메뉴 건너뛰기




Volumn 78, Issue 2, 2007, Pages 149-158

Insulin's 85th anniversary-An enduring medical miracle

Author keywords

Analogues; Delivery; Device; Insulin

Indexed keywords

GLUCOSE; HUMALOG MIX; INSULIN; INSULIN ASPART; INSULIN DETEMIR; INSULIN GLARGINE; INSULIN GLULISINE; INSULIN LISPRO; INSULIN ZINC SUSPENSION; ISOPHANE INSULIN; UNCLASSIFIED DRUG;

EID: 34548847731     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabres.2007.04.001     Document Type: Review
Times cited : (60)

References (102)
  • 3
    • 14944366523 scopus 로고
    • The history of insulin
    • Bliss M. The history of insulin. Diabetes Care 16 Suppl. 3 (1993) 4-7
    • (1993) Diabetes Care , vol.16 , Issue.SUPPL. 3 , pp. 4-7
    • Bliss, M.1
  • 4
    • 50749118593 scopus 로고
    • The internal secretion of the pancreas
    • Banting F., and Best C. The internal secretion of the pancreas. J. Lab. Clin. Med. 7 (1922) 251-266
    • (1922) J. Lab. Clin. Med. , vol.7 , pp. 251-266
    • Banting, F.1    Best, C.2
  • 5
    • 0029740605 scopus 로고    scopus 로고
    • Human insulin: basic sciences to therapeutic uses
    • Chien Y.W. Human insulin: basic sciences to therapeutic uses. Drug Dev. Ind. Pharm. 22 (1996) 752-789
    • (1996) Drug Dev. Ind. Pharm. , vol.22 , pp. 752-789
    • Chien, Y.W.1
  • 6
    • 77049230761 scopus 로고
    • The disulphide bonds of insulin
    • Ryle A., Sanger F., Smith L., and Kitai R. The disulphide bonds of insulin. Biochem. J. 60 4 (1955) 541-556
    • (1955) Biochem. J. , vol.60 , Issue.4 , pp. 541-556
    • Ryle, A.1    Sanger, F.2    Smith, L.3    Kitai, R.4
  • 7
    • 0036812235 scopus 로고    scopus 로고
    • The first sequence. Fred Sanger and insulin
    • Stretton A.O. The first sequence. Fred Sanger and insulin. Genetics 162 2 (2002) 527-532
    • (2002) Genetics , vol.162 , Issue.2 , pp. 527-532
    • Stretton, A.O.1
  • 8
    • 0000380542 scopus 로고
    • Immunoassay of endogenous plasma insulin in man 216
    • Yalow R.S., and Berson S.A. Immunoassay of endogenous plasma insulin in man 216. J. Clin. Invest. 39 (1960) 1157-1175
    • (1960) J. Clin. Invest. , vol.39 , pp. 1157-1175
    • Yalow, R.S.1    Berson, S.A.2
  • 9
    • 0016416257 scopus 로고
    • The impact of August Krogh on the insulin treatment of diabetes and our present status
    • Poulsen J.E. The impact of August Krogh on the insulin treatment of diabetes and our present status. Acta Med. Scand. Suppl. 578 (1975) 7-14
    • (1975) Acta Med. Scand. Suppl. , vol.578 , pp. 7-14
    • Poulsen, J.E.1
  • 11
    • 34548840911 scopus 로고
    • The effect of zinc salts on the action of insulin
    • Scott D., and Fisher A. The effect of zinc salts on the action of insulin. J. Pharmacol. Exp. Ther. 55 (1935) 206
    • (1935) J. Pharmacol. Exp. Ther. , vol.55 , pp. 206
    • Scott, D.1    Fisher, A.2
  • 12
    • 0021767171 scopus 로고
    • Landmark perspective: protamine insulin. Hagedorn's pioneering contribution to drug delivery in the management of diabetes
    • Felig P. Landmark perspective: protamine insulin. Hagedorn's pioneering contribution to drug delivery in the management of diabetes. J. Am. Med. Assoc. 251 3 (1984) 393-396
    • (1984) J. Am. Med. Assoc. , vol.251 , Issue.3 , pp. 393-396
    • Felig, P.1
  • 13
    • 0015913949 scopus 로고
    • Experiences with monocomponent insulin treatment
    • Korp W., and Levett R.E. Experiences with monocomponent insulin treatment. Wien Klin Wochenschr 85 18 (1973) 326-330
    • (1973) Wien Klin Wochenschr , vol.85 , Issue.18 , pp. 326-330
    • Korp, W.1    Levett, R.E.2
  • 14
    • 0346625571 scopus 로고
    • Insulin antibody production studied quantitatively with a modified radioimmunoassay technique and with radioimmunoelectrophoresis in patients treated with monocomponent (MC) insulin
    • Bruni B., Ricci C., Giolitti A., Osenda M., D'Alberto M., and Turco G.L. Insulin antibody production studied quantitatively with a modified radioimmunoassay technique and with radioimmunoelectrophoresis in patients treated with monocomponent (MC) insulin. J. Nucl. Biol. Med. 17 3 (1973) 123
    • (1973) J. Nucl. Biol. Med. , vol.17 , Issue.3 , pp. 123
    • Bruni, B.1    Ricci, C.2    Giolitti, A.3    Osenda, M.4    D'Alberto, M.5    Turco, G.L.6
  • 15
    • 0011760892 scopus 로고
    • Human insulin and beyond: semi-synthesis and recombinant DNA technology reviewed
    • Pickup J. (Ed), Blackwell Scientific Publications, Oxford
    • Owens D., Vora J., and Dolben J. Human insulin and beyond: semi-synthesis and recombinant DNA technology reviewed. In: Pickup J. (Ed). Biotechnology of Insulin Therapy (1991), Blackwell Scientific Publications, Oxford
    • (1991) Biotechnology of Insulin Therapy
    • Owens, D.1    Vora, J.2    Dolben, J.3
  • 17
    • 0027421638 scopus 로고
    • Research, development, production, and safety of biosynthetic human insulin
    • Chance R.E., and Frank B.H. Research, development, production, and safety of biosynthetic human insulin. Diabetes Care 16 Suppl. 3 (1993) 133-142
    • (1993) Diabetes Care , vol.16 , Issue.SUPPL. 3 , pp. 133-142
    • Chance, R.E.1    Frank, B.H.2
  • 18
    • 0035448570 scopus 로고    scopus 로고
    • Insulins today and beyond
