Measurement of inflammatory cytokines by multicytokine assay in tears of patients with glaucoma topically treated with chronic drugs

British Journal of Ophthalmology

Volumn 91, Issue 1, 2007, Pages 29-32

  Malvitte, L ^a,b   Montange, T ^b   Vejux, A ^b   Baudouin, C ^c   Bron, A M ^a   Creuzot Garcher, C ^a   Lizard, G ^b  

^a DIJON UNIVERSITY HOSPITAL   (France)

^b INSERM   (France)

^c CENTRE HOSPITALIER NATIONAL D OPHTALMOLOGIE DES QUINZE VINGTS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIMATOPROST; BRIMONIDINE; CARTEOLOL; CYTOKINE; DORZOLAMIDE; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; LATANOPROST; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PILOCARPINE; TIMOLOL; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GLAUCOMA; HUMAN; IMMUNOASSAY; LACRIMAL FLUID; PRIORITY JOURNAL;

ADMINISTRATION, TOPICAL; AGED; AMIDES; ANTIHYPERTENSIVE AGENTS; CARTEOLOL; CASE-CONTROL STUDIES; CHEMOKINES; CLOPROSTENOL; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; DRUG THERAPY, COMBINATION; FEMALE; GLAUCOMA; HUMANS; INTRAOCULAR PRESSURE; LIPIDS; MALE; PROSPECTIVE STUDIES; PROSTAGLANDINS F, SYNTHETIC; QUINOXALINES; SULFONAMIDES; TEARS; THIOPHENES; TIMOLOL;

EID: 33846244951     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.2006.101485     Document Type: Article

References (21)

1. Baudouin C. Side effects of antiglaucomatous drugs on the ocular surface. Curr Opin Ophthalmol 1996;7:80-6.
2. Broadway D, Grierson I, Hitchings R. Adverse effects of topical antiglaucomatous medications on the conjunctiva. Br J Ophthalmol 1993;77:590-6.
3. Broadway D, Grierson I, O'Brien C, et al. Adverse effects of topical antiglaucoma medication. I. The conjunctival cell profile. Arch Ophthalmol 1994;112:1437-45.
4. Baudouin C. Mechanisms of failure in glaucoma filtering surgery: a consequence of antiglaucomatous drugs? Int J Clin Pharmacol Res 1996;16:29-41.
5. Guenoun JM, Baudouin C, Rat P, et al. In vitro study of inflammatory potential and toxicity profile of latanoprost, travoprost, and bimatoprost in conjunctiva-derived epithelial cells. Invest Ophthalmol Vis Sci 2005;46:2444-50.
6. Mietz H, Niesen U, Krieglstein GK. The effect of preservatives and antiglaucomatous medication on the histopathology of the conjunctiva. Graefe's Arch Clin Exp Ophthalmol 1994;232:561-5.
7. Cook EB, Stahl JL, Lowe L, et al. Simultaneous measurement of six cytokines in a single sample of human tears using microparticle-based flow cytometry: allergies vs. non-allergies. J Immunol Methods 2001;254:109-18.
8. Barton K, Monroy DC, Nava A, et al. Inflammatory cytokines in the tears of patients wild ocular rosacea. Ophthalmology 1997;104:1868-74.
9. Pflugfelder SC, Jones D, Ji Z, et al. Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjogren's syndrome keratoconjunctivitis sicca. Curr Eye Res 1999;19:201-11.
10. Wilson MR, Wotherspoon JS. A new microsphere-based immunofluorescence assay using flow cytometry. J Immunol Methods 1988;107:225-30.
11. Vignali DA. Multiplexed particle-based flow cytometric assays. J Immunol Methods 2000;243:243-55.
12. Noecker RJ, Herrygers LA, Anwaruddin R. Corneal and conjunctival changes caused by commonly used glaucoma medications. Cornea 2004;23:490-6.
13. Khan SS, Smith MS, Reda D, et al. Multiplex bead array assays for detection of soluble cytokines: comparisons of sensitivity and quantitative values among kits from multiple manufacturers. Cytometry B Clin Cytometry 2004;61:35-9.
14. DuPont NC, Wang K, Wadhwa PD, et al. Validation and comparison of luminex multiplex cytokine analysis kits with ELISA: determinations of a panel of nine cytokines in clinical sample culture supernatants. J Reprod Immunol 2005;66:175-91.
15. Uchino E, Sonoda S, Kinukawa N, et al. Alteration pattern of tear cytokines during the course of a day: diurnal rhythm analyzed by multicytokine assay. Cytokine 2006;33:36-40.
16. Baudouin C, Hamard P, Liang H, et al. Conjunctival epithelial cell expression of interleukins and inflammatory markers in glaucoma patients treated over the long term. Ophtalmology 2004;111:2186- 92.
17. De Saint-Jean M, Brignole F, Bringuier AF, et al. Effects of benzalkonium chloride on growth and survival of Chang conjunctival cells. Invest Ophthalmol Vis Sci 1999;40:619-30.
18. Pisella PJ, Fillacier K, Elena PP, et al. Comparison of the effects of preserved and unpreserved formulations of timolol on the ocular surface of albino rabbits. Ophthalmic Res 2000;32:3-8.
19. Nakamura Y, Sotozono C, Kinoshita S. Inflammatory cytokines in normal human tears. Curr Eye Res 1998;17:673-6.
20. Baudouin C, Liang H, Bremond-Gignac D, et al. CCR 4 and CCR 5 expression in conjunctival specimens as differential markers of T(H)1/T(H)2 in ocular surface disorders. J Allergy Clin Immunol 2005;116:614- 19.
21. Pisella PJ, Debbasch C, Hamard P, et al. Conjunctival proinflammatory and proapoptotic effects of latanoprost and preserved and unpreserved timolol: an ex vivo and in vitro study. Invest Ophthalmol Vis Sci 2004;45:1360-8.