Arene cis-dihydrodiols: Useful precursors for the preparation of analogues of the anti-tumour agent, 2-crotonyloxymethyl-(4R,5R,6R)-4,5,6-trihydroxycyclohex-2-enone (COTC)

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 21, 2007, Pages 5974-5977

  Arthurs, Claire L ^a   Raftery, James ^a   Whitby, Helen L ^a   Whitehead, Roger C ^a   Wind, Natasha S ^a   Stratford, Ian J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Anti tumour; COTC; Glutathione; Glutathione transferase

Indexed keywords

2 CROTONYLOXYMETHYL 4,5,6 TRIHYDROXY 2 CYCLOHEXENONE; 2 CROTONYLOXYMETHYLCYCLOHEX 2 ENONE; ANTINEOPLASTIC AGENT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL;

ANTINEOPLASTIC AGENTS; CRYSTALLOGRAPHY, X-RAY; CYCLOHEXANONES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR;

STREPTOMYCES;

EID: 34548822439     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.07.070     Document Type: Article

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