    • Owens D.R., Zinman B., and Bolli G.B. Insulins today and beyond. Lancet 358 9283 (2001) 739-746
    • (2001) Lancet , vol.358 , Issue.9283 , pp. 739-746
    • Owens, D.R.1    Zinman, B.2    Bolli, G.B.3
  • 19
    • 0036701596 scopus 로고    scopus 로고
    • Novel insulins: expanding options in diabetes management
    • Gerich J.E. Novel insulins: expanding options in diabetes management. Am. J. Med. 113 4 (2002) 308-316
    • (2002) Am. J. Med. , vol.113 , Issue.4 , pp. 308-316
    • Gerich, J.E.1
  • 20
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N. Engl. J. Med. 329 (1993) 977-986
    • (1993) N. Engl. J. Med. , vol.329 , pp. 977-986
    • The Diabetes Control and Complications Trial Research Group1
  • 21
    • 0023936777 scopus 로고
    • Monomeric insulins obtained by protein engineering and their medical implications
    • Brange J., Ribel U., Hansen J.F., Dodson G., Hansen M.T., Havelund S., et al. Monomeric insulins obtained by protein engineering and their medical implications. Nature 333 6174 (1988) 679-682
    • (1988) Nature , vol.333 , Issue.6174 , pp. 679-682
    • Brange, J.1    Ribel, U.2    Hansen, J.F.3    Dodson, G.4    Hansen, M.T.5    Havelund, S.6
  • 22
    • 11844250564 scopus 로고    scopus 로고
    • Insulin analogues
    • Hirsch I.B. Insulin analogues. N. Engl. J. Med. 352 2 (2005) 174-183
    • (2005) N. Engl. J. Med. , vol.352 , Issue.2 , pp. 174-183
    • Hirsch, I.B.1
  • 23
    • 0038445842 scopus 로고    scopus 로고
    • Insulin analogues and other developments in insulin therapy for diabetes
    • McAulay V., and Frier B.M. Insulin analogues and other developments in insulin therapy for diabetes. Expert Opin. Pharmacother. 4 7 (2003) 1141-1156
    • (2003) Expert Opin. Pharmacother. , vol.4 , Issue.7 , pp. 1141-1156
    • McAulay, V.1    Frier, B.M.2
  • 24
    • 33746602593 scopus 로고    scopus 로고
    • Advantage of premeal-injected insulin glulisine compared with regular human insulin in subjects with type 1 diabetes
    • Rave K., Klein O., Frick A.D., and Becker R.H. Advantage of premeal-injected insulin glulisine compared with regular human insulin in subjects with type 1 diabetes. Diabetes Care 29 8 (2006) 1812-1817
    • (2006) Diabetes Care , vol.29 , Issue.8 , pp. 1812-1817
    • Rave, K.1    Klein, O.2    Frick, A.D.3    Becker, R.H.4
  • 25
    • 34548858009 scopus 로고    scopus 로고
    • ® Prescribing Information 2005. Aventis Pharmaceuticals Inc., Kansas City, MO, a member of the sanofi-aventis Group, Bridgewater, NJ.
  • 26
    • 0242269000 scopus 로고    scopus 로고
    • The treat-to-target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients
    • Riddle M.C., Rosenstock J., and Gerich J. The treat-to-target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients. Diabetes Care 26 11 (2003) 3080-3086
    • (2003) Diabetes Care , vol.26 , Issue.11 , pp. 3080-3086
    • Riddle, M.C.1    Rosenstock, J.2    Gerich, J.3
  • 27
    • 2542576404 scopus 로고    scopus 로고
    • Lower within-subject variability of insulin detemir in comparison to NPH insulin and insulin glargine in people with type 1 diabetes
    • Heise T., Nosek L., Ronn B.B., Endahl L., Heinemann L., Kapitza C., et al. Lower within-subject variability of insulin detemir in comparison to NPH insulin and insulin glargine in people with type 1 diabetes. Diabetes 53 6 (2004) 1614-1620
    • (2004) Diabetes , vol.53 , Issue.6 , pp. 1614-1620
    • Heise, T.1    Nosek, L.2    Ronn, B.B.3    Endahl, L.4    Heinemann, L.5    Kapitza, C.6
  • 28
    • 33746538357 scopus 로고    scopus 로고
    • Twice-daily compared with once-daily insulin glargine in people with Type 1 diabetes using meal-time insulin aspart
    • Ashwell S.G., Gebbie J., and Home P.D. Twice-daily compared with once-daily insulin glargine in people with Type 1 diabetes using meal-time insulin aspart. Diabet Med 23 8 (2006) 879-886
    • (2006) Diabet Med , vol.23 , Issue.8 , pp. 879-886
    • Ashwell, S.G.1    Gebbie, J.2    Home, P.D.3
  • 29
    • 4344701890 scopus 로고    scopus 로고
    • The mechanism of protraction of insulin detemir, a long-acting, acylated analog of human insulin
    • Havelund S., Plum A., Ribel U., Jonassen I., Volund A., Markussen J., et al. The mechanism of protraction of insulin detemir, a long-acting, acylated analog of human insulin. Pharm. Res. 21 8 (2004) 1498-1504
    • (2004) Pharm. Res. , vol.21 , Issue.8 , pp. 1498-1504
    • Havelund, S.1    Plum, A.2    Ribel, U.3    Jonassen, I.4    Volund, A.5    Markussen, J.6
  • 30
    • 0029619489 scopus 로고
    • Albumin binding of insulins acylated with fatty acids: characterization of the ligand-protein interaction and correlation between binding affinity and timing of the insulin effect in vivo
    • Kurtzhals P., Havelund S., Jonassen I., Kiehr B., Larsen U.D., Ribel U., et al. Albumin binding of insulins acylated with fatty acids: characterization of the ligand-protein interaction and correlation between binding affinity and timing of the insulin effect in vivo. Biochem. J. 312 Pt 3 (1995) 725-731
    • (1995) Biochem. J. , vol.312 , Issue.PART 3 , pp. 725-731
    • Kurtzhals, P.1    Havelund, S.2    Jonassen, I.3    Kiehr, B.4    Larsen, U.D.5    Ribel, U.6
  • 31
