Analysis of training-induced changes in ethyl acetate odor maps using a new computational tool map the Glomerular layer of the olfactory bulb

Chemical Senses

Volumn 30, Issue 7, 2005, Pages 615-626

  Salcedo, Ernesto ^a   Zhang, Chunbo ^b   Kronberg, Eugene ^a   Restrepo, Diego ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b ILLINOIS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

c fos; Glomerulus; Go no go operant conditioning; Neuroinformatics; Odor map; Olfactory bulb

Indexed keywords

ACETIC ACID ETHYL ESTER; PROTEIN C FOS;

ANIMAL EXPERIMENT; ARTICLE; COMPUTER MODEL; COMPUTER PROGRAM; DATA ANALYSIS; INSTRUMENTAL CONDITIONING; MOUSE; NERVE FIBER; NONHUMAN; ODOR; OLFACTORY BULB; OLFACTORY DISCRIMINATION; OLFACTORY RECEPTOR; PRIORITY JOURNAL; SENSORY NERVE CELL; SENSORY STIMULATION; STATISTICAL ANALYSIS; TRAINING; UPREGULATION;

ACETATES; ANIMALS; BRAIN MAPPING; CONDITIONING (PSYCHOLOGY); DISCRIMINATION (PSYCHOLOGY); IN SITU HYBRIDIZATION; MICE; MICE, INBRED STRAINS; ODORS; OLFACTORY BULB; PROTO-ONCOGENE PROTEINS C-FOS; RNA, MESSENGER; SOFTWARE; STIMULATION, CHEMICAL; UP-REGULATION;

EID: 24944518569     PISSN: 0379864X     EISSN: None     Source Type: Journal    
DOI: 10.1093/chemse/bji055     Document Type: Article

References (42)

