Effect of photosensitizer dose on fluence rate responses to photodynamic therapy

Photochemistry and Photobiology

Volumn 83, Issue 5, 2007, Pages 1040-1048

  Wang, Hsing Wen ^a   Rickter, Elizabeth ^a   Yuan, Min ^a   Wileyto, E Paul ^a   Glatstein, Eli ^a   Yodh, Arjun ^a   Busch, Theresa M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; OXYGEN; PHOTOSENSITIZING AGENT;

ANIMAL; C3H MOUSE; CONFERENCE PAPER; DOSE RESPONSE; METABOLISM; MOUSE; PHOTOCHEMOTHERAPY;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEMOGLOBINS; MICE; MICE, INBRED C3H; OXYGEN; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS;

EID: 34548803059     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-1097.2007.00139.x     Document Type: Conference Paper

References (41)

1. Henderson, B. W., T. M. Busch J. W. Snyder (2006) Fluence rate as a modulator of PDT mechanisms. Lasers Surg. Med. 38, 489 493.
2. Sitnik, T. M., J. A. Hampton B. W. Henderson (1998) Reduction of tumour oxygenation during and after photodynamic therapy in vivo: Effects of fluence rate. Br. J Cancer. 77, 1386 1394.
3. Henderson, B. W., S. O. Gollnick, J. W. Snyder, T. M. Busch, P. C. Kousis, R. T. Cheney J. Morgan (2004) Choice of oxygen-conserving treatment regimen determines the inflammatory response and outcome of photodynamic therapy of tumors. Cancer Res. 64, 2120 2126.
4. Coutier, S., L. N. Bezdetnaya, T. H. Foster, R. M. Parache F. Guillemin (2002) Effect of irradiation fluence rate on the efficacy of photodynamic therapy and tumor oxygenation in meta-tetra (hydroxyphenyl) chlorin (mTHPC)-sensitized HT29 xenografts in nude mice. Radiat. Res. 158, 339 345.
5. Angell-Petersen, E., S. Spetalen, S. J. Madsen, C. H. Sun, Q. Peng, S. W. Carper, M. Sioud H. Hirschberg (2006) Influence of light fluence rate on the effects of photodynamic therapy in an orthotopic rat glioma model. J. Neurosurg. 104, 109 117.
6. Sitnik, T. M. B. W. Henderson (1998) The effect of fluence rate on tumor and normal tissue responses to photodynamic therapy. Photochem. Photobiol. 67, 462 466.
7. Ericson, M. B., C. Sandberg, B. Stenquist, F. Gudmundson, M. Karlsson, A. M. Ros, A. Rosen, O. Larko, A. M. Wennberg I. Rosdahl (2004) Photodynamic therapy of actinic keratosis at varying fluence rates: Assessment of photobleaching, pain and primary clinical outcome. Br. J. Dermatol. 151, 1204 1212.
8. Foster, T. H., R. S. Murant, R. G. Bryant, R. S. Knox, S. L. Gibson R. Hilf (1991) Oxygen consumption and diffusion effects in photodynamic therapy. Radiat. Res. 126, 296 303.
9. Henning, J. P., R. L. Fournier J. A. Hampton (1995) A transient mathematical model of oxygen depletion during photodynamic therapy. Radiat. Res. 142, 221 226.
10. Pogue, B. W. T. Hasan (1997) A theoretical study of light fractionation and dose-rate effects in photodynamic therapy. Radiat. Res. 147, 551 559.
11. Foster, T. H. L. Gao (1992) Dosimetry in photodynamic therapy: Oxygen and the critical importance of capillary density. Radiat. Res. 130, 379 383.
12. Busch, T. M., E. P. Wileyto, M. J. Emanuele, F. Del Piero, L. Marconato, E. Glatstein C. J. Koch (2002) Photodynamic therapy creates fluence rate-dependent gradients in the intratumoral spatial distribution of oxygen. Cancer Res. 62, 7273 7279.