    • 0038114440 scopus 로고    scopus 로고
    • Duration of action, pharmacodynamic profile and between-subject variability of insulin detemir in subjects with type 1 diabetes
    • Pieber T., Plank J., Goerzer E., Sommer R., Wutte A., Sinner F., et al. Duration of action, pharmacodynamic profile and between-subject variability of insulin detemir in subjects with type 1 diabetes. Diabetes 51 Suppl. 2 (2002) A53
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 2
    • Pieber, T.1    Plank, J.2    Goerzer, E.3    Sommer, R.4    Wutte, A.5    Sinner, F.6
  • 32
    • 34548857453 scopus 로고    scopus 로고
    • An evaluation of insulin detemir treatment in type 1 and type 2 diabetes: German cohort data from the PREDICTIVE™ study
    • Lüddeke H.-J., Hansen J., Meriläinen M., and Gallwitz B. An evaluation of insulin detemir treatment in type 1 and type 2 diabetes: German cohort data from the PREDICTIVE™ study. Diabetologia 49 Suppl. 1 (2006) 596-597
    • (2006) Diabetologia , vol.49 , Issue.SUPPL. 1 , pp. 596-597
    • Lüddeke, H.-J.1    Hansen, J.2    Meriläinen, M.3    Gallwitz, B.4
  • 33
    • 0033060426 scopus 로고    scopus 로고
    • Comparative pharmacokinetics and pharmacodynamics of the novel rapid-acting insulin analogue, insulin aspart, in healthy volunteers
    • Home P.D., Barriocanal L., and Lindholm A. Comparative pharmacokinetics and pharmacodynamics of the novel rapid-acting insulin analogue, insulin aspart, in healthy volunteers. Eur. J. Clin. Pharmacol. 55 3 (1999) 199-203
    • (1999) Eur. J. Clin. Pharmacol. , vol.55 , Issue.3 , pp. 199-203
    • Home, P.D.1    Barriocanal, L.2    Lindholm, A.3
  • 34
    • 0034109079 scopus 로고    scopus 로고
    • Use of insulin aspart, a fast-acting insulin analog, as the mealtime insulin in the management of patients with type 1 diabetes
    • Raskin P., Guthrie R.A., Leiter L., Riis A., and Jovanovic L. Use of insulin aspart, a fast-acting insulin analog, as the mealtime insulin in the management of patients with type 1 diabetes. Diabetes Care 23 5 (2000) 583-588
    • (2000) Diabetes Care , vol.23 , Issue.5 , pp. 583-588
    • Raskin, P.1    Guthrie, R.A.2    Leiter, L.3    Riis, A.4    Jovanovic, L.5
  • 35
    • 0033766190 scopus 로고    scopus 로고
    • A 16-week comparison of the novel insulin analog insulin glargine (HOE 901) and NPH human insulin used with insulin lispro in patients with type 1 diabetes
    • Raskin P., Klaff L., Bergenstal R., Halle J.P., Donley D., and Mecca T. A 16-week comparison of the novel insulin analog insulin glargine (HOE 901) and NPH human insulin used with insulin lispro in patients with type 1 diabetes. Diabetes Care 23 11 (2000) 1666-1671
    • (2000) Diabetes Care , vol.23 , Issue.11 , pp. 1666-1671
    • Raskin, P.1    Klaff, L.2    Bergenstal, R.3    Halle, J.P.4    Donley, D.5    Mecca, T.6
  • 36
    • 20944440180 scopus 로고    scopus 로고
    • Insulin aspart improves meal time glycaemic control in patients with Type 2 diabetes: a randomized, stratified, double-blind and cross-over trial
    • Perriello G., Pampanelli S., Porcellati F., Avogaro A., Bosi E., Petrella G., et al. Insulin aspart improves meal time glycaemic control in patients with Type 2 diabetes: a randomized, stratified, double-blind and cross-over trial. Diabet. Med. 22 5 (2005) 606-611
    • (2005) Diabet. Med. , vol.22 , Issue.5 , pp. 606-611
    • Perriello, G.1    Pampanelli, S.2    Porcellati, F.3    Avogaro, A.4    Bosi, E.5    Petrella, G.6
  • 37
    • 3142697942 scopus 로고    scopus 로고
    • Hypoglycaemia with insulin aspart: a double-blind, randomised, crossover trial in subjects with type 1 diabetes
    • Heller S.R., Colagiuri S., Vaaler S., Wolffenbuttel B.H., Koelendorf K., Friberg H.H., et al. Hypoglycaemia with insulin aspart: a double-blind, randomised, crossover trial in subjects with type 1 diabetes. Diabet. Med. 21 7 (2004) 769-775
    • (2004) Diabet. Med. , vol.21 , Issue.7 , pp. 769-775
    • Heller, S.R.1    Colagiuri, S.2    Vaaler, S.3    Wolffenbuttel, B.H.4    Koelendorf, K.5    Friberg, H.H.6
  • 38
    • 0032861268 scopus 로고    scopus 로고
    • Effect of the fast-acting insulin analog lispro on the risk of nocturnal hypoglycemia during intensified insulin therapy. U.K. Lispro Study Group
    • Heller S.R., Amiel S.A., and Mansell P. Effect of the fast-acting insulin analog lispro on the risk of nocturnal hypoglycemia during intensified insulin therapy. U.K. Lispro Study Group. Diabetes Care 22 10 (1999) 1607-1611
    • (1999) Diabetes Care , vol.22 , Issue.10 , pp. 1607-1611
    • Heller, S.R.1    Amiel, S.A.2    Mansell, P.3
  • 39
    • 33645054809 scopus 로고    scopus 로고
    • Improved glycaemic control with insulin glargine plus insulin lispro: a multicentre, randomized, cross-over trial in people with type 1 diabetes
    • Ashwell S.G., Amiel S.A., Bilous R.W., Dashora U., Heller S.R., Hepburn D.A., et al. Improved glycaemic control with insulin glargine plus insulin lispro: a multicentre, randomized, cross-over trial in people with type 1 diabetes. Diabet. Med. 23 3 (2006) 285-292
    • (2006) Diabet. Med. , vol.23 , Issue.3 , pp. 285-292
    • Ashwell, S.G.1    Amiel, S.A.2    Bilous, R.W.3    Dashora, U.4    Heller, S.R.5    Hepburn, D.A.6
