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1
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33845203842
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Efficacy and response with olopatadine versus epinastine in ocular allergic symptoms: A post hoc analysis of data from a conjunctival allergen challenge study
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Finegold I, Granet DB, D'Arienzo PA, Epstein AB. Efficacy and response with olopatadine versus epinastine in ocular allergic symptoms: a post hoc analysis of data from a conjunctival allergen challenge study. Clin Therapeut 2006; 28:1630-1638.
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(2006)
Clin Therapeut
, vol.28
, pp. 1630-1638
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Finegold, I.1
Granet, D.B.2
D'Arienzo, P.A.3
Epstein, A.B.4
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2
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33645305150
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Randomised controlled trial of topical ciclosporin A in steroid dependant allergic conjunctivitis
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Daniell M, Constantinou M, Vu HT, Taylor HR. Randomised controlled trial of topical ciclosporin A in steroid dependant allergic conjunctivitis. Br J Ophthalmol 2006; 90:461-464.
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(2006)
Br J Ophthalmol
, vol.90
, pp. 461-464
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Daniell, M.1
Constantinou, M.2
Vu, H.T.3
Taylor, H.R.4
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3
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33947594046
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Aude Pauly A, Brignole-Baudouin F, Guenoun J-M, et al. Comparative study of topical antiallergic eye drops on human conjunctiva-derived cells: responses to histamine and IFN-γ and toxicological profiles. Graefe's Arch Clin Esp Ophthalmol 2007; 245:534-546. This study found that many of the combination antihistamine/mast cell stabilizers have antiinflammatory properties.
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Aude Pauly A, Brignole-Baudouin F, Guenoun J-M, et al. Comparative study of topical antiallergic eye drops on human conjunctiva-derived cells: responses to histamine and IFN-γ and toxicological profiles. Graefe's Arch Clin Esp Ophthalmol 2007; 245:534-546. This study found that many of the combination antihistamine/mast cell stabilizers have antiinflammatory properties.
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4
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33746492214
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Cyclosporine A inhibits eosinopilic infiltration into the conjunctiva mediated by type IV allergic reactions
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Fukushima A, Yamaguchi T, Ishida W, et al. Cyclosporine A inhibits eosinopilic infiltration into the conjunctiva mediated by type IV allergic reactions. Clin Exp Ophthalmol 2006; 34:347-353.
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(2006)
Clin Exp Ophthalmol
, vol.34
, pp. 347-353
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Fukushima, A.1
Yamaguchi, T.2
Ishida, W.3
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5
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33845603160
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Fukushima A, Sumi T, Fukuda K, et al. Antibodies to T-cell Ig and mucin domain-containing proteins (Tim)-1 and -3 suppress the induction and progression of murine allergic conjunctivitis. Biochem Biophys Res Commun 2007; 353:211-216. The costimulatory molecules Tim 1 and 3 were found to modulate experimental allergic conjunctivitis in an IFN-γ-dependent manner.
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Fukushima A, Sumi T, Fukuda K, et al. Antibodies to T-cell Ig and mucin domain-containing proteins (Tim)-1 and -3 suppress the induction and progression of murine allergic conjunctivitis. Biochem Biophys Res Commun 2007; 353:211-216. The costimulatory molecules Tim 1 and 3 were found to modulate experimental allergic conjunctivitis in an IFN-γ-dependent manner.
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6
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33845246651
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Fukushima A, Sumi T, Fukuda K, et al. Interleukin 10 and transforming growth factor β contribute to the development of experimentally induced allergic conjunctivitis in mice during the effector phase. Br J Ophthalmol 2006; 90: 1535-1541. The Th2 cytokines IL-10 and TGF-β were found to potentiate certain aspects of allergic conjunctivitis.
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Fukushima A, Sumi T, Fukuda K, et al. Interleukin 10 and transforming growth factor β contribute to the development of experimentally induced allergic conjunctivitis in mice during the effector phase. Br J Ophthalmol 2006; 90: 1535-1541. The Th2 cytokines IL-10 and TGF-β were found to potentiate certain aspects of allergic conjunctivitis.
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7
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33645719082
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Fukushima A, Yamaguchi T, Ishida W, et al. Role of VLA-4 in the development of allergic conjunctivitis in mice. Molecular Vision 2006; 12:310-317. This report indicates that blockade of VCAM-1 or its ligand VLA-4 prevents the development of allergic conjunctivitis.
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Fukushima A, Yamaguchi T, Ishida W, et al. Role of VLA-4 in the development of allergic conjunctivitis in mice. Molecular Vision 2006; 12:310-317. This report indicates that blockade of VCAM-1 or its ligand VLA-4 prevents the development of allergic conjunctivitis.
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8
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34447552535
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Thymus-derived CD4+ CD25+ T cells suppress the development of murine allergic conjunctivitis
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Sumi T, Fukushima A, Fukuda K, et al. Thymus-derived CD4+ CD25+ T cells suppress the development of murine allergic conjunctivitis. Int Arch Allergy Immunol 2007; 143:276-281.
