Promotor elements governing the clustered expression pattern of odorant receptor genes

Molecular and Cellular Neuroscience

Volumn 36, Issue 1, 2007, Pages 95-107

  Zhang, Yong Quan ^a   Breer, Heinz ^a   Strotmann, Joerg ^a  

^a UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

Expression control; Mouse; Odorant receptor; Transgene

Indexed keywords

ODORANT RECEPTOR; RECEPTOR; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; C57BL 6 MOUSE; CELL LINE; FEMALE; GENE EXPRESSION; MOUSE; MOUSE STRAIN; NERVE FIBER; NONHUMAN; OLFACTORY SYSTEM; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENE; TURBINATE;

ANIMALS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU HYBRIDIZATION, FLUORESCENCE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; OLFACTORY BULB; OLFACTORY PATHWAYS; OLFACTORY RECEPTOR NEURONS; PROMOTER REGIONS (GENETICS); RECEPTORS, ODORANT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 34548509466     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2007.06.005     Document Type: Article

References (51)

1. Barnea G., O'Donnell S., Mancia F., Sun X., Nemes A., Mendelsohn M., and Axel R. Odorant receptors on axon termini in the brain. Science 304 (2004) 1468
2. Bozza T., Feinstein P., Zheng C., and Mombaerts P. Odorant receptor expression defines functional units in the mouse olfactory system. J. Neurosci. 22 (2002) 3033-3043
3. Buck L., and Axel R. A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell 65 (1991) 175-187
4. Chess A., Simon I., Cedar H., and Axel R. Allelic inactivation regulates olfactory receptor gene expression. Cell 78 (1994) 823-834
5. Ebrahimi F.A., and Chess A. Olfactory neurons are interdependent in maintaining axonal projections. Curr. Biol. 10 (2000) 219-222
6. Feinstein P., and Mombaerts P. A contextual model for axonal sorting into glomeruli in the mouse olfactory system. Cell 117 (2004) 817-831
7. Feinstein P., Bozza T., Rodriguez I., Vassalli A., and Mombaerts P. Axon guidance of mouse olfactory sensory neurons by odorant receptors and the beta2 adrenergic receptor. Cell 117 (2004) 833-846
8. Forrester W.C., Takegawa S., Papayannopoulou T., Stamatoyannopoulos G., and Groudine M. Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids. Nucleic Acids Res. 15 (1987) 10159-10177
9. Godfrey P.A., Malnic B., and Buck L.B. The mouse olfactory receptor gene family. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 2156-2161
10. Grosveld F., van Assendelft G.B., Greaves D.R., and Kollias G. Position-independent, high level expression of the human β-globin gene in transgenic mice. Cell 51 (1987) 975-985
11. Hoppe R., Weimer M., Beck A., Breer H., and Strotmann J. Sequence analyses of the olfactory receptor gene cluster mOR37 on mouse chromosome 4. [in process citation]. Genomics 66 (2000) 284-295
12. Hoppe R., Breer H., and Strotmann J. Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human. Genomics 82 (2003) 355-364
13. Hoppe R., Frank H., Breer H., and Strotmann J. The clustered olfactory receptor gene family 262: genomic organization, promotor elements, and interacting transcription factors. Genome Res. 13 (2003) 2674-2685
14. Hoppe R., Breer H., and Strotmann J. Promoter motifs of olfactory receptor genes expressed in distinct topographic patterns. Genomics 87 (2006) 711-723
15. Imai T., Suzuki M., and Sakano H. Odorant receptor-derived cAMP signals direct axonal targeting. Science 314 (2006) 657-661
16. Ishii T., Serizawa S., Kohda A., Nakatani H., Shiroishi T., Okumura K., Iwakura Y., Nagawa F., Tsuboi A., and Sakano H. Monoallelic expression of the odourant receptor gene and axonal projection of olfactory sensory neurones. Genes Cells 6 (2001) 71-78
17. Iwema C.L., Fang H., Kurtz D.B., Youngentob S.L., and Schwob J.E. Odorant receptor expression patterns are restored in lesion-recovered rat olfactory epithelium. J. Neurosci. 24 (2004) 356-369
18. Kubick S., Strotmann J., Andreini I., and Breer H. Subfamily of olfactory receptors characterized by unique structural features and expression patterns. J. Neurochem. 69 (1997) 465-475
19. Levai O., Breer H., and Strotmann J. Subzonal organization of olfactory sensory neurons projecting to distinct glomeruli within the mouse olfactory bulb. J. Comp. Neurol. 458 (2003) 209-220
20. Lewcock J.W., and Reed R.R. A feedback mechanism regulates monoallelic odorant receptor expression. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 1069-1075
21. Lomvardas S., Barnea G., Pisapia D.J., Mendelsohn M., Kirkland J., and Axel R. Interchromosomal interactions and olfactory receptor choice. Cell 126 (2006) 403-413
22. Malnic B., Hirono J., Sato T., and Buck L.B. Combinatorial receptor codes for odors. Cell 96 (1999) 713-723
23. Malnic B., Godfrey P.A., and Buck L.B. The human olfactory receptor gene family. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 2584-2589