  • 40
    • 0034203532 scopus 로고    scopus 로고
    • Pharmacokinetics of 125I-labeled insulin glargine (HOE 901) in healthy men: comparison with NPH insulin and the influence of different subcutaneous injection sites
    • Owens D.R., Coates P.A., Luzio S.D., Tinbergen J.P., and Kurzhals R. Pharmacokinetics of 125I-labeled insulin glargine (HOE 901) in healthy men: comparison with NPH insulin and the influence of different subcutaneous injection sites. Diabetes Care 23 6 (2000) 813-819
    • (2000) Diabetes Care , vol.23 , Issue.6 , pp. 813-819
    • Owens, D.R.1    Coates, P.A.2    Luzio, S.D.3    Tinbergen, J.P.4    Kurzhals, R.5
  • 41
    • 20944432717 scopus 로고    scopus 로고
    • A double-blind, randomized, dose-response study investigating the pharmacodynamic and pharmacokinetic properties of the long-acting insulin analog detemir
    • Plank J., Bodenlenz M., Sinner F., Magnes C., Gorzer E., Regittnig W., et al. A double-blind, randomized, dose-response study investigating the pharmacodynamic and pharmacokinetic properties of the long-acting insulin analog detemir. Diabetes Care 28 5 (2005) 1107-1112
    • (2005) Diabetes Care , vol.28 , Issue.5 , pp. 1107-1112
    • Plank, J.1    Bodenlenz, M.2    Sinner, F.3    Magnes, C.4    Gorzer, E.5    Regittnig, W.6
  • 42
    • 2442678007 scopus 로고    scopus 로고
    • Insulin analogues (insulin detemir and insulin aspart) versus traditional human insulins (NPH insulin and regular human insulin) in basal-bolus therapy for patients with type 1 diabetes
    • Hermansen K., Fontaine P., Kukolja K.K., Peterkova V., Leth G., and Gall M.A. Insulin analogues (insulin detemir and insulin aspart) versus traditional human insulins (NPH insulin and regular human insulin) in basal-bolus therapy for patients with type 1 diabetes. Diabetologia 47 4 (2004) 622-629
    • (2004) Diabetologia , vol.47 , Issue.4 , pp. 622-629
    • Hermansen, K.1    Fontaine, P.2    Kukolja, K.K.3    Peterkova, V.4    Leth, G.5    Gall, M.A.6
  • 43
    • 33746391488 scopus 로고    scopus 로고
    • A 26-week, randomized, parallel, treat-to-target trial comparing insulin detemir with NPH insulin as add-on therapy to oral glucose-lowering drugs in insulin-naive people with type 2 diabetes
    • Hermansen K., Davies M., Derezinski T., Martinez R.G., Clauson P., and Home P. A 26-week, randomized, parallel, treat-to-target trial comparing insulin detemir with NPH insulin as add-on therapy to oral glucose-lowering drugs in insulin-naive people with type 2 diabetes. Diabetes Care 29 6 (2006) 1269-1274
    • (2006) Diabetes Care , vol.29 , Issue.6 , pp. 1269-1274
    • Hermansen, K.1    Davies, M.2    Derezinski, T.3    Martinez, R.G.4    Clauson, P.5    Home, P.6
  • 44
    • 0035146436 scopus 로고    scopus 로고
    • Comparison of the soluble basal insulin analog insulin detemir with NPH insulin: a randomized open crossover trial in type 1 diabetic subjects on basal-bolus therapy
    • Hermansen K., Madsbad S., Perrild H., Kristensen A., and Axelsen M. Comparison of the soluble basal insulin analog insulin detemir with NPH insulin: a randomized open crossover trial in type 1 diabetic subjects on basal-bolus therapy. Diabetes Care 24 2 (2001) 296-301
    • (2001) Diabetes Care , vol.24 , Issue.2 , pp. 296-301
    • Hermansen, K.1    Madsbad, S.2    Perrild, H.3    Kristensen, A.4    Axelsen, M.5
  • 45
    • 34548859915 scopus 로고    scopus 로고
    • Basal-bolus therapy with insulin detemir/insulin aspart improves glycaemic control and reduces hypoglycaemia: data from the German cohort of the PREDICTIVE™ study
    • Ackermann R., Hansen J., and Nauck M. Basal-bolus therapy with insulin detemir/insulin aspart improves glycaemic control and reduces hypoglycaemia: data from the German cohort of the PREDICTIVE™ study. Diabetologia 49 Suppl. 1 (2006) 595
    • (2006) Diabetologia , vol.49 , Issue.SUPPL. 1 , pp. 595
    • Ackermann, R.1    Hansen, J.2    Nauck, M.3
  • 46
    • 33845980344 scopus 로고    scopus 로고
    • Insulin detemir added to oral anti-diabetic drugs in type 2 diabetes provides glycemic control comparable to insulin glargine with less weight gain
    • Rosenstock J., Davies M., Home P., Larsen J., Tamer S., and Schernthaner G. Insulin detemir added to oral anti-diabetic drugs in type 2 diabetes provides glycemic control comparable to insulin glargine with less weight gain. Diabetes 55 Suppl. 1 (2006) A132
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 1
    • Rosenstock, J.1    Davies, M.2    Home, P.3    Larsen, J.4    Tamer, S.5    Schernthaner, G.6
  • 47
    • 0036096925 scopus 로고    scopus 로고
    • Premixed insulin aspart 30 vs. premixed human insulin 30/70 twice daily: a randomized trial in Type 1 and Type 2 diabetic patients
    • Boehm B.O., Home P.D., Behrend C., Kamp N.M., and Lindholm A. Premixed insulin aspart 30 vs. premixed human insulin 30/70 twice daily: a randomized trial in Type 1 and Type 2 diabetic patients. Diabet Med. 19 5 (2002) 393-399
    • (2002) Diabet Med. , vol.19 , Issue.5 , pp. 393-399
    • Boehm, B.O.1    Home, P.D.2    Behrend, C.3    Kamp, N.M.4    Lindholm, A.5
  • 48
    • 33748549978 scopus 로고    scopus 로고