1. Bodyak, N. and Slotnick, B. (1999) Performance of mice in an automated olfactometer: Odor detection, discrimination and odor memory. Chem. Senses, 24, 637-645.
2. Buck, L.B. (2000) The molecular architecture of odor and pheromone sensing in mammals. Cell, 100, 611-618.
3. Curran-Everett, D. (2000) Multiple comparisons: Philosophies and illustrations. Am. J. Physiol. Regul. Integr. Comp. Physiol., 279, R1-R8.
4. Franklin, K.B.J. and Paxinos, G. (1997) The Mouse Brain in Stereotaxic Coordinates. Academic Press, San Diego, CA.
5. Friedrich, R.W. and Korsching, S.I. (1998) Chemotopic, combinatorial, and noncombinatorial odorant representations in the olfactory bulb revealed using a voltage-sensitive axon tracer. J. Neurosci., 18, 9977-9988.
6. Guthrie, K.M., Anderson, A.J., Leon, M. and Gall, C. (1993) Odor-induced increases in c-fos mRNA expression reveal an anatomical "unit" for odor processing in olfactory bulb. Proc. Natl Acad. Sci. USA, 90, 3329-3333.
7. Inaki, K., Takahashi, Y.K., Nagayama, S. and Mori, K. (2002) Molecular-feature domains with posterodorsal-anteroventral polarity in the symmetrical sensory maps of the mouse olfactory bulb: Mapping of odourant-induced Zif268 expression. Eur. J. Neurosci., 15, 1563-1574.
8. Johnson, B.A. and Leon, M. (1996) Spatial distribution of [14C]2-deoxyglucose uptake in the glomerular layer of the rat olfactory bulb following early odor preference learning. J. Comp. Neurol., 376, 557-566.
9. Johnson, B.A. and Leon, M. (2000a) Modular representations of odorants in the glomerular layer of the rat olfactory bulb and the effects of stimulus concentration. J. Comp. Neurol., 422, 496-509.
10. Johnson, B.A. and Leon, M. (2000b) Odorant molecular length: One aspect of the olfactory code. J. Comp. Neurol., 426, 330-338.
11. Johnson, B.A., Woo, C.C., Duong, H., Nguyen, V. and Leon, M. (1995) A learned odor evokes an enhanced Fos-like glomerular response in the olfactory bulb of young rats. Brain Res., 699, 192-200.
12. Johnson, B.A., Woo, C.C., Hingco, E.E., Pham, K.L. and Leon, M. (1999) Multidimensional chemotopic responses to n-aliphatic acid odorants in the rat olfactory bulb. J. Comp. Neurol., 409, 529-548.
13. Lin, W., Arellano, J., Slotnick, B. and Restrepo, D. (2004) Odors detected by mice deficient in cyclic nucleotide-gated channel subunit A2 stimulate the main olfactory system. J. Neurosci., 24, 3703-3710.
14. Lin, W., Margolskee, R.F., Zhao, Z., Liman, E.R. and Restrepo, D. (2005) Expression of TRPM5 in the main olfactory epithelium [abstract]. Chem. Senses, 30, A127.
15. Liu, N., Xu, F., Marenco, L., Hyder, F., Miller, P. and Shepherd, G.M. (2004) Informatics approaches to functional MRI odor mapping of the rodent olfactory bulb: OdorMapBuilder and OdorMapDB Neuroinformatics, 2, 3-18.
16. Mombaerts, P., Wang, F., Dulac, C., Chao, S.K., Nemes, A., Mendelsohn, M., Edmondson, J. and Axel, R. (1996) Visualizing an olfactory sensory map. Cell, 87, 675-686.
17. Montag-Sallaz, M. and Buonviso, N. (2002) Altered odor-induced expression of c-fos and arg 3.1 immediate early genes in the olfactory system after familiarization with an odor. J. Neurobiol., 52, 61-72.
18. Munger, S.D., Lane, A.P., Zhong, H., Leinders-Zufall, T., Yau, K.-W., Zufall, F. and Reed, R.R. (2001) Central role of the CNGA4 channel subunit in Ca2+-calmodulin-dependent odor adaptation. Science, 294, 2172-2175.
19. Nagao, H., Yoshihara, Y., Mitsui, S., Fujisawa, H. and Mori, K. (2000) Two mirror-image sensory maps with domain organization in the mouse main olfactory bulb. Neuroreport, 11, 3023-3027.
20. Ressler, K.J., Sullivan, S.L. and Buck, L.B. (1994) Information coding in the olfactory system: Evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Cell, 79, 1245-1255.
21. Royet, J.P., Sicard, G., Souchier, C. and Jourdan, F. (1987) Specificity of spatial patterns of glomerular activation in the mouse olfactory bulb: Computer-assisted image analysis of 2-deoxyglucose autoradiograms. Brain Res., 417, 1-11.
22. Rubin, B.D. and Katz, L.C. (1999) Optical imaging of odorant representations in the mammalian olfactory bulb. Neuron, 23, 499-511.
23. Sallaz, M. and Jourdan, F. (1993) C-fos expression and 2-deoxyglucose uptake in the olfactory bulb of odour-stimulated awake rats. Neuroreport, 4, 55-58.
24. Schaefer, M.L., Finger, T.E. and Restrepo, D. (2001a) Variability of position of the P2 glomerulus within a map of the mouse olfactory bulb. J. Comp. Neurol., 436, 351-362.
25. Schaefer, M.L., Young, D.A. and Restrepo, D. (2001b) Olfactory fingerprints for major histocompatibility complex-determined body odors. J. Neurosci., 21, 2481-2487.
26. Schoppa, N.E., Kinzie, J.M., Sahara, Y., Segerson, T.P. and Westbrook, G.L. (1998) Dendrodendritic inhibition in the olfactory bulb is driven by NMDA receptors. J. Neurosci., 18, 6790-6802.
27. Sharp, F.R., Kauer, J.S. and Shepherd, G.M. (1977) Laminar analysis of 2-deoxyglucose uptake in olfactory bulb and olfactory cortex of rabbit and rat. J. Neurophysiol., 40, 800-813.
28. Shepherd, G.M., Chen, W.R. and Greer, C.A. (2004) Olfactory bulb. In Shepherd, G.M. (ed.), The Synaptic Organization of the Brain. Oxford University Press, New York, pp. 159-204.
29. Slotnick, B. and Bodyak, N. (2002) Odor discrimination and odor quality perception in rats with disruption of connections between the olfactory epithelium and olfactory bulbs. J. Neurosci., 22, 4205-4216.
30. Strotmann, J., Conzelmann, S., Beck, A., Feinstein, P., Breer, H. and Mombaerts, P. (2000) Local permutations in the glomerular array of the mouse olfactory bulb. J. Neurosci., 20, 6927-6938.
31. Uchida, N., Takahashi, Y.K., Tanifuji, M. and Mori, K. (2000) Odor maps in the mammalian olfactory bulb: Domain organization and odorant structural features. Nat. Neurosci., 3, 1035-1043.
32. Vassar, R., Ngai, J. and Axel, R. (1993) Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium. Cell, 74, 309-318.
33. Vedin, V., Slotnick, B. and Berghard, A. (2004) Zonal ablation of the olfactory sensory neuroepithelium of the mouse: Effects on odorant detection. Eur. J. Neurosci., 20, 1858-1864.
34. Wachowiak, M. and Cohen, L.B. (2001) Representation of odorants by receptor neuron input to the mouse olfactory bulb. Neuron, 32, 723-735.
35. Watt, W.C., Sakano, H., Lee, Z.Y., Reusch, J.E., Trinh, K. and Storm, D.R. (2004) Odorant stimulation enhances survival of olfactory sensory neurons via MAPK and CREB. Neuron, 41, 955-967.
36. Wilson, D.A., Sullivan, R.M., Gall, C.M. and Guthrie, K.M. (1996) NMDA-receptor modulation of lateral inhibition and c-fos expression in olfactory bulb. Brain Res., 719, 62-71.
37. Woodley, S.K., Cloe, A.L., Waters, P. and Baum, M.J. (2004) Effects of vomeronasal organ removal on olfactory sex discrimination and odor preferences of female ferrets. Chem. Senses, 29, 659-669.
38. Xu, F., Greer, C.A. and Shepherd, G.M. (2000a) Odor maps in the olfactory bulb. J. Comp. Neurol., 422, 489-495.
39. Xu, F., Kida, I., Hyder, F. and Shulman, R.G. (2000b) Assessment and discrimination of odor stimuli in rat olfactory bulb by dynamic functional MRI. Proc. Natl Acad. Sci. USA, 97, 10601-10606.
40. Xu, F., Liu, N., Kida, I., Rothman, D.L., Hyder, F. and Shepherd, G.M. (2003) Odor maps of aldehydes and esters revealed by functional MRI in the glomerular layer of the mouse olfactory bulb Proc. Natl. Acad. Sci. USA, 100, 11029-11034.
41. Xu, F., Schaefer, M., Kida, I., Schafer, J., Liu, N., Rothman, D.L., Hyder, F., Restrepo, D. and Shepherd, G.M. (2005) Simultaneous activation of mouse main and accessory olfactory bulbs by odors or pheromones. J. Comp. Neurol., 489, 491-500.
42. Zheng, C., Feinstein, P., Bozza, T., Rodriguez, I. and Mombaerts, P. (2000) Peripheral olfactory projections are differentially affected in mice deficient in a cyclic nucleotide-gated channel subunit. Neuron, 26, 81-91.