Benzodiazepines Impair the Acquisition and Reversal of Olfactory Go/No-Go Discriminations in Rats

Behavioral Neuroscience

Volumn 121, Issue 3, 2007, Pages 527-534

  Sokolic, Ljiljana ^a   McGregor, Iain S ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

auditory; benzodiazepine; olfactory; rat; successive discrimination

Indexed keywords

MIDAZOLAM;

ANALYTICAL ERROR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUDITORY DISCRIMINATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; EXPERIMENTAL STUDY; FEMALE; LEARNING; MENTAL PERFORMANCE; NONHUMAN; OLFACTORY BULB; OLFACTORY DISCRIMINATION; OUTCOME ASSESSMENT; RAT; STATISTICAL ANALYSIS; TREATMENT RESPONSE;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BENZODIAZEPINES; CHOICE BEHAVIOR; DIAZEPAM; DISCRIMINATION (PSYCHOLOGY); DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GABA MODULATORS; MIDAZOLAM; OLFACTION DISORDERS; RATS; RATS, WISTAR; REVERSAL LEARNING;

EID: 34548818545     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/0735-7044.121.3.527     Document Type: Article

References (39)

1. Ashton H. The diagnosis and management of benzodiazepine dependence. Current Opinion in Psychiatry 18 (2005) 249-255
2. Australian Code of Practice for the Care and Use of Animals for Scientific Purposes. 7th ed. (2004), Australian Government, Canberra, Australia
3. Beracochea D. Anterograde and retrograde effects of benzodiazepines on memory. ScientificWorldJournal 6 (2006) 1460-1465
4. Bindra D., and Reichert H. The nature of dissociation: Effects of transitions between normal and barbiturate-induced states on reversal learning and habituation. Psychopharmacologia 10 (1967) 330-344
5. Calu D.J., Roesch M.R., Stalnaker T.A., and Schoenbaum G. Associative encoding in posterior piriform cortex during odor discrimination and reversal learning. Cerebral Cortex (2006) Advance online publication
6. Caul W.F. Effects of amobarbital on discrimination acquisition and reversal. Psychopharmacologia 11 (1967) 414-421
7. Cole S.O. Diazepam-induced impairment of a go-no go successive discrimination. Behavioral Neural Biology 53 (1990) 371-377
8. Curran H.V. Benzodiazepines, memory and mood: A review. Psychopharmacology (Berl) 105 (1991) 1-8
9. Dielenberg R.A., Arnold J.C., and McGregor I.S. Low-dose midazolam attenuates predatory odor avoidance in rats. Pharmacology, Biochemistry & Behavior 62 (1999) 197-201
10. Fillmore M.T., Kelly T.H., Rush C.R., and Hays L. Retrograde facilitation of memory by triazolam: Effects on automatic processes. Psychopharmacology (Berl) 158 (2001) 314-321
11. Fritschy J.M., and Mohler H. GABA-A-receptor heterogeneity in the adult rat brain: Differential regional and cellular distribution of seven major subunits. Journal of Comparative Neurology 359 (1995) 154-194
12. Galizio M., Miller L., Ferguson A., McKinney P., and Pitts R.C. Olfactory repeated discrimination reversal in rats: Effects of chlordiazepoxide, dizocilpine, and morphine. Behavioral Neuroscience 120 (2006) 1175-1179
13. Gray J.A., and McNaughton N. The neuropsychology of anxiety: An enquiry into the functions of the septo-hippocampal system. 2nd ed. 33 (2003), Oxford University Press, New York
14. Haberly L.B. Parallel-distributed processing in olfactory cortex: New insights from morphological and physiological analysis of neuronal circuitry. Chemical Senses 26 (2001) 551-576
15. Iwahara S., and Sugimura T. [Effects of chlordiazepoxide on black-white discrimination acquisition and reversal in rats]. Shinrigaku Kenkyu 41 (1970) 142-150
16. Lader M., and Petursson H. Long-term effects of benzodiazepines. Neuropharmacology 22 (1983) 527-533
17. Laurie D.J., Seeburg P.H., and Wisden W. The distribution of 13 GABAA receptor subunit mRNAs in the rat brain: II. Olfactory bulb and cerebellum. Journal of Neuroscience 12 (1992) 1063-1076
18. McGregor I.S. Using Strawberry Tree Workbench Mac and Workbench PC Software for data acquisition and control in the animal learning laboratory. Behavioural Research Methods, Instruments & Computers 28 (1996) 38-48