    • Comparison of insulin lispro mixture 25/75 with insulin glargine during a 24-h standardized test-meal period in patients with type 2 diabetes
    • Roach P., and Malone J.K. Comparison of insulin lispro mixture 25/75 with insulin glargine during a 24-h standardized test-meal period in patients with type 2 diabetes. Diabet Med. 23 7 (2006) 743-749
    • (2006) Diabet Med. , vol.23 , Issue.7 , pp. 743-749
    • Roach, P.1    Malone, J.K.2
  • 49
    • 33646014162 scopus 로고    scopus 로고
    • Attainment of glycaemic goals in type 2 diabetes with once-, twice-, or thrice-daily dosing with biphasic insulin aspart 70/30 (The 1-2-3 study)
    • Garber A.J., Wahlen J., Wahl T., Bressler P., Braceras R., Allen E., et al. Attainment of glycaemic goals in type 2 diabetes with once-, twice-, or thrice-daily dosing with biphasic insulin aspart 70/30 (The 1-2-3 study). Diabetes Obes. Metab. 8 1 (2006) 58-66
    • (2006) Diabetes Obes. Metab. , vol.8 , Issue.1 , pp. 58-66
    • Garber, A.J.1    Wahlen, J.2    Wahl, T.3    Bressler, P.4    Braceras, R.5    Allen, E.6
  • 50
    • 33646554847 scopus 로고    scopus 로고
    • Comparative efficacy of glimepiride and/or metformin with insulin in type 2 diabetes
    • Kabadi U.M., and Kabadi M. Comparative efficacy of glimepiride and/or metformin with insulin in type 2 diabetes. Diabetes Res. Clin. Pract. 72 3 (2006) 265-270
    • (2006) Diabetes Res. Clin. Pract. , vol.72 , Issue.3 , pp. 265-270
    • Kabadi, U.M.1    Kabadi, M.2
  • 51
    • 17144389381 scopus 로고    scopus 로고
    • Twice-daily pre-mixed insulin rather than basal insulin therapy alone results in better overall glycaemic control in patients with Type 2 diabetes
    • Malone J.K., Bai S., Campaigne B.N., Reviriego J., and ugendre-Ferrante B. Twice-daily pre-mixed insulin rather than basal insulin therapy alone results in better overall glycaemic control in patients with Type 2 diabetes. Diabet. Med. 22 4 (2005) 374-381
    • (2005) Diabet. Med. , vol.22 , Issue.4 , pp. 374-381
    • Malone, J.K.1    Bai, S.2    Campaigne, B.N.3    Reviriego, J.4    ugendre-Ferrante, B.5
  • 53
    • 0033569317 scopus 로고    scopus 로고
    • Insulin delivery using pen devices. Simple-to-use tools may help young and old alike
    • 68
    • Bohannon N.J. Insulin delivery using pen devices. Simple-to-use tools may help young and old alike. Postgrad. Med. 106 5 (1999) 57-64 68
    • (1999) Postgrad. Med. , vol.106 , Issue.5 , pp. 57-64
    • Bohannon, N.J.1
  • 54
    • 0029085416 scopus 로고
    • Safety, efficacy, acceptability of a pre-filled insulin pen in diabetic patients over 60 years old
    • Coscelli C., Lostia S., Lunetta M., Nosari I., and Coronel G.A. Safety, efficacy, acceptability of a pre-filled insulin pen in diabetic patients over 60 years old. Diabetes Res. Clin. Pract. 28 3 (1995) 173-177
    • (1995) Diabetes Res. Clin. Pract. , vol.28 , Issue.3 , pp. 173-177
    • Coscelli, C.1    Lostia, S.2    Lunetta, M.3    Nosari, I.4    Coronel, G.A.5
  • 55
    • 0027475965 scopus 로고
    • A comparative study between two insulin pen injection devices
    • Smits J., Schop C., and Blok G. A comparative study between two insulin pen injection devices. Acta Therapeutica 19 (1993) 15-22
    • (1993) Acta Therapeutica , vol.19 , pp. 15-22
    • Smits, J.1    Schop, C.2    Blok, G.3
  • 56
    • 0022398568 scopus 로고
    • A multiple injection regimen using an insulin injection pen and pre-filled cartridged soluble human insulin in adolescents with diabetes
    • Jefferson I.G., Marteau T.M., Smith M.A., and Baum J.D. A multiple injection regimen using an insulin injection pen and pre-filled cartridged soluble human insulin in adolescents with diabetes. Diabet. Med. 2 6 (1985) 493-495
    • (1985) Diabet. Med. , vol.2 , Issue.6 , pp. 493-495
    • Jefferson, I.G.1    Marteau, T.M.2    Smith, M.A.3    Baum, J.D.4
  • 57
    • 0027223191 scopus 로고
    • Use of a prefilled insulin syringe (Novolin Prefilled) by patients with diabetes
    • Plevin S., and Sadur C. Use of a prefilled insulin syringe (Novolin Prefilled) by patients with diabetes. Clin. Ther. 15 2 (1993) 423-431
    • (1993) Clin. Ther. , vol.15 , Issue.2 , pp. 423-431
    • Plevin, S.1    Sadur, C.2
  • 58
    • 0031878264 scopus 로고    scopus 로고
    • Assessment by patients with diabetes mellitus of two insulin pen delivery systems versus a vial and syringe
    • Graff M.R., and McClanahan M.A. Assessment by patients with diabetes mellitus of two insulin pen delivery systems versus a vial and syringe. Clin. Ther. 20 3 (1998) 486-496
    • (1998) Clin. Ther. , vol.20 , Issue.3 , pp. 486-496
    • Graff, M.R.1    McClanahan, M.A.2
  • 59
    • 0017834105 scopus 로고
    • Continuous subcutaneous insulin infusion: an approach to achieving normoglycaemia
    • Pickup J.C., Keen H., Parsons J.A., and Alberti K.G. Continuous subcutaneous insulin infusion: an approach to achieving normoglycaemia. Br. Med. J. 1 6107 (1978) 204-207
    • (1978) Br. Med. J. , vol.1 , Issue.6107 , pp. 204-207
    • Pickup, J.C.1    Keen, H.2    Parsons, J.A.3    Alberti, K.G.4
  • 60
    • 0006027883 scopus 로고    scopus 로고
    • Continuous subcutaneous insulin infusion
    • Pickup J., and Williams G. (Eds), Blackwell Science, Oxford 34.1-34.12
