HMGA2 expression in a canine model of prostate cancer

Cancer Genetics and Cytogenetics

Volumn 177, Issue 2, 2007, Pages 98-102

  Winkler, Susanne ^a,b   Escobar, Hugo Murua ^b   Meyer, Britta ^a   Simon, Daniela ^b   Eberle, Nina ^b   Baumgartner, Wolfgang ^b   Loeschke, Siegfried ^a   Nolte, Ingo ^b   Bullerdiek, Jörn ^a  

^a UNIVERSITY OF BREMEN   (Germany)

^b UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH MOBILITY GROUP A2 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CONTROLLED STUDY; DISEASE COURSE; DOG; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC ANALYSIS; GENETIC CORRELATION; MALIGNANT TRANSFORMATION; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CANCER; PROSTATE CARCINOMA; REAL TIME POLYMERASE CHAIN REACTION;

ADENOCARCINOMA; ANIMALS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DOGS; GENE EXPRESSION REGULATION, NEOPLASTIC; HMGA2 PROTEIN; MALE; NEOPLASM INVASIVENESS; PROSTATE; PROSTATIC HYPERPLASIA; PROSTATIC NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

ANIMALIA; CANIS FAMILIARIS; MAMMALIA;

EID: 34548479534     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2007.06.008     Document Type: Article

References (30)

