Modulation of tight junctions does not predict oral absorption of hydrophilic compounds: Use of caco-2 and calu-3 cells

Archives of Pharmacal Research

Volumn 30, Issue 8, 2007, Pages 1002-1007

  Kamath, Amrita V ^a   Morrison, Richard A ^a,b   Mathias, Neil R ^a   Dando, Sandra A ^a   Marino, Anthony M ^a   Chong, Saeho ^a  

^a BRISTOL MYERS SQUIBB   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Caco 2 cells; Calcium depletion; Calu 3 cells; Hydrophilic compound; Paracellular transport

Indexed keywords

CALCIUM; DRUG;

ABSORPTION; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CHEMISTRY; EPITHELIUM CELL; HUMAN; METABOLISM; MOUTH MUCOSA; PHYSIOLOGY; TIGHT JUNCTION;

ABSORPTION; CACO-2 CELLS; CALCIUM; CELL MEMBRANE PERMEABILITY; EPITHELIAL CELLS; HUMANS; MOUTH MUCOSA; PHARMACEUTICAL PREPARATIONS; TIGHT JUNCTIONS;

EID: 34548792977     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02993969     Document Type: Article

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