    • Pickup J. Continuous subcutaneous insulin infusion. In: Pickup J., and Williams G. (Eds). Textbook of Diabetes (1997), Blackwell Science, Oxford 34.1-34.12
    • (1997) Textbook of Diabetes
    • Pickup, J.1
  • 61
    • 0018772709 scopus 로고
    • Reduction to normal of plasma glucose in juvenile diabetes by subcutaneous administration of insulin with a portable infusion pump
    • Tamborlane W.V., Sherwin R.S., Genel M., and Felig P. Reduction to normal of plasma glucose in juvenile diabetes by subcutaneous administration of insulin with a portable infusion pump. N. Engl. J. Med. 300 11 (1979) 573-578
    • (1979) N. Engl. J. Med. , vol.300 , Issue.11 , pp. 573-578
    • Tamborlane, W.V.1    Sherwin, R.S.2    Genel, M.3    Felig, P.4
  • 62
    • 0029912364 scopus 로고    scopus 로고
    • Reduction in severe hypoglycemia with long-term continuous subcutaneous insulin infusion in type I diabetes
    • Bode B.W., Steed R.D., and Davidson P.C. Reduction in severe hypoglycemia with long-term continuous subcutaneous insulin infusion in type I diabetes. Diabetes Care 19 4 (1996) 324-327
    • (1996) Diabetes Care , vol.19 , Issue.4 , pp. 324-327
    • Bode, B.W.1    Steed, R.D.2    Davidson, P.C.3
  • 63
    • 0022444971 scopus 로고
    • Hypoglycemia and counterregulation in insulin-dependent diabetic patients: a comparison of continuous subcutaneous insulin infusion and conventional insulin injection therapy
    • Ng Tang F.S., Pickup J.C., Bending J.J., Collins A.C., Keen H., and Dalton N. Hypoglycemia and counterregulation in insulin-dependent diabetic patients: a comparison of continuous subcutaneous insulin infusion and conventional insulin injection therapy. Diabetes Care 9 3 (1986) 221-227
    • (1986) Diabetes Care , vol.9 , Issue.3 , pp. 221-227
    • Ng Tang, F.S.1    Pickup, J.C.2    Bending, J.J.3    Collins, A.C.4    Keen, H.5    Dalton, N.6
  • 64
    • 0022613411 scopus 로고
    • Pathogenesis and prevention of the dawn phenomenon in diabetic patients treated with CSII
    • Koivisto V.A., Yki-Jarvinen H., Helve E., Karonen S.L., and Pelkonen R. Pathogenesis and prevention of the dawn phenomenon in diabetic patients treated with CSII. Diabetes 35 1 (1986) 78-82
    • (1986) Diabetes , vol.35 , Issue.1 , pp. 78-82
    • Koivisto, V.A.1    Yki-Jarvinen, H.2    Helve, E.3    Karonen, S.L.4    Pelkonen, R.5
  • 65
    • 0036093381 scopus 로고    scopus 로고
    • Insulin pump therapy in the 21st century. Strategies for successful use in adults, adolescents, and children with diabetes
    • Bode B.W., Tamborlane W.V., and Davidson P.C. Insulin pump therapy in the 21st century. Strategies for successful use in adults, adolescents, and children with diabetes. Postgrad. Med. 111 5 (2002) 69-77
    • (2002) Postgrad. Med. , vol.111 , Issue.5 , pp. 69-77
    • Bode, B.W.1    Tamborlane, W.V.2    Davidson, P.C.3
  • 66
    • 18144421498 scopus 로고    scopus 로고
    • Continuous glucose monitoring: roadmap for 21st century diabetes therapy
    • Klonoff D.C. Continuous glucose monitoring: roadmap for 21st century diabetes therapy. Diabetes Care 28 5 (2005) 1231-1239
    • (2005) Diabetes Care , vol.28 , Issue.5 , pp. 1231-1239
    • Klonoff, D.C.1
  • 67
    • 0042490765 scopus 로고    scopus 로고
    • The continuous glucose monitoring system is useful for detecting unrecognized hypoglycemias in patients with type 1 and type 2 diabetes but is not better than frequent capillary glucose measurements for improving metabolic control
    • Chico A., Vidal-Rios P., Subira M., and Novials A. The continuous glucose monitoring system is useful for detecting unrecognized hypoglycemias in patients with type 1 and type 2 diabetes but is not better than frequent capillary glucose measurements for improving metabolic control. Diabetes Care 26 4 (2003) 1153-1157
    • (2003) Diabetes Care , vol.26 , Issue.4 , pp. 1153-1157
    • Chico, A.1    Vidal-Rios, P.2    Subira, M.3    Novials, A.4
  • 68
    • 33646050618 scopus 로고    scopus 로고
    • Value and limitations of the Continuous Glucose Monitoring System in the management of type 1 diabetes
    • Melki V., Ayon F., Fernandez M., and Hanaire-Broutin H. Value and limitations of the Continuous Glucose Monitoring System in the management of type 1 diabetes. Diabetes Metab. 32 2 (2006) 123-129
    • (2006) Diabetes Metab. , vol.32 , Issue.2 , pp. 123-129
    • Melki, V.1    Ayon, F.2    Fernandez, M.3    Hanaire-Broutin, H.4
  • 69
    • 9644275397 scopus 로고    scopus 로고
    • Use of the Continuous Glucose Monitoring System to guide therapy in patients with insulin-treated diabetes: a randomized controlled trial
    • Tanenberg R., Bode B., Lane W., Levetan C., Mestman J., Harmel A.P., et al. Use of the Continuous Glucose Monitoring System to guide therapy in patients with insulin-treated diabetes: a randomized controlled trial. Mayo Clin. Proc. 79 12 (2004) 1521-1526
    • (2004) Mayo Clin. Proc. , vol.79 , Issue.12 , pp. 1521-1526
    • Tanenberg, R.1    Bode, B.2    Lane, W.3    Levetan, C.4    Mestman, J.5    Harmel, A.P.6
  • 70
    • 18144373420 scopus 로고    scopus 로고
    • A Randomized Multicenter Trial Comparing the GlucoWatch Biographer With Standard Glucose Monitoring in Children With Type 1 Diabetes
