Engineering a monomeric miniature protein

Journal of the American Chemical Society

Volumn 129, Issue 36, 2007, Pages 11024-11025

  Hodges, Abby M ^a   Schepartz, Alanna ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; PANCREAS POLYPEPTIDE; PEPTIDE YY; PROLINE;

ARTICLE; CIRCULAR DICHROISM; DIMERIZATION; DNA BINDING; NUCLEAR MAGNETIC RESONANCE; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PANCREATIC POLYPEPTIDE; PROTEIN ENGINEERING;

EID: 34548810336     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja074859t     Document Type: Article

References (29)

1. Zondlo, N. J.; Schepartz, A. J. Am. Chem. Soc. 1999, 121, 6938-6939.
2. Chin, J. W.; Schepartz, A. J. Am. Chem. Soc. 2001, 123, 2929-2930.
3. Montclare, J. K.; Schepartz, A. J. Am. Chem. Soc. 2003, 125, 3416-3417.
4. Yang, L.; Schepartz. A. Biochemistry 2005, 44, 7469-7478.
5. Chin, J. W.; Schepartz, A. Angew. Chem., Int. Ed. Engl. 2001, 40, 3806-3809.
6. Rutledge, S. E.; Volkman, H. M.; Schepartz, A. J. Am. Chem. Soc. 2003, 125, 14336-14347.
7. Golemi-Kotra, D.; Mahaffy, R.; Footer, M. J.; Holtzman, J. H.; Pollard, T. D.; Theriot, J. A.; Schepartz, A. J. Am. Chem. Soc. 2004, 126, 4-5.
8. Shimba, N.; Nomura, A. M.; Marnett, A. B.; Craik, C. S. J. Virology 2004, 78, 6657-6665.
9. Cobos, E. S.; Pisabarro, M. T.; Vega, M. C.; Lacroix, E.; Serrano, L.; Ruiz-Sanz, J.; Martinez, J. C. J. Mol. Biol. 2004, 342, 355-365.
10. Volkman, H. M.; Rutledge, S. E.; Schepartz, A. J. Am. Chem. Soc. 2005, 127, 4649-4658.
11. Schneider, T. L.; Mathew, R. S.; Rice, K. P.; Tamaki, K.; Wood, J. L.; Schepartz, A. Org. Lett. 2005, 7, 1695-1698.
12. Gemperli, A. C.; Rutledge, S. E.; Maranda, A.; Schepartz, A. J. Am. Chem. Soc. 2005, 127, 1596-1597.
13. Zellefrow, C. D.; Griffiths, J. S.; Saha, S.; Hodges. A. M.; Goodman, J. L.; Paulk, J.; Kritzer, J. A.; Schepartz, A. J. Am. Chem. Soc. 2006, 128, 16506-16507.
14. Kritzer, J. A.; Zutshi, R.; Cheah, M.; Ran, F. A.; Webman, R.; Wongjirad, T. M.; Schepartz, A. Chembiochem 2006, 7, 29-31.
15. Noelken, M. E.; Chang, P. J.; Kimmel, J. R. Biochemistry 1980, 19, 1838-1843.
16. Chang, P. J.; Noelken, M. E.; Kimmel, J. R. Biochemistry 1980, 19, 1844-1849.
17. Taylor, S. E.; Rutherford, T. J.; Allemann, R. K. Bioorg. Med. Chem. Lett. 2001, 11, 2631-2635.
18. Nicoll, A. J.; Allemann, R. K. Org. Biomol. Chem. 2004, 2, 2175-2180.
19. Jurt, S.: Aemissegger, A.; Guntert, P.; Zerbe, O.; Hilvert, D. Angew. Chem. 2006, 118, 6445-6448.
20. Blundell, T. L.; Pitts, J. E.; Tickle, I. J.; Wood, S. P.; Wu, C. W. Proc. Natl. Acad. Sci. U.S.A. 1981, 78, 4175-4179.
21. Keire, D. A.; Mannon, P.; Kobayashi, M.; Walsh, J. H.; Solomon, T. E.; Reeve, J. R. Am. J. Physiol. 2000, 279, G126-G131.
22. Keire, D. A.; Kobayashi, M.; Solomon, T. E.; Reeve, J. R. Biochemistry 2000, 39, 9935-9942.
23. Lerch, M.; Mayrhofer, M.; Zerbe, O. J. Mol. Biol. 2004, 339, 1153-1168.
24. Bader, R.; Zerbe, O. Chembiochem 2005, 6, 1520-1534.
25. Nygaard, R.; Nielbo, S.; Schwartz, T. W.; Poulsen, F. M. Biochemistry 2006, 45, 8350-8357.
26. Previous work has shown that Y20 contributes to monomer and/or dimer stability of the related protein bPP. Woll, M. G.; Gellman, S. H. J. Am. Chem. Soc. 2004, 126, 11172-11174.
27. Bjornholm, B.; Jorgensen, F. S.; Schwartz, T. W. Biochemistry 1993, 32, 2954-2959.
28. Neumoin, A.; Mares, J.; Lerch-Bader, M.; Bader, R.; Zerbe, O. J. Am. Chem. Soc. 2007, 129, 8811-8817.
29. Please see Supporting Information for details.