Coimmunization with RANTES plasmid polarized Th1 immune response against hepatitis B virus envelope via recruitment of dendritic cells

Antiviral Research

Volumn 76, Issue 2, 2007, Pages 140-149

  Ma, Ke ^a,b   Xu, Wei ^a,b   Shao, Xianan ^a,b   YanYue, ^a,b   Hu, Linkun ^a   Xu, Huanbin ^a,b   Yuan, Zhigang ^a,b   Zheng, Xiujuan ^a,b   Xiong, Sidong ^a,b,c  

^a FUDAN UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c Shanghai Institute of Immunology   (China)

Author keywords

DC; DNA vaccine; HBV; RANTES; Th1

Indexed keywords

CHEMOKINE; DNA VACCINE; HEPATITIS B SURFACE ANTIGEN; PRES2 PROTEIN PLUS S PROTEIN; RANTES; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BAGG ALBINO MOUSE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MATURATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; FEMALE; GENETIC CODE; HEPATITIS B; HEPATITIS B VIRUS; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGENICITY; MOUSE; NONHUMAN; PHENOTYPE; PLASMID; POLARIZATION; PRIORITY JOURNAL; PROTEIN SECRETION; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH2 CELL; UPREGULATION; VACCINATION; VIRUS ENVELOPE;

ANIMALS; ANTIBODIES, VIRAL; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CHEMOKINE CCL5; CYTOTOXICITY TESTS, IMMUNOLOGIC; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; HEPATITIS B VIRUS; IMMUNIZATION, SECONDARY; MICE; MICE, INBRED BALB C; PLASMIDS; PROTEIN PRECURSORS; T-LYMPHOCYTE SUBSETS; VACCINES, DNA;

HEPATITIS B VIRUS;

EID: 34548604235     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.antiviral.2007.06.012     Document Type: Article

References (37)