    • The Diabetes Research in Children Network (DirecNet) Study Group. A Randomized Multicenter Trial Comparing the GlucoWatch Biographer With Standard Glucose Monitoring in Children With Type 1 Diabetes. Diabetes Care 28 5 (2005) 1101-1106
    • (2005) Diabetes Care , vol.28 , Issue.5 , pp. 1101-1106
    • The Diabetes Research in Children Network (DirecNet) Study Group1
  • 71
    • 33645051466 scopus 로고    scopus 로고
    • Continuous glucose monitoring and closed-loop systems
    • Hovorka R. Continuous glucose monitoring and closed-loop systems. Diabet. Med. 23 1 (2006) 1-12
    • (2006) Diabet. Med. , vol.23 , Issue.1 , pp. 1-12
    • Hovorka, R.1
  • 72
    • 18144431459 scopus 로고    scopus 로고
    • A Continuous Glucose Monitoring System (CGMS)-a promising approach for improving metabolic control in persons with type 1 diabetes mellitus treated by insulin pumps 863
    • Mlcak P., Fialova J., Trnkova K., and Chlup R. A Continuous Glucose Monitoring System (CGMS)-a promising approach for improving metabolic control in persons with type 1 diabetes mellitus treated by insulin pumps 863. Biomed. Pap. Med. Fac. Univ. Palacky Olomouc. Czech. Repub. 148 1 (2004) 33-38
    • (2004) Biomed. Pap. Med. Fac. Univ. Palacky Olomouc. Czech. Repub. , vol.148 , Issue.1 , pp. 33-38
    • Mlcak, P.1    Fialova, J.2    Trnkova, K.3    Chlup, R.4
  • 74
    • 0025825296 scopus 로고
    • Degradation of insulin by trypsin and alpha-chymotrypsin
    • Schilling R.J., and Mitra A.K. Degradation of insulin by trypsin and alpha-chymotrypsin. Pharm. Res. 8 6 (1991) 721-727
    • (1991) Pharm. Res. , vol.8 , Issue.6 , pp. 721-727
    • Schilling, R.J.1    Mitra, A.K.2
  • 75
    • 0025076529 scopus 로고
    • Overcoming barriers to the oral administration of peptide drugs
    • Davis S.S. Overcoming barriers to the oral administration of peptide drugs. Trends Pharmacol. Sci. 11 9 (1990) 353-355
    • (1990) Trends Pharmacol. Sci. , vol.11 , Issue.9 , pp. 353-355
    • Davis, S.S.1
  • 76
    • 0014341451 scopus 로고
    • Absorption of insulin from the human small intestine
    • Crane C.W., and Luntz G.R. Absorption of insulin from the human small intestine. Diabetes 17 10 (1968) 625-627
    • (1968) Diabetes , vol.17 , Issue.10 , pp. 625-627
    • Crane, C.W.1    Luntz, G.R.2
  • 77
    • 0000786497 scopus 로고
    • Novel routes of insulin delivery
    • Marshall S., and Home P. (Eds), Elsevier, Amsterdam, London, New York, Tokyo
    • Olsen C., Liu G., and Charles A. Novel routes of insulin delivery. In: Marshall S., and Home P. (Eds). The Diabetes Annual/8 (1994), Elsevier, Amsterdam, London, New York, Tokyo 243-276
    • (1994) The Diabetes Annual/8 , pp. 243-276
    • Olsen, C.1    Liu, G.2    Charles, A.3
  • 78
    • 0030981739 scopus 로고    scopus 로고
    • Pharmacokinetic considerations of new insulin formulations and routes of administration
    • Hoffman A., and Ziv E. Pharmacokinetic considerations of new insulin formulations and routes of administration. Clin. Pharmacokinet. 33 4 (1997) 285-301
    • (1997) Clin. Pharmacokinet. , vol.33 , Issue.4 , pp. 285-301
    • Hoffman, A.1    Ziv, E.2
  • 79
    • 0003862740 scopus 로고
    • Berger M., and Gries F.A. (Eds), Thieme Verlag
    • Holman R. In: Berger M., and Gries F.A. (Eds). Frontiers in Insulin Pharmacology (1993), Thieme Verlag 138-142
    • (1993) Frontiers in Insulin Pharmacology , pp. 138-142
    • Holman, R.1
  • 80
    • 0003797934 scopus 로고    scopus 로고
    • Pharmacological reproducibility of inhaled insulin dosed pre-meal in patients with Type 2 DM
    • Gelfand R.A., Schwartz S., Horton M., Law C.G., and Pun E.F.F. Pharmacological reproducibility of inhaled insulin dosed pre-meal in patients with Type 2 DM. Diabetologia 43 Suppl. 1 (2000) A202
    • (2000) Diabetologia , vol.43 , Issue.SUPPL. 1
    • Gelfand, R.A.1    Schwartz, S.2    Horton, M.3    Law, C.G.4    Pun, E.F.F.5
  • 82
    • 33748639228 scopus 로고    scopus 로고
    • Structure of the insulin receptor ectodomain reveals a folded-over conformation
    • McKern N.M., Lawrence M.C., Streltsov V.A., Lou M.Z., Adams T.E., Lovrecz G.O., et al. Structure of the insulin receptor ectodomain reveals a folded-over conformation. Nature 443 7108 (2006) 218-221
    • (2006) Nature , vol.443 , Issue.7108 , pp. 218-221
    • McKern, N.M.1    Lawrence, M.C.2    Streltsov, V.A.3    Lou, M.Z.4    Adams, T.E.5    Lovrecz, G.O.6
  • 83
    • 0026578922 scopus 로고
    • Intranasal administration of insulin with phospholipid as absorption enhancer: pharmacokinetics in normal subjects
    • Drejer K., Vaag A., Bech K., Hansen P., Sorensen A.R., and Mygind N. Intranasal administration of insulin with phospholipid as absorption enhancer: pharmacokinetics in normal subjects. Diabet. Med. 9 4 (1992) 335-340
    • (1992) Diabet. Med. , vol.9 , Issue.4 , pp. 335-340
    • Drejer, K.1    Vaag, A.2    Bech, K.3    Hansen, P.4    Sorensen, A.R.5    Mygind, N.6
  • 84
    • 0023618986 scopus 로고
    • Long-term use of intranasal insulin in insulin-dependent diabetic patients
    • Frauman A.G., Cooper M.E., Parsons B.J., Jerums G., and Louis W.J. Long-term use of intranasal insulin in insulin-dependent diabetic patients. Diabetes Care 10 5 (1987) 573-578