13. Iinuma, S., K. T. Schomacker, G. Wagnieres, M. Rajadhyaksha, M. Bamberg, T. Momma T. Hasan (1999) In vivo fluence rate and fractionation effects on tumor response and photobleaching: Photodynamic therapy with two photosensitizers in an orthotopic rat tumor model. Cancer Res. 59, 6164 6170.
14. Georgakoudi, I., M. G. Nichols T. H. Foster (1997) The mechanism of Photofrin photobleaching and its consequences for photodynamic dosimetry. Photochem. Photobiol. 65, 135 144.
15. Yuan, J., P. A. Mahama-Relue, R. L. Fournier J. A. Hampton (1997) Predictions of mathematical models of tissue oxygenation and generation of singlet oxygen during photodynamic therapy. Radiat. Res. 148, 386 394.
16. Busch, T. M., S. M. Hahn, E. P. Wileyto, C. J. Koch, D. L. Fraker, P. Zhang, M. Putt, K. Gleason, D. B. Shin, M. J. Emanuele, K. Jenkins, E. Glatstein S. M. Evans (2004) Hypoxia and Photofrin uptake in the intraperitoneal carcinomatosis and sarcomatosis of photodynamic therapy patients. Clin. Cancer Res. 10, 4630 4638.
17. Wang, H. W., M. E. Putt, M. J. Emanuele, D. B. Shin, E. Glatstein, A. G. Yodh T. M. Busch (2004) Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome. Cancer Res. 64, 7553 7561.
18. Wang, H. W., T. C. Zhu, M. E. Putt, M. Solonenko, J. Metz, A. Dimofte, J. Miles, D. L. Fraker, E. Glatstein, S. M. Hahn A. G. Yodh (2005) Broadband reflectance measurements of light penetration, blood oxygenation, hemoglobin concentration, and drug concentration in human intraperitoneal tissues before and after photodynamic therapy. J. Biomed. Opt. 10, 14004.
19. Solonenko, M., R. Cheung, T. M. Busch, A. Kachur, G. M. Griffin, T. Vulcan, T. C. Zhu, H. W. Wang, S. M. Hahn A. G. Yodh (2002) In vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys and prostates. Phys. Med. Biol. 47, 857 873.
20. Menon, C., G. M. Polin, I. Prabakaran, A. Hsi, C. Cheung, J. P. Culver, J. F. Pingpank, C. S. Sehgal, A. G. Yodh, D. G. Buerk D. L. Fraker (2003) An integrated approach to measuring tumor oxygen status using human melanoma xenografts as a model. Cancer Res. 63, 7232 7240.
21. Wang, H.-W., T. Zhu, M. Solonenko, S. M. Hahn, J. M. Metz, A. Dimofte, J. Miles A. G. Yodh (2003) In-vivo measurements of penetration depth, oxygenation, and drug concentration using broadband absorption spectroscopy in human tissues before and after photodynamic therapy. Proc. SPIE 4952, 68 75.
22. Prahl, S. (2005) Optical properties spectra. Available at : http://omlc.ogi.edu/spectra/index.html. Accessed on 15 December 2005.
23. Haskell, R. C., L. O. Svaasand, T. T. Tsay, T. C. Feng, M. S. McAdams B. J. Tromberg (1994) Boundary conditions for the diffusion equation in radiative transfer. J. Opt. Soc. Am. A Opt. Image Sci. Vis. 11, 2727 2741.
24. Kienle, A. M. S. Patterson (1997) Improved solutions of the steady-state and the time-resolved diffusion equations for reflectance from a semi-infinite turbid medium. J. Opt. Soc. Am. A Opt. Image Sci. Vis. 14, 246 254.
25. Hull, E. L., M. G. Nichols T. H. Foster (1998a) Quantitative broadband near-infrared spectroscopy of tissue-simulating phantoms containing erythrocytes. Phys. Med. Biol. 43, 3381 3404.
26. Hull, E. L., M. G. Nichols T. H. Foster (1998b) Localization of luminescent inhomogeneities in turbid media with spatially resolved measurements of CW diffuse luminescence emittance. Appl. Opt. 37, 2755 2765.
