Executive dysfunction, heart disease burden, and remission of geriatric depression

Neuropsychopharmacology

Volumn 29, Issue 12, 2004, Pages 2278-2284

  Alexopoulos, George S ^a   Kiosses, Dimitris N ^a   Murphy, Christopher ^a   Heo, Moonseong ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Depression; Elderly; Executive impairment; Heart disease burden; Remission

Indexed keywords

CITALOPRAM;

ADULT; AGED; ARTICLE; BODY BURDEN; BRAIN DYSFUNCTION; COGNITIVE DEFECT; CONTROLLED STUDY; DEMENTIA; DEPRESSION; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISABILITY; FEMALE; GERONTOPSYCHIATRY; HEART DISEASE; HUMAN; MAJOR CLINICAL STUDY; MALE; PERSEVERATION; PRIORITY JOURNAL; PSYCHIATRIC TREATMENT; PSYCHOLOGIC TEST; RATING SCALE; REMISSION; SCHIZOPHRENIA; TREATMENT OUTCOME;

AGED; ANTIDEPRESSIVE AGENTS; CITALOPRAM; COGNITION DISORDERS; COST OF ILLNESS; DEPRESSIVE DISORDER, MAJOR; FEMALE; GERIATRIC ASSESSMENT; HEART DISEASES; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PROBLEM SOLVING; PSYCHIATRIC STATUS RATING SCALES; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 9644266684     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300557     Document Type: Article

References (55)