1. Brundtland GH, World Health Organization, Geneva, 2001.
2. Mettlin C.J., Murphy G.P., Rosenthal D.S., and Menck H.R. The National Cancer Data Base report on prostate carcinoma after the peak in incidence rates in the U.S. The American College of Surgeons Commission on Cancer and the American Cancer Society. Cancer 83 (1998) 1679-1684
3. Online publication, American Cancer Society. Statistics. available at http://www.cancer.org/docroot/stt/stt_0.asp Accessed 2007.
4. Boutemmine D., Bouchard N., Boerboom D., Jones H.E., Goff A.K., Dore M., and Sirois J. Molecular characterization of canine prostaglandin G/H synthase-2 and regulation in prostatic adenocarcinoma cells in vitro. Endocrinology 143 (2002) 1134-1143
5. Nolte I., and Nolte M. Praxis der Onkologie bei Hund und Katze (2000), Enke, Stuttgart
6. MacEwen E.G. Spontaneous tumors in dogs and cats: models for the study of cancer biology and treatment. Cancer Metastasis Rev 9 (1990) 125-136
7. Tamimi Y., van der Poel H.G., Denyn M.M., Umbas R., Karthaus H.F., Debruyne F.M., and Schalken J.A. Increased expression of high mobility group protein I(Y) in high grade prostatic cancer determined by in situ hybridization. Cancer Res 53 (1993) 5512-5516
8. Wanschura S., Kazmierczak B., Schoenmakers E., Meyen E., Bartnitzke S., Van de Ven W., Bullerdiek J., and Schloot W. Regional fine mapping of the multiple-aberration region involved in uterine leiomyoma, lipoma, and pleomorphic adenoma of the salivary gland to 12q15. Genes Chromosomes Cancer 14 (1995) 68-70
9. Wisniewski J.R., and Schwanbeck R. High mobility group I/Y: multifunctional chromosomal proteins causally involved in tumor progression and malignant transformation (review). Int J Mol Med 6 (2000) 409-419
10. Pentimalli F., Dentice M., Fedele M., Pierantoni G.M., Cito L., Pallante P., Santoro M., Viglietto G., Dal Cin P., and Fusco A. Suppression of HMGA2 protein synthesis could be a tool for the therapy of well differentiated liposarcomas overexpressing HMGA2. Cancer Res 63 (2003) 7423-7427
11. Rogalla P., Drechsler K., Frey G., Hennig Y., Helmke B., Bonk U., and Bullerdiek J. HMGI-C expression patterns in human tissues Implications for the genesis of frequent mesenchymal tumors. Am J Pathol 149 (1996) 775-779
12. Ashar H.R., Fejzo M.S., Tkachenko A., Zhou X., Fletcher J.A., Weremowicz S., Morton C.C., and Chada K. Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains. Cell 82 (1995) 57-65
13. Bullerdiek J., Wobst G., Meyer-Bolte K., Chilla R., Haubrich J., Thode B., and Bartnitzke S. Cytogenetic subtyping of 220 salivary gland pleomorphic adenomas: correlation to occurrence, histological subtype, and in vitro cellular behavior. Cancer Genet Cytogenet 65 (1993) 27-31
14. Hennig Y., Deichert U., Bonk U., Thode B., Bartnitzke S., and Bullerdiek J. Chromosomal translocations affecting 12q14-15 but not deletions of the long arm of chromosome 7 associated with a growth advantage of uterine smooth muscle cells. Mol Hum Reprod 5 (1999) 1150-1154
15. Hennig Y., Wanschura S., Deichert U., Bartnitzke S., and Bullerdiek J. Rearrangements of the high mobility group protein family genes and the molecular genetic origin of uterine leiomyomas and endometrial polyps. Mol Hum Reprod 2 (1996) 277-283
16. Kazmierczak B., Hennig Y., Wanschura S., Rogalla P., Bartnitzke S., Van de Ven W., and Bullerdiek J. Description of a novel fusion transcript between HMGI-C, a gene encoding for a member of the high mobility group proteins, and the mitochondrial aldehyde dehydrogenase gene. Cancer Res 55 (1995) 6038-6039
17. Kazmierczak B., Wanschura S., Rosigkeit J., Meyer-Bolte K., Uschinsky K., Haupt R., Schoenmakers E.F., Bartnitzke S., Van de Ven W.J., and Bullerdiek J. Molecular characterization of 12q14∼q15 rearrangements in three pulmonary chondroid hamartomas. Cancer Res 55 (1995) 2497-2499
18. Schoenmakers E.F., Wanschura S., Mols R., Bullerdiek J., Van den Berghe H., and Van de Ven W.J. Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours. Nat Genet 10 (1995) 436-444
19. Battista S., Fidanza V., Fedele M., Klein-Szanto A.J., Outwater E., Brunner H., Santoro M., Croce C.M., and Fusco A. The expression of a truncated HMGI-C gene induces gigantism associated with lipomatosis. Cancer Res 59 (1999) 4793-4797
20. Gross K.L., Neskey D.M., Manchanda N., Weremowicz S., Kleinman M.S., Nowak R.A., Ligon A.H., Rogalla P., Drechsler K., Bullerdiek J., and Morton C.C. HMGA2 expression in uterine leiomyomata and myometrium: quantitative analysis and tissue culture studies. Genes Chromosomes Cancer 38 (2003) 68-79
21. Walker-Daniels J., Coffman K., Azimi M., Rhim J.S., Bostwick D.G., Snyder P., Kerns B.J., Waters D.J., and Kinch M.S. Overexpression of the EphA2 tyrosine kinase in prostate cancer. Prostate 41 (1999) 275-280
22. Miyazawa J., Mitoro A., Kawashiri S., Chada K.K., and Imai K. Expression of mesenchyme-specific gene HMGA2 in squamous cell carcinomas of the oral cavity. Cancer Res 64 (2004) 2024-2029
23. Rogalla P., Drechsler K., Kazmierczak B., Rippe V., Bonk U., and Bullerdiek J. Expression of HMGI-C, a member of the high mobility group protein family, in a subset of breast cancers: relationship to histologic grade. Mol Carcinogen 19 (1997) 153-156
24. Meyer B., Loeschke S., Schultze A., Weigel T., Sandkamp M., Goldmann T., Vollmer E., and Bullerdiek J. HMGA2 Overexpression in non-small cell lung Cancer. Mol Carcinogen 46 (2007) 503-511
25. Abe N., Watanabe T., Sugiyama M., Uchimura H., Chiappetta G., Fusco A., and Atomi Y. Determination of high mobility group I(Y) expression level in colorectal neoplasias: a potential diagnostic marker. Cancer Res 59 (1999) 1169-1174
26. Sarhadi V., Wikman H., Salmenkivi K., Kuosma E., Sioris T., Salo J., Karjalainen A., Knuutila S., and Anttila S. Increased expression of high mobility group A proteins in lung cancer. J Pathol 209 (2006) 206-212
27. Goodwin G. The high mobility group protein, HMGI-C. Int J Biochem Cell Biol 30 (1998) 761-766
28. Reeves R. Molecular biology of HMGA proteins: hubs of nuclear function. Gene 277 (2001) 63-81
29. Reeves R. Structure and function of the HMGI(Y) family of architectural transcription factors. Environ Health Perspect 108 Suppl. 5 (2000) 803-809
30. Rogalla P., Drechsler K., Schroder-Babo W., Eberhardt K., and Bullerdiek J. HMGIC expression patterns in non-small lung cancer and surrounding tissue. Anticancer Res 18 (1998) 3327-3330