    • (1987) Diabetes Care , vol.10 , Issue.5 , pp. 573-578
    • Frauman, A.G.1    Cooper, M.E.2    Parsons, B.J.3    Jerums, G.4    Louis, W.J.5
  • 86
    • 0027375767 scopus 로고
    • The pharmacodynamics and activity of intranasally administered insulin in healthy male volunteers
    • Jacobs M.A., Schreuder R.H., Jap A.J., Nauta J.J., Andersen P.M., and Heine R.J. The pharmacodynamics and activity of intranasally administered insulin in healthy male volunteers. Diabetes 42 11 (1993) 1649-1655
    • (1993) Diabetes , vol.42 , Issue.11 , pp. 1649-1655
    • Jacobs, M.A.1    Schreuder, R.H.2    Jap, A.J.3    Nauta, J.J.4    Andersen, P.M.5    Heine, R.J.6
  • 87
    • 0021918027 scopus 로고
    • Intranasal aerosolized insulin. Mixed-meal studies and long-term use in type I diabetes
    • Salzman R., Manson J.E., Griffing G.T., Kimmerle R., Ruderman N., McCall A., et al. Intranasal aerosolized insulin. Mixed-meal studies and long-term use in type I diabetes. N. Engl. J. Med. 312 17 (1985) 1078-1084
    • (1985) N. Engl. J. Med. , vol.312 , Issue.17 , pp. 1078-1084
    • Salzman, R.1    Manson, J.E.2    Griffing, G.T.3    Kimmerle, R.4    Ruderman, N.5    McCall, A.6
  • 89
    • 0028967620 scopus 로고
    • Intranasal insulin: the effects of three dose regimens on postprandial glycaemic profiles in type II diabetic subjects
    • Coates P.A., Ismail I.S., Luzio S.D., Griffiths I., Ollerton R.L., Volund A., et al. Intranasal insulin: the effects of three dose regimens on postprandial glycaemic profiles in type II diabetic subjects. Diabet. Med. 12 3 (1995) 235-239
    • (1995) Diabet. Med. , vol.12 , Issue.3 , pp. 235-239
    • Coates, P.A.1    Ismail, I.S.2    Luzio, S.D.3    Griffiths, I.4    Ollerton, R.L.5    Volund, A.6
  • 90
    • 0023244003 scopus 로고
    • Effects of intranasal insulin in non-obese type II diabetics
    • Frauman A.G., Jerums G., and Louis W.J. Effects of intranasal insulin in non-obese type II diabetics. Diabetes Res. Clin. Pract. 3 4 (1987) 197-202
    • (1987) Diabetes Res. Clin. Pract. , vol.3 , Issue.4 , pp. 197-202
    • Frauman, A.G.1    Jerums, G.2    Louis, W.J.3
  • 92
    • 0036969672 scopus 로고    scopus 로고
    • Alternative delivery routes: inhaled insulin
    • Heinemann L. Alternative delivery routes: inhaled insulin. Diabetes Nutr. Metab. 15 6 (2002) 417-422
    • (2002) Diabetes Nutr. Metab. , vol.15 , Issue.6 , pp. 417-422
    • Heinemann, L.1
  • 95
    • 6044257275 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and pharmacodynamics of inhaled insulin
    • Patton J.S., Bukar J.G., and Eldon M.A. Clinical pharmacokinetics and pharmacodynamics of inhaled insulin. Clin. Pharmacokinet. 43 12 (2004) 781-801
    • (2004) Clin. Pharmacokinet. , vol.43 , Issue.12 , pp. 781-801
    • Patton, J.S.1    Bukar, J.G.2    Eldon, M.A.3
  • 96
    • 33747190354 scopus 로고    scopus 로고
    • Diabetes therapy trials with inhaled insulin
    • Fineberg S.E. Diabetes therapy trials with inhaled insulin. Expert Opin. Investig. Drugs 15 7 (2006) 743-762
    • (2006) Expert Opin. Investig. Drugs , vol.15 , Issue.7 , pp. 743-762
    • Fineberg, S.E.1
  • 97
    • 0027506440 scopus 로고
    • Preliminary study of the efficacy of insulin aerosol delivered by oral inhalation in diabetic patients
    • Laube B.L., Georgopoulos A., and Adams III G.K. Preliminary study of the efficacy of insulin aerosol delivered by oral inhalation in diabetic patients. JAMA 269 16 (1993) 2106-2109
    • (1993) JAMA , vol.269 , Issue.16 , pp. 2106-2109
    • Laube, B.L.1    Georgopoulos, A.2    Adams III, G.K.3
  • 98
    • 0035084004 scopus 로고    scopus 로고
    • Dose-response relation of liquid aerosol inhaled insulin in type I diabetic patients
    • Brunner G.A., Balent B., Ellmerer M., Schaupp L., Siebenhofer A., Jendle J.H., et al. Dose-response relation of liquid aerosol inhaled insulin in type I diabetic patients. Diabetologia 44 3 (2001) 305-308
    • (2001) Diabetologia , vol.44 , Issue.3 , pp. 305-308
    • Brunner, G.A.1    Balent, B.2    Ellmerer, M.3    Schaupp, L.4    Siebenhofer, A.5    Jendle, J.H.6
  • 100
    • 0035798916 scopus 로고    scopus 로고
    • Efficacy of inhaled human insulin in type 1 diabetes mellitus: a randomised proof-of-concept study
    • Skyler J.S., Cefalu W.T., Kourides I.A., Landschulz W.H., Balagtas C.C., Cheng S.L., et al. Efficacy of inhaled human insulin in type 1 diabetes mellitus: a randomised proof-of-concept study. Lancet 357 9253 (2001) 331-335
    • (2001) Lancet , vol.357 , Issue.9253 , pp. 331-335
    • Skyler, J.S.1    Cefalu, W.T.2    Kourides, I.A.3    Landschulz, W.H.4    Balagtas, C.C.5    Cheng, S.L.6
  • 101
    • 3042754392 scopus 로고    scopus 로고
    • Inhaled human insulin using the AERx insulin diabetes management system in healthy and asthmatic subjects
    • Adamson U., Rönnemaa T., Petersen A.H., and Hermansen K. Inhaled human insulin using the AERx insulin diabetes management system in healthy and asthmatic subjects. Diabetologia 45 Suppl. 2 (2002) A255-A256
    • (2002) Diabetologia , vol.45 , Issue.SUPPL. 2
    • Adamson, U.1    Rönnemaa, T.2    Petersen, A.H.3    Hermansen, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.