A-chain immunotoxins rapidly damage human endothelial cells: implications for vascular leak syndrome. Exp Cell Res, 206, 227-234.
    • (1993) Exp Cell Res , vol.206 , pp. 227-234
    • Soler-Rodriguez, A.-M.1    Ghetie, M.-A.2    Oppenheimer-Marks, N.3
  • 163
    • 0015801981 scopus 로고
    • Inhibition by ricin of protein synthesis in vitro: 60S ribosomal subunit as the target of the toxin
    • Sperti S, Montanaro L, Mattioli A et al. (1973) Inhibition by ricin of protein synthesis in vitro: 60S ribosomal subunit as the target of the toxin. Biochem J, 136, 813-815.
    • (1973) Biochem J , vol.136 , pp. 813-815
    • Sperti, S.1    Montanaro, L.2    Mattioli, A.3
  • 164
    • 0042311010 scopus 로고    scopus 로고
    • Role of lipids in the retrograde pathway of ricin intoxication
    • Spilsberg B, Van Meer G and Sandvig K (2003) Role of lipids in the retrograde pathway of ricin intoxication. Traffic, 4, 544-552.
    • (2003) Traffic , vol.4 , pp. 544-552
    • Spilsberg, B.1    Van Meer, G.2    Sandvig, K.3
  • 165
    • 0020359460 scopus 로고
    • A castor bean poisoning and a widely available bioassay for ricin
    • Spyker DA, Sauer K, Kell SO et al. (1982) A castor bean poisoning and a widely available bioassay for ricin. Vet Human Toxicol, 24, 293.
    • (1982) Vet Human Toxicol , vol.24 , pp. 293
    • Spyker, D.A.1    Sauer, K.2    Kell, S.O.3
  • 166
    • 14744291476 scopus 로고
    • Ribosome-inactivating proteins from plants: present status and future prospects
    • Stirpe F, Barbieri L, Battelli MG et al. (1992) Ribosome-inactivating proteins from plants: present status and future prospects. Biotechnology, 10, 405-412.
    • (1992) Biotechnology , vol.10 , pp. 405-412
    • Stirpe, F.1    Barbieri, L.2    Battelli, M.G.3
  • 167
    • 2442663617 scopus 로고
    • Failure of whole bowel irrigation to decontaminate the GI tract following massive jequirity bean ingestion
    • Swanson-Biearman B, Dean BS and Krenzelok EP (1992) Failure of whole bowel irrigation to decontaminate the GI tract following massive jequirity bean ingestion. Vet Human Toxicol, 34, 352.
    • (1992) Vet Human Toxicol , vol.34 , pp. 352
    • Swanson-Biearman, B.1    Dean, B.S.2    Krenzelok, E.P.3
  • 168
    • 0142017306 scopus 로고    scopus 로고
    • Suicidal poisoning with castor bean (Ricinus communis) extract injected subcutaneously-case report
    • Targosz D, Winnik L and Szkolnicka B (2002) Suicidal poisoning with castor bean (Ricinus communis) extract injected subcutaneously-case report. J Toxicol Clin Toxicol, 40, 398.
    • (2002) J Toxicol Clin Toxicol , vol.40 , pp. 398
    • Targosz, D.1    Winnik, L.2    Szkolnicka, B.3
  • 169
    • 0028446541 scopus 로고
    • Correlation between the activities of five ribosomeinactivating proteins in depurination of tobacco ribosomes and inhibition of tobacco mosaic virus infection
    • Taylor S, Massiah A, Lomonossoff G et al. (1994) Correlation between the activities of five ribosomeinactivating proteins in depurination of tobacco ribosomes and inhibition of tobacco mosaic virus infection. Plant J, 5, 827-835.
    • (1994) Plant J , vol.5 , pp. 827-835
    • Taylor, S.1    Massiah, A.2    Lomonossoff, G.3
  • 170
    • 0020400620 scopus 로고
    • Castor bean allergy among workers in the felt industry
    • Topping MD, Henderson RTS, Luczynska CM et al. (1982) Castor bean allergy among workers in the felt industry. Allergy, 37, 603-608.
    • (1982) Allergy , vol.37 , pp. 603-608
    • Topping, M.D.1    Henderson, R.T.S.2    Luczynska, C.M.3
  • 171
    • 0027203046 scopus 로고
    • Mutations in human dynamin block-an intermediate stage in coated vesicle formation
    • Van der Bliek AM, Redelmeier TE, Damke H et al. (1993) Mutations in human dynamin block-an intermediate stage in coated vesicle formation. J Cell Biol, 122, 553-563.
