A phase II study of Yondelis® (trabectedin, ET-743) as a 24-h continuous intravenous infusion in pretreated advanced breast cancer

British Journal of Cancer

Volumn 94, Issue 11, 2006, Pages 1610-1614

  Zelek, L ^a,b   Yovine, A ^c   Brain, E ^d   Turpin, F ^d   Taamma, A ^e   Riofrio, M ^a   Spielmann, M ^a   Jimeno, J ^f   Misset, J L ^c  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b HENRI MONDOR HOSPITAL   (France)

^c HÔPITAL PAUL BROUSSE   (France)

^d CENTRE RENÉ HUGUENIN   (France)

^e Cvitkovic et Associes Consultants   (France)

^f PHARMAMAR S A   (Spain)

Author keywords

Breast cancer; Trabectedin; Yondelis

Indexed keywords

ANTHRACYCLINE DERIVATIVE; TAXANE DERIVATIVE; TRABECTEDIN;

ABNORMALLY HIGH SUBSTRATE CONCENTRATION IN BLOOD; ADULT; ADVANCED CANCER; AGED; ALKALINE PHOSPHATASE BLOOD LEVEL; ANEMIA; AREA UNDER THE CURVE; ARTICLE; ASCIDIACEA; ASTHENIA; BILIRUBIN BLOOD LEVEL; BREAST CANCER; CANCER COMBINATION CHEMOTHERAPY; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG DOSE REDUCTION; DRUG HALF LIFE; ECTEINASCIDIA TURBINATA; FATIGUE; FEASIBILITY STUDY; FEBRILE NEUTROPENIA; FEMALE; GASTROINTESTINAL TOXICITY; HUMAN; LIVER TOXICITY; MUCOSA INFLAMMATION; NAUSEA; NEUTROPENIA; OVARY CANCER; PHASE 2 CLINICAL TRIAL; PLASMA CLEARANCE; PRIORITY JOURNAL; PROSTATE CANCER; SARCOMA; THROMBOCYTOPENIA; VOMITING;

ADULT; AGED; ANTINEOPLASTIC AGENTS, ALKYLATING; BREAST NEOPLASMS; DIOXOLES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; ISOQUINOLINES; LIVER NEOPLASMS; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM STAGING; TETRAHYDROISOQUINOLINES;

EID: 33745259879     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6603142     Document Type: Article

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