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(2007)
Int Arch Allergy Immunol
, vol.143
, pp. 276-281
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Sumi, T.1
Fukushima, A.2
Fukuda, K.3
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9
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33845747696
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Systemic Tacrolimus in the treatment of severe atopic keratoconjunctivitis
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Stumpf T, Luqmani N, Sumich P, et al. Systemic Tacrolimus in the treatment of severe atopic keratoconjunctivitis. Cornea 2006; 25:1147-1149.
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(2006)
Cornea
, vol.25
, pp. 1147-1149
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Stumpf, T.1
Luqmani, N.2
Sumich, P.3
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10
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33845399326
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Dogru M, Okada N, Asano-Kato N, et al. Alterations of the ocular surface epithelial mucins 1, 2, 4 and the tear functions in patients with atopic keratoconjunctivitis. Clin Exp Allergy 2006; 36:1556-1565.
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Dogru M, Okada N, Asano-Kato N, et al. Alterations of the ocular surface epithelial mucins 1, 2, 4 and the tear functions in patients with atopic keratoconjunctivitis. Clin Exp Allergy 2006; 36:1556-1565.
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11
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33846244951
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Measurement of inflammatory cytokines by multicytokine assay in tears of patients with glaucoma topically treated with chronic drugs
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Chronic treatment with BAC-preserved glaucoma treatments results in ocular surface inflammation. This suggests the potential benefit of using nonpreserved formulations
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Malvitte L, Montange T, Vejux A, et al. Measurement of inflammatory cytokines by multicytokine assay in tears of patients with glaucoma topically treated with chronic drugs. Br J Ophthalmol 2007; 91:29-32. Chronic treatment with BAC-preserved glaucoma treatments results in ocular surface inflammation. This suggests the potential benefit of using nonpreserved formulations.
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(2007)
Br J Ophthalmol
, vol.91
, pp. 29-32
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Malvitte, L.1
Montange, T.2
Vejux, A.3
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12
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0031406702
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Inflammatory cytokines in tears of patients with ocular rosacea
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Barton K, Monroy D, Nava A, Pflugfelder SC. Inflammatory cytokines in tears of patients with ocular rosacea. Ophthalmology 1997; 104:1868-1874.
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(1997)
Ophthalmology
, vol.104
, pp. 1868-1874
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Barton, K.1
Monroy, D.2
Nava, A.3
Pflugfelder, S.C.4
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13
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0032871943
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Tear fluid gelatinase B activity correlates with IL-1α concentration and fluorescein tear clearance
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Afonso A, Sobrin L, Monroy DC, et al. Tear fluid gelatinase B activity correlates with IL-1α concentration and fluorescein tear clearance. Invest Ophthalmol Vis Sci 1999; 40:2506-2512.
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(1999)
Invest Ophthalmol Vis Sci
, vol.40
, pp. 2506-2512
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Afonso, A.1
Sobrin, L.2
Monroy, D.C.3
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14
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9644272508
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Conjunctival epithelial cell expression of interleukins and inflammatory markers in glaucoma patients treated over the long term
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Baudouin C, Hamard P, Liang H, et al. Conjunctival epithelial cell expression of interleukins and inflammatory markers in glaucoma patients treated over the long term. Ophthalmology 2004; 111:2186-2192.
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(2004)
Ophthalmology
, vol.111
, pp. 2186-2192
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Baudouin, C.1
Hamard, P.2
Liang, H.3
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15
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33745362862
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Effects of topical antiglaucoma application on conjunctival impression cytology specimens
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Hong S, Lee CS, Seo KY, et al. Effects of topical antiglaucoma application on conjunctival impression cytology specimens. Am J Ophthalmol 2006; 142: 185-186.
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(2006)
Am J Ophthalmol
, vol.142
, pp. 185-186
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Hong, S.1
Lee, C.S.2
Seo, K.Y.3
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16
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0031729782
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The pathology of dry eye: The interaction between ocular surface and lacrimal glands
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Stern ME, Beuerman RW, Fox RI, et al. The pathology of dry eye: the interaction between ocular surface and lacrimal glands. Cornea 1998; 17: 584-589.
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(1998)
Cornea
, vol.17
, pp. 584-589
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Stern, M.E.1
Beuerman, R.W.2
Fox, R.I.3
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17
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34247641102
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Mrugacz M, Zak J, Bakunowicz-Lazarczyk A, et al. ICAM-1 expression on conjunctival epithelial cells in patients with cystic fibrosis. Cytometry B Clin Cytom 2007; 72:204-208. Similar to other dry eye diseases, dry eye associated with cystic fibrosis stimulates production of the adhesion molecule ICAM-1 by the conjunctival epithelium.
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Mrugacz M, Zak J, Bakunowicz-Lazarczyk A, et al. ICAM-1 expression on conjunctival epithelial cells in patients with cystic fibrosis. Cytometry B Clin Cytom 2007; 72:204-208. Similar to other dry eye diseases, dry eye associated with cystic fibrosis stimulates production of the adhesion molecule ICAM-1 by the conjunctival epithelium.