1. Aizenstein HJ, Nebes RD, Meltzer CC, Fukui MB, Williams RL, Saxton J et al (2002). The relation of white matter hyperintensities to implicit learning in healthy older adults. Int J Geriatr Psychiatry 17: 664-669.
2. Alexopoulos GS (2002). Frontostriatal and limbic dysfunction in late-life depression. Am J Geriatr Psychiatry 10: 687-695.
3. Alexopoulos GS, Kiosses DN, Choi SJ, Murphy CF, Lim KO (2002a). Frontal white matter microstructure and treatment response of late-life depression: a preliminary study. Am J Psychiatry 159: 1929-1932.
4. Alexopoulos GS, Kiosses DN, Klimstra S, Kalayam B, Bruce ML (2002b). Clinical presentation of the 'depression-executive dysfunction syndrome of late life. Am J Geriatr Psychiatry 10: 98-102.
5. Alexopoulos GS, Meyers BS, Young RC, Campbell S, Sibersweig D, Charlson M (1997a). The 'vascular depression' hypothesis. Arch Gen Psychiatry 54: 915-922.
6. Alexopoulos GS, Meyers BS, Young RC, Kakuma T, Silbersweig D, Charlson M (1997b). Clinically defined vascular depression. Am J Psychiatry 154: 562-565.
7. Alexopoulos GS, Meyers BS, Young RC, Kalayam B, Kakuma T, Gabriele M et al (2000). Executive dysfunction and long-term outcomes of geriatric depression. Arch Gen Psychiatry 57: 285-290.
8. American Psychiatric Association. Committee on Nomenclature and Statistics (1994). Diagnostic and Statistical Manual of Mental Disorders, 4th edn. (DSM-IV) American Psychiatric Association: Washington, DC.
9. Bezchlibnyk-Butler K, Aleksic I, Kennedy SH (2000). Citalopram. A review of pharmacological and clinical effects. J Psychiatry Neurosci 25: 241-254.
10. Boone KB, Miller BL, Lesser IM, Merhinger CM, Hill-Gutierrez E, Goldberg M et al (1992). Neuropsychological correlates of white matter lesions in healthy elderly subjects. Arch Neurol 49: 549-554.
11. Bush G, Luu P, Posner MI (2000). Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci 4: 215-222.
12. Butters MA, Becker JT, Nebes RD, Zmuda MD, Mulsant BH, Pollock BG et al (2000). Changes in cognitive functioning following treatment of late-life depression. Am J Psychiatry 157: 1949-1954.
13. Davidson RJ, Pizzagalli D, Nitschke JB, Putnam K (2002). Depression: perspectives from affective neuroscience. Annu Rev Psychol 53: 545-574.
14. de Asis JM, Stern E, Alexopoulos GS, Pan H, Gorp WV, Blumberg H et al (2001). Hippocampal and anterior cingulate activation deficits in patients with geriatric depression. Am J Psychiatry 158: 1321-1323.
15. Drevets WC (1998). Functional neuroimaging studies of depression: the anatomy of melancholia. Annu Rev Med 49: 341-361.
16. Drevets WC (2000). Neuroimaging studies of mood disorders. Biol Psychiatry 48: 813-819.
17. Dunkin JJ, Leuchter AF, Cook IA, Kasl-Godley JE, Abrams M, Rosenberg-Thompson S (2000). Executive dysfunction predicts nonresponse to fluoxetine in major depression. J Affect Disord 60: 13-23.
18. Elderkin-Thompson V, Kumar A, Bilker WB, Dunkin JJ, Mintz J, Moberg PJ et al (2003). Neuropsychological deficits among patients with late-onset minor and major depression. Arch Clin Neuropsychol 18: 529-549.
19. Folstein MF, Folstein SE, McHugh PR (1975). 'Mini-mental state'. J Psychiatric Res 12: 189-198.
20. Frith CD, Friston KJ, Liddle PF, Frackowiak RSJ (1991). A PET study of word finding. Neuropsychologia 12: 1137-1148.
21. Golden CJ (1978). The Stroop Color and Word Test (Manual). Stoetling: Chicago.
22. Hamilton M (1960). A rating scale for depression. J Neurol Neurosurg Psychiatry 23: 56-62.
23. Hickie I, Scott E, Mitchell P, Wilhelm K, Austin MP, Bennett B (1995). Subcortical hyperintensities on magnetic resonance imaging: clinical correlates and prognostic significance in patients with severe depression. Biol Psychiatry 37: 151-160.
24. Hickie I, Scott E, Wilhelm K, Brodaty H (1997). Subcortical hyperintensities on magnetic resonance imaging in patients with severe depression - a longitudinal evaluation. Biol Psychiatry 42: 367-374.
25. Hikosaka SK, Miyauchi S, Takino R, Sasaki Y, Putz B (1998). Transition of brain activation from frontal to parietal areas in visuomotor sequence learning. J Neurosci 18: 1827-1840.
26. Judd LL, Akiskal HS, Maser JD, Zeller PJ, Endicott J, Coryell W et al (1996). Major depressive disorder: a prospective study of residual subthreshold depressive symptoms as predictor of rapid relapse. J Affect Disord 50: 97-108.
27. Jueptner M, Stephan KM, Frith CD, Brooks DJ, Frackowiak RSJ, Passingham RE (1997). Anatomy of motor learning. I. Frontal cortex and attention to action. J Neurophysiol 77: 1313-1324.
28. Kalayam B, Alexopoulos G (1999). Prefrontal dysfunction and treatment response in geriatric depression. Arch Gen Psychiatry 56: 713-718.
