Mechanism of DNA-binding loss upon single-point mutation in p53

Journal of Biosciences

Volumn 32, Issue 1, 2007, Pages 827-839

  Wright, Jon D ^a   Lim, Carmay ^a,b  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

Free energy decomposition; Molecular dynamics simulations; p53 mutants; Protein DNA interactions

Indexed keywords

PROTEIN P53;

AMINO ACID; DNA; MUTATION; PHOSPHATE; PROTEIN;

CHROMOSOME SUBSTITUTION; CONFERENCE PAPER; DNA BINDING; METHODOLOGY; MOLECULAR MECHANICS; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN DEPLETION; PROTEIN DNA BINDING; VALIDATION PROCESS;

EID: 34548757465     PISSN: 02505991     EISSN: 02505991     Source Type: Journal    
DOI: 10.1007/s12038-007-0083-3     Document Type: Conference Paper

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