The effects of memory, attention, and executive dysfunction on outcomes of depression in a primary care intervention trial: The PROSPECT study

International Journal of Geriatric Psychiatry

Volumn 22, Issue 9, 2007, Pages 922-929

  Bogner, Hillary R ^a   Bruce, Martha L ^b   Reynolds III, Charles F ^c   Mulsant, Benoit H ^c,d   Cary, Mark S ^a   Morales, Knashawn ^a   Alexopoulos, George S ^b   Schulberg, Herbert C ^e   Katz, Ira ^a   Have, Thomas Ten ^a   Brown, Gregory K ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

^e University of Pennsylvania ^*  (United States)

Author keywords

Aged; Cognition; Depression; Primary health care; Treatment

Indexed keywords

ANTIDEPRESSANT AGENT;

ADULT; AGED; ALGORITHM; ARTICLE; ATTENTION; CLINICAL TRIAL; COGNITION; COGNITIVE DEFECT; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DATA ANALYSIS; DEPRESSION; DISEASE SEVERITY; ELDERLY CARE; FEMALE; HAMILTON SCALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MANAGER; MEMORY; MINI MENTAL STATE EXAMINATION; OUTCOME ASSESSMENT; PRIMARY MEDICAL CARE; RANDOMIZED CONTROLLED TRIAL; REMISSION; RISK ASSESSMENT; TREATMENT RESPONSE; VERBAL MEMORY; WECHSLER INTELLIGENCE SCALE;

AGED; AGED, 80 AND OVER; ATTENTION; COGNITION DISORDERS; DEPRESSION; FEMALE; HUMANS; MALE; MEMORY; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; ODDS RATIO; PATIENT CARE MANAGEMENT; PRIMARY HEALTH CARE; PSYCHIATRIC STATUS RATING SCALES; PSYCHOTHERAPY; REMISSION INDUCTION; TIME FACTORS; TREATMENT OUTCOME;

EID: 34648820028     PISSN: 08856230     EISSN: 10991166     Source Type: Journal    
DOI: 10.1002/gps.1767     Document Type: Article

References (26)

1. Alexopoulos GS, Katz IR, Bruce ML, et al. 2005a. Remission in depressed geriatric primary care patients: a report from the PROSPECT study. Am J Psychiatry 162: 718-724.
2. Alexopoulos GS, Kiosses DN, Heo M, et al. 2005b. Executive dysfunction and the course of geriatric depression. Biol Psychiatry 58: 204-210.
3. Alexopoulos GS, Kiosses DN, Klimstra S, et al. 2002. Clinical presentation of the 'depression-executive dysfunction syndrome' of late life. Am J Geriatr Psychiatry 10: 98-106.
4. Alexopoulos GS, Kiosses DN, Murphy C, Heo M. 2004. Executive dysfunction, heart disease burden, and remission of geriatric depression. Neuropsychopharmacol 29: 2278-2284.
5. Alexopoulos GS, Meyers BS, Young RC, et al. 1997. 'Vascular depression' hypothesis. Arch Gen Psychiatry 54: 915-922.
6. Alexopoulos GS, Meyers BS, Young RC, et al. 2000. Executive dysfunction and long-term outcomes of geriatric depression. Arch Gen Psychiatry 57: 285-290.
7. Alexopoulos GS, Raue P, Arean P. 2003. Problem-solving therapy versus supportive therapy in geriatric major depression with executive dysfunction. Am J Geriatr Psychiatry 11: 46-52.
8. Bogner HR, Cary M, Bruce ML, et al. 2005. The role of medical comorbidity in outcome of major depression in primary care: the PROSPECT study. Am J Geriatr Psychiatry 13: 861-868.
9. Bruce ML, Ten Have TR, Reynolds CF III, et al. 2004. A randomized controlled trial to reduce suicidal ideation and depressive symptoms in depressed older primary care patients: the PROSPECT study. JAMA 291: 1081-1091.
10. Butters MA, Bhalla RK, Mulsant BH, et al. 2004. Executive functioning, illness course, and relapse/recurrence in continuation and maintenance treatment of late-life depression. Is there a relationship? Am J Geriatr Psychiatry 12: 387-394.
11. Crum RM, Anthony JC, Bassett SS, Folstein MF. 1993. Population-based norms for the Mini-Mental State Examination by age and educational level. JAMA 269: 2386-2391.
12. Dunkin JJ, Leuchter AF, Cook IA, et al. 2000. Executive dysfunction predicts nonresponse to fluoxetine in major depression. J Affect Disord. 60: 13-23.
13. Folstein MF, Folstein SE, McHugh PR. 1975. 'Mini-Mental State': a practical method for grading the cognitive state of patients for the clinician. J Psychiatric Res 12: 189-198.
14. Golden CJ. 1978. The Stroop Color and Word Test (Manual). Stoetling: Chicago, IL.
15. Hamilton M. 1960. A rating scale for depression. J Neurology Neurosurgic Psychiatry 23: 56-62.
16. Kalayam B, Alexopoulos GS. 1999. Prefrontal dysfunction and treatment response in geriatric depression. Arch Gen Psychiatry 56: 713-718.
17. Lecrubier Y. 2002. How do you define remission? Acta Psychiatrica Scand Suppl 415: 7-11.
18. Mattis S. 1988. Dementia Rating Scale. Psychological Assessment Resources: Odessa, FL.
19. Mulsant BH, Alexopoulos GS, Reynolds CF III, et al. 2001. Pharmacological treatment of depression in older primary care patients: the PROSPECT algorithm. Int J Geriatr Psychiatry 16: 585-592.
20. Potter GG, Kittinger JD, Wagner HR, et al. 2004. Prefrontal neuropsychological predictors of treatment remission in late-life depression. Neuropsychopharmacol 29: 2266-2271.
21. Schulberg HC, Bryce C, Chism K, et al. 2001. Managing late-life depression in primary care practice: a case study of the Health Specialist's role. Int J Geriatr Psychiatry 16: 577-584.
22. Spitzer RL, Gibbon M, Williams JB. 1995. Structured Clinical Interview for Axis I DSM-IV Disorders (SCID). American Association Press, Inc.: Washington, DC.
23. Steffens DC, Snowden M, Fan MY, et al. 2006. Cognitive impairment and depression outcomes in the IMPACT study. Am J Geriatr Psychiatry 14: 401-409.
24. Tombaugh TN, McIntyre NJ. 1992. The Mini-Mental State Examination: a comprehensive review. J Am Geriatr Soc 40: 922-935.
25. Wechler D. 1981. Wechsler Adult Intelligence Scale, revised. Psychological Corporation: New York.
26. Wells KB, Sherbourne C, Schoenbaum M, et al. 2000. Impact of disseminating quality improvement programs for depression in managed primary care: a randomized controlled trial. JAMA 283: 212-220.