29. Kalayam B, Alexopoulos GS (2003). Left frontal error negativity and symptom improvement in geriatric depression: a preliminary study. Am J Psychiatry 160: 2054-2056.
30. Krishnan KRR (1993). Neuroanatomic substrates of depression in the elderly. J Geriatr Psychiatry Neurol 1: 39-58.
31. Krishnan KRR, Hays JC, Blazer DG (1997). MRI-defined vascular depression. Am J Psychiatry 154: 497-500.
32. Lawton MP, Moss M, Fulcomer M, Kleban MH (1982). A research and services oriented Multilevel Assessment Instrument. J Gerontol 37: 91-99.
33. Lecrubier Y (2002). How do you define remission? Acta Psychiatr Scand Suppl 415: 7-11.
34. Lockwood CA, Alexopoulos GS, van Gorp WG (2002). Executive dysfunction in geriatric depression. Am J Psychiatry 159: 1119-1126.
35. Mattis S (1989). Dementia Rating Scale. Psychological Assessment Resources: Odessa, FL.
36. Mayberg HS (1997). Limbic-cortical dysregulation. A proposed model of depression. J Neuropsychiatry Clin Neurosci 9: 471-481.
37. Mayberg HS, Brannan SK, Mahurin RK, Jerabek PA, Brickman JS, Tekell JL et al (1997). Cingulate function in depression: a potential predictor of treatment response. NeuroReport 8: 1057-1061.
38. Mayberg HS, Solomon DH (1995). Depression in Parkinson's disease: a biochemical and organic viewpoint, in behavioral neurology of movement disorders. In: Weiner WJ, Lang AE (eds). Advances in Neurology, Vol. 65. Raven Press: New York. pp 49-60.
39. Miller MD, Paradis CF, Houck PR, Mazumdar S, Stack JA, Rifai AH et al (1992). Rating chronic medical burden in geropsychiatric practice and research: application on the Cumulative Illness Rating Scale. Psychiatry Res 41: 237-248.
40. Mintz J, Mintz LI, Arruda MJ, Hwang SS (1992). Treatments of depression and the functional capacity to work. Arch Gen Psychiatry 49: 761-768.
41. Nebes RD, Butters MA, Houck PR, Zmuda MD, Aizenstein H, Pollock BG et al (2001). Dual-task performance in depressed geriatric patients. Psychiatry Res 102: 139-151.
42. Nebes RD, Pollock BG, Houck PR, Butters MA, Mulsant BH, Zmuda MD et al (2003). Persistence of cognitive impairment in geriatric patients following antidepressant treatment: a randomized, double-blind clinical trial with nortriptyline and paroxetine. J Psychiatr Res 37: 99-108.
43. O'Brien J, Ames D, Chiu E, Schweitzer I, Desmond P, Tress B (1998). Severe deep white matter lesions and outcome in elderly patients with major depressive disorder: follow-up study. BMJ 317: 982-984.
44. Paolo AM, Troster AI, Glatt SL, Hubble JP, Koller WC (1995). Differentiation of Alzheimer's and Parkinson's disease with the Dementia Rating Scale. J Geriatr Psychiatry Neurol 8: 184-188.
45. Paykel ES, Ramana R, Cooper Z, Hayhurst H, Kerr J, Barocka A (1995). Residual symptoms after partial remission: an important outcome in depression. Psychol Med 25: 1171-1180.
46. Pizzagalli D, Pascual-Marqui RD, Nitschke JB, Oakes TR, Larson CL, Abercrombie HC et al (2001). Anterior cingulate activity as a predictor of degree of treatment response in major depression: evidence from brain electrical tomography analysis. Am J Psychiatry 158: 405-415.
47. Rosser AF, Hodges JR (1994). The Dementia Rating Scale in Alzheimer's disease, Huntington's disease and progressive supranuclear palsy. J Neurol 241: 531-536.
48. Simpson S, Baldwin RC, Jackson A, Burns AS (1998). Is subcortical disease associated with poor response to antidepressants? Neurological, neuropsychological and neuroradiological findings in late-life depression. Psychol Med 28: 1015-1026.
49. Sobin C, Sackeim HA (1997). Psychomotor symptoms of depression. Am J Psychiatry 154: 4-17.
50. Spitzer R, Endicott J, Robins E (1978). Research diagnostic criteria. Arch Gen Psychiatry 35: 773-782.
51. Spitzer RL, Endicott J (1975). Schedule for Affective Disorders and Schizophrenia-Lifetime Version. Biometrics Research Department. New York State Psychiatric Institute: New York, NY.
52. Spitzer RL, Williams JBW (1995). Structured Clinical Interview for DSM-IV Patient Version. Biometrics Research Department. New York State Psychiatric Institute: New York.
53. Starkstein SE, Robinson RG, Berthier ML, Price TR (1988). Depressive disorders following posterior circulation as compared with middle cerebral artery infarcts. Brain 111: 375-387.
54. Steffens DC, Conway CR, Dombeck CB, Wagner HR, Tupler LA, Weiner RD (2001). Severity of subcortical gray matter hyperintensity predicts ECT response in geriatric depression. J ECT 158: 405-415.
55. Thase ME, Entsuah AR, Rudolph RL (2001). Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors. Br J Psychiatry 178: 234-241.