Glucocorticoids for peri-operative analgesia: How far are we from general recommendations?

Acta Anaesthesiologica Scandinavica

Volumn 51, Issue 9, 2007, Pages 1133-1135

  Kehlet, H ^a  

^a Rigshospitalet   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; DEXAMETHASONE; GLUCOCORTICOID; INTERLEUKIN 6; KETOROLAC; METHYLPREDNISOLONE;

ABSENCE OF SIDE EFFECTS; ANALGESIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTHROSCOPIC SURGERY; BURN; CHOLECYSTECTOMY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; EDITORIAL; FATIGUE; HUMAN; HYPERESTHESIA; INFECTIOUS ARTHRITIS; PAIN; PAIN THRESHOLD; POSTOPERATIVE NAUSEA AND VOMITING; PRIORITY JOURNAL; PROPHYLAXIS; TONSILLECTOMY; UNSPECIFIED SIDE EFFECT;

ANALGESIA; ANALGESICS; GLUCOCORTICOIDS; HUMANS; PAIN, POSTOPERATIVE; POSTOPERATIVE NAUSEA AND VOMITING;

EID: 34548550910     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2007.01459.x     Document Type: Editorial

References (29)

1. Rhen T, Cidlowski JA. Antiinflammatory action of glucocorticoids - new mechanisms for old drugs. N Engl J Med 2005 353 : 1711 23.
2. Gilron I. Corticosteroids in postoperative pain management: future research directions for a multifaceted therapy. Acta Anaesthesiol Scand 2004 48 : 1221 2.
3. Henzi I, Walder B, Tramer MR. Dexamethasone for the prevention of postoperative nausea and vomiting: a quantitative systematic review. Anesth Analg 2000 90 : 186 94.
4. Holte K, Kehlet H. Perioperative single-dose glucocorticoid administration: pathophysiologic effects and clinical implications. J Am Coll Surg 2002 195 : 694 712.
5. Apfel CC, Korttila K, Abdalla M, Sessler DI, Roewer N. A factorial trial of six interventions for the prevention of postoperative nausea and vomiting. N Engl J Med 2004 350 : 2441 51.
6. Stubhaug A, Romundstad L, Kaasa T, Breivik H. Methylprednisolone and ketorolac rapidly reduce hyperalgesia around a skin burn injury and increase pressure pain thresholds. Acta Anaesthesiol Scand 2007 51 : 1138 46.
7. Romundstad L, Breivik H, Roald H et al. Methylprednisolone reduces pain, emesis, and fatigue after breast augmentation surgery: a single-dose, randomized, parallel-group study with methylprednisolone 125 mg, parecoxib 40 mg, and placebo. Anesth Analg 2006 102 : 418 25.
8. Romundstad L, Breivik H, Roald H, Skolleborg K, Romundstad PR, Stubhaug A. Chronic pain and sensory changes after augmentation mammoplasty: long term effects of preincisional administration of methylprednisolone. Pain 2006 124 : 92 9.
9. Romundstad L, Breivik H, Niemi G, Helle A, Stubhaug A. Methylprednisolone intravenously 1 day after surgery has sustained analgesic and opioid-sparing effects. Acta Anaesthesiol Scand 2004 48 : 1223 31.
10. Bisgaard T, Klarskov B, Kehlet H, Rosenberg J. Preoperative dexamethasone improves surgical outcome after laparoscopic cholecystectomy: a randomized double-blind placebo-controlled trial. Ann Surg 2003 238 : 651 60.
11. Vargas JH III., Ross DG. Corticosteroids and anterior cruciate ligament repair. Am J Sports Med 1989 17 : 532 4.
12. Wang JJ, Ho ST, Lee SC, Tang JJ, Liaw WJ. Intraarticular triamcinolone acetonide for pain control after arthroscopic knee surgery. Anesth Analg 1998 87 : 1113 6.
13. Rasmussen S, Larsen AS, Thomsen ST, Kehlet H. Intra-articular glucocorticoid, bupivacaine and morphine reduces pain, inflammatory response and convalescence after arthroscopic meniscectomy. Pain 1998 78 : 131 4.
14. Rasmussen S, Kehlet H. Intraarticular glucocorticoid, morphine and bupivacaine reduces pain and convalescence after arthroscopic ankle surgery: a randomized study of 36 patients. Acta Orthop Scand 2000 71 : 301 4.
15. Rasmussen S, Lorentzen JS, Larsen AS, Thomsen ST, Kehlet H. Combined intra-articular glucocorticoid, bupivacaine and morphine reduces pain and convalescence after diagnostic knee arthroscopy. Acta Orthop Scand 2002 73 : 175 8.
16. Kizilkaya M, Yildirim OS, Dogan N, Kursad H, Okur A. Analgesic effects of intraarticular sufentanil and sufentanil plus methylprednisolone after arthroscopic knee surgery. Anesth Analg 2004 98 : 1062 5.
17. Kizilkaya M, Yildirim OS, Ezirmik N, Kursad H, Karsan O. Comparisons of analgesic effects of different doses of morphine and morphine plus methylprednisolone after knee surgery. Eur J Anaesthesiol 2005 22 : 603 8.
18. Afman CE, Welge JA, Steward DL. Steroids for post-tonsillectomy pain reduction: meta-analysis of randomized controlled trials. Otolaryngol Head Neck Surg 2006 134 : 181 6.
19. Steward DL, Welge JA, Myer CM. Steroids for improving recovery following tonsillectomy in children. Cochrane Database Syst Rev 2003 : CD003997.
20. Kim MS, Cote CJ, Cristoloveanu C et al. There is no dose-escalation response to dexamethasone (0.0625-1.0 mg/kg) in pediatric tonsillectomy or adenotonsillectomy patients for preventing vomiting, reducing pain, shortening time to first liquid intake, or the incidence of voice change. Anesth Analg 2007 104 : 1052 8.
21. Shang AB, Gan TJ. Optimising postoperative pain management in the ambulatory patient. Drugs 2003 63 : 855 67.
22. Watters WC III., Temple AP, Granberry M. The use of dexamethasone in primary lumbar disc surgery. A prospective, randomized, double-blind study. Spine 1989 14 : 440 2.
23. Foulkes GD, Robinson JS Jr. Intraoperative dexamethasone irrigation in lumbar microdiskectomy. Clin Orthop Relat Res 1990 261 : 224 8.
24. Mirzai H, Tekin I, Alincak H. Perioperative use of corticosteroid and bupivacaine combination in lumbar disc surgery: a randomized controlled trial. Spine 2002 27 : 343 6.
25. Lundin A, Magnuson A, Axelsson K, Kogler H, Samuelsson L. The effect of perioperative corticosteroids on the outcome of microscopic lumbar disc surgery. Eur Spine J 2003 12 : 625 30.
26. Karst M, Kegel T, Lukas A, Ludemann W, Hussein S, Piepenbrock S. Effect of celecoxib and dexamethasone on postoperative pain after lumbar disc surgery. Neurosurgery 2003 53 : 331 6.
27. Salerno A, Hermann R. Efficacy and safety of steroid use for postoperative pain relief. Update and review of the medical literature. J Bone Joint Surg Am 2006 88 : 1361 72.
28. Halonen J, Halonen P, Jarvinen O et al. Corticosteroids for the prevention of atrial fibrillation after cardiac surgery: a randomized controlled trial. JAMA 2007 297 : 1562 7.
29. Sauerland S, Nagelschmidt M, Mallmann P, Neugebauer EA. Risks and benefits of preoperative high dose methylprednisolone in surgical patients: a systematic review. Drug Saf 2000 23 : 449 61.