(-)-Epigallocatechin gallate, the most active polyphenolic catechin in green tea, presynaptically facilitates Ca2+-dependent glutamate release via activation of protein kinase C in rat cerebral cortex

Synapse

Volumn 61, Issue 11, 2007, Pages 889-902

  Chou, Chien Wen ^a   Huang, Wei Jan ^b   Tien, Lu Tai ^c   Wang, Su Jane ^c  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^c FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

Cerebrocortical synaptosomes; EGCG; Glutamate exocytosis; Protein kinase C; Voltage dependent Ca2+ channel

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 4 AMINOPYRIDINE; BAFILOMYCIN A1; CALCIUM CHANNEL; CALCIUM CHANNEL N TYPE; CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; CALCIUM ION; CYTOCHALASIN D; EPIGALLOCATECHIN GALLATE; GLUTAMIC ACID; GREEN TEA EXTRACT; MARCKS PROTEIN; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN SYNAPTOSOME; CALCIUM TRANSPORT; COGNITION; COGNITIVE DEFECT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVATION; EXOCYTOSIS; MALE; NEUROTRANSMITTER RELEASE; NONHUMAN; PRESYNAPTIC MEMBRANE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; RAT; TEA;

4-AMINOPYRIDINE; ANALYSIS OF VARIANCE; ANIMALS; CALCIUM; CATECHIN; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME ACTIVATION; ENZYME INHIBITORS; GLUTAMIC ACID; MALE; MEMBRANE POTENTIALS; POTASSIUM CHANNEL BLOCKERS; PRESYNAPTIC TERMINALS; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; SYNAPTOSOMES;

EID: 34648820004     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20444     Document Type: Article

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