High prevalence of major cardiovascular risk factors in first-degree relatives of individuals with familial premature coronary artery disease-The GENECARD project

Atherosclerosis

Volumn 194, Issue 1, 2007, Pages 253-264

  Hurrell, Claire ^a   Wietlisbach, Vincent ^b   Jotterand, Valerie ^a   Volet, Marianne ^a   Lenain, Vincent ^a   Nicod, Pascal ^a   Darioli, Roger ^a   Paccaud, Fred ^b   Waeber, Gerard ^a   Mooser, Vincent ^c  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c GLAXOSMITHKLINE   (United States)

Author keywords

Coronary artery disease; Epidemiology; Family; Genetics; Population controls; Risk factors

Indexed keywords

ABDOMINAL OBESITY; ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FAMILIAL PREMATURE CORONARY ARTERY DISEASE; FAMILY; FEMALE; GENETIC SUSCEPTIBILITY; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; METABOLIC DISORDER; METHODOLOGY; POPULATION DYNAMICS; PREVALENCE; PRIORITY JOURNAL; PROGENY; RELATIVE; RISK FACTOR; SIBLING; SMOKING; SPOUSE;

ABDOMINAL FAT; ADULT; ADULT CHILDREN; AGE OF ONSET; BODY MASS INDEX; CORONARY ARTERY DISEASE; FAMILY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERCHOLESTEROLEMIA; HYPERTENSION; MALE; MIDDLE AGED; OBESITY; PREVALENCE; RISK FACTORS; SIBLINGS; SMOKING; SPOUSES;

EID: 34648843012     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2006.08.004     Document Type: Article

References (16)

1. Williams R.R., Hunt S.C., Heiss G., et al. Usefulness of cardiovascular family history data for population-based preventive medicine and medical research (the Health Family Tree Study and the NHLBI Family Heart Study). Am J Cardiol 87 (2001) 129-135
2. Sesso H.D., Lee I.M., Gaziano J.M., et al. Maternal and paternal history of myocardial infarction and risk of cardiovascular disease in men and women. Circulation 104 (2001) 393-398
3. Schildkraut J.M., Myers R.H., Cupples L.A., Kiely D.K., and Kannel W.B. Coronary risk associated with age and sex of parental heart disease in the Framingham Study. Am J Cardiol 64 (1989) 555-559
4. Jousilahti P., Puska P., Vartiainen E., Pekkanen J., and Tuomilehto J. Parental history of premature coronary heart disease: an independent risk factor of myocardial infarction. J Clin Epidemiol 49 (1996) 497-503
5. Marenberg M.E., Risch N., Berkman L.F., Floderus B., and de Faire U. Genetic susceptibility to death from coronary heart disease in a study of twins. N Engl J Med 330 (1994) 1041-1046
6. Goldstein J.L., Schrott H.G., Hazzard W.R., Bierman E.L., and Motulsky A.G. Hyperlipidemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidemia. J Clin Invest 52 (1973) 1544-1568
7. Wang L., Fan C., Topol S.E., Topol E.J., and Wang Q. Mutation of MEF2A in an inherited disorder with features of coronary artery disease. Science 302 (2003) 1578-1581
8. Hauser E.R., Mooser V., Crossman D.C., et al. Design of the Genetics of Early Onset Cardiovascular Disease (GENECARD) study. Am Heart J 145 (2003) 602-613
9. Jomini V., Oppliger-Pasquali S., Wietlisbach V., et al. Contribution of major cardiovascular risk factors to familial premature coronary artery disease: the GENECARD project. J Am Coll Cardiol 40 (2002) 676-684
10. Anwar Y.A., Giacco S., McCabe E.J., Tendler B.E., and White W.B. Evaluation of the efficacy of the Omron HEM-737 IntelliSense device for use on adults according to the recommendations of the Association for the Advancement of Medical Instrumentation. Blood Press Monit 3 (1998) 261-265
11. Wietlisbach V., Paccaud F., Rickenbach M., and Gutzwiller F. Trends in cardiovascular risk factors (1984-1993) in a Swiss region: results of three population surveys. Prev Med 26 (1997) 523-533
12. Tunstall-Pedoe H., Kuulasmaa K., Mahonen M., et al. Contribution of trends in survival and coronary-event rates to changes in coronary heart disease mortality: 10-year results from 37 WHO MONICA project populations. Monitoring trends and determinants in cardiovascular disease. Lancet 353 (1999) 1547-1557
13. Hosmer D.W.L.S. Applied logistic regression (1989), John Wiley & Sons, New York, NY
14. Hauser E.R., Crossman D.C., Granger C.B., et al. A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study. Am J Hum Genet 75 (2004) 436-447
15. Hengstenberg C., Holmer S.R., Mayer B., et al. Siblings of myocardial infarction patients are overlooked in primary prevention of cardiovascular disease. Eur Heart J 22 (2001) 926-933
16. McGill Jr. H.C., McMahan C.A., Zieske A.W., et al. Effects of nonlipid risk factors on atherosclerosis in youth with a favorable lipoprotein profile. Circulation 103 (2001) 1546-1550