24. Michaloski J.S., Galante P.A., and Malnic B. Identification of potential regulatory motifs in odorant receptor genes by analysis of promoter sequences. Genome Res. 16 (2006) 1091-1098
25. Miyamichi K., Serizawa S., Kimura H.M., and Sakano H. Continuous and overlapping expression domains of odorant receptor genes in the olfactory epithelium determine the dorsal/ventral positioning of glomeruli in the olfactory bulb. J. Neurosci. 25 (2005) 3586-3592
26. Mombaerts P. Genes and ligands for odorant, vomeronasal and taste receptors. Nat. Rev., Neurosci. 5 (2004) 263-278
27. Mombaerts P. Axonal wiring in the mouse olfactory system. Annu. Rev. Cell Dev. Biol. 22 (2006) 713-737
28. Mombaerts P., Wang F., Dulac C., Chao S.K., Nemes A., Mendelsohn M., Edmondson J., and Axel R. Visualizing an olfactory sensory map. Cell 87 (1996) 675-686
29. Pyrski M., Xu Z., Walters E., Gilbert D.J., Jenkins N.A., Copeland N.G., and Margolis F.L. The OMP-lacZ transgene mimics the unusual expression pattern of OR-Z6, a new odorant receptor gene on mouse chromosome 6: implication for locus-dependent gene expression. J. Neurosci. 21 (2001) 4637-4648
30. Qasba P., and Reed R.R. Tissue and zonal-specific expression of an olfactory receptor transgene. J. Neurosci. 18 (1998) 227-236
31. Ressler K.J., Sullivan S.L., and Buck L.B. A zonal organization of odorant receptor gene expression in the olfactory epithelium. Cell 73 (1993) 597-609
32. Ressler K.J., Sullivan S.L., and Buck L.B. Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Cell 79 (1994) 1245-1255
33. Rothman A., Feinstein P., Hirota J., and Mombaerts P. The promoter of the mouse odorant receptor gene M71. Mol. Cell. Neurosci. 28 (2005) 535-546
34. Sambrook J., Frisch E.F., and Maniatis T. Molecular Cloning: A Laboratory Manual (1989), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
35. Serizawa S., Ishii T., Nakatani H., Tsuboi A., Nagawa F., Asano M., Sudo K., Sakagami J., Sakano H., Ijiri T., Matsuda Y., Suzuki M., Yamamori T., Iwakura Y., and Sakano H. Mutually exclusive expression of odorant receptor transgenes. Nat. Neurosci. 3 (2000) 687-693
36. Serizawa S., Miyamichi K., Nakatani H., Suzuki M., Saito M., Yoshihara Y., and Sakano H. Negative feedback regulation ensures the one receptor-one olfactory neuron rule in mouse. Science 302 (2003) 2088-2094
37. Shykind B.M., Rohani S.C., O'Donnell S., Nemes A., Mendelsohn M., Sun Y., Axel R., and Barnea G. Gene switching and the stability of odorant receptor gene choice. Cell 117 (2004) 801-815
38. Strotmann J., and Breer H. Formation of glomerular maps in the olfactory system. Semin. Cell Dev. Biol. 17 (2006) 402-410
39. Strotmann J., Wanner I., Krieger J., Raming K., and Breer H. Expression of odorant receptors in spatially restricted subsets of chemosensory neurones. NeuroReport 3 (1992) 1053-1056
40. Strotmann J., Wanner I., Helfrich T., Beck A., and Breer H. Rostro-caudal patterning of receptor-expressing olfactory neurones in the rat nasal cavity. Cell Tissue Res. 278 (1994) 11-20
41. Strotmann J., Wanner I., Helfrich T., Beck A., Meinken C., Kubick S., and Breer H. Olfactory neurones expressing distinct odorant receptor subtypes are spatially segregated in the nasal neuroepithelium. Cell Tissue Res. 276 (1994) 429-438
42. Strotmann J., Hoppe R., Conzelmann S., Feinstein P., Mombaerts P., and Breer H. Small subfamily of olfactory receptor genes: structural features, expression pattern and genomic organization. Gene 236 (1999) 281-291
43. Strotmann J., Conzelmann S., Beck A., Feinstein P., Breer H., and Mombaerts P. Local permutations in the glomerular array of the mouse olfactory bulb. J. Neurosci. 20 (2000) 6927-6938
44. Strotmann J., Levai O., Fleischer J., Schwarzenbacher K., and Breer H. Olfactory receptor proteins in axonal processes of chemosensory neurons. J. Neurosci. 24 (2004) 7754-7761
45. Touhara K., Sengoku S., Inaki K., Tsuboi A., Hirono J., Sato T., Sakano H., and Haga T. Functional identification and reconstitution of an odorant receptor in single olfactory neurons. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 4040-4045
46. Vassalli A., Rothman A., Feinstein P., Zapotocky M., and Mombaerts P. Minigenes impart odorant receptor-specific axon guidance in the olfactory bulb. Neuron 35 (2002) 681
47. Vassar R., Ngai J., and Axel R. Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium. Cell 74 (1993) 309-318
48. Vassar R., Chao S.K., Sitcheran R., Nunez J.M., Vosshall L.B., and Axel R. Topographic organization of sensory projections to the olfactory bulb. Cell 79 (1994) 981-991
49. Wang F., Nemes A., Mendelsohn M., and Axel R. Odorant receptors govern the formation of a precise topographic map. Cell 93 (1998) 47-60
50. Young J.M., and Trask B.J. The sense of smell: genomics of vertebrate odorant receptors. Hum. Mol. Genet. 11 (2002) 1153-1160
51. Zhang X., and Firestein S. The olfactory receptor gene superfamily of the mouse. Nat. Neurosci. 5 (2002) 124-133