Performance measurement of the microPET focus 120 scanner

Journal of Nuclear Medicine

Volumn 48, Issue 9, 2007, Pages 1527-1535

  Jin, Su Kim ^a   Jae, Sung Lee ^a   Ki, Chun Im ^b   Su, Jin Kim ^a   Kim, Seog Young ^b   Dong, Soo Lee ^a   Dae, Hyuk Moon ^b  

^a Seoul National University College of Medicine   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

Author keywords

Instrumentation; Molecular imaging; Performance measurement; Small animal imaging; Small animal PET

Indexed keywords

FLUORODEOXYGLUCOSE F 18; GERMANIUM; GERMANIUM 68; SODIUM 22; UNCLASSIFIED DRUG;

ARTICLE; IMAGING SYSTEM; INSTRUMENTATION; MICRO POSITRON EMISSION TOMOGRAPHY; MOLECULAR IMAGING; MOUSE; NONHUMAN; PERFORMANCE MEASUREMENT SYSTEM; PHANTOM; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RAT;

ANIMALS; BONE AND BONES; BRAIN; CATS; FEASIBILITY STUDIES; FLUORINE RADIOISOTOPES; GERMANIUM; HEART; MICE; PHANTOMS, IMAGING; POSITRON-EMISSION TOMOGRAPHY; RADIOISOTOPES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 34548580353     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.107.040550     Document Type: Article

References (33)

1. Bateman TM. Cardiac positron emission tomography and the role of adenosine pharmacologic stress. Am J Cardiol. 2004;94:19D-24D.
2. 18F-FLT-PET in oncology: current status and opportunities. Eur J Nucl Med Mol Imaging. 2004;31:1659-1672.
3. Nordberg A. PET imaging of amyloid in Alzheimer's disease. Lancet Neurol. 2004;3:519-527.
4. Rohren EM, Turkington TG, Coleman RE. Clinical applications of PET in oncology. Radiology. 2004;231:305-332.
5. Phelps ME. Nuclear medicine, molecular imaging, and molecular medicine. J Nucl Med. 2002;43:13N-14N.
6. Pomper MG. Can small animal imaging accelerate drug development? J Cell Biochem Suppl. 2002;39:211-220.
7. Gambhir SS. Molecular imaging of cancer with positron emission tomography. Nat Rev Cancer. 2002;2:683-693.
8. Pomper MG, Lee JS. Small animal imaging in drug development. Curr Pharm Des. 2005;11:3247-3272.
9. Green MV, Seidel J, Vaquero JJ, Jagoda E, Lee I, Eckelman WC. High resolution PET, SPECT and projection imaging in small animals. Comput Med Imaging Graph. 2001;25:79-86.
10. Chatziioannou AF. PET scanners dedicated to molecular imaging of small animal models. Mol Imaging Biol. 2002;4:47-63.
11. Hume SP, Myers R. Dedicated small animal scanners: a new tool for drug development? Curr Pharm Des. 2002;8:1497-1511.
12. Tai YC, Ruangma A, Rowland D, et al. Performance evaluation of the microPET focus: a third-generation microPET scanner dedicated to animal imaging. J Nucl Med. 2005;46:455-455-463.
13. Laforest R, Longford D, Siegel S, Newport DF, Yap J. Performance evaluation of the microPET-Focus-F120. Conference Records IEEE Nuclear Science Symposium and Medical Imaging, Rome, Italy, October 16-22, 2004. Piscataway, NJ: IEEE; 2004.
14. Daube-Witherspoon ME, Muehllehner G. Treatment of axial data in three-dimensional PET. J Nucl Med. 1987;28:1717-1724.
15. Yao R, Seidel J, Johnson CA, Daube-Witherspoon ME, Green MV, Carson RE. Performance characteristics of the 3-D OSEM algorithm in the reconstruction of small animal PET images: ordered-subsets expectation-maximixation. IEEE Trans Med Imaging. 2000;19:798-804.
16. Kinahan PE, Rogers JG. Analytic 3D image reconstruction using all detected events. IEEE Trans Nucl Sci. 1989;36:964-968.
17. Qi J, Leahy RM, Cherry SR, Chatziioannou A, Farquhar TH. High-resolution 3D bayesian image reconstruction using the microPET small-animal scanner. Phys Med Biol. 1998;43:1001-1013.
18. Defrise M, Kinahan PE, Townsend DW, Michel C, Sibomana M, Newport DF. Exact and approximate rebinning algorithms for 3-D PET data. IEEE Trans Med Imaging. 1997;16:145-158.
19. Knoess C, Siegel S, Smith A, et al. Performance evaluation of the microPET R4 PET scanner for rodents. Eur J Nucl Med Mol Imaging. 2003;30:737-747.
20. Weber S, Bauer A. Small animal PET: aspects of performance assessment. Eur J Nucl Med Mol Imaging. 2004;31:1545-1555.
21. Badawi RD, Marsden PK. Developments in component-based normalization for 3D PET. Phys Med Biol. 1999;44:571-594.
22. Daube-Witherspoon ME, Karp JS, Casey ME, et al. PET performance measurements using the NEMA NU 2-2001 standard. J Nucl Med. 2002;43:1398-1409.
23. National Electrical Manufacturers Association. NEMA Standards Publication NU2-2001: Performance Measurements of Positron Emission Tomographs. Rosslyn, VA: National Electrical Manufacturers Association; 2001.
24. Watson CC, Casey ME, Eriksson L, Mulnix T, Adams D, Bendriem B. NEMA NU 2 performance tests for scanners with intrinsic radioactivity. J Nucl Med. 2004;45:822-826.
25. Erdi YE, Nehmeh SA, Mulnix T, Humm JL, Watson CC. PET performance measurements for an LSO-based combined PET/CT scanner using the National Electrical Manufacturers Association NU 2-2001 standard. J Nucl Med. 2004;45:813-821.
26. Eriksson L, Watson CC, Wienhard K, et al. The ECAT HRRT: an example of NEMA scatter estimation issues for LSO-based PET systems. IEEE Trans Nucl Sci. 2005;52:90-94.
27. Bailey DL, Jones T, Spinks TJ. A method for measuring the absolute sensitivity of positron emission tomographic scanners. Eur J Nucl Med. 1991;18:374-379.
28. Seidel J, Vaquero JJ, Lee IJ, Green MV. Experimental estimates of the absolute sensitivity of a small animal PET scanner with depth-of-interaction capability. Conference Records IEEE Nuclear Science Symposium and Medical Imaging, Lyon, France, October 15-20, 2000. Piscataway, NJ: IEEE; 2000.
29. Nuyts J, Dupont P, Stroobants S, Maes A, Mortelmans L, Suetens P. Evaluation of maximum-likelihood based attenuation correction in positron emission tomography. IEEE Trans Nucl Sci. 1999;46:1136-1141.
30. Moses WW, Derenzo SE. Empirical observation of resolution degradation on positron emission tomographs utilizing block detectors [abstract]. J Nucl Med. 1993;34(suppl):101P
31. Tomic N, Thompson CJ, Casey ME. Investigation of the "block effect" on spatial resolution in PET detectors. IEEE Trans Nucl Sci. 2005;52:599-605.
32. International Commission on Radiation Units and Measurements. ICRU Report 37: Stopping Powers for Electrons and Positrons. Bethesda, MD: International Commission on Radiation Units and Measurements; 1984.
33. Wang Y, Seidel J, Tsui BM, Vaquero JJ, Pomper MG. Performance evaluation of the GE Healthcare eXplore VISTA dual-ring small-animal PET scanner. J Nucl Med. 2006;47:1891-1900.