27. Choe, R., T. Durduran, G. Yu, M. J. Nijland, B. Chance, A. G. Yodh N. Ramanujam (2003) Transabdominal near infrared oximetry of hypoxic stress in fetal sheep brain in utero. Proc. Natl Acad. Sci. USA 100, 12950 12954.
28. Culver, J. P., T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg A. G. Yodh (2003) Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia. J. Cereb. Blood Flow 23, 911 924.
29. Durduran, T., R. Choe, J. P. Culver, L. Zubkov, M. J. Holboke, J. Giammarco, B. Chance A. G. Yodh (2002) Bulk optical properties of healthy female breast tissue. Phys. Med. Biol. 47, 2847 2861.
30. Corlu, A., T. Durduran, R. Choe, M. Schweiger, E. M. Hillman, S. R. Arridge A. G. Yodh (2003) Uniqueness and wavelength optimization in continuous-wave multispectral diffuse optical tomography. Opt Lett. 28, 2339 2341.
31. Henderson, B. W., T. M. Busch, L. A. Vaughan, N. P. Frawley, D. Babich, T. A. Sosa, J. D. Zollo, A. S. Dee, M. T. Cooper, D. A. Bellnier, W. R. Greco A. R. Oseroff (2000) Photofrin photodynamic therapy can significantly deplete or preserve oxygenation in human basal cell carcinomas during treatment, depending on fluence rate. Cancer Res. 60, 525 529.
32. Yu, G., T. Durduran, C. Zhou, T. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn A. G. Yodh (2006) Real-time in situ monitoring of human prostate photodynamic therapy with diffuse light. Photochem. Photobiol. 82, 1279 1284.
33. Langmack, K., R. Mehta, P. Twyman P. Norris (2001) Topical photodynamic therapy at low fluence rates - theory and practice. J. Photochem. Photobiol. B 60, 37 43.
34. Sitnik, T. M. B. W. Henderson (1997) Effects of fluence rate on cytotoxicity during photodynamic therapy. Proc. SPIE 2972, 95 102.
35. Madsen, S. J., C. H. Sun, B. J. Tromberg, V. P. Wallace H. Hirschberg (2000) Photodynamic therapy of human glioma spheroids using 5-aminolevulinic acid. Photochem. Photobiol. 72, 128 134.
36. Seshadri, M., J. A. Spernyak, R. Mazurchuk, S. H. Camacho, A. R. Oseroff, R. T. Cheney D. A. Bellnier (2005) Tumor vascular response to photodynamic therapy and the antivascular agent 5,6-dimethylxanthenone-4-acetic acid: Implications for combination therapy. Clin. Cancer Res. 11, 4241 4250.
37. Pham, T. H., R. Hornung, M. W. Berns, Y. Tadir B. J. Tromberg (2001) Monitoring tumor response during photodynamic therapy using near-infrared photon-migration spectroscopy. Photochem. Photobiol. 73, 669 677.
38. Zhu, T. C., J. C. Finlay S. M. Hahn (2005) Determination of the distribution of light, optical properties, drug concentration, and tissue oxygenation in-vivo in human prostate during motexafin lutetium-mediated photodynamic therapy. J. Photochem. Photobiol. B 79, 231 241.
39. Cottrell, W. J., A. R. Oseroff T. H. Foster (2006a) Portable instrument that integrates irradiation with fluorescence and reflectance spectroscopies during clinical photodynamic therapy of cutaneous disease. Rev. Sci. Instrum. 77, 064302.
40. Cottrell, W. J., A. R. Oseroff T. H. Foster (2006b) System for providing simultaneous PDT delivery and dual spectroscopic monitoring in clinical basal cell carcinoma therapy. Proc. SPIE 6139, 613918-1 613918-10.
41. Weersink, R. A., A. Bogaards, M. Gertner, S. R. Davidson, K. Zhang, G. Netchev, J. Trachtenberg B. C. Wilson (2005) Techniques for delivery and monitoring of TOOKAD (WST09)-mediated photodynamic therapy of the prostate: Clinical experience and practicalities. J. Photochem. Photobiol. B 79, 211 222.