1. Appay V., and Rowland-Jones S.L. RANTES: a versatile and controversial chemokine. Trends. Immunol. 22 (2001) 83-87
2. Ara Y., Saito T., Takagi T., Hagiwara E., Miyagi Y., Sugiyama M., Kawamoto S., Ishii N., Yoshida T., Hanashi D., Koshino T., Okada H., and Okuda K. Zymosan enhances the immune response to DNA vaccine for human immunodeficiency virus type-1 through the activation of complement system. Immunology 103 (2001) 98-105
3. Beckebaum S., Cicinnati V.R., and Gerken G. DNA-based immunotherapy: potential for treatment of chronic viral hepatitis?. Rev. Med. Virol. 12 (2002) 297-319
4. Bhatia S., Mukhopadhyay S., Jarman E., Hall G., George A., Basu S.K., Rath S., Lamb J.R., and Bal V. Scavenger receptor-specific allergen delivery elicits IFN-gamma-dominated immunity and directs established TH2-dominated responses to a nonallergic phenotype. J. Allergy. Clin. Immunol. 109 (2002) 321-328
5. Braciak T.A., Bacon K., Xing Z., Torry D.J., Graham F.L., Schall T.J., and Richards C.D. Overexpression of RANTES using a recombinant adenovirus vector induces the tissue-directed recruitment of monocytes to the lung. J. Immunol. 157 (1996) 5076-5084
6. Davis H.L., and McCluskie M.J. DNA vaccines for viral diseases. Microbes Infect. 1 (1999) 7-21
7. Doe B., Selby M., Barnett S., Baenziger J., and Walker C.M. Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells. Proc. Natl. Acad. Sci. USA. 93 (1996) 8578-8583
8. Eo S.K., Lee S., Kumaraguru U., and Barry T. Rouse. Immunopotentiation of DNA vaccine against herpes simplex virus via co-delivery of plasmid DNA expressing CCR7 ligands. Vaccine 19 (2001) 4685-4693
9. Fischer F.R., Luo Y., Luo M., Santambrogio L., and Dorf M.E. RANTES-induced chemokine cascade in dendritic cells. J. Immunol. 167 (2001) 1637-1643
10. Foti M., Granucci F., Aggujaro D., Liboi E., Luini W., Minardi S., Mantovani A., Sozzani S., and Ricciardi-Castagnoli P. Upon dendritic cell (DC) activation chemokines and chemokine receptor expression are rapidly regulated for recruitment and maintenance of DC at the inflammatory site. Int. Immunol. 11 (1999) 979-986
11. Fukada K., Sobao Y., Tomiyama H., Oka S., and Takiguchi M. Functional expression of the chemokine receptor CCR5 on virus epitope-specific memory and effector CD8+ T cells. J. Immunol. 168 (2002) 2225-2232
12. Gurunathan S., Klinman D.M., and Seder R.A. DNA vaccines: immunology, application, and optimization. Annu. Rev. Immunol. 18 (2000) 927-974
13. Haddad D., Ramprakash J., Sedegah M., Charoenvit Y., Baumgartner R., Kumar S., Hoffman S.L., and Weiss W.R. Plasmid vaccine expressing granulocyte-macrophage colony-stimulating factor attracts infiltrates including immature dendritic cells into injected muscles. J. Immunol. 165 (2000) 3772-3781
14. Hauser H., Shen L., Gu Q.L., Krueger S., and Chen S.Y. Secretory heat-shock protein as a dendritic cell-targeting molecule: a new strategy to enhance the potency of genetic vaccines. Gene Ther. 11 (2004) 924-932
15. Hung C.F., Yang M., and Wu T.C. Modifying professional antigen-presenting cells to enhance DNA vaccine potency. Methods Mol. Med. 127 (2006) 199-220
16. Kim S.J., Suh D., Park S.E., Park J.S., Byun H.M., Lee C., Lee S.Y., Kim I., and Oh Y.K. Enhanced immunogenicity of DNA fusion vaccine encoding secreted hepatitis B surface antigen and chemokine RANTES. Virology 314 (2003) 84-91
17. Kim T.W., Hung C.F., Boyd D., Juang J., He L., Kim J.W., Hardwick J.M., and Wu T.C. Enhancing DNA vaccine potency by combining a strategy to prolong dendritic cell life with intracellular targeting strategies. J. Immunol. 171 (2003) 2970-2976
18. Kwon T.K., and Park J.W. Intramuscular co-injection of naked DNA encoding HBV core antigen and Flt3 ligand suppresses anti-HBc antibody response. Immunol. Lett. 81 (2002) 229-234
19. Loi P.K., Mcgraw H.F., and Tublitz N.J. Peptide detection in single cells using a dot immunoblot assay. Peptides 18 (1997) 749-753
20. Lillard J.W., Boyaka P.N., Taub D.D., and McGhee J.R. RANTES potentiates antigen-specific mucosal immune responses. J. Immunol. 166 (2001) 162-169
21. McGuirk P., and Mills K.H. Pathogen-specific regulatory T cells provoke a shift in the Th1/Th2 paradigmin immunity to infectious diseases. Trends Immunol. 23 (2002) 450-455
22. Michel M.L., and Loirat D. DNA vaccines for prophylactic or therapeutic immunization against hepatitis B. Intervirology 44 (2001) 78-87
23. Michel M.L., and Mancini-Bourgine M. Therapeutic vaccination against chronic hepatitis B virus infection. J. Clin. Virol. 34 1 (2005) S108-S114
24. Mizukoshi E., Sidney J., Livingston B., Ghany M., Hoofnagle J.H., Sette A., and Rehermann B. Cellular immune responses to the hepatitis B virus polymerase. J. Immunol. 173 (2004) 5863-5871
25. Nayak B.P., Sailaja G., and Jabbar A.M. Augmenting the immunogenicity of DNA vaccines: role of plasmid-encoded Flt-3 ligand, as a molecular adjuvant in genetic vaccination. Virology 348 (2006) 277-288
26. O'Neill D.W., Adams S., and Bhardwaj N. Manipulating dendritic cell biology for the active immunotherapy of cancer. Blood 104 (2004) 2235-2246
27. Sang H., Pisarev V.M., Munger C., Robinson S., Chavez J., Hatcher L., Parajuli P., Guo Y., and Talmadge J.E. Regional, but not systemic recruitment/expansion of dendritic cells by a pluronic-formulated Flt3-ligand plasmid with vaccine adjuvant activity. Vaccine 21 (2003) 3019-3029
28. Sato Y., Roman M., Tighe H., Lee D., Corr M., Nguyen M.D., Silverman G.J., Lotz M., Carson D.A., and Raz E. Immunostimulatory DNA sequences necessary for effective intradermal gene immunization. Science 273 (1996) 352-354
29. Shimizu Y., Guidotti L.G., Fowler P., and Chisari F.V. Dendritic Cell Immunization Breaks Cytotoxic T Lymphocyte Tolerance in Hepatitis B Virus Transgenic Mice. J. Immunol. 161 (1998) 4520-4529
30. Shimizu Y., Inaba K., Kaneyasu K., Ibuki K., Himeno A., Okoba M., Goto Y., Hayami M., Miura T., and Haga T. A genetically engineered live-attenuated simian-human immunodeficiency virus that co-expresses the RANTES gene improves the magnitude of cellular immunity in rhesus macaques. Virology 361 (2007) 68-79
31. Sin J., Kim J.J., Pachuk C., Satishchandran C., and Weiner D.B. DNA vaccines encoding interleukin-8 and RANTES enhance antigen-specific Th1-type CD4(+) T-cell-mediated protective immunity against herpes simplex virus type 2 in vivo. J. Virol. 74 (2000) 11173-11180
32. Sin J.I., Kim J.J., Pachuk C., Satishchandran C., and Weiner D.B. DNA vaccines encoding interleukin-8 and RANTES enhance antigen-specific Th1-type CD4 T-cell-mediated protective immunity against herpes simplex virus type 2 in vivo. J. Virol. 74 (2000) 11173-11180
33. Thermet A., Rollier C., Zoulim F., Trepo C., and Cova L. Progress in DNA vaccine for prophylaxis and therapy of hepatitis B. Vaccine 1 (2003) 659-662
34. Waterman P.M., Kitabwalla M., Hatfield G.S., Evans P.S., Lu Y., Tikhonov I., Bryant J.L., and Pauza C.D. Effects of virus burden and chemokine expression on immunity to SHIV in nonhuman primates. Viral. Immunol. 17 (2004) 545-557
35. Xin K.Q., Lu Y., Hamajima K., Fukushima J., Yang J., Inamura K., and Okuda K. Immunization of RANTES expression plasmid with a DNA vaccine enhances HIV-1-specific immunity. Clin. Immunol. 92 (1999) 90-96
36. Yoon H.A., and Eo S.K. Differential polarization of immune responses by genetic cotransfer of chemokines changes the protective immunity of DNA vaccine against pseudorabies virus. Immunology 120 (2007) 182-191
37. You Z., Huang X., Hester J., Toh H.C., and Chen S.Y. Targeting dendritic cells to enhance DNA vaccine potency. Cancer Res. 61 (2001) 3704-3711