19. McGregor I.S., Hargreaves G.A., Apfelbach R., and Hunt G.E. Neural correlates of cat odor-induced anxiety in rats: Region-specific effects of the benzodiazepine midazolam. Journal of Neuroscience 24 (2004) 4134-4144
20. McNaughton N. Chlordiazepoxide and successive discrimination: Different effects on acquisition and performance. Pharmacology, Biochemistry & Behavior 23 (1985) 487-494
21. Mouly A.M., and Di Scala G. Entorhinal cortex stimulation modulates amygdala and piriform cortex responses to olfactory bulb inputs in the rat. Neuroscience 137 (2006) 1131-1141
22. Nigrosh B.J., Slotnick B.M., and Nevin J.A. Olfactory discrimination, reversal learning, and stimulus control in rats. Journal of Comparative Physiology & Psychology 89 (1975) 285-294
23. Obradovic D.I., Savic M.M., Andjelkovic D.S., Ugresic N.D., and Bokonjic D.R. The influence of midazolam on active avoidance retrieval and acquisition rate in rats. Pharmacology, Biochemistry & Behavior 77 (2004) 77-83
24. Otto T., Schottler F., Staubli U., Eichenbaum H., and Lynch G. Hippocampus and olfactory discrimination learning: Effects of entorhinal cortex lesions on olfactory learning and memory in a successive-cue, go-no-go task. Behavioral Neuroscience 105 (1991) 111-119
25. Rodrigo E.K., and Williams P. Frequency of self-reported "anxiolytic withdrawal" symptoms in a group of female students experiencing anxiety. Psychological Medicine 16 (1986) 467-472
26. Roesch M.R., Stalnaker T.A., and Schoenbaum G. Associative encoding in anterior piriform cortex versus orbitofrontal cortex during odor discrimination and reversal learning. Cerebral Cortex (2006) Advance online publication
27. Rolls E.T., Critchley H.D., Mason R., and Wakeman E.A. Orbitofrontal cortex neurons: Role in olfactory and visual association learning. Journal of Neurophysiology 75 (1996) 1970-1981
28. Salcedo E., Zhang C., Kronberg E., and Restrepo D. Analysis of training-induced changes in ethyl acetate odor maps using a new computational tool to map the glomerular layer of the olfactory bulb. Chemical Senses 30 (2005) 615-626
29. Savic M.M., Obradovic D.I., Ugresic N.D., and Bokonjic D.R. Memory effects of benzodiazepines: Memory stages and types versus binding-site subtypes. Neural Plasticity 12 (2005) 289-298
30. Schoenbaum G., Chiba A.A., and Gallagher M. Neural encoding in orbitofrontal cortex and basolateral amygdala during olfactory discrimination learning. Journal of Neuroscience 19 (1999) 1876-1884
31. Schwabe K., Ebert U., and Loscher W. The central piriform cortex: Anatomical connections and anticonvulsant effect of GABA elevation in the kindling model. Neuroscience 126 (2004) 727-741
32. Slotnick B.M. Animal cognition and the rat olfactory system. Trends in Cognitive Sciences 5 (2001) 216-222
33. Slotnick B.M., and Schellinck H. Methods in olfactory research with rodents. In: Simon S.A., and Nicolelis M. (Eds). Frontiers and methods in chemosenses (2001), CRC Press, Washington, D.C. 21-61
34. Slotnick B.M., and Schoonover F.W. Olfactory pathways and the sense of smell. Neuroscience and Biobehavioral Reviews 16 (1992) 453-472
35. Sokolic L., Laing D.G., and McGregor I.S. Asymmetric suppression of aliphatic aldehydes in binary mixtures: Behavioural studies in the laboratory rat. Chemical Senses 32 (2007) 191-199
36. Thiebot M.H. Some evidence for amnesic-like effects of benzodiazepines in animals. Neuroscience & Biobehavioral Reviews 9 (1985) 95-100
37. Tyrer P., Owen R., and Dawling S. Gradual withdrawal of diazepam after long-term therapy. Lancet 1 (1983) 1402-1406
38. Vachon L., Kitsikis A., and Roberge A.G. Chlordiazepoxide, go-nogo successive discrimination and brain biogenic amines in cats. Pharmacology, Biochemistry & Behavior 20 (1984) 9-22
39. Wisden W., Laurie D.J., Monyer H., and Seeburg P.H. The distribution of 13 GABA-A receptor subunit mRNAs in the rat brain: I. Telencephalon, diencephalon, mesencephalon. Journal of Neuroscience 12 (1992) 1040-1062