Molecular basis of the antitumor activities of 2-crotonyloxymethyl-2-cycloalkenones

Journal of Medicinal Chemistry

Volumn 46, Issue 1, 2003, Pages 194-196

  Joseph, Erin ^a   Eiseman, Julie L ^a   Hamilton, Diana S ^b   Wang, Haibo ^b   Tak, Heekyung ^b   Ding, Zhebo ^c   Ganem, Bruce ^c   Creighton, Donald J ^b  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^c Department of Molecular Biology and Genetics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 CROTONYLOXYMETHYL 2 CYCLOALKENONE; ANTINEOPLASTIC AGENT; GLUTATHIONE; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL LEVEL; CONJUGATE; CONJUGATION; CONTROLLED STUDY; IC 50; IN VITRO STUDY; MELANOMA; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; TUMOR CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; CROTONIC ACIDS; CYCLOHEXANES; CYCLOHEXANONES; CYCLOPARAFFINS; GLUTATHIONE; MICE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0037413532     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0203027     Document Type: Article

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