Population pharmacokinetic meta-analysis of trabectedin (ET-743, Yondelis®) in cancer patients

Clinical Pharmacokinetics

Volumn 46, Issue 10, 2007, Pages 867-884

  Perez Ruixo, Juan Jose ^a,b   Zannikos, Peter ^c   Hirankarn, Sarapee ^d   Stuyckens, Kim ^a   Ludwig, Elizabeth A ^d   Soto Matos, Arturo ^e   Lopez Lazaro, Luis ^e   Owen, Joel S ^d  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^b MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^c JANSSEN RESEARCH AND DEVELOPMENT   (United States)

^d Albany Medical College   (United States)

^e PHARMAMAR S A   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; ANTIEMETIC AGENT; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CREATININE; DEXAMETHASONE; LACTATE DEHYDROGENASE; LIVER PROTECTIVE AGENT; PROTEIN; TRABECTEDIN;

AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CANCER; CLINICAL TRIAL; COMPARTMENT MODEL; COMPUTER PROGRAM; COVARIANCE; DOSAGE SCHEDULE COMPARISON; DOSE TIME EFFECT RELATION; DRUG ACCUMULATION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG DOSE REGIMEN; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; FEMALE; HUMAN; LIVER METASTASIS; LIVER TOXICITY; MALE; META ANALYSIS; MONOTHERAPY; MULTIPLE CYCLE TREATMENT; NEUTROPENIA; POPULATION RESEARCH; PRIORITY JOURNAL; SEX DIFFERENCE; SIDE EFFECT; SIMULATION; SYSTEMATIC REVIEW; TRANSAMINITIS; TREATMENT INDICATION;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; AREA UNDER CURVE; DIOXOLES; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; MODELS, STATISTICAL; NEOPLASMS; TETRAHYDROISOQUINOLINES;

EID: 34548837518     PISSN: 03125963     EISSN: 03125963     Source Type: Journal    
DOI: 10.2165/00003088-200746100-00005     Document Type: Article

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