    • (1993) J Cell Biol , vol.122 , pp. 553-563
    • Van der Bliek, A.M.1    Redelmeier, T.E.2    Damke, H.3
  • 172
    • 0021965748 scopus 로고
    • Receptor-mediated endocytosis of a ricin-colloidal gold conjugate in vero cells. Intracellular routing of vacuolar and tubulo-vesicular portions of the endosomal system
    • van Deurs B, Pedersen LR, Sundan A et al. (1985) Receptor-mediated endocytosis of a ricin-colloidal gold conjugate in vero cells. Intracellular routing of vacuolar and tubulo-vesicular portions of the endosomal system. Exp Cell Res, 159, 287-304.
    • (1985) Exp Cell Res , vol.159 , pp. 287-304
    • van Deurs, B.1    Pedersen, L.R.2    Sundan, A.3
  • 173
    • 0023878452 scopus 로고
    • Estimation of the amount of internalized ricin that reaches the trans-Golgi network
    • van Deurs B, Sandvig K, Petersen OW et al. (1988) Estimation of the amount of internalized ricin that reaches the trans-Golgi network. J Cell Biol, 106, 253-267.
    • (1988) J Cell Biol , vol.106 , pp. 253-267
    • van Deurs, B.1    Sandvig, K.2    Petersen, O.W.3
  • 174
    • 0019432633 scopus 로고
    • Ricin B chain is a product of gene duplication
    • Villafranca JE and Robertus JD (1981) Ricin B chain is a product of gene duplication. J Biol Chem, 256, 554-556.
    • (1981) J Biol Chem , vol.256 , pp. 554-556
    • Villafranca, J.E.1    Robertus, J.D.2
  • 176
    • 0034698028 scopus 로고    scopus 로고
    • Essential role of dynamin in internalization of M2 muscarinic acetylcholine and angiotensin AT1A receptors
    • Werbonat Y, Kleutges N, Jakobs KH et al. (2000) Essential role of dynamin in internalization of M2 muscarinic acetylcholine and angiotensin AT1A receptors. J Biol Chem, 275, 21969-21974.
    • (2000) J Biol Chem , vol.275 , pp. 21969-21974
    • Werbonat, Y.1    Kleutges, N.2    Jakobs, K.H.3
  • 177
    • 0028099436 scopus 로고
    • X-ray structure of recombinant ricin A-chain at 1.8 ̊A resolution
    • Weston SA, Tucker AD, Thatcher DR et al. (1994) X-ray structure of recombinant ricin A-chain at 1.8 ̊A resolution. J Mol Biol, 244, 410-422.
    • (1994) J Mol Biol , vol.244 , pp. 410-422
    • Weston, S.A.1    Tucker, A.D.2    Thatcher, D.R.3
  • 178
    • 0033571602 scopus 로고    scopus 로고
    • Rab6 coordinates a novel Golgi to ER retrograde transport pathway in live cells
    • White J, Johannes L, Mallard F et al. (1999) Rab6 coordinates a novel Golgi to ER retrograde transport pathway in live cells. J Cell Biol, 147, 743-760.
    • (1999) J Cell Biol , vol.147 , pp. 743-760
    • White, J.1    Johannes, L.2    Mallard, F.3
  • 179
    • 0001695604 scopus 로고
    • Lesions of acute inhaled lethal ricin intoxication in rhesus monkeys
    • Wilhelmsen C and Pitt L (1993) Lesions of acute inhaled lethal ricin intoxication in rhesus monkeys. Vet Pathol, 30, 482.
    • (1993) Vet Pathol , vol.30 , pp. 482
    • Wilhelmsen, C.1    Pitt, L.2
  • 180
    • 0002826533 scopus 로고    scopus 로고
    • Structure and function of the sarcin-rich domain
    • J Garrett, L Douthwaite, PJ Lilias et al., eds, Washington, DC, USA: American Society for Microbiology
    • Wool IG, Correll CC and Yuen-Ling C (2000). Structure and function of the sarcin-rich domain. In: The Ribosome: Structure, Function, Antibiotics and Cellular Interactions (J Garrett, L Douthwaite, PJ Lilias et al., eds), pp. 461-473. Washington, DC, USA: American Society for Microbiology.
    • (2000) The Ribosome: Structure, Function, Antibiotics and Cellular Interactions , pp. 461-473
    • Wool, I.G.1    Correll, C.C.2    Yuen-Ling, C.3
  • 181
    • 0023375119 scopus 로고
    • The intersubunit disulfide bridge of ricin is essential for cytotoxicity
    • Wright HT and Robertus JD (1987) The intersubunit disulfide bridge of ricin is essential for cytotoxicity. Arch Biochem Biophys, 256, 280-284.
    • (1987) Arch Biochem Biophys , vol.256 , pp. 280-284
    • Wright, H.T.1    Robertus, J.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.