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18
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34548697527
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Mrugacz M, Zak J, Bakunowicz-Lazarczyk A, et al. Flow cytometric analysis of HLA-DR antigen in conjunctival epithelial cells of patients with cystic fibrosis. Eye 2006; 19 May [Epub ahead of print]. Similar to other dry eye diseases, dry eye associated with cystic fibrosis stimulates production of the immune activation molecule HLA-DR by the conjunctival epithelium.
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Mrugacz M, Zak J, Bakunowicz-Lazarczyk A, et al. Flow cytometric analysis of HLA-DR antigen in conjunctival epithelial cells of patients with cystic fibrosis. Eye 2006; 19 May [Epub ahead of print]. Similar to other dry eye diseases, dry eye associated with cystic fibrosis stimulates production of the immune activation molecule HLA-DR by the conjunctival epithelium.
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19
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28044454795
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Distribution of conjunctival HLA-DR expression and the pathogenesis of damage in early dry eyes
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Rolando M, Barabino S, Mingari C, et al. Distribution of conjunctival HLA-DR expression and the pathogenesis of damage in early dry eyes. Cornea 2005; 24:951-954.
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(2005)
Cornea
, vol.24
, pp. 951-954
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Rolando, M.1
Barabino, S.2
Mingari, C.3
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20
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0033781588
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Flow cytometric analysis of conjunctival epithelium in ocular rosacea and keratoconjunctivitis sicca
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Pisella PJ, Brignole F, Debbasch C, et al. Flow cytometric analysis of conjunctival epithelium in ocular rosacea and keratoconjunctivitis sicca. Ophthalmology 2000; 107:1841-1849.
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(2000)
Ophthalmology
, vol.107
, pp. 1841-1849
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Pisella, P.J.1
Brignole, F.2
Debbasch, C.3
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21
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33845976678
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Evaluation and treatment of children with ocular rosacea
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Donaldson KE, Karp CL, Dunbar MT. Evaluation and treatment of children with ocular rosacea. Cornea 2007; 26:42-46.
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(2007)
Cornea
, vol.26
, pp. 42-46
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Donaldson, K.E.1
Karp, C.L.2
Dunbar, M.T.3
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22
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33745119413
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Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye
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Indicates that doxycycline, an agent that has been used to treat ocular surface diseases for decades, has potent antiinflammatory effects
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De Paiva CS, Corrales RM, Villarreal AL, et al. Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye. Exp Eye Res 2006; 83:526-535. Indicates that doxycycline, an agent that has been used to treat ocular surface diseases for decades, has potent antiinflammatory effects.
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(2006)
Exp Eye Res
, vol.83
, pp. 526-535
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De Paiva, C.S.1
Corrales, R.M.2
Villarreal, A.L.3
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23
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31044455375
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JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells
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Li DQ, Luo L, Chen Z, et al. JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells. Exp Eye Res 2006; 82:588-596.
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(2006)
Exp Eye Res
, vol.82
, pp. 588-596
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Li, D.Q.1
Luo, L.2
Chen, Z.3
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24
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33645887506
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Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure
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The findings indicate that inflammation is a risk factor for failure of glaucoma filtering blebs
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Ah-Chan JJ, Molteno AC, Bevin TH. Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure. Arch Ophthalmol 2006; 124:60. The findings indicate that inflammation is a risk factor for failure of glaucoma filtering blebs.
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(2006)
Arch Ophthalmol
, vol.124
, pp. 60
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Ah-Chan, J.J.1
Molteno, A.C.2
Bevin, T.H.3
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25
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33645999705
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Chitosan nanoparticles as a potential drug delivery system for the ocular surface: Toxicity, uptake mechanism and in vivo tolerance
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This is an exciting nanoparticle technology for delivery of therapeutic agents to the corneal and conjunctival epithelia
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Enriquez de Salamanca A, Diebold Y, Calonge M, et al. Chitosan nanoparticles as a potential drug delivery system for the ocular surface: toxicity, uptake mechanism and in vivo tolerance. Invest Ophthalmol Vis Sci 2006; 47:1416-1425. This is an exciting nanoparticle technology for delivery of therapeutic agents to the corneal and conjunctival epithelia.
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(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 1416-1425
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Enriquez de Salamanca, A.1
Diebold, Y.2
Calonge, M.3
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26
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33646692939
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Gomes dos Santos AL, Bochot A, Doyle A, et al. Sustained release of nanosized complexes of polyethylenimine and anti-TGF-beta 2 oligonucleotide improves the outcome of glaucoma surgery. J Control Release 2006; 112:369-381
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Gomes dos Santos AL, Bochot A, Doyle A, et al. Sustained release of nanosized complexes of polyethylenimine and anti-TGF-beta 2 oligonucleotide improves the outcome of glaucoma surgery. J Control Release 2